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Magic bullets to conquer malaria [[electronic resource] ] : from quinine to qinghaosu / / Irwin W. Sherman
| Magic bullets to conquer malaria [[electronic resource] ] : from quinine to qinghaosu / / Irwin W. Sherman |
| Autore | Sherman Irwin W |
| Pubbl/distr/stampa | Washington, DC, : ASM Press, c2011 |
| Descrizione fisica | 1 online resource (314 p.) |
| Disciplina |
362.196/9362
616.936206 |
| Soggetto topico |
Antimalarials - History
Malaria - Treatment - History |
| ISBN |
1-119-73929-2
1-68367-099-X 1-283-03447-6 9786613034472 1-55581-688-6 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Contents; Preface; 1 From Breathing Bad Air to Biting Beasts; 2 Myth to Medicine: Quinine; 3 Synthetic Dyes to Drugs: Atabrine and Chloroquine; 4 Antimicrobials to Antimalarials: Prontosil, Pyrimethamine, Proguanil, and Atovaquone; 5 To Destroy Liver Stages: Primaquine and Tafenoquine; 6 Quinine to Mefloquine; 7 Reversal of Fortune; 8 Sweet Wormwood of Success: Qinghaosu; 9 Antibiotics and the Apicoplast; 10 A Possible Dream: Control by Blocking Transmission; 11 The Dream of Eradication; 12 A Reasonable Dream; References; Index |
| Record Nr. | UNINA-9910574099103321 |
Sherman Irwin W
|
||
| Washington, DC, : ASM Press, c2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Magic bullets to conquer malaria [[electronic resource] ] : from quinine to qinghaosu / / Irwin W. Sherman
| Magic bullets to conquer malaria [[electronic resource] ] : from quinine to qinghaosu / / Irwin W. Sherman |
| Autore | Sherman Irwin W |
| Pubbl/distr/stampa | Washington, DC, : ASM Press, c2011 |
| Descrizione fisica | 1 online resource (314 p.) |
| Disciplina |
362.196/9362
616.936206 |
| Soggetto topico |
Antimalarials - History
Malaria - Treatment - History |
| ISBN |
1-119-73929-2
1-68367-099-X 1-283-03447-6 9786613034472 1-55581-688-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Contents; Preface; 1 From Breathing Bad Air to Biting Beasts; 2 Myth to Medicine: Quinine; 3 Synthetic Dyes to Drugs: Atabrine and Chloroquine; 4 Antimicrobials to Antimalarials: Prontosil, Pyrimethamine, Proguanil, and Atovaquone; 5 To Destroy Liver Stages: Primaquine and Tafenoquine; 6 Quinine to Mefloquine; 7 Reversal of Fortune; 8 Sweet Wormwood of Success: Qinghaosu; 9 Antibiotics and the Apicoplast; 10 A Possible Dream: Control by Blocking Transmission; 11 The Dream of Eradication; 12 A Reasonable Dream; References; Index |
| Record Nr. | UNINA-9910830701903321 |
|
Sherman Irwin W
|
||
| Washington, DC, : ASM Press, c2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Magic bullets to conquer malaria [[electronic resource] ] : from quinine to qinghaosu / / Irwin W. Sherman
| Magic bullets to conquer malaria [[electronic resource] ] : from quinine to qinghaosu / / Irwin W. Sherman |
| Autore | Sherman Irwin W |
| Pubbl/distr/stampa | Washington, DC, : ASM Press, c2011 |
| Descrizione fisica | 1 online resource (314 p.) |
| Disciplina |
362.196/9362
616.936206 |
| Soggetto topico |
Antimalarials - History
Malaria - Treatment - History |
| ISBN |
1-119-73929-2
1-68367-099-X 1-283-03447-6 9786613034472 1-55581-688-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Contents; Preface; 1 From Breathing Bad Air to Biting Beasts; 2 Myth to Medicine: Quinine; 3 Synthetic Dyes to Drugs: Atabrine and Chloroquine; 4 Antimicrobials to Antimalarials: Prontosil, Pyrimethamine, Proguanil, and Atovaquone; 5 To Destroy Liver Stages: Primaquine and Tafenoquine; 6 Quinine to Mefloquine; 7 Reversal of Fortune; 8 Sweet Wormwood of Success: Qinghaosu; 9 Antibiotics and the Apicoplast; 10 A Possible Dream: Control by Blocking Transmission; 11 The Dream of Eradication; 12 A Reasonable Dream; References; Index |
| Record Nr. | UNINA-9910877544803321 |
|
Sherman Irwin W
|
||
| Washington, DC, : ASM Press, c2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Malaria Genome Projects [[electronic resource] ] : promise, progress, and prospects / / Irwin W. Sherman
| Malaria Genome Projects [[electronic resource] ] : promise, progress, and prospects / / Irwin W. Sherman |
| Autore | Sherman Irwin W |
| Pubbl/distr/stampa | London, : Imperial College Press |
| Descrizione fisica | 1 online resource (389 p.) |
| Disciplina | 616.9362 |
| Soggetto topico |
Malaria - Molecular aspects
Plasmodium falciparum - Genome mapping |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-283-59355-6
9786613906007 1-84816-904-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Dedication; Contents; Preface; Chapter 1. Introduction; Plasmodium discovered; Plasmodium transmitted; Plasmodium in hiding; Chapter 2. Respice: Before the Genome Project; Chapter 3. The Nature of Plasmodium falciparum and its Genome; A home for the genome; Location, location, location; The malaria genome capers; Chapter 4. Chipping Away at the Genome; Turning "on," turning "off"; Evasion; Chapter 5. The Importance of Import; Chapter 6. Remodeling the Genome's Home; Chapter 7. Getting on the Inside; Chapter 8. The Great Escape; Chapter 9. The Neglected Malaria, Plasmodium vivax; Resistance
Secrets hidden in the genomeChapter 10. The Anopheles Genome and Transmission Control; Making mosquitoes immune; Making mosquitoes insecticide resistant; Replacement and/or reduction; Chapter 11. The Monkey's Tale; Chapter 12. A Not So Sweet Solution; Isoenzymes, the Achilles' heels of Plasmodium; Tackling the Krebs "cycle"; Chapter 13. To Search and Find; Rapid diagnostic tests; Nucleic acid-based tests; Loop-mediated isothermal amplification; Chapter 14. The Elusive Vaccines; Antigens before the genome; Two blood-stage vaccine candidates; The road to merozoite surface protein The road to apical membrane antigen 1A failed promise, SPf66; Transmission-blocking vaccines; The sporozoite vaccine revisited; Development of the pre-blood-stage vaccine, RTS, S; Back to the future; Learning from the liver; Vaccine approaches before sequencing the genome; Vaccine approaches after sequencing the genome; Chapter 15. New Medicines, Old Problems; The old problem of resistance; Chloro quine; Resistance to anti-folate drugs; Mefloquine and multidrug resistance; The fall of mefloquine; Atovaquone; Artemisia to artemisinins; Chapter 16. Prospice: Looking to the Future; References Index |
| Record Nr. | UNINA-9910464968203321 |
|
Sherman Irwin W
|
||
| London, : Imperial College Press | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Malaria Genome Projects [[electronic resource] ] : promise, progress, and prospects / / Irwin W. Sherman
| Malaria Genome Projects [[electronic resource] ] : promise, progress, and prospects / / Irwin W. Sherman |
| Autore | Sherman Irwin W |
| Pubbl/distr/stampa | London, : Imperial College Press |
| Descrizione fisica | 1 online resource (389 p.) |
| Disciplina | 616.9362 |
| Soggetto topico |
Malaria - Molecular aspects
Plasmodium falciparum - Genome mapping |
| ISBN |
1-283-59355-6
9786613906007 1-84816-904-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Dedication; Contents; Preface; Chapter 1. Introduction; Plasmodium discovered; Plasmodium transmitted; Plasmodium in hiding; Chapter 2. Respice: Before the Genome Project; Chapter 3. The Nature of Plasmodium falciparum and its Genome; A home for the genome; Location, location, location; The malaria genome capers; Chapter 4. Chipping Away at the Genome; Turning "on," turning "off"; Evasion; Chapter 5. The Importance of Import; Chapter 6. Remodeling the Genome's Home; Chapter 7. Getting on the Inside; Chapter 8. The Great Escape; Chapter 9. The Neglected Malaria, Plasmodium vivax; Resistance
Secrets hidden in the genomeChapter 10. The Anopheles Genome and Transmission Control; Making mosquitoes immune; Making mosquitoes insecticide resistant; Replacement and/or reduction; Chapter 11. The Monkey's Tale; Chapter 12. A Not So Sweet Solution; Isoenzymes, the Achilles' heels of Plasmodium; Tackling the Krebs "cycle"; Chapter 13. To Search and Find; Rapid diagnostic tests; Nucleic acid-based tests; Loop-mediated isothermal amplification; Chapter 14. The Elusive Vaccines; Antigens before the genome; Two blood-stage vaccine candidates; The road to merozoite surface protein The road to apical membrane antigen 1A failed promise, SPf66; Transmission-blocking vaccines; The sporozoite vaccine revisited; Development of the pre-blood-stage vaccine, RTS, S; Back to the future; Learning from the liver; Vaccine approaches before sequencing the genome; Vaccine approaches after sequencing the genome; Chapter 15. New Medicines, Old Problems; The old problem of resistance; Chloro quine; Resistance to anti-folate drugs; Mefloquine and multidrug resistance; The fall of mefloquine; Atovaquone; Artemisia to artemisinins; Chapter 16. Prospice: Looking to the Future; References Index |
| Record Nr. | UNINA-9910792094103321 |
|
Sherman Irwin W
|
||
| London, : Imperial College Press | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Malaria Genome Projects : promise, progress, and prospects / / Irwin W. Sherman
| Malaria Genome Projects : promise, progress, and prospects / / Irwin W. Sherman |
| Autore | Sherman Irwin W |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | London, : Imperial College Press |
| Descrizione fisica | 1 online resource (389 p.) |
| Disciplina | 616.9362 |
| Soggetto topico |
Malaria - Molecular aspects
Plasmodium falciparum - Genome mapping |
| ISBN |
1-283-59355-6
9786613906007 1-84816-904-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Dedication; Contents; Preface; Chapter 1. Introduction; Plasmodium discovered; Plasmodium transmitted; Plasmodium in hiding; Chapter 2. Respice: Before the Genome Project; Chapter 3. The Nature of Plasmodium falciparum and its Genome; A home for the genome; Location, location, location; The malaria genome capers; Chapter 4. Chipping Away at the Genome; Turning "on," turning "off"; Evasion; Chapter 5. The Importance of Import; Chapter 6. Remodeling the Genome's Home; Chapter 7. Getting on the Inside; Chapter 8. The Great Escape; Chapter 9. The Neglected Malaria, Plasmodium vivax; Resistance
Secrets hidden in the genomeChapter 10. The Anopheles Genome and Transmission Control; Making mosquitoes immune; Making mosquitoes insecticide resistant; Replacement and/or reduction; Chapter 11. The Monkey's Tale; Chapter 12. A Not So Sweet Solution; Isoenzymes, the Achilles' heels of Plasmodium; Tackling the Krebs "cycle"; Chapter 13. To Search and Find; Rapid diagnostic tests; Nucleic acid-based tests; Loop-mediated isothermal amplification; Chapter 14. The Elusive Vaccines; Antigens before the genome; Two blood-stage vaccine candidates; The road to merozoite surface protein The road to apical membrane antigen 1A failed promise, SPf66; Transmission-blocking vaccines; The sporozoite vaccine revisited; Development of the pre-blood-stage vaccine, RTS, S; Back to the future; Learning from the liver; Vaccine approaches before sequencing the genome; Vaccine approaches after sequencing the genome; Chapter 15. New Medicines, Old Problems; The old problem of resistance; Chloro quine; Resistance to anti-folate drugs; Mefloquine and multidrug resistance; The fall of mefloquine; Atovaquone; Artemisia to artemisinins; Chapter 16. Prospice: Looking to the Future; References Index |
| Record Nr. | UNINA-9910819000703321 |
|
Sherman Irwin W
|
||
| London, : Imperial College Press | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||