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Bacteriophage Applications - Historical Perspective and Future Potential / / by Jessica Nicastro, Shirley Wong, Zahra Khazaei, Peggy Lam, Jonathan Blay, Roderick A. Slavcev
| Bacteriophage Applications - Historical Perspective and Future Potential / / by Jessica Nicastro, Shirley Wong, Zahra Khazaei, Peggy Lam, Jonathan Blay, Roderick A. Slavcev |
| Autore | Nicastro Jessica |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (VII, 82 p.) |
| Disciplina | 576.6482 |
| Collana | SpringerBriefs in Biochemistry and Molecular Biology |
| Soggetto topico |
Biochemical engineering
Combinatorial chemistry Gene expression Biochemical Engineering Combinatorial Libraries Gene Expression |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. Introduction: What are Bacteriophage: a. Discovery and early phage work (including work with bacterial genetics, phage display, and phage therapy) -- b. Bacteriophage pathogenesis and host range -- c. Bacteriophage growth dynamics -- d. Bacteriophage pharmacokinetics( including mammalian host tolerance ) -- 2. Applications with Bacteriophage: a. Phage Therapy -- i. Past – why phage therapy was unsuccessful in the past and what can (and is currently) being done to improve the system -- ii. Present /Future – current research objectives and future considerations -- Host range and how it can be expanded -- Lethal agent delivery systems (bacteriocidial) -- Lethality without lysis -- b. Phage Vaccines and Phage Immunostimulation -- i. Mammalian immune response to phage -- ii. Phage vaccine delivery vehicles -- iii. Phage Immunotherapy -- c. Phage as Delivery Vehicles: i. Phage for gene delivery -- Phage display for specific cell targeting -- Considerations for use and benefits in comparison to current systems -- ii. Phage as Drug Carriers -- Selectivity and cell attachment -- Phage T2 as a potential cancer therapeutic -- Phage for delivery to the brain and CNS (including current work with Alzheimer’s and drug addictions ) -- d. Phage for Bacterial Detection: i. History of Phage bacterial detection -- ii. Methods (replication assays, conjugation with bioluminescence, labelling etc. ) -- iii. Potential uses in healthcare and industry -- e. Phage for the targeting of Biofilms -- i. Phage candidates and important bacterial targets -- ii. History and potential uses in healthcare and industry -- f. Phage device coatings: i. Current phage coating practices and research -- ii. Callenges (notably phage orientation) -- iii. methods to overcome these challenges. |
| Record Nr. | UNINA-9910254050703321 |
Nicastro Jessica
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| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nanomedicine : Gene Delivery, Imaging and Evaluation Systems / / edited by Roderick A. Slavcev, Shawn Wettig, Zhiheng Zeng
| Nanomedicine : Gene Delivery, Imaging and Evaluation Systems / / edited by Roderick A. Slavcev, Shawn Wettig, Zhiheng Zeng |
| Edizione | [1st ed. 2018.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
| Descrizione fisica | 1 online resource (V, 125 p. 39 illus., 28 illus. in color.) |
| Disciplina | 610.28 |
| Collana | Experientia Supplementum |
| Soggetto topico |
Medicine - Research
Biology - Research Medical genetics Biotechnology Biomedical Research Clinical Genetics |
| ISBN | 3-319-78259-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1. Introduction -- Chapter 2. Non-Viral Gene Delivery -- Chapter 3. Specific Systems for Imaging -- Chapter 4. Specific Systems for Imaging -- Chapter 5. Conclusions and Perspective. |
| Record Nr. | UNINA-9910298398303321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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