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Drug Absorption Studies: In Situ, In Vitro and In Silico Models
| Drug Absorption Studies: In Situ, In Vitro and In Silico Models |
| Autore | Song Im-Sook |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (171 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
rebamipide
nanocrystals oral mucositis hydrogel endocytosis enoxaparin lipid–polymer hybrid nanoparticles oral intestinal absorption naftidrofuryl oxalate solubility permeability dissolution profiles pharmaceutical availability BCS drug classification non-sink condition solubility–permeability interplay unstirred water layer poorly soluble drugs solubilizer additive phenylketonuria l-phenylalanine ammonia-lyase enzyme kinetics catabolism disorder biomedical drug P-glycoprotein breast cancer resistance protein LY335979 WK-X-34 in vivo–in vitro correlation lipolysis-permeation lipid-based drug delivery system PermeaPad cinnarizine lipolysis amorphous solid dispersion candesartan Cilexetil PVPK30 pH-modulation spray drying bioavailability nasal administration spray-drying chitosan microsphere meloxicam silymarin D-α-Tocopherol polyethylene glycol 1000 succinate (TPGS) liver distribution acetaminophen-induced hepatotoxicity extra virgin olive oil secoiridoids metabolism phenolic compounds intestinal permeability drug-phytochemical interaction hepatic metabolism mixed inhibition quercetin repaglinide |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Drug Absorption Studies |
| Record Nr. | UNINA-9910557689203321 |
Song Im-Sook
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug Metabolism/Transport and Pharmacokinetics
| Drug Metabolism/Transport and Pharmacokinetics |
| Autore | Song Im-Sook |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (232 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
tofacitinib
dose-dependent pharmacokinetics hepatic and intestinal first-pass effect rats catalposide in vitro human metabolism UDP-glucuronosyltransferase sulfotransferase carboxylesterase celecoxib drug–drug interaction fluorescence HPLC metabolism repaglinide HSG4112 anti-obesity agent stereoselectivity pharmacokinetics compound K protopanaxadiol (PPD) biliary excretion intestinal metabolism Carthamus tinctorius extract notoginseng total saponins comparative pharmacokinetic study large volume direct injection compatibility mechanism mertansine human hepatocytes cytochrome P450 UDP-glucuronosyltransferases sodium-glucose cotransporter 2 (SGLT2) inhibitors DWP16001 kidney distribution inhibition mode diabetes transporter-enzyme interplay influx transporter efflux transporter physiologically based pharmacokinetic model cytochrome P450 enzymes tiropramide healthy Korean subjects modeling population pharmacokinetic quercetin breast cancer resistance protein inhibitor prazosin sulfasalazine kinetic analysis food–drug interactions Caco-2 EpiIntestinal first-pass P-gp BCRP drug transporter CYP3A4 oral availability automatization drug absorption drug dosing head-and-neck cancer real-time measurements taxanes tissue engineering UHPLC-MS/MS metformin verapamil drug interaction organic cation transporter 2 renal excretion acute renal failure gentamicin cisplatin hepatic CYP3A1(23) creatinine clearance renal clearance nonrenal clearance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557607703321 |
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Song Im-Sook
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||