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Cancer risk assessment [[electronic resource] ] : chemical carcinogenesis, hazard evaluation, and risk quantification / / edited by Ching-Hung Hsu, Todd Stedeford
| Cancer risk assessment [[electronic resource] ] : chemical carcinogenesis, hazard evaluation, and risk quantification / / edited by Ching-Hung Hsu, Todd Stedeford |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2010 |
| Descrizione fisica | 1 online resource (858 p.) |
| Disciplina |
616.99/4071
616.994071 |
| Altri autori (Persone) |
HsuChing-Hung
StedefordTodd |
| Soggetto topico |
Carcinogens
Health risk assessment |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-118-03512-7
1-282-68335-7 9786612683350 0-470-62272-5 0-470-62271-7 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
CANCER RISK ASSESSMENT: Chemical Carcinogenesis, Hazard Evaluation, and Risk Quantification; CONTENTS; PREFACE; CONTRIBUTORS; ABBREVIATIONS AND ACRONYMS; PART I: CANCER RISK ASSESSMENT, SCIENCE POLICY, AND REGULATORY FRAMEWORKS; CHAPTER 1: CANCER RISK ASSESSMENT; CHAPTER 2: SCIENCE POLICY AND CANCER RISK ASSESSMENT; CHAPTER 3: HAZARD AND RISK ASSESSMENT OF CHEMICAL CARCINOGENICITY WITHIN A REGULATORY CONTEXT; CHAPTER 4: USE OF CANCER RISK ASSESSMENTS IN DETERMINATION OF REGULATORY STANDARDS; PART II: CANCER BIOLOGY AND TOXICOLOGY; CHAPTER 5: THE INTERPLAY OF CANCER AND BIOLOGY
CHAPTER 6: CHEMICAL CARCINOGENESIS: A BRIEF HISTORY OF ITS CONCEPTS WITH A FOCUS ON POLYCYCLIC AROMATIC HYDROCARBONSCHAPTER 7: HORMESIS AND CANCER RISKS: ISSUES AND RESOLUTION; CHAPTER 8: THRESHOLDS FOR GENOTOXIC CARCINOGENS: EVIDENCE FROM MECHANISM-BASED CARCINOGENICITY STUDIES; PART III: GENETIC TOXICOLOGY, TESTING GUIDELINES AND REGULATIONS, AND NOVEL ASSAYS; CHAPTER 9: DEVELOPMENT OF GENETIC TOXICOLOGY TESTING AND ITS INCORPORATION INTO REGULATORY HEALTH EFFECTS TEST REQUIREMENTS; CHAPTER 10: GENETIC TOXICOLOGY TESTING GUIDELINES AND REGULATIONS; CHAPTER 11: IN VITRO GENOTOX ASSAYS CHAPTER 12: IN VIVO GENOTOXICITY ASSAYSPART IV: ASSESSING THE HUMAN RELEVANCE OF CHEMICAL-INDUCED TUMORS; CHAPTER 13: FRAMEWORK ANALYSIS FOR DETERMINING MODE OF ACTION AND HUMAN RELEVANCE; CHAPTER 14: EXPERIMENTAL ANIMAL STUDIES AND CARCINOGENICITY; CHAPTER 15: CANCER EPIDEMIOLOGY; CHAPTER 16: RODENT HEPATOCARCINOGENESIS; CHAPTER 17: MODE OF ACTION ANALYSIS AND HUMAN RELEVANCE OF LIVER TUMORS INDUCED BY PPAR a ACTIVATION; CHAPTER 18: ALPHA 2U-GLOBULIN NEPHROPATHY AND CHRONIC PROGRESSIVE NEPHROPATHY AS MODES OF ACTION FOR RENAL TUBULE TUMOR INDUCTION IN RATS, AND THEIR POSSIBLE INTERACTION CHAPTER 19: URINARY TRACT CALCULI AND BLADDER TUMORSPART V: METHODS FOR INFORMING CANCER RISK QUANTIFICATION; CHAPTER 20: (Q) SAR ANALYSIS OF GENOTOXIC AND NONGENOTOXIC CARCINOGENS: A STATE-OF-THE-ART OVERVIEW; CHAPTER 21: PHYSIOLOGICALLY BASED PHARMACOKINETIC (PBPK) MODELS IN CANCER RISK ASSESSMENT; CHAPTER 22: GENOMICS AND ITS ROLE IN CANCER RISK ASSESSMENT; CHAPTER 23: COMPUTATIONAL TOXICOLOGY IN CANCER RISK ASSESSMENT; PART VI: GENERAL APPROACHES FOR QUANTIFYING CANCER RISKS; CHAPTER 24: LINEAR LOW-DOSE EXTRAPOLATIONS CHAPTER 25: QUANTITATIVE CANCER RISK ASSESSMENT OF NONGENOTOXIC CARCINOGENSCHAPTER 26: NONLINEAR LOW-DOSE EXTRAPOLATIONS; CHAPTER 27: CANCER RISK ASSESSMENT: MORE UNCERTAIN THAN WE THOUGHT; CHAPTER 28: COMBINING NEOPLASMS FOR EVALUATION OF RODENT CARCINOGENESIS STUDIES; CHAPTER 29: CANCER RISK BASED ON AN INDIVIDUAL TUMOR TYPE OR SUMMING OF TUMORS; CHAPTER 30: EXPOSURE RECONSTRUCTION AND CANCER RISK ESTIMATE DERIVATION; INDEX |
| Record Nr. | UNINA-9910139192103321 |
| Hoboken, N.J., : Wiley, c2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Cancer risk assessment [[electronic resource] ] : chemical carcinogenesis, hazard evaluation, and risk quantification / / edited by Ching-Hung Hsu, Todd Stedeford
| Cancer risk assessment [[electronic resource] ] : chemical carcinogenesis, hazard evaluation, and risk quantification / / edited by Ching-Hung Hsu, Todd Stedeford |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2010 |
| Descrizione fisica | 1 online resource (858 p.) |
| Disciplina |
616.99/4071
616.994071 |
| Altri autori (Persone) |
HsuChing-Hung
StedefordTodd |
| Soggetto topico |
Carcinogens
Health risk assessment |
| ISBN |
1-118-03512-7
1-282-68335-7 9786612683350 0-470-62272-5 0-470-62271-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
CANCER RISK ASSESSMENT: Chemical Carcinogenesis, Hazard Evaluation, and Risk Quantification; CONTENTS; PREFACE; CONTRIBUTORS; ABBREVIATIONS AND ACRONYMS; PART I: CANCER RISK ASSESSMENT, SCIENCE POLICY, AND REGULATORY FRAMEWORKS; CHAPTER 1: CANCER RISK ASSESSMENT; CHAPTER 2: SCIENCE POLICY AND CANCER RISK ASSESSMENT; CHAPTER 3: HAZARD AND RISK ASSESSMENT OF CHEMICAL CARCINOGENICITY WITHIN A REGULATORY CONTEXT; CHAPTER 4: USE OF CANCER RISK ASSESSMENTS IN DETERMINATION OF REGULATORY STANDARDS; PART II: CANCER BIOLOGY AND TOXICOLOGY; CHAPTER 5: THE INTERPLAY OF CANCER AND BIOLOGY
CHAPTER 6: CHEMICAL CARCINOGENESIS: A BRIEF HISTORY OF ITS CONCEPTS WITH A FOCUS ON POLYCYCLIC AROMATIC HYDROCARBONSCHAPTER 7: HORMESIS AND CANCER RISKS: ISSUES AND RESOLUTION; CHAPTER 8: THRESHOLDS FOR GENOTOXIC CARCINOGENS: EVIDENCE FROM MECHANISM-BASED CARCINOGENICITY STUDIES; PART III: GENETIC TOXICOLOGY, TESTING GUIDELINES AND REGULATIONS, AND NOVEL ASSAYS; CHAPTER 9: DEVELOPMENT OF GENETIC TOXICOLOGY TESTING AND ITS INCORPORATION INTO REGULATORY HEALTH EFFECTS TEST REQUIREMENTS; CHAPTER 10: GENETIC TOXICOLOGY TESTING GUIDELINES AND REGULATIONS; CHAPTER 11: IN VITRO GENOTOX ASSAYS CHAPTER 12: IN VIVO GENOTOXICITY ASSAYSPART IV: ASSESSING THE HUMAN RELEVANCE OF CHEMICAL-INDUCED TUMORS; CHAPTER 13: FRAMEWORK ANALYSIS FOR DETERMINING MODE OF ACTION AND HUMAN RELEVANCE; CHAPTER 14: EXPERIMENTAL ANIMAL STUDIES AND CARCINOGENICITY; CHAPTER 15: CANCER EPIDEMIOLOGY; CHAPTER 16: RODENT HEPATOCARCINOGENESIS; CHAPTER 17: MODE OF ACTION ANALYSIS AND HUMAN RELEVANCE OF LIVER TUMORS INDUCED BY PPAR a ACTIVATION; CHAPTER 18: ALPHA 2U-GLOBULIN NEPHROPATHY AND CHRONIC PROGRESSIVE NEPHROPATHY AS MODES OF ACTION FOR RENAL TUBULE TUMOR INDUCTION IN RATS, AND THEIR POSSIBLE INTERACTION CHAPTER 19: URINARY TRACT CALCULI AND BLADDER TUMORSPART V: METHODS FOR INFORMING CANCER RISK QUANTIFICATION; CHAPTER 20: (Q) SAR ANALYSIS OF GENOTOXIC AND NONGENOTOXIC CARCINOGENS: A STATE-OF-THE-ART OVERVIEW; CHAPTER 21: PHYSIOLOGICALLY BASED PHARMACOKINETIC (PBPK) MODELS IN CANCER RISK ASSESSMENT; CHAPTER 22: GENOMICS AND ITS ROLE IN CANCER RISK ASSESSMENT; CHAPTER 23: COMPUTATIONAL TOXICOLOGY IN CANCER RISK ASSESSMENT; PART VI: GENERAL APPROACHES FOR QUANTIFYING CANCER RISKS; CHAPTER 24: LINEAR LOW-DOSE EXTRAPOLATIONS CHAPTER 25: QUANTITATIVE CANCER RISK ASSESSMENT OF NONGENOTOXIC CARCINOGENSCHAPTER 26: NONLINEAR LOW-DOSE EXTRAPOLATIONS; CHAPTER 27: CANCER RISK ASSESSMENT: MORE UNCERTAIN THAN WE THOUGHT; CHAPTER 28: COMBINING NEOPLASMS FOR EVALUATION OF RODENT CARCINOGENESIS STUDIES; CHAPTER 29: CANCER RISK BASED ON AN INDIVIDUAL TUMOR TYPE OR SUMMING OF TUMORS; CHAPTER 30: EXPOSURE RECONSTRUCTION AND CANCER RISK ESTIMATE DERIVATION; INDEX |
| Record Nr. | UNINA-9910830822503321 |
| Hoboken, N.J., : Wiley, c2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Cancer risk assessment : chemical carcinogenesis, hazard evaluation, and risk quantification / / edited by Ching-Hung Hsu, Todd Stedeford
| Cancer risk assessment : chemical carcinogenesis, hazard evaluation, and risk quantification / / edited by Ching-Hung Hsu, Todd Stedeford |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2010 |
| Descrizione fisica | 1 online resource (858 p.) |
| Disciplina | 616.99/4071 |
| Altri autori (Persone) |
HsuChing-Hung
StedefordTodd |
| Soggetto topico |
Carcinogens
Health risk assessment |
| ISBN |
1-118-03512-7
1-282-68335-7 9786612683350 0-470-62272-5 0-470-62271-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
CANCER RISK ASSESSMENT: Chemical Carcinogenesis, Hazard Evaluation, and Risk Quantification; CONTENTS; PREFACE; CONTRIBUTORS; ABBREVIATIONS AND ACRONYMS; PART I: CANCER RISK ASSESSMENT, SCIENCE POLICY, AND REGULATORY FRAMEWORKS; CHAPTER 1: CANCER RISK ASSESSMENT; CHAPTER 2: SCIENCE POLICY AND CANCER RISK ASSESSMENT; CHAPTER 3: HAZARD AND RISK ASSESSMENT OF CHEMICAL CARCINOGENICITY WITHIN A REGULATORY CONTEXT; CHAPTER 4: USE OF CANCER RISK ASSESSMENTS IN DETERMINATION OF REGULATORY STANDARDS; PART II: CANCER BIOLOGY AND TOXICOLOGY; CHAPTER 5: THE INTERPLAY OF CANCER AND BIOLOGY
CHAPTER 6: CHEMICAL CARCINOGENESIS: A BRIEF HISTORY OF ITS CONCEPTS WITH A FOCUS ON POLYCYCLIC AROMATIC HYDROCARBONSCHAPTER 7: HORMESIS AND CANCER RISKS: ISSUES AND RESOLUTION; CHAPTER 8: THRESHOLDS FOR GENOTOXIC CARCINOGENS: EVIDENCE FROM MECHANISM-BASED CARCINOGENICITY STUDIES; PART III: GENETIC TOXICOLOGY, TESTING GUIDELINES AND REGULATIONS, AND NOVEL ASSAYS; CHAPTER 9: DEVELOPMENT OF GENETIC TOXICOLOGY TESTING AND ITS INCORPORATION INTO REGULATORY HEALTH EFFECTS TEST REQUIREMENTS; CHAPTER 10: GENETIC TOXICOLOGY TESTING GUIDELINES AND REGULATIONS; CHAPTER 11: IN VITRO GENOTOX ASSAYS CHAPTER 12: IN VIVO GENOTOXICITY ASSAYSPART IV: ASSESSING THE HUMAN RELEVANCE OF CHEMICAL-INDUCED TUMORS; CHAPTER 13: FRAMEWORK ANALYSIS FOR DETERMINING MODE OF ACTION AND HUMAN RELEVANCE; CHAPTER 14: EXPERIMENTAL ANIMAL STUDIES AND CARCINOGENICITY; CHAPTER 15: CANCER EPIDEMIOLOGY; CHAPTER 16: RODENT HEPATOCARCINOGENESIS; CHAPTER 17: MODE OF ACTION ANALYSIS AND HUMAN RELEVANCE OF LIVER TUMORS INDUCED BY PPAR a ACTIVATION; CHAPTER 18: ALPHA 2U-GLOBULIN NEPHROPATHY AND CHRONIC PROGRESSIVE NEPHROPATHY AS MODES OF ACTION FOR RENAL TUBULE TUMOR INDUCTION IN RATS, AND THEIR POSSIBLE INTERACTION CHAPTER 19: URINARY TRACT CALCULI AND BLADDER TUMORSPART V: METHODS FOR INFORMING CANCER RISK QUANTIFICATION; CHAPTER 20: (Q) SAR ANALYSIS OF GENOTOXIC AND NONGENOTOXIC CARCINOGENS: A STATE-OF-THE-ART OVERVIEW; CHAPTER 21: PHYSIOLOGICALLY BASED PHARMACOKINETIC (PBPK) MODELS IN CANCER RISK ASSESSMENT; CHAPTER 22: GENOMICS AND ITS ROLE IN CANCER RISK ASSESSMENT; CHAPTER 23: COMPUTATIONAL TOXICOLOGY IN CANCER RISK ASSESSMENT; PART VI: GENERAL APPROACHES FOR QUANTIFYING CANCER RISKS; CHAPTER 24: LINEAR LOW-DOSE EXTRAPOLATIONS CHAPTER 25: QUANTITATIVE CANCER RISK ASSESSMENT OF NONGENOTOXIC CARCINOGENSCHAPTER 26: NONLINEAR LOW-DOSE EXTRAPOLATIONS; CHAPTER 27: CANCER RISK ASSESSMENT: MORE UNCERTAIN THAN WE THOUGHT; CHAPTER 28: COMBINING NEOPLASMS FOR EVALUATION OF RODENT CARCINOGENESIS STUDIES; CHAPTER 29: CANCER RISK BASED ON AN INDIVIDUAL TUMOR TYPE OR SUMMING OF TUMORS; CHAPTER 30: EXPOSURE RECONSTRUCTION AND CANCER RISK ESTIMATE DERIVATION; INDEX |
| Record Nr. | UNINA-9910877838303321 |
| Hoboken, N.J., : Wiley, c2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||