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Blockchain with Artificial Intelligence for Healthcare : A Synergistic Approach
| Blockchain with Artificial Intelligence for Healthcare : A Synergistic Approach |
| Autore | Malviya Rishabha |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Bristol : , : Institute of Physics Publishing, , 2023 |
| Descrizione fisica | 1 online resource (209 pages) |
| Disciplina | 610.285 |
| Altri autori (Persone) |
SinghArun Kumar
SundramSonali BalusamyBalamurugan KadrySeifedine |
| Collana | IOP Ebooks Series |
| ISBN | 0-7503-5841-6 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910915779203321 |
Malviya Rishabha
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| Bristol : , : Institute of Physics Publishing, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Control applications in modern power system : select proceedings of EPREC 2020 / / Arun Kumar Singh, Manoj Tripathy, editors
| Control applications in modern power system : select proceedings of EPREC 2020 / / Arun Kumar Singh, Manoj Tripathy, editors |
| Edizione | [1st ed. 2021.] |
| Pubbl/distr/stampa | Singapore : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (XIII, 535 p. 306 illus., 233 illus. in color.) |
| Disciplina | 621.31 |
| Collana | Lecture Notes in Electrical Engineering |
| Soggetto topico | Electric power systems - Control |
| ISBN | 981-15-8815-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Close Loop Control Of Non-Ideal Buck Converter With Type-III Compensator -- Vector Error Correction Model for Distribution Dynamic State Estimation -- Optimal Battery Charging Forecasting Algorithms for Domestic Applications and Electric Vehicles by Comprehending Sustainable Energy -- Performance Index Based Coordinated Control Strategy for Simultaneous Frequency and Voltage Stabilization of Multi-area Interconnected System -- Load Frequency Control of Two Area Power System by Using 2 Degree of Freedom PID Controller Designed with the Help of Firefly Algorithm. |
| Record Nr. | UNINA-9910483133703321 |
| Singapore : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Multi-drug resistance in cancer : mechanism and treatment strategies / / edited by Rishabha Malviya, Arun Kumar Singh, and Deepika Yadav
| Multi-drug resistance in cancer : mechanism and treatment strategies / / edited by Rishabha Malviya, Arun Kumar Singh, and Deepika Yadav |
| Pubbl/distr/stampa | Hoboken, NJ : , : John Wiley & Sons, , [2023] |
| Descrizione fisica | 1 online resource (216 pages) |
| Disciplina | 614.5999 |
| Soggetto topico |
Multidrug resistance
Drug resistance in cancer cells Drug interactions |
| Soggetto non controllato |
Pharmacology
Medical |
| ISBN |
1-394-20986-X
1-394-20985-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover -- Title Page -- Copyright Page -- Contents -- Foreword -- Preface -- Acknowledgment -- Chapter 1 Multi-Drug Rmesistance in Cancer: Understanding of Treatment Strategies -- 1.1 Introduction -- 1.2 Both Congenital and Developed Resistance to Drugs -- 1.2.1 Intrinsic Resistance -- 1.2.2 Acquired Resistance -- 1.3 Drug-Resistance Mechanisms -- 1.3.1 Increased Efflux of Drugs -- 1.3.2 Impact on Medication Target -- 1.3.3 Improved DNA-Damage Repair -- 1.4 Senescence Escape -- 1.5 Epigenetic Alterations -- 1.6 Tumor Heterogeneity -- 1.7 Tumor Microenvironment -- 1.8 Epithelial to Mesenchymal Transition -- 1.9 Conclusion -- References -- Chapter 2 Understanding Different Mechanisms Involved in Cancer Drug Resistance: Proposing Novel Strategies to Overcome MDR -- 2.1 Introduction -- 2.2 Drug Resistance: Internal and External Variables -- 2.2.1 Phenotypic Variation of Tumors -- 2.2.2 Tumor Microenvironment -- 2.2.3 Cancer Stem Cells -- 2.2.4 Inactivation of the Anticancer Drugs -- 2.2.5 Multi-Drug Resistance -- 2.2.6 Increasing the Release of Drugs Outside the Cell -- 2.2.7 Reducing the Absorption of the Drugs -- 2.2.8 Inhibition of Cell Death (Apoptosis Pathway Blocking) -- 2.3 Improving the Pharmacokinetics -- 2.4 Changing the Aim of the Chemotherapy Agents -- 2.5 Improving the DNA Repair Process -- 2.5.1 Augmentation of a Gene -- 2.5.2 Epigenetic Altering Caused Drug Resistance -- 2.6 MicroRNA in Cancer Drug Resistance -- 2.7 Conclusion -- References -- Chapter 3 Molecular Mechanism of Multi-Drug Resistant Cancer Cells -- 3.1 Introduction -- 3.2 Types of Drug Resistance -- 3.3 Mechanisms of Drug Resistance -- 3.3.1 Drug Efflux via ABC Transporters -- 3.3.2 Permeability Glycoprotein/MDR-1 -- 3.3.3 Multi-Drug Resistance Protein -- 3.3.4 Breast Cancer Resistance Protein -- 3.4 Reduction in Drug Activity and Cellular Absorption.
3.5 Instability in the Genome and Medication Resistance -- 3.5.1 Mutation and Medication Target Alteration -- 3.5.2 Restoration of DNA Integrity -- 3.5.3 Resistant Genes and Epigenetic Modifications -- 3.5.4 Drug Resistance and Programmed Cell Death -- 3.6 RNA Interference Therapy -- 3.7 Methods of Physical Intervention to Treat MDR -- 3.8 Conclusion -- References -- Chapter 4 Natural Products for Clinical Management of Drug Resistant Cancer Cells -- 4.1 Introduction -- 4.2 Resistance Mechanisms -- 4.3 Antitumor Plants for Multi-Drug-Resistant Cells -- 4.4 Qualea Species and Their Medical Applications -- 4.5 Antitumor Activity of Qualea Grandiflora and Qualea Multiflora -- 4.6 Conclusion -- References -- Chapter 5 Understanding of Autophagy to Combat MDR During Anticancer Therapy -- 5.1 Introduction -- 5.2 Mechanisms of Autophagy -- 5.2.1 Phagophore Assembly -- 5.2.2 Autophagosome Formation and Maturation -- 5.2.3 Autolysosome Degradation -- 5.2.4 Core Regulator of Autophagy -- 5.3 Mechanisms of MDR -- 5.4 Correlation Between Autophagy and Multi-Drug Resistance -- 5.5 The Cytoprotective Effect of Autophagy in the Regulation of Multi-Drug Resistance -- 5.6 Increased Autophagy Facilitates Multi-Drug Resistance -- 5.7 Autophagy Inhibition Improves Chemotherapy in MDR Cancers -- 5.8 Overcoming MDR With Autophagic Cell Death -- 5.9 Autophagy Kills Apoptosis-Deficient MDR Cancer Cells -- 5.10 Autophagy Promotes Chemosensitivity -- 5.11 Conclusion -- References -- Chapter 6 Transporter Inhibitors: A Chemotherapeutic Regimen to Improve the Clinical Outcome of Colorectal Cancer -- 6.1 Introduction -- 6.2 CRC Transporters or ATP-Binding Cassette -- 6.2.1 ABC Transporter Family -- 6.2.2 ABC Transporters and CRC Initiation -- 6.2.3 ABC Transporters and the Resistance of Cancer Cells to Chemotherapy. 6.3 Clinical Evidence for the Function of ABC Transporters in CRC MDR -- 6.3.1 Intrinsic Drug Resistance in Colon Cancer Upregulation of P-gp at Detection -- 6.3.2 Proliferating Tumor Cells Have MRP1 on Their Surface -- 6.4 General Approaches -- 6.5 By Blocking Tyrosine Kinase Inhibitors from Inhibiting MDR Transporters -- 6.6 Components Produced from Natural Sources that Inhibit MDR Transporters -- 6.7 Inhibiting ABC Transporters in Other Ways for CRC MDR Circumvention -- 6.8 Challenges and Future Prospective -- 6.9 Conclusion -- References -- Chapter 7 Epithelial to Mesenchymal Transition (EMT): Major Contribution to Cancer Drug Therapy Resistance -- 7.1 Introduction -- 7.2 EMT and Tumor Resistance: In Vitro, In Vivo, and Clinical Trials -- 7.3 Tumor Microenvironment Regulates EMT -- 7.3.1 Hypoxia -- 7.3.2 The Extracellular Matrix -- 7.3.3 The Inflammatory and Immune Microenvironment -- 7.3.4 EMT Microenvironment: Medication Resistance -- 7.4 Drug Resistance and EMT Bioinformatics -- 7.4.1 Bioinformatics and Pharmacogenomics to Optimize Drugs and Targets and Identify Medication Resistance -- 7.4.2 Drug Resistance: Hereditary or Acquired -- 7.4.3 Therapies for EMT-Induced Medication Resistance -- 7.5 Conclusion -- References -- Chapter 8 Advances in Metallodrug-Driven Combination Therapy for Treatment of Cancer -- 8.1 Introduction -- 8.2 Cancer Treatment Using Combination Therapy -- 8.3 Combined Treatment with Metallodrugs for Cancer Treatment -- 8.3.1 Platinum Metallodrugs -- 8.4 Nonplatinum Metallodrugs -- 8.5 Conclusion -- References -- Chapter 9 Novel Strategies Preventing Emergence of MDR in Breast Cancer -- 9.1 Introduction -- 9.2 Breast Cancer Categorization and Epidemiological Studies -- 9.2.1 Treatment Options for Women With Breast Cancer -- 9.3 Multi-Drug Resistance in Breast Cancer -- 9.3.1 Breast Cancer Chemoresistance. 9.3.2 Multi-Drug Resistance and ABC Channels in Breast Cancer -- 9.4 Drug Efflux Transporters in Breast Cancer -- 9.4.1 Exocytosis Transporters in the Stem Cell Population of Breast Cancer -- 9.4.2 Drug Efflux Channel Upregulation in Breast Cancer -- 9.4.3 Techniques for Breast Cancer MDR Reversal -- 9.4.4 Direct Pharmacologic Inhibition With MDR Inhibitors -- 9.5 Excessive Synthesis or Overexpression of Transporters for the Expulsion of Drugs -- 9.6 Nanotherapeutic Approach for MDR Reversal -- 9.7 Breast Cancer's MDR Cure Problems and Future Outlook -- 9.8 Conclusion -- References -- Index -- EULA. |
| Record Nr. | UNINA-9910830428803321 |
| Hoboken, NJ : , : John Wiley & Sons, , [2023] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent advances in power electronics and drives : select proceedings of EPREC 2021 / / Shailendra Kumar, Bhim Singh, and Arun Kumar Singh
| Recent advances in power electronics and drives : select proceedings of EPREC 2021 / / Shailendra Kumar, Bhim Singh, and Arun Kumar Singh |
| Autore | Kumar Shailendra |
| Pubbl/distr/stampa | Singapore : , : Springer, , [2022] |
| Descrizione fisica | 1 online resource (641 pages) |
| Disciplina | 621.317 |
| Collana | Lecture Notes in Electrical Engineering |
| Soggetto topico |
Electric power systems - Control
Power electronics |
| ISBN |
981-16-9238-6
981-16-9239-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Contents -- About the Editors -- Fuzzy Controlled Multi-converter-UPQC for Power Quality Improvement in Distribution System -- 1 Introduction -- 2 Literature Survey -- 2.1 Related Works -- 2.2 Review -- 3 Power Quality Improvement Using Improved MC-UPQC -- 3.1 MC-UPQC -- 3.2 Control Strategies -- 4 Fuzzy Controller-Based MC-UPQC for Power Quality Improvement -- 4.1 Proposed Fuzzy Controller -- 5 Results and Discussions -- 5.1 Simulation Setup -- 5.2 MC-UPQC Performance in Connection with Feeder 1 with Different Controllers -- 5.3 MC-UPQC Performance in Connection with Feeder 2 with Different Controllers -- 5.4 Harmonic Analysis -- 6 Conclusion -- References -- Modified BBO-Based PV Integrated Reduced Component Multilevel Inverter for Mitigating THD -- 1 Introduction -- 2 Description of the Photovoltaic System -- 3 Proposed Topology of Single Phase 5-Level MLI -- 4 Selective Harmonic Elimination as an Optimization Problem -- 5 Brief Discussion on Biogeography-Based Optimization -- 6 The Proposed Technique -- 6.1 Flowchart for Firing Angle Optimization -- 7 Hardware in Loop (HIL) -- 8 Simulation Details -- 9 Results and Discussions -- 9.1 Comparison of Reduced Switch MLIs with the Proposed MLI Topology -- 9.2 Comparison of Results of Different Optimization Techniques with the Proposed MBBO -- 9.3 Hardware in Loop (HIL) Validated Results -- 10 Conclusions -- References -- Power Quality Improvement of an Interconnected Grid System Using PWM Technique of D-STATCOM -- 1 Introduction -- 2 Operation and Control of DSTATCOM -- 3 Modeling -- 4 Controller Design -- 4.1 Current Controller Design -- 4.2 Voltage Controller Design -- 5 Simulation Results -- 6 Conclusion -- References -- Speed Control of a Three-Phase IM with Closed-Loop Control Scheme -- 1 Introduction -- 2 Sinusoidal PWM Technique -- 3 Simulation Result and Discussion for SPWM Scheme.
4 Advantages of Sinusoidal SPWM Scheme -- 5 Speed Control by Closed-Loop V/F Approach -- 6 Result and Discussion for Closed-Loop V/F Control Method -- 7 Advantages of Closed-Loop V/F Control Method -- 8 Conclusion -- References -- A Review on Recent Technologies in Power Electronic Drives for Hybrid Electric Vehicles -- 1 Introduction -- 2 Types of Motors and Power Electronic Interface Circuits -- 3 Configuration of the EVs -- 4 Electric Propulsion System of HEVs -- 5 Conclusion -- References -- Comparative THD Analysis of Multilevel Inverter Using Different Multicarrier PWM Schemes -- 1 Introduction -- 2 Cascaded H-bridge MLI -- 3 Problem Definition -- 4 Sinusoidal PWM Scheme for Inverter -- 5 Multicarrier PWM (MCPWM) Scheme for Inverter -- 6 Benefits of IPD Modulation Technique -- 7 Simulation Result -- 8 Conclusion -- References -- Design and Implementation of Two-Phase Interleaved Boost Converter with Voltage Multiplier for Fuel Cell Hybrid Electric Vehicles -- 1 Introduction -- 2 Modeling of the Converter -- 3 Design and Working of the Converter -- 4 Operation of the Converter -- 4.1 First Stage: t1-t0 -- 4.2 Second Stage: t2-t1 -- 4.3 Third Stage: t3-t2 -- 4.4 Fourth Stage: t4-t3 -- 4.5 First Stage: t1-t0 -- 4.6 Second Stage: t2-t1 -- 4.7 Third Stage: t3-t2 -- 4.8 Third Stage: t4-t3 -- 5 Proposed Converter Design -- 5.1 Static Gain of the Boost Converter -- 5.2 Magnitude of the Passive Components -- 6 Experimental Results -- 7 Conclusion -- References -- A Unipolar Phase Disposition PWM Technique for Reduced Switch Count Symmetrical Nine-Level Multilevel DC Link Inverter Topology -- 1 Introduction -- 2 Description of MLDCL Topology -- 3 Proposed Control Scheme -- 4 Simulation Results and Discussion -- 5 Conclusion -- References -- A Novel Current Control Scheme for Three-Phase Three-Level Grid-Tied Neutral Point Clamped Inverter. 1 Introduction -- 2 Description of NPC Inverter and Its Operation -- 3 Proposed Control Technique -- 4 Simulation Results and Their Analysis -- 5 Conclusion -- References -- Active and Reactive Power Control of Grid-Tied Asymmetrical MLI-based PV System with Reduced Switching Frequency -- 1 Introduction -- 2 Grid-tied PV System with Asymmetrical Multi Level Inverter -- 2.1 Carrier-Based LS-PWM Technique -- 2.2 Control Strategy for Grid-Tied Asymmetrical MLI Based Solar Photo Voltaic System -- 3 Principle of Model Predictive Controller -- 4 Proposed Control Algorithm -- 4.1 Predictive Grid Current Tracking and Maintain UPF -- 4.2 Controlling of Active and Reactive Powers Using MPC -- 4.3 Switching Frequency Reduction -- 5 Simulation Results -- 5.1 Only Reactive Power Control Technique -- 5.2 Real and Reactive Power Control Technique -- 5.3 Load Variation -- 5.4 Reduction of Switching Frequency -- 6 Conclusion -- References -- Modelling and Control Aspects of STATCOM Connected to a Grid-Integrated PV System -- 1 Introduction -- 2 STATCOM Operations in Microgrid -- 3 System Description -- 3.1 PV Array -- 3.2 VSI Based STATCOM -- 4 Control Scheme for PV-Integrated STATCOM -- 4.1 MPPT and DC-Link Control -- 4.2 Generation of Reference Current Source -- 5 Simulation Results -- 6 Conclusion -- References -- Comparative Analysis Between Single Diode and Double Diode Solar Topologies of Solar PV Cell -- 1 Introduction -- 2 Modeling of Single Diode Scheme -- 3 Modeling of Double Diode Scheme -- 4 Simulation and Comparative Analysis -- 5 Conclusion -- References -- Control of Three-Phase Grid-Connected Inverter Using dq Axis Theory -- 1 Introduction -- 2 Operation of 3-ɸ GCI -- 3 dq Axis Theory -- 3.1 AC to DC Transformation -- 3.2 DC to AC Transformation -- 4 Control Strategy -- 5 Simulation Result -- 6 Conclusion -- References. Active-Reactive Power Support with Optimal Allocation of DG and DSTATCOM in Distribution System Using Flower Pollination and Artificial Bee Colony Algorithm with Load Growth -- 1 Introduction -- 2 Problem Formulation -- 2.1 Load Flow Analysis -- 2.2 Objective Function (oF) -- 2.3 Investment Cost (IC) -- 2.4 Cost of Energy Saving (CE) -- 2.5 Annual Cost Saving (ACS) -- 3 Flower Pollination Algorithm (FPA) -- 4 Artificial Bee Colony (ABC) Algorithm -- 5 Results and Discussions -- 6 Conclusions -- References -- Analysis and Design Optimization of Six-Phase Induction Motor by Metaheuristic Methods -- 1 Introduction -- 2 Optimization Algorithms -- 2.1 Modified Flower Pollination Algorithm -- 2.2 Novel Bat Algorithm -- 2.3 Cuckoo Search Algorithm -- 3 Design Problem Formulation of Six-Phase Induction Motor -- 4 Objective Functions and Design Equations -- 4.1 Novel Bat Algorithm -- 4.2 Modified Flower Pollination Algorithm -- 4.3 Cuckoo Search Algorithm -- 5 Results and Discussions -- 5.1 Validation of Proposed Algorithm -- 6 Development of Simulink Model -- 7 Performance Analysis of the SPIM for Different Design Methods -- 8 Conclusions -- 9 List of Symbols Used -- References -- Implementation of Complete Vector Control for DFIG Based Wind Turbine -- 1 Introduction -- 2 Wind Turbine -- 3 Doubly Fed Induction Machine -- 4 Vector Control for Implemented DFIM -- 5 MATLAB Simulation -- 6 Results and Discussions -- 7 Conclusion -- References -- TLO Based OPF with FACTS Devices for DC Link Placement Problem -- 1 Introduction -- 2 Problem Statement with FACTS Devices -- 2.1 Representation of Decision Variables -- 3 Results and Discussions -- 4 Conclusion and Future Research -- References -- Performance Comparison Analysis of Energy Management Strategies for Hybrid Electric Vehicles -- 1 Introduction -- 2 System Architecture -- 3 Energy Management Strategies. 3.1 Classical PI Control Strategy -- 3.2 Optimization Based ECMS -- 3.3 RB Energy Management Strategy -- 4 Results and Discussion -- 4.1 Comparative Energy Contribution by Individual Power Source -- 4.2 Performance Comparison Among RB, PI and ECMS Strategy -- 5 Conclusion -- References -- Evaluative Study of Cascaded Multilevel Inverter Topologies -- 1 Introduction -- 2 Classical 11-Level CHB -- 3 Modulation Strategy for Classical CHB -- 4 Modulated 11-Level CHB -- 5 Comparative Assessment Between Classical and Modified CHB -- 6 Simulation Result -- 7 Conclusion -- References -- Low Speed Performance Improvement of Dual VSI Fed Direct Torque Controlled Five Phase Open-End Winding Induction Motor -- 1 Introduction -- 2 Mathematical Modelling of Dual VSI Fed Five Phase OEW Induction Motor -- 3 Proposed DTC Operation for Dual Inverter Configuration -- 4 Results and Discussion -- 4.1 Simulation Results -- 5 Conclusions -- References -- Self-balanced Symmetric Source Configuration of Nine Level Switched Capacitor-Based Grid Connected Inverter with LCL Filter -- 1 Introduction -- 2 Operation of Proposed Topology and Control Schemes -- 3 Comparative Analysis -- 4 Simulation Results -- 5 Conclusion -- References -- Priority-Based Charging of Electric Vehicles to Prevent Distribution Transformer Overloading -- 1 Introduction -- 2 System Modeling -- 2.1 Network Topology -- 2.2 Base (Non-EV) Load on the System -- 2.3 EV Charging Load -- 2.4 Load Flow Analysis -- 3 Priority-Based Charging -- 3.1 Motivation -- 3.2 Methodology -- 3.3 Calculation of Priority -- 4 Results and Analysis -- 5 Conclusion -- References -- Implementation of Three-Phase Hybrid Energy System Integrated with UPQC -- 1 Introduction -- 2 Literature Survey -- 3 System Design and Configuration -- 4 PV-UPQC Control -- 4.1 Shunt Compensator Control -- 4.2 Series Compensator Control. 5 Simulation Results. |
| Record Nr. | UNINA-9910743222303321 |
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Kumar Shailendra
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| Singapore : , : Springer, , [2022] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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