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The quantal theory of immunity [[electronic resource] ] : the molecular basis of autoimmunity and leukemia / / Kendall A. Smith
| The quantal theory of immunity [[electronic resource] ] : the molecular basis of autoimmunity and leukemia / / Kendall A. Smith |
| Autore | Smith Kendall A |
| Pubbl/distr/stampa | Singapore ; ; Hackensack, N.J., : World Scientific, 2010 |
| Descrizione fisica | 1 online resource (200 p.) |
| Disciplina |
616.079
616.97/8 616.978 |
| Soggetto topico |
Immune response
Interleukin-2 T cells |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-283-14368-2
9786613143686 981-4271-76-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Acknowledgements; Prologue; Contents; Chapter 1 Introduction - The Evolution of Our Understanding of the Immune System; Chapter 2 Molecular Immunology; Chapter 3 The Problem - Understanding How Molecules Direct the Behavior of Cells Comprising the Immune System; Chapter 4 The Quantal Theory of Immunity; Chapter 5 The Variability of Cell Cycle Progression and the Competence and Progression Phases of the Cell Cycle; Chapter 6 The Quantal Nature of IL-2-Promoted T Cell Cycle Progression
Chapter 7 The Molecular Basis for Quantal IL-2/IL-2R Signaling of Cell Cycle Progression - TheIL-2/Receptor InteractionChapter 8 The Molecular Basis for Quantal IL-2/IL-2R Signaling of Cell CycleProgression - IL-2 and IL-2 Receptor Metabolism; Chapter 9 The Molecular Basis for Quantal IL-2/IL-2R Signaling of Cell Cycle Progression - IL-2 Receptor Signaling viathe Jak/Stat Pathway; Chapter 10 The Molecular Basis for Quantal IL-2/IL-2R Signaling of Cell Cycle Progression - IL-2 Receptor Signaling via Phospho Chapter 11 The T Cell Antigen Receptor Complex and the Quantal Regulation of the IL-2 and IL-2R GenesChapter 12 Digital Signaling via the T Cell Antigen Receptor Complex; Chapter 13 Negative Feedback Regulation of T Cell Antigen Receptor Complex Signaling - Attenuation of IL-2Gene Expression; Chapter 14 The Paradox of the IL-2 (-/-) Mouse; Chapter 15 The Scurfy Mouse; Chapter 16 Lymphopenia, Autoimmunity and the Regulatory T Cell (Treg); Chapter 17 Treg-mediated "Active Suppression" of T Cell Proliferation; Chapter 18 FOXP3, A Better ID-Tag for Tregs?; Chapter 19 Mice Versus Men Chapter 20 Active Versus Passive Suppression and IL-2 MetabolismChapter 21 FOXP3 Restricts But Does Not Suppress IL-2 Production; Chapter 22 Both the TCR and IL-2 Regulate FOXP3 Expression; Chapter 23 The Effects of FOXP3 Expression; Chapter 24 The Role of IL-2 in the Generation of Immune Responses In Vivo; Chapter 25 The Role of the IL-2r Chains in IL-2 Signaling, Consumption and Suppression of T Cell Proliferation; Chapter 26 T Cell Tissue-specific Autoimmunity; Chapter 27 Type 1 Diabetes Mellitus (T1DM), a Prototypic Genetic Autoimmune Disease with a Tie to IL-2 Chapter 28 The Pathogenesis of Leukemia - Loss of Normal Quantal Growth ControlEpilogue; Index |
| Record Nr. | UNINA-9910463949903321 |
Smith Kendall A
|
||
| Singapore ; ; Hackensack, N.J., : World Scientific, 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The quantal theory of immunity [[electronic resource] ] : the molecular basis of autoimmunity and leukemia / / Kendall A. Smith
| The quantal theory of immunity [[electronic resource] ] : the molecular basis of autoimmunity and leukemia / / Kendall A. Smith |
| Autore | Smith Kendall A |
| Pubbl/distr/stampa | Singapore ; ; Hackensack, N.J., : World Scientific, 2010 |
| Descrizione fisica | 1 online resource (200 p.) |
| Disciplina |
616.079
616.97/8 616.978 |
| Soggetto topico |
Immune response
Interleukin-2 T cells |
| ISBN |
1-283-14368-2
9786613143686 981-4271-76-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Acknowledgements; Prologue; Contents; Chapter 1 Introduction - The Evolution of Our Understanding of the Immune System; Chapter 2 Molecular Immunology; Chapter 3 The Problem - Understanding How Molecules Direct the Behavior of Cells Comprising the Immune System; Chapter 4 The Quantal Theory of Immunity; Chapter 5 The Variability of Cell Cycle Progression and the Competence and Progression Phases of the Cell Cycle; Chapter 6 The Quantal Nature of IL-2-Promoted T Cell Cycle Progression
Chapter 7 The Molecular Basis for Quantal IL-2/IL-2R Signaling of Cell Cycle Progression - TheIL-2/Receptor InteractionChapter 8 The Molecular Basis for Quantal IL-2/IL-2R Signaling of Cell CycleProgression - IL-2 and IL-2 Receptor Metabolism; Chapter 9 The Molecular Basis for Quantal IL-2/IL-2R Signaling of Cell Cycle Progression - IL-2 Receptor Signaling viathe Jak/Stat Pathway; Chapter 10 The Molecular Basis for Quantal IL-2/IL-2R Signaling of Cell Cycle Progression - IL-2 Receptor Signaling via Phospho Chapter 11 The T Cell Antigen Receptor Complex and the Quantal Regulation of the IL-2 and IL-2R GenesChapter 12 Digital Signaling via the T Cell Antigen Receptor Complex; Chapter 13 Negative Feedback Regulation of T Cell Antigen Receptor Complex Signaling - Attenuation of IL-2Gene Expression; Chapter 14 The Paradox of the IL-2 (-/-) Mouse; Chapter 15 The Scurfy Mouse; Chapter 16 Lymphopenia, Autoimmunity and the Regulatory T Cell (Treg); Chapter 17 Treg-mediated "Active Suppression" of T Cell Proliferation; Chapter 18 FOXP3, A Better ID-Tag for Tregs?; Chapter 19 Mice Versus Men Chapter 20 Active Versus Passive Suppression and IL-2 MetabolismChapter 21 FOXP3 Restricts But Does Not Suppress IL-2 Production; Chapter 22 Both the TCR and IL-2 Regulate FOXP3 Expression; Chapter 23 The Effects of FOXP3 Expression; Chapter 24 The Role of IL-2 in the Generation of Immune Responses In Vivo; Chapter 25 The Role of the IL-2r Chains in IL-2 Signaling, Consumption and Suppression of T Cell Proliferation; Chapter 26 T Cell Tissue-specific Autoimmunity; Chapter 27 Type 1 Diabetes Mellitus (T1DM), a Prototypic Genetic Autoimmune Disease with a Tie to IL-2 Chapter 28 The Pathogenesis of Leukemia - Loss of Normal Quantal Growth ControlEpilogue; Index |
| Record Nr. | UNINA-9910788570503321 |
|
Smith Kendall A
|
||
| Singapore ; ; Hackensack, N.J., : World Scientific, 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||