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Chemical sensors and biosensors for medical and biological applications / / Ursula E. Spichiger-Keller
Chemical sensors and biosensors for medical and biological applications / / Ursula E. Spichiger-Keller
Autore Spichiger-Keller Ursula E.
Pubbl/distr/stampa [Berlin, Germany] : , : Wiley-VCH, , [2008]
Descrizione fisica 1 online resource (428 p.)
Disciplina 660.6
681.2
Soggetto topico Chemical detectors
Biosensors
Soggetto genere / forma Electronic books.
ISBN 1-282-01030-1
9786612010309
3-527-61228-9
3-527-61226-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Chemical Sensors and Biosensors for Medical and Biological Applications; Preface; Contents; 1 Introduction; 1.1 Chemical Sensors as Alternative Analytical Tools; 1.2 The Concept of Chemical and Biochemical Sensors; 1.3 Recognition Processes and Sensor Technology: Milestones; 1.4 Goals for Future Developments and Trends; 1.4.1 Trends; 1.4.2 Miniatuization Nanotechnology; 1.4.3 In Vivo and In Situ Monitoring; 1.4.4 The Analytical Laboratory in the 21st Century (Conclusions); References; 2 Chemical and Biochemical Sensors; 2.1 Classification, Specification, and Nomenclature of Chemical Sensors
2 2 Molecular Recognition Processes for Ions and Neutral Species2.2.1 Introduction; 2.2.2 Molecular Interactions: Tools and Calculations; 2.2.3 Molecular Recognition of Ions; 2.2.4 Hydrogen Bonds; 2.2.5 Molecular Recognition of Enantiomers; 2.2.6 Molecular Interactions within the Aqueous Medium; 2.2.7 Catalysis by Enzymes, Enzyme Mimics and Host-Reactands; 2.2.8 Catalytic Antibodies; 2.2.9 Multitopic Recognition of Immunological Systems; 2.2.10 Conclusions and Considerations for Ligand Design; References; 3 Controlling Sensor Reactions
3.1 Thermodynamically Controlled Sensor Reactions: Reversibility and Thermodynamic Equilibrium3.1.1 The Chemical Potential and the Partition Equilibrium; 3.1.2 The Recognition and Transduction Process; 3.1.3 The Electrochemical Potential and the (Potentiometric) Sensor Response; 3.2 Thermodynamics of Nonequilibria: Diffusion and Steady-State; 3.3 Rate-Controlled Sensor Reactions: Mediated Enzyme Reactions; 3.4. Nonthermodynamic Assumptions; 3.4.1 Activity Versus Concentrations; 3.4.2 Ionic Strength and Estimates of Activity Coefficients
3.4.3 Activity and Concentration of an Electrolyte: IFCC / IUPAC Definitions3.4.4 The Osmotic Coefficient; 3.4.5 Calibration, Standardization, and Comparisons with Definitive or Reference Procedures; 3.4.6 The Liquid Junction Potential under Physiological Conditions; References; 4 The Artificial Analyte-Selective Membrane Limitations, Technological Precautions and Developments; 4.1 Introduction; 4.2 Types of Membranes and Membrane Models; 4.2.1 The Biological Membrane; 4.2.2 Artificial Membranes; 4.3 The Selectivity Coefficient; 4.4 The Membrane Composition and the Membrane Medium
4.4.1 The Influence of the Permittivity and of Plasticizers4.4.2 The Effect of Electron Pair Donor (EPD) and Acceptor (EPA) . Properties of Solvents . Solubilization Properties of the Membrane; 4.4.3 The Influence of the Aqueous Sample Environment; 4.4.4 The Influence of the Surface Tension; 4.4.5 The Effect of Lipophilic Anionic Sites; 4.4.6 The Effect of the Ligand Concentration; 4.5 Response Behavior, Sensitivity, and Detection Limit; 4.6 Lifetime,Lipophilicity, and Immobilization; 4.7 Interactions by the Biological Matrix and Precautions; 4.7.1 Biocompatibility
4.7.2 Possible Mechanism of Protein Adsorption
Record Nr. UNINA-9910143968403321
Spichiger-Keller Ursula E.  
[Berlin, Germany] : , : Wiley-VCH, , [2008]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Chemical sensors and biosensors for medical and biological applications / / Ursula E. Spichiger-Keller
Chemical sensors and biosensors for medical and biological applications / / Ursula E. Spichiger-Keller
Autore Spichiger-Keller Ursula E.
Pubbl/distr/stampa [Berlin, Germany] : , : Wiley-VCH, , [2008]
Descrizione fisica 1 online resource (428 p.)
Disciplina 660.6
681.2
Soggetto topico Chemical detectors
Biosensors
ISBN 1-282-01030-1
9786612010309
3-527-61228-9
3-527-61226-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Chemical Sensors and Biosensors for Medical and Biological Applications; Preface; Contents; 1 Introduction; 1.1 Chemical Sensors as Alternative Analytical Tools; 1.2 The Concept of Chemical and Biochemical Sensors; 1.3 Recognition Processes and Sensor Technology: Milestones; 1.4 Goals for Future Developments and Trends; 1.4.1 Trends; 1.4.2 Miniatuization Nanotechnology; 1.4.3 In Vivo and In Situ Monitoring; 1.4.4 The Analytical Laboratory in the 21st Century (Conclusions); References; 2 Chemical and Biochemical Sensors; 2.1 Classification, Specification, and Nomenclature of Chemical Sensors
2 2 Molecular Recognition Processes for Ions and Neutral Species2.2.1 Introduction; 2.2.2 Molecular Interactions: Tools and Calculations; 2.2.3 Molecular Recognition of Ions; 2.2.4 Hydrogen Bonds; 2.2.5 Molecular Recognition of Enantiomers; 2.2.6 Molecular Interactions within the Aqueous Medium; 2.2.7 Catalysis by Enzymes, Enzyme Mimics and Host-Reactands; 2.2.8 Catalytic Antibodies; 2.2.9 Multitopic Recognition of Immunological Systems; 2.2.10 Conclusions and Considerations for Ligand Design; References; 3 Controlling Sensor Reactions
3.1 Thermodynamically Controlled Sensor Reactions: Reversibility and Thermodynamic Equilibrium3.1.1 The Chemical Potential and the Partition Equilibrium; 3.1.2 The Recognition and Transduction Process; 3.1.3 The Electrochemical Potential and the (Potentiometric) Sensor Response; 3.2 Thermodynamics of Nonequilibria: Diffusion and Steady-State; 3.3 Rate-Controlled Sensor Reactions: Mediated Enzyme Reactions; 3.4. Nonthermodynamic Assumptions; 3.4.1 Activity Versus Concentrations; 3.4.2 Ionic Strength and Estimates of Activity Coefficients
3.4.3 Activity and Concentration of an Electrolyte: IFCC / IUPAC Definitions3.4.4 The Osmotic Coefficient; 3.4.5 Calibration, Standardization, and Comparisons with Definitive or Reference Procedures; 3.4.6 The Liquid Junction Potential under Physiological Conditions; References; 4 The Artificial Analyte-Selective Membrane Limitations, Technological Precautions and Developments; 4.1 Introduction; 4.2 Types of Membranes and Membrane Models; 4.2.1 The Biological Membrane; 4.2.2 Artificial Membranes; 4.3 The Selectivity Coefficient; 4.4 The Membrane Composition and the Membrane Medium
4.4.1 The Influence of the Permittivity and of Plasticizers4.4.2 The Effect of Electron Pair Donor (EPD) and Acceptor (EPA) . Properties of Solvents . Solubilization Properties of the Membrane; 4.4.3 The Influence of the Aqueous Sample Environment; 4.4.4 The Influence of the Surface Tension; 4.4.5 The Effect of Lipophilic Anionic Sites; 4.4.6 The Effect of the Ligand Concentration; 4.5 Response Behavior, Sensitivity, and Detection Limit; 4.6 Lifetime,Lipophilicity, and Immobilization; 4.7 Interactions by the Biological Matrix and Precautions; 4.7.1 Biocompatibility
4.7.2 Possible Mechanism of Protein Adsorption
Record Nr. UNINA-9910830428303321
Spichiger-Keller Ursula E.  
[Berlin, Germany] : , : Wiley-VCH, , [2008]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui