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Immunology : an introductory textbook / / edited by Anil K. Sharma
| Immunology : an introductory textbook / / edited by Anil K. Sharma |
| Pubbl/distr/stampa | Singapore : , : Pan Stanford Publishing, , 2019 |
| Descrizione fisica | 1 online resource (261 pages) |
| Disciplina | 616.079072 |
| Soggetto topico |
Immunology - Research
Immunology - Technique |
| ISBN |
1-351-36694-7
1-351-36695-5 1-315-15063-8 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Half Title; Title Page; Copyright Page; Table of Contents; Preface; 1: Introduction to lmmunology; 1.1 Historical Attributes; 1.2 lmmunological Responses and Effectors; 1.2.1 lnnate and Adaptive lmmunity; 1.2.1.1 lnnate immunity; 1.2.1.2 Adaptive immunity; 1.3 Summary; 2: lmmunity; 2.1 Basic Concept of lmmunity; 2.2 Historical Background of Immune Responses; 2.3 Cell-Mediated Immune Responses; 2.4 Processing of Endogenous Antigens: Cytosolic Pathway; 2.5 Processing of Endogenous Antigens: Endocytic Pathway; 2.6 Humoral Immunity; 2.7 Activation of B-Cells
2.8 Humoral Response to T-Dependent Antigens2.9 Humoral Response to T-lndependent Antigens; 3: Proteins of the Immune System; 3.1 Antimicrobial Peptide; 3.2 Pattern Recognition Receptor; 3.3 Toll-Like Receptors; 3.4 NOD Protein; 3.5 Acute Phase Proteins; 3.6 Interferon; 3.7 Complement System; 3.7.1 Function of Complement System; 3.7.2 Complement Nomenclature; 3.8 Activation of Complement Pathways; 3.9 Classical Pathway of the Complement System; 3.10 Lectin Pathway; 3.11 Alternative Pathway; 3.12 Small Fragments of the Complement Protein Initiates Local Inflammatory Response 3.13 Membrane Attack Complex (MAC) or Lytic Pathway3.14 Regulation of Complement Protein; 3.15 Summary; 4: Major Histocompatibility Complex (MHC): Recent Trends and Relevance from lmmunological Perspective; 4.1 Introduction; 4.2 Nomenclature of HLA Antigens; 4.3 Frequency of Different HLA Alleles; 4.4 Molecular and Genetics Basis of MHC Polymorphisms; 4.4.1 Inheritance; 4.4.2 Expression; 4.5 MHC Molecules: Structure and Genetics; 4.5.1 MHC Class I vs. MHC Class Il; 4.5.1.1 MHC Class I; 4.5.1.2 MHC Class Il; 4.6 Role of MHC in Immune Response; 4.6.1 The Mixed Lymphocyte Reaction 4.6.2 Antigen Processing and Presentation4.6.3 Sorne Points about MHC Class I and Class Il /TCR; 4.7 Antigen Processing and Presentation; 4.8 Langerhans Cells as APC; 4.9 Antigen Processing and Presentation by Class Il (Exogenous/Endocytic) Pathway; 4.10 Antigen Processing and Presentation by Class I (Endogenous/Cytosolic) Pathway; 4.11 Significance of MHC-Peptide Presentation; 4.12 Clonal Selection of T-cells; 4.13 Generation of Cytotoxic T-Cells; 4.14 Immune Response Genes; 4.15 Complement Factor Genes; 4.16 Nonimmunologic Functions of MHC Genes 4.17 Disease and the Major Histocompatibility Complex5: Immune System of the Brain; 5.1 Introduction; 5.2 Microglia; 5.3 Astrocytes; 5.4 Toll-Like Receptors; 5.5 Pro-lnflammatory Cytokines; 5.6 Summary; 6: An Overview of lmmunodeficiency Disorders; 6.1 Introduction; 6.2 Primary lmmunodeficiency Diseases; 6.3 Classification of Primary lmmunodeficiency; 6.3.1 Severe Combined lmmunodeficiency; 6.3.1.1 X-linked recessive severe combined immunodeficiency; 6.3.1.2 Adenosine deaminase deficiency; 6.3.2 Well-Defined Syndromes with lmmunodeficiency |
| Record Nr. | UNINA-9910793456503321 |
| Singapore : , : Pan Stanford Publishing, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Immunology : an introductory textbook / / edited by Anil K. Sharma
| Immunology : an introductory textbook / / edited by Anil K. Sharma |
| Pubbl/distr/stampa | Singapore : , : Pan Stanford Publishing, , 2019 |
| Descrizione fisica | 1 online resource (261 pages) |
| Disciplina | 616.079072 |
| Soggetto topico |
Immunology - Research
Immunology - Technique |
| ISBN |
1-351-36694-7
1-351-36695-5 1-315-15063-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Half Title; Title Page; Copyright Page; Table of Contents; Preface; 1: Introduction to lmmunology; 1.1 Historical Attributes; 1.2 lmmunological Responses and Effectors; 1.2.1 lnnate and Adaptive lmmunity; 1.2.1.1 lnnate immunity; 1.2.1.2 Adaptive immunity; 1.3 Summary; 2: lmmunity; 2.1 Basic Concept of lmmunity; 2.2 Historical Background of Immune Responses; 2.3 Cell-Mediated Immune Responses; 2.4 Processing of Endogenous Antigens: Cytosolic Pathway; 2.5 Processing of Endogenous Antigens: Endocytic Pathway; 2.6 Humoral Immunity; 2.7 Activation of B-Cells
2.8 Humoral Response to T-Dependent Antigens2.9 Humoral Response to T-lndependent Antigens; 3: Proteins of the Immune System; 3.1 Antimicrobial Peptide; 3.2 Pattern Recognition Receptor; 3.3 Toll-Like Receptors; 3.4 NOD Protein; 3.5 Acute Phase Proteins; 3.6 Interferon; 3.7 Complement System; 3.7.1 Function of Complement System; 3.7.2 Complement Nomenclature; 3.8 Activation of Complement Pathways; 3.9 Classical Pathway of the Complement System; 3.10 Lectin Pathway; 3.11 Alternative Pathway; 3.12 Small Fragments of the Complement Protein Initiates Local Inflammatory Response 3.13 Membrane Attack Complex (MAC) or Lytic Pathway3.14 Regulation of Complement Protein; 3.15 Summary; 4: Major Histocompatibility Complex (MHC): Recent Trends and Relevance from lmmunological Perspective; 4.1 Introduction; 4.2 Nomenclature of HLA Antigens; 4.3 Frequency of Different HLA Alleles; 4.4 Molecular and Genetics Basis of MHC Polymorphisms; 4.4.1 Inheritance; 4.4.2 Expression; 4.5 MHC Molecules: Structure and Genetics; 4.5.1 MHC Class I vs. MHC Class Il; 4.5.1.1 MHC Class I; 4.5.1.2 MHC Class Il; 4.6 Role of MHC in Immune Response; 4.6.1 The Mixed Lymphocyte Reaction 4.6.2 Antigen Processing and Presentation4.6.3 Sorne Points about MHC Class I and Class Il /TCR; 4.7 Antigen Processing and Presentation; 4.8 Langerhans Cells as APC; 4.9 Antigen Processing and Presentation by Class Il (Exogenous/Endocytic) Pathway; 4.10 Antigen Processing and Presentation by Class I (Endogenous/Cytosolic) Pathway; 4.11 Significance of MHC-Peptide Presentation; 4.12 Clonal Selection of T-cells; 4.13 Generation of Cytotoxic T-Cells; 4.14 Immune Response Genes; 4.15 Complement Factor Genes; 4.16 Nonimmunologic Functions of MHC Genes 4.17 Disease and the Major Histocompatibility Complex5: Immune System of the Brain; 5.1 Introduction; 5.2 Microglia; 5.3 Astrocytes; 5.4 Toll-Like Receptors; 5.5 Pro-lnflammatory Cytokines; 5.6 Summary; 6: An Overview of lmmunodeficiency Disorders; 6.1 Introduction; 6.2 Primary lmmunodeficiency Diseases; 6.3 Classification of Primary lmmunodeficiency; 6.3.1 Severe Combined lmmunodeficiency; 6.3.1.1 X-linked recessive severe combined immunodeficiency; 6.3.1.2 Adenosine deaminase deficiency; 6.3.2 Well-Defined Syndromes with lmmunodeficiency |
| Record Nr. | UNINA-9910820026503321 |
| Singapore : , : Pan Stanford Publishing, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Nutraceuticals and dietary supplements : applications in health improvement and disease management / / edited by Raj K. Keservani, MPharm, Anil K. Sharma, PhD, MPharm, Rajesh K. Kesharwani, PhD
| Nutraceuticals and dietary supplements : applications in health improvement and disease management / / edited by Raj K. Keservani, MPharm, Anil K. Sharma, PhD, MPharm, Rajesh K. Kesharwani, PhD |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Burlington, ON, Canada ; ; Palm Bay, Florida, USA : , : Apple Academic Press, , 2021 |
| Descrizione fisica | 1 online resource (xxi, 319 pages) : illustrations, maps |
| Disciplina | 613.2 |
| Soggetto topico |
Dietary supplements - Therapeutic use
Functional food - Therapeutic use |
| ISBN |
1-000-73090-5
0-367-82151-6 1-000-73120-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cover -- Half Title -- Title Page -- Copyright Page -- About the Editors -- Contents -- Contributors -- Abbreviations -- Preface -- PART I: Preamble of Nutraceuticals and Formulations -- 1. Functional Foods -- 2. Nutraceutical Bioactives -- 3. Introduction to Nutraceuticals and Dietary Supplements -- 4. Herbs in Health Management -- 5. Starch-Based Nanocarriers of Nutraceuticals: Synthesis and Applications -- PART II: Role of Nutraceuticals in Cancer Treatment -- 6. Study of Nutraceuticals in Cancer Treatment: An In Silico Approach -- 7. Nutraceuticals in Cancer Therapy -- PART III: Nutraceuticals and Mental Illness -- 8. Exploration of Nanonutraceuticals in Neurodegenerative Diseases -- 9. Preclinical Perspectives of Mechanisms Underlying the Neuroprotective Effects of Selected Phyto-Constituents in Alzheimer's Disease -- PART IV: Specialized Applications of Nutraceuticals -- 10. Science Behind Maca: A Traditional Crop from the Central Andes -- 11. Nutraceutical Intervention for Treatment of Alcoholism and Drinking Problems -- 12. Beta Cells and Diabetes -- Index. |
| Record Nr. | UNINA-9910860850403321 |
| Burlington, ON, Canada ; ; Palm Bay, Florida, USA : , : Apple Academic Press, , 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Nutraceuticals and Functional Foods in Immunomodulators / / Rajesh K. Kesharwani, Raj K. Keservani, and Anil K. Sharma, editors
| Nutraceuticals and Functional Foods in Immunomodulators / / Rajesh K. Kesharwani, Raj K. Keservani, and Anil K. Sharma, editors |
| Pubbl/distr/stampa | Singapore : , : Springer, , [2022] |
| Descrizione fisica | 1 online resource (351 pages) |
| Disciplina | 571.9645 |
| Soggetto topico | Immunological adjuvants |
| ISBN | 981-19-2507-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Part I: Nutraceuticals and Functional Foods -- Part II: Micronutrients and Macronutrients -- Contents -- About the Editors -- Part I: Nutraceuticals and Functional Foods -- Chapter 1: Nanotechnology-Based Bacterial Immunotherapy -- 1.1 Introduction -- 1.2 Role of the Immune System in Cancer -- 1.3 Role of Bacteria in Immunotherapy -- 1.3.1 Effect of Bacteria on Myeloid Cell -- 1.3.1.1 Tumor-Associated Macrophages -- 1.3.1.2 Dendritic Cells and TANs -- 1.3.1.3 Effect of Bacteria on Tumor-Associated Lymphoid Cells -- Natural Killer Cell -- 1.3.2 CD4+ and CD8+ T Cells -- 1.3.3 Gamma-Delta (γδ) T Cells -- 1.3.4 Effect of Bacteria on Immunosuppressor Cells -- 1.3.4.1 Myeloid-Derived Suppressor Cells -- 1.4 Regulatory T Cells (Tregs) -- 1.5 Nanotechnology in Immunotherapy -- 1.5.1 Nanoparticle-Based Bacterial Immunotherapy -- 1.5.2 Nano-vaccine -- 1.5.3 Nanoparticulate System for Cancer Therapy -- 1.5.4 Thermotherapy -- 1.5.5 Radiotherapy and Diagnostic Purpose -- 1.6 Challenges and Opportunities for Nanotechnology-Based Immunotherapy -- 1.7 Advantage and Disadvantage -- 1.8 Conclusion -- References -- Chapter 2: Immunomodulatory Properties of Nutraceuticals and Functional Foods -- 2.1 Introduction -- 2.2 The Immune System -- 2.2.1 Hematopoiesis and the Immune System -- 2.2.2 The Immune System in Disease -- 2.2.3 Nutrition and Immunity -- 2.2.4 Immunosenescence and Nutrition -- 2.3 Immunomodulatory Response of Polyphenolic Compounds -- 2.3.1 Innate and Adaptive Immunity Regulated by Polyphenolic Compounds -- 2.3.2 Overview of Immune Responses in Human Studies -- 2.4 Immunomodulatory Effect of Vitamins -- 2.4.1 Immunomodulatory Properties of Liposoluble Vitamins -- 2.4.1.1 Vitamin A -- 2.4.1.2 Vitamin D -- 2.4.1.3 Vitamin E -- 2.4.2 Immunomodulatory Properties of Water-Soluble Vitamins -- 2.5 Immunomodulatory Response of Probiotics.
2.5.1 Gut Integrity-Promoting Activities -- 2.5.2 Direct Stimulation of Innate and Adaptive Immune Cells -- 2.5.3 Production of Microbial Metabolites and Substrates -- 2.5.4 In Situ Immunoenhancing Response of Probiotics by Fermented Foods -- 2.5.5 Live Biotherapeutic Products as Immune Probiotics -- 2.6 Immunomodulatory Response of Prebiotics -- 2.6.1 Immunostimulating Response of Prebiotics -- 2.6.1.1 Fructans -- 2.6.1.2 Pectin -- 2.6.1.3 Resistant Starch -- 2.7 Immunomodulatory Response of Bioactive Peptides -- 2.7.1 Immunomodulatory Peptides from Animal Foods -- 2.7.2 Immunomodulatory Peptides from Vegetable Foods -- 2.8 Perspectives -- References -- Chapter 3: Immunoregulatory Bioactive Phytoconstituents: Recent Trends and Future Challenges -- 3.1 Immunomodulators -- 3.2 Immunomodulatory Phytochemicals -- 3.3 Isolated Phytochemicals as Immunoregulators -- 3.3.1 Resveratrol -- 3.3.2 Epigallocatechin Gallate -- 3.3.3 Gingerol -- 3.3.4 Quercetin -- 3.3.5 Curcumin -- 3.3.6 Genistein and Daidezin -- 3.4 Concluding Remarks -- References -- Chapter 4: Effect of Plant-Derived Immunomodulators on the Immune System -- 4.1 Introduction -- 4.2 Immunomodulators -- 4.2.1 Natural Immunomodulators -- 4.2.2 Plant-Derived Immunomodulators -- 4.2.3 Physiochemical Properties of Quercetin -- 4.3 Bioavailability of Quercetin -- 4.4 Biological Functions of Quercetin -- 4.5 Mechanism of Action of Quercetin -- 4.6 Conclusions -- References -- Chapter 5: Polyphenols and Its Effect on the Immune System -- 5.1 Introduction -- 5.2 Structure and Function of Polyphenols -- 5.3 Immunomodulatory Mechanism of Polyphenols -- 5.4 Polyphenol´s Regulatory Effects on Different Immune Responses -- 5.4.1 Polyphenol and Insulin Resistance -- 5.4.2 Polyphenols and Inflammatory Neurological Diseases -- 5.4.3 Polyphenols and Allergic Diseases -- 5.4.4 Polyphenol and Tumor. 5.5 Different Types of Polyphenolic Compound and Their Effect on the Immune System -- 5.5.1 Quercetin -- 5.5.2 Resveratrol -- 5.5.3 Punicalagin -- 5.5.4 Apigenin -- 5.5.5 Genistein -- 5.5.6 Chrysin -- 5.5.7 Curcumin -- 5.5.8 Epigallocatechin Gallate (EGCG) -- 5.5.9 Phenolic Acid -- 5.6 Cross Talk -- 5.7 Conclusion -- References -- Chapter 6: Mineral Nutraceuticals and Immunity Enhancement -- 6.1 Introduction -- 6.2 Overview of Nutraceutical and Its Classification -- 6.3 Role of Various Minerals as a Nutraceutical -- 6.3.1 Zinc -- 6.3.2 Selenium -- 6.3.3 Copper -- 6.3.4 Magnesium -- 6.3.5 Iodine -- 6.3.6 Iron -- 6.3.7 Manganese -- 6.4 Immune System and Effect of Nutrition -- 6.5 Effects of Nutrition on the Immune System -- 6.6 Nutrients and Food Components for Modulation of Immunity -- 6.6.1 Vitamin D -- 6.6.2 Vitamin E -- 6.6.3 Fish Oil -- 6.6.4 Probiotics -- 6.6.5 Green Tea -- 6.6.6 Beta-Glucans -- 6.6.7 Polyphenols -- 6.6.8 Dietary Supplements -- 6.7 Discussion and Future Scope -- 6.7.1 Future Scope -- 6.8 Conclusion -- References -- Chapter 7: Nutraceuticals as Disease Preventive Food and Immunity Boosters -- 7.1 Introduction -- 7.1.1 Advantages -- 7.1.2 Emerging Trends in Nutraceuticals -- 7.1.3 Nutraceutical -- 7.2 Classification of Nutraceuticals -- 7.2.1 Nutraceuticals Based on Food Availability -- 7.2.2 Classification Based on Mechanism of Action -- 7.2.3 Classification Based on Chemical Nature -- 7.3 Categorizing Nutraceuticals -- 7.3.1 Dietary Fiber -- 7.3.2 Probiotics -- 7.3.3 Prebiotics -- 7.3.4 Polyunsaturated Fatty Acids (PUFA) -- 7.3.5 Antioxidant Vitamins -- 7.3.6 Polyphenols -- 7.3.7 Spices -- 7.4 Health Benefits (Chauhan et al. 2013 -- Baradaran et al. 2013) -- 7.5 Role of Nutraceuticals -- 7.5.1 Role of Bacterial Nutraceuticals -- 7.5.2 Antioxidants in Disease Prevention -- 7.5.3 Phytochemicals as Potential Nutraceuticals. 7.5.4 Polyunsaturated Fatty Acids as Nutraceuticals -- 7.6 Nutraceuticals in Diseases -- 7.6.1 Diabetes -- 7.6.2 Cardiovascular Diseases -- 7.6.3 Cancer -- 7.6.4 Obesity -- 7.6.5 Osteoarthritis -- 7.6.6 Alzheimer´s Disease -- 7.6.7 Parkinson´s Disease -- 7.6.8 Allergy -- 7.6.9 Oral Diseases -- 7.6.10 Eye Disorders -- 7.6.11 Migraine -- 7.6.12 Stress Management -- 7.6.13 Prolonging Life Span -- 7.6.14 Oral Health -- 7.6.15 Bone Health -- 7.7 Functional Foods -- 7.8 Significance of Synergic Foods -- 7.8.1 Synergistic Foods as Immune Boosters -- 7.8.2 Synergistic Foods to Prevent Infections -- 7.8.3 Synergistic Foods to Increase Bioavailability of Nutrients -- 7.8.4 Synergistic Foods to Reduce Chronic Diseases -- 7.8.5 Cardiovascular Diseases -- 7.8.6 Diabetes Mellitus -- 7.8.7 Cancer -- 7.8.8 Synergic Foods to Improve Mental and Reproductive Health -- 7.9 Current and Future Development of Nutraceuticals -- 7.10 Some Marketed Products Available as Nutraceuticals (Chaturvedi et al. 2011 -- Sarin et al. 2012 -- Pandey et al. 2010). -- 7.11 Conclusion -- References -- Part II: Micronutrients and Macronutrients -- Chapter 8: Current and Future Prospects of Flavonoids for Human Immune System -- 8.1 Introduction -- 8.2 Use of Flavonoids and Their Immunomodulatory Effects -- 8.2.1 Effect of Flavonoids on Cells of Innate Immune System -- 8.2.2 Effect of Flavonoids on Cells of Adaptive Immune System -- 8.2.3 Flavonoids as Radical Scavengers -- 8.2.4 Flavonoids and Their Anticancer Activity -- 8.2.5 Effect of Flavonoids on Various Neurodegenerative Diseases -- 8.2.6 Flavonoid Participation in Cognition and Signaling Pathway -- 8.2.7 Role of Flavonoids in Apoptosis -- 8.2.8 Multidimensional Activity of Flavonoids -- 8.2.9 Flavonoids and COVID-19 -- 8.3 Flavonoids: Futuristic Approach -- References -- Chapter 9: Resveratrol and Immunomodulation -- 9.1 Introduction. 9.2 Structure and Characteristics of Resveratrol -- 9.3 Sources/Production and Applications in Health -- 9.4 Immunomodulatory Role of Resveratrol in Various Pathologies -- 9.4.1 Antioxidant Activity -- 9.4.2 Anticancer Effect -- 9.4.3 Anti-inflammatory Activity -- 9.4.4 Antihypertensive Activity -- 9.4.5 Antiviral Effect -- 9.4.6 Resveratrol Effect in Metabolic Diseases -- 9.4.7 Resveratrol Effect in Autoimmune Diseases -- 9.4.8 Resveratrol Effect in Degenerative Diseases -- 9.5 Bioavailability and Metabolism of Resveratrol -- 9.6 Therapy Resveratrol Carriers -- 9.7 Conclusions -- References -- Chapter 10: Immunomodulation Impact of Curcumin and Its Derivative as a Natural Ingredient -- 10.1 Introduction -- 10.2 Immunomodulation -- 10.3 Chemical Composition of Turmeric -- 10.3.1 Curcumin and the Curcuminoids: Structure-Activity Relationships and Synthetic Analogs -- 10.4 Immunomodulatory Effect -- 10.5 Immunomodulation Properties of Curcuma Derivatives -- 10.5.1 Curcuma Longa -- 10.5.1.1 In Vitro Immunomodulating Effect of C. longa -- 10.5.1.2 In Vivo Immunomodulating Effect of C. longa -- 10.5.2 Curcuma Zanthorrhiza Roxb -- 10.5.2.1 In Vitro Immunomodulating Effect of C. zanthorrhiza -- 10.5.2.2 In Vivo Immunomodulating Effect of C. zanthorrhiza -- 10.5.3 Curcuma Aeruginosa Roxb -- 10.5.3.1 In Vitro Immunomodulating of C. aeruginosa -- 10.5.3.2 In Vivo Immunomodulating of C. aeruginosa -- 10.5.4 Curcuma Zedoaria (Christm.) Roscoe -- 10.5.4.1 In Vitro Immunomodulating Effect of C. zedoaria -- 10.5.4.2 In Vivo Immunomodulating Effect of C. zedoaria -- 10.5.5 Curcuma Mangga Valeton & -- Zijp -- 10.5.5.1 In Vitro Immunomodulating Effect of C. mangga -- 10.5.5.2 In Vivo Immunomodulating Effect of C. mangga -- 10.5.6 Curcuma Amada Roxb -- 10.6 Conclusion -- References -- Chapter 11: Colchicine and Andrographolide as Natural Immunomodulators. 11.1 Introduction. |
| Record Nr. | UNINA-9910639886003321 |
| Singapore : , : Springer, , [2022] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||