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Comparative physiology, natural animal models, and clinical medicine [[electronic resource] ] : insights into clinical medicine from animal adaptations / / Michael A. Singer
| Comparative physiology, natural animal models, and clinical medicine [[electronic resource] ] : insights into clinical medicine from animal adaptations / / Michael A. Singer |
| Autore | Singer Michael A (Michael Allan), <1940-> |
| Pubbl/distr/stampa | London, : Imperial College Press, c2007 |
| Descrizione fisica | 1 online resource (292 p.) |
| Disciplina |
616.0076
616.0273 |
| Soggetto topico |
Diseases - Animal models
Physiology, Comparative Laboratory animals |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-281-86755-1
9786611867553 1-86094-949-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Acknowledgements; Introduction; Chapter 1 Diabetes Mellitus; Introduction; Blood Glucose Values in Birds; Do Birds Suffer Adverse Consequences from a High Blood Glucose Concentration; Anatomic and Physiologic Design Features; Eye; Retinal nutrient supply; Retinal vascularization in mammals; Avian and mammalian retinal physiology and development; Diabetic retinopathy; Kidney; Kidney anatomy and function in birds and mammals; Diabetic nephropathy; (a) Renal glucose transporters; (b) Juxtaglomerular apparatus; Glycated hemoglobin; Concluding Remarks and Future Research; References
Chapter 2 Chronic Renal FailureIntroduction; Metabolic Rate and Renal Function; Nitrogen and Urea Metabolism and Protein Turnover; Nitrogen and urea metabolism; Urea transport proteins; Protein turnover; Alterations in urea and protein metabolism in chronic renal failure; Additional Aspects of Renal Failure; Natural Animal Model; Bear and Small Mammal Hibernators; Concluding Remarks and Future Directions; References; Chapter 3 Atherosclerotic Vascular Disease; Introduction; Atherosclerosis in Mammals; Biology of the Arterial System: Implications for the Genesis of Atherosclerosis in Mammals Genesis of Atherosclerotic LesionsNatural Animal Model: The Fish; Fish Coronary Circulation; Fish Coronary Artery Thickenings; Genesis of Fish Lesions; Biomechanical Factors in Fish; Dietary In.uences and Role of Cholesterol in Fish; Biology of the Vascular Smooth Muscle in Fish; Concluding Remarks: What Can We Learn From the Fish as a Natural Model?; References; Chapter 4 Disuse Osteoporosis and Disuse Muscle Atrophy; Disuse Osteoporosis; Bone biology; Parathyroid hormone (PTH); Vitamin D; Leptin; Mechanical stress; Disuse osteoporosis Natural animal model: American black bear (Ursus americanus)Bone homeostasis in the bear: research questions; Disuse Muscle Atrophy; Maintenance of muscle mass; Protein degradation: mechanisms; Animal models; Studies in humans and small mammal hibernators; Humans; Small mammal hibernators; Natural animal model: the American black bear; The bear: a perspective; References; Chapter 5 Ammonia Toxicity; Ammonia Tolerance and Metabolism; Ammonia tolerance; Ammonia metabolism; Brain Ammonia Metabolism; Glutamatergic Neurons; General considerations (Purves et al., 2004) Glutamate, a Neurotransmitter and the "Glutamate-Glutamine" CycleMechanism of Ammonia Neurotoxicity; Neuropathological effects; Effects on Brain Energy Metabolism; Effects on Glutamatergic Synapses; Ammonia and the Fish Central Nervous System; Role of glutamine; Glutamate; Brain energy metabolism; NMDA receptors; Summary; References; Chapter 6 Hypoxia/Ischemia; Cerebral Blood Flow: Its Regulation; Brain Energy Metabolism; Oxygen and Oxygen/Glucose Deprivation and the Brain; General features of neuronal response; Anoxia tolerant mammalian neurons; Neonatal brain; Dorsal vagal neurons Neonatal neurons |
| Record Nr. | UNINA-9910458113103321 |
Singer Michael A (Michael Allan), <1940->
|
||
| London, : Imperial College Press, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Comparative physiology, natural animal models, and clinical medicine [[electronic resource] ] : insights into clinical medicine from animal adaptations / / Michael A. Singer
| Comparative physiology, natural animal models, and clinical medicine [[electronic resource] ] : insights into clinical medicine from animal adaptations / / Michael A. Singer |
| Autore | Singer Michael A (Michael Allan), <1940-> |
| Pubbl/distr/stampa | London, : Imperial College Press, c2007 |
| Descrizione fisica | 1 online resource (292 p.) |
| Disciplina |
616.0076
616.0273 |
| Soggetto topico |
Diseases - Animal models
Physiology, Comparative Laboratory animals |
| ISBN |
1-281-86755-1
9786611867553 1-86094-949-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Acknowledgements; Introduction; Chapter 1 Diabetes Mellitus; Introduction; Blood Glucose Values in Birds; Do Birds Suffer Adverse Consequences from a High Blood Glucose Concentration; Anatomic and Physiologic Design Features; Eye; Retinal nutrient supply; Retinal vascularization in mammals; Avian and mammalian retinal physiology and development; Diabetic retinopathy; Kidney; Kidney anatomy and function in birds and mammals; Diabetic nephropathy; (a) Renal glucose transporters; (b) Juxtaglomerular apparatus; Glycated hemoglobin; Concluding Remarks and Future Research; References
Chapter 2 Chronic Renal FailureIntroduction; Metabolic Rate and Renal Function; Nitrogen and Urea Metabolism and Protein Turnover; Nitrogen and urea metabolism; Urea transport proteins; Protein turnover; Alterations in urea and protein metabolism in chronic renal failure; Additional Aspects of Renal Failure; Natural Animal Model; Bear and Small Mammal Hibernators; Concluding Remarks and Future Directions; References; Chapter 3 Atherosclerotic Vascular Disease; Introduction; Atherosclerosis in Mammals; Biology of the Arterial System: Implications for the Genesis of Atherosclerosis in Mammals Genesis of Atherosclerotic LesionsNatural Animal Model: The Fish; Fish Coronary Circulation; Fish Coronary Artery Thickenings; Genesis of Fish Lesions; Biomechanical Factors in Fish; Dietary In.uences and Role of Cholesterol in Fish; Biology of the Vascular Smooth Muscle in Fish; Concluding Remarks: What Can We Learn From the Fish as a Natural Model?; References; Chapter 4 Disuse Osteoporosis and Disuse Muscle Atrophy; Disuse Osteoporosis; Bone biology; Parathyroid hormone (PTH); Vitamin D; Leptin; Mechanical stress; Disuse osteoporosis Natural animal model: American black bear (Ursus americanus)Bone homeostasis in the bear: research questions; Disuse Muscle Atrophy; Maintenance of muscle mass; Protein degradation: mechanisms; Animal models; Studies in humans and small mammal hibernators; Humans; Small mammal hibernators; Natural animal model: the American black bear; The bear: a perspective; References; Chapter 5 Ammonia Toxicity; Ammonia Tolerance and Metabolism; Ammonia tolerance; Ammonia metabolism; Brain Ammonia Metabolism; Glutamatergic Neurons; General considerations (Purves et al., 2004) Glutamate, a Neurotransmitter and the "Glutamate-Glutamine" CycleMechanism of Ammonia Neurotoxicity; Neuropathological effects; Effects on Brain Energy Metabolism; Effects on Glutamatergic Synapses; Ammonia and the Fish Central Nervous System; Role of glutamine; Glutamate; Brain energy metabolism; NMDA receptors; Summary; References; Chapter 6 Hypoxia/Ischemia; Cerebral Blood Flow: Its Regulation; Brain Energy Metabolism; Oxygen and Oxygen/Glucose Deprivation and the Brain; General features of neuronal response; Anoxia tolerant mammalian neurons; Neonatal brain; Dorsal vagal neurons Neonatal neurons |
| Record Nr. | UNINA-9910784887003321 |
|
Singer Michael A (Michael Allan), <1940->
|
||
| London, : Imperial College Press, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Comparative physiology, natural animal models, and clinical medicine : insights into clinical medicine from animal adaptations / / Michael A. Singer
| Comparative physiology, natural animal models, and clinical medicine : insights into clinical medicine from animal adaptations / / Michael A. Singer |
| Autore | Singer Michael A (Michael Allan), <1940-> |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | London, : Imperial College Press, c2007 |
| Descrizione fisica | 1 online resource (292 p.) |
| Disciplina |
616.0076
616.0273 |
| Soggetto topico |
Diseases - Animal models
Physiology, Comparative Laboratory animals |
| ISBN |
1-281-86755-1
9786611867553 1-86094-949-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Acknowledgements; Introduction; Chapter 1 Diabetes Mellitus; Introduction; Blood Glucose Values in Birds; Do Birds Suffer Adverse Consequences from a High Blood Glucose Concentration; Anatomic and Physiologic Design Features; Eye; Retinal nutrient supply; Retinal vascularization in mammals; Avian and mammalian retinal physiology and development; Diabetic retinopathy; Kidney; Kidney anatomy and function in birds and mammals; Diabetic nephropathy; (a) Renal glucose transporters; (b) Juxtaglomerular apparatus; Glycated hemoglobin; Concluding Remarks and Future Research; References
Chapter 2 Chronic Renal FailureIntroduction; Metabolic Rate and Renal Function; Nitrogen and Urea Metabolism and Protein Turnover; Nitrogen and urea metabolism; Urea transport proteins; Protein turnover; Alterations in urea and protein metabolism in chronic renal failure; Additional Aspects of Renal Failure; Natural Animal Model; Bear and Small Mammal Hibernators; Concluding Remarks and Future Directions; References; Chapter 3 Atherosclerotic Vascular Disease; Introduction; Atherosclerosis in Mammals; Biology of the Arterial System: Implications for the Genesis of Atherosclerosis in Mammals Genesis of Atherosclerotic LesionsNatural Animal Model: The Fish; Fish Coronary Circulation; Fish Coronary Artery Thickenings; Genesis of Fish Lesions; Biomechanical Factors in Fish; Dietary In.uences and Role of Cholesterol in Fish; Biology of the Vascular Smooth Muscle in Fish; Concluding Remarks: What Can We Learn From the Fish as a Natural Model?; References; Chapter 4 Disuse Osteoporosis and Disuse Muscle Atrophy; Disuse Osteoporosis; Bone biology; Parathyroid hormone (PTH); Vitamin D; Leptin; Mechanical stress; Disuse osteoporosis Natural animal model: American black bear (Ursus americanus)Bone homeostasis in the bear: research questions; Disuse Muscle Atrophy; Maintenance of muscle mass; Protein degradation: mechanisms; Animal models; Studies in humans and small mammal hibernators; Humans; Small mammal hibernators; Natural animal model: the American black bear; The bear: a perspective; References; Chapter 5 Ammonia Toxicity; Ammonia Tolerance and Metabolism; Ammonia tolerance; Ammonia metabolism; Brain Ammonia Metabolism; Glutamatergic Neurons; General considerations (Purves et al., 2004) Glutamate, a Neurotransmitter and the "Glutamate-Glutamine" CycleMechanism of Ammonia Neurotoxicity; Neuropathological effects; Effects on Brain Energy Metabolism; Effects on Glutamatergic Synapses; Ammonia and the Fish Central Nervous System; Role of glutamine; Glutamate; Brain energy metabolism; NMDA receptors; Summary; References; Chapter 6 Hypoxia/Ischemia; Cerebral Blood Flow: Its Regulation; Brain Energy Metabolism; Oxygen and Oxygen/Glucose Deprivation and the Brain; General features of neuronal response; Anoxia tolerant mammalian neurons; Neonatal brain; Dorsal vagal neurons Neonatal neurons |
| Record Nr. | UNINA-9910819948803321 |
|
Singer Michael A (Michael Allan), <1940->
|
||
| London, : Imperial College Press, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||