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Microarray analysis : biochips and eradication of all diseases / / Dr. Kal Renganathan Sharma
| Microarray analysis : biochips and eradication of all diseases / / Dr. Kal Renganathan Sharma |
| Autore | Sharma Kal Renganathan |
| Pubbl/distr/stampa | New York, NY : , : Momentum Press Engineering, , 2015 |
| Descrizione fisica | 1 online resource (xxviii, 295 pages) : illustrations |
| Disciplina | 572.8636 |
| Collana | Biomedical engineering collection |
| Soggetto topico | DNA microarrays |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-60650-670-6 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
1. Genominomics and prospects -- Chapter objectives -- Human genome project completed -- Biochips -- Next-generation sequencing -- Applications of biochips -- Consanguinous marriages -- Ashkenazi Jews -- Cystic fibrosis -- Tuberculosis -- Cancer -- Sickle-cell anemia -- Small pox -- Paleo genomes -- Colony collapse disorder -- Schizophrenia -- Prenatal testing -- DNA for forensic investigation -- Genomic surveillance -- Bio-corrosion -- Human immunodeficiency syndrome -- Microarray analysis -- Pioneers in double-helix structure of DNA -- Genominomics, economics of sequencing, $1,000 -- Genome is within reach -- Genetically modified crops -- Glossary -- Summary --
2. Microarray analysis -- Chapter objectives -- Molecular basis for disease -- Microarray technology development -- Specifications -- Nanoprint microarrayer -- Ten tips for five-step process -- Step 1 formulation of a biologic question -- Step 2 sample preparation -- Step 3 biochemical reaction -- Step 4 microarray detection -- Step 5 microarray data analysis and modeling -- Microarray fluorescence detection -- Confocal scanning microscope -- Quality of substrate surface -- Phosphoramadite synthesis -- Summary -- 3. Sequencing technology advances -- Chapter objectives -- Genomes completed -- Next-generation sequencers -- Gene mapping -- Electrophoretic methods -- Microfluidic separations -- Polymer liquids -- Transport parameters -- Transient concentration profile predicted using the a capite ad calcem concentration non-Fick diffusion equation in a semi-infinite medium -- Convection and diffusion -- Summary -- 4. Applications -- Chapter objectives -- Cancer -- Kinetic model for progression of cancer -- Proteomics and Michaelis and Menten kinetics -- Immune action mechanism -- DNA hybridization kinetics-diffusion effects -- Gene modifications -- DNA-melting temperature -- Genetic disorders and microarray analysis -- Tissue microarrays and cell microarrays -- Bio-based polymers -- Gene silencing -- Metabolomics -- Recombinant DNA technology and genetically -- Modified crops -- Biodiesel -- Consecutive-competitive reactions -- Centrifugal separation of fame and glycerol: torque requirements -- Shear flow theory -- Results -- Gene therapy -- Gene activity in songbirds similar to humans -- Glossary -- Summary -- 5. Next-generation sequencing -- Chapter objectives -- Blotting techniques -- Sanger sequencing -- Sequencing by synthesis -- Sequencing by ligation -- Pyrosequencing -- Single-molecule sequencing -- DNA sequencing through nanopore -- Glossary -- Summary -- 6. Biochip manufacturing -- Chapter objectives -- Three approaches -- Ex situ manufacturing -- Commercial instruments -- Time to print -- Summary -- 7. Statistical characterization and normalization -- Chapter objectives -- Housekeeping genes and normalization -- Clustering -- Supervised -- Variation filter -- Unsupervised -- Pearson's correlation coefficient -- Principal component analysis -- Cluster determination -- Nearest neighbor clustering -- Unsupervised classification -- Silhouette method -- Dunn's validation index -- Davies-Bouldin index -- C-index -- Self-organizing maps -- K-means clustering -- Agglomerative clustering -- Dendrograms -- Two-dimensional dendrograms -- Division or partition clustering -- Bayesian clustering -- Boolean networks -- Bayesian networks -- Relevance networks -- Glossary -- Summary -- References -- About the author -- Index. |
| Record Nr. | UNINA-9910460995803321 |
Sharma Kal Renganathan
|
||
| New York, NY : , : Momentum Press Engineering, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Microarray analysis : biochips and eradication of all diseases / / Dr. Kal Renganathan Sharma
| Microarray analysis : biochips and eradication of all diseases / / Dr. Kal Renganathan Sharma |
| Autore | Sharma Kal Renganathan |
| Pubbl/distr/stampa | New York, NY : , : Momentum Press Engineering, , 2015 |
| Descrizione fisica | 1 online resource (xxviii, 295 pages) : illustrations |
| Disciplina | 572.8636 |
| Collana | Biomedical engineering collection |
| Soggetto topico | DNA microarrays |
| ISBN | 1-60650-670-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
1. Genominomics and prospects -- Chapter objectives -- Human genome project completed -- Biochips -- Next-generation sequencing -- Applications of biochips -- Consanguinous marriages -- Ashkenazi Jews -- Cystic fibrosis -- Tuberculosis -- Cancer -- Sickle-cell anemia -- Small pox -- Paleo genomes -- Colony collapse disorder -- Schizophrenia -- Prenatal testing -- DNA for forensic investigation -- Genomic surveillance -- Bio-corrosion -- Human immunodeficiency syndrome -- Microarray analysis -- Pioneers in double-helix structure of DNA -- Genominomics, economics of sequencing, $1,000 -- Genome is within reach -- Genetically modified crops -- Glossary -- Summary --
2. Microarray analysis -- Chapter objectives -- Molecular basis for disease -- Microarray technology development -- Specifications -- Nanoprint microarrayer -- Ten tips for five-step process -- Step 1 formulation of a biologic question -- Step 2 sample preparation -- Step 3 biochemical reaction -- Step 4 microarray detection -- Step 5 microarray data analysis and modeling -- Microarray fluorescence detection -- Confocal scanning microscope -- Quality of substrate surface -- Phosphoramadite synthesis -- Summary -- 3. Sequencing technology advances -- Chapter objectives -- Genomes completed -- Next-generation sequencers -- Gene mapping -- Electrophoretic methods -- Microfluidic separations -- Polymer liquids -- Transport parameters -- Transient concentration profile predicted using the a capite ad calcem concentration non-Fick diffusion equation in a semi-infinite medium -- Convection and diffusion -- Summary -- 4. Applications -- Chapter objectives -- Cancer -- Kinetic model for progression of cancer -- Proteomics and Michaelis and Menten kinetics -- Immune action mechanism -- DNA hybridization kinetics-diffusion effects -- Gene modifications -- DNA-melting temperature -- Genetic disorders and microarray analysis -- Tissue microarrays and cell microarrays -- Bio-based polymers -- Gene silencing -- Metabolomics -- Recombinant DNA technology and genetically -- Modified crops -- Biodiesel -- Consecutive-competitive reactions -- Centrifugal separation of fame and glycerol: torque requirements -- Shear flow theory -- Results -- Gene therapy -- Gene activity in songbirds similar to humans -- Glossary -- Summary -- 5. Next-generation sequencing -- Chapter objectives -- Blotting techniques -- Sanger sequencing -- Sequencing by synthesis -- Sequencing by ligation -- Pyrosequencing -- Single-molecule sequencing -- DNA sequencing through nanopore -- Glossary -- Summary -- 6. Biochip manufacturing -- Chapter objectives -- Three approaches -- Ex situ manufacturing -- Commercial instruments -- Time to print -- Summary -- 7. Statistical characterization and normalization -- Chapter objectives -- Housekeeping genes and normalization -- Clustering -- Supervised -- Variation filter -- Unsupervised -- Pearson's correlation coefficient -- Principal component analysis -- Cluster determination -- Nearest neighbor clustering -- Unsupervised classification -- Silhouette method -- Dunn's validation index -- Davies-Bouldin index -- C-index -- Self-organizing maps -- K-means clustering -- Agglomerative clustering -- Dendrograms -- Two-dimensional dendrograms -- Division or partition clustering -- Bayesian clustering -- Boolean networks -- Bayesian networks -- Relevance networks -- Glossary -- Summary -- References -- About the author -- Index. |
| Record Nr. | UNINA-9910797401003321 |
|
Sharma Kal Renganathan
|
||
| New York, NY : , : Momentum Press Engineering, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Microarray analysis : biochips and eradication of all diseases / / Dr. Kal Renganathan Sharma
| Microarray analysis : biochips and eradication of all diseases / / Dr. Kal Renganathan Sharma |
| Autore | Sharma Kal Renganathan |
| Pubbl/distr/stampa | New York, NY : , : Momentum Press Engineering, , 2015 |
| Descrizione fisica | 1 online resource (xxviii, 295 pages) : illustrations |
| Disciplina | 572.8636 |
| Collana | Biomedical engineering collection |
| Soggetto topico | DNA microarrays |
| ISBN | 1-60650-670-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
1. Genominomics and prospects -- Chapter objectives -- Human genome project completed -- Biochips -- Next-generation sequencing -- Applications of biochips -- Consanguinous marriages -- Ashkenazi Jews -- Cystic fibrosis -- Tuberculosis -- Cancer -- Sickle-cell anemia -- Small pox -- Paleo genomes -- Colony collapse disorder -- Schizophrenia -- Prenatal testing -- DNA for forensic investigation -- Genomic surveillance -- Bio-corrosion -- Human immunodeficiency syndrome -- Microarray analysis -- Pioneers in double-helix structure of DNA -- Genominomics, economics of sequencing, $1,000 -- Genome is within reach -- Genetically modified crops -- Glossary -- Summary --
2. Microarray analysis -- Chapter objectives -- Molecular basis for disease -- Microarray technology development -- Specifications -- Nanoprint microarrayer -- Ten tips for five-step process -- Step 1 formulation of a biologic question -- Step 2 sample preparation -- Step 3 biochemical reaction -- Step 4 microarray detection -- Step 5 microarray data analysis and modeling -- Microarray fluorescence detection -- Confocal scanning microscope -- Quality of substrate surface -- Phosphoramadite synthesis -- Summary -- 3. Sequencing technology advances -- Chapter objectives -- Genomes completed -- Next-generation sequencers -- Gene mapping -- Electrophoretic methods -- Microfluidic separations -- Polymer liquids -- Transport parameters -- Transient concentration profile predicted using the a capite ad calcem concentration non-Fick diffusion equation in a semi-infinite medium -- Convection and diffusion -- Summary -- 4. Applications -- Chapter objectives -- Cancer -- Kinetic model for progression of cancer -- Proteomics and Michaelis and Menten kinetics -- Immune action mechanism -- DNA hybridization kinetics-diffusion effects -- Gene modifications -- DNA-melting temperature -- Genetic disorders and microarray analysis -- Tissue microarrays and cell microarrays -- Bio-based polymers -- Gene silencing -- Metabolomics -- Recombinant DNA technology and genetically -- Modified crops -- Biodiesel -- Consecutive-competitive reactions -- Centrifugal separation of fame and glycerol: torque requirements -- Shear flow theory -- Results -- Gene therapy -- Gene activity in songbirds similar to humans -- Glossary -- Summary -- 5. Next-generation sequencing -- Chapter objectives -- Blotting techniques -- Sanger sequencing -- Sequencing by synthesis -- Sequencing by ligation -- Pyrosequencing -- Single-molecule sequencing -- DNA sequencing through nanopore -- Glossary -- Summary -- 6. Biochip manufacturing -- Chapter objectives -- Three approaches -- Ex situ manufacturing -- Commercial instruments -- Time to print -- Summary -- 7. Statistical characterization and normalization -- Chapter objectives -- Housekeeping genes and normalization -- Clustering -- Supervised -- Variation filter -- Unsupervised -- Pearson's correlation coefficient -- Principal component analysis -- Cluster determination -- Nearest neighbor clustering -- Unsupervised classification -- Silhouette method -- Dunn's validation index -- Davies-Bouldin index -- C-index -- Self-organizing maps -- K-means clustering -- Agglomerative clustering -- Dendrograms -- Two-dimensional dendrograms -- Division or partition clustering -- Bayesian clustering -- Boolean networks -- Bayesian networks -- Relevance networks -- Glossary -- Summary -- References -- About the author -- Index. |
| Record Nr. | UNINA-9910813852703321 |
|
Sharma Kal Renganathan
|
||
| New York, NY : , : Momentum Press Engineering, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Practical applications of engineering economics / / by Kal Renganathan Sharma
| Practical applications of engineering economics / / by Kal Renganathan Sharma |
| Autore | Sharma Kal Renganathan |
| Pubbl/distr/stampa | New York, [New York] (222 East 46th Street, New York, NY 10017) : , : Momentum Press, , 2015 |
| Descrizione fisica | 1 online resource (102 p.) |
| Disciplina | 658.15 |
| Collana | Engineering management collection |
| Soggetto topico | Engineering economy |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-60650-711-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
1. Replacement analysis and depreciation -- 1.1 Overview -- 1.2 MACRS, modified accelerated cost recovery system. Example 1.1. Depreciation charge of off shore drilling asset -- 1.3 Methods of depreciation -- 1.3.1 Method of straight line. Example 1.2. Method of straight line for depreciation of HRA, helical ribbon agitator -- 1.3.2 Method of declining balance. Example 1.3. Method of declining balance line for depreciation of HRA, helical ribbon agitator -- 1.3.2 Method of units of production. Example 1.4. Hexane extraction of rice-bran oil (kindly see example 4.11) -- 1.4 Replacement analysis. Example 1.5. Photocopier before-tax. Example 1.6. Best year for abandonment -- 1.5 Summary -- 1.6 References --
2. Taxes, tariffs and duties -- 2.1 Overview -- 2.2 Tax reform -- 2.3 Types of taxes -- 2.4 Tax consequences of evaluation of a single project -- Example 2.1. Present worth of a sugar MiU after tax consequences. Example 2.2. PW of ABS plant taking into account inflation and tax consequences. Example 2.3. Profitability of liquefaction plants -- 2.5 Summary -- 2.6 References -- 3. Benefit-to-cost ratio and public sector initiatives -- 3.1 Introduction -- 3.1.1 Marshall Plan -- 3.1.2 Taj Mahal -- 3.1.3 Great Wall of China -- 3.1.4 Pyramid of Giza -- 3.1.5 Eiffel Tower -- 3.1.6 Suez Canal -- 3.1.7 Hoover Dam -- 3.1.8 Apollo Program -- 3.1.9 NASA Mars science laboratory mission -- 3.1.10 Interstate highways -- 3.2 B-C-D method. Example 3.1. Firefighting in Yellowstone National Park in 1988. Example 3.2. Replacement for WTG, World Trade Center -- 3.3 Summary -- 3.4 References -- 4. Spider plots and break-even analysis -- 4.1 Overview. Example 4.1. Break-even analysis for PEV, Chevy Volt. Example 4.2. Spider plot for life-cycle cost of Chevy Volt -- Appendices A. Discrete compounding-interest and annuity tables, Table A-1 to Table A-23 -- B. Continuous compounding-interest and annuity tables Table B-1 to B-25. |
| Record Nr. | UNINA-9910466416803321 |
|
Sharma Kal Renganathan
|
||
| New York, [New York] (222 East 46th Street, New York, NY 10017) : , : Momentum Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Practical applications of engineering economics / / by Kal Renganathan Sharma
| Practical applications of engineering economics / / by Kal Renganathan Sharma |
| Autore | Sharma Kal Renganathan |
| Pubbl/distr/stampa | New York, [New York] (222 East 46th Street, New York, NY 10017) : , : Momentum Press, , 2015 |
| Descrizione fisica | 1 online resource (102 p.) |
| Disciplina | 658.15 |
| Collana | Engineering management collection |
| Soggetto topico | Engineering economy |
| ISBN | 1-60650-711-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
1. Replacement analysis and depreciation -- 1.1 Overview -- 1.2 MACRS, modified accelerated cost recovery system. Example 1.1. Depreciation charge of off shore drilling asset -- 1.3 Methods of depreciation -- 1.3.1 Method of straight line. Example 1.2. Method of straight line for depreciation of HRA, helical ribbon agitator -- 1.3.2 Method of declining balance. Example 1.3. Method of declining balance line for depreciation of HRA, helical ribbon agitator -- 1.3.2 Method of units of production. Example 1.4. Hexane extraction of rice-bran oil (kindly see example 4.11) -- 1.4 Replacement analysis. Example 1.5. Photocopier before-tax. Example 1.6. Best year for abandonment -- 1.5 Summary -- 1.6 References --
2. Taxes, tariffs and duties -- 2.1 Overview -- 2.2 Tax reform -- 2.3 Types of taxes -- 2.4 Tax consequences of evaluation of a single project -- Example 2.1. Present worth of a sugar MiU after tax consequences. Example 2.2. PW of ABS plant taking into account inflation and tax consequences. Example 2.3. Profitability of liquefaction plants -- 2.5 Summary -- 2.6 References -- 3. Benefit-to-cost ratio and public sector initiatives -- 3.1 Introduction -- 3.1.1 Marshall Plan -- 3.1.2 Taj Mahal -- 3.1.3 Great Wall of China -- 3.1.4 Pyramid of Giza -- 3.1.5 Eiffel Tower -- 3.1.6 Suez Canal -- 3.1.7 Hoover Dam -- 3.1.8 Apollo Program -- 3.1.9 NASA Mars science laboratory mission -- 3.1.10 Interstate highways -- 3.2 B-C-D method. Example 3.1. Firefighting in Yellowstone National Park in 1988. Example 3.2. Replacement for WTG, World Trade Center -- 3.3 Summary -- 3.4 References -- 4. Spider plots and break-even analysis -- 4.1 Overview. Example 4.1. Break-even analysis for PEV, Chevy Volt. Example 4.2. Spider plot for life-cycle cost of Chevy Volt -- Appendices A. Discrete compounding-interest and annuity tables, Table A-1 to Table A-23 -- B. Continuous compounding-interest and annuity tables Table B-1 to B-25. |
| Record Nr. | UNINA-9910796469903321 |
|
Sharma Kal Renganathan
|
||
| New York, [New York] (222 East 46th Street, New York, NY 10017) : , : Momentum Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Practical applications of engineering economics / / by Kal Renganathan Sharma
| Practical applications of engineering economics / / by Kal Renganathan Sharma |
| Autore | Sharma Kal Renganathan |
| Pubbl/distr/stampa | New York, [New York] (222 East 46th Street, New York, NY 10017) : , : Momentum Press, , 2015 |
| Descrizione fisica | 1 online resource (102 p.) |
| Disciplina | 658.15 |
| Collana | Engineering management collection |
| Soggetto topico | Engineering economy |
| ISBN | 1-60650-711-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
1. Replacement analysis and depreciation -- 1.1 Overview -- 1.2 MACRS, modified accelerated cost recovery system. Example 1.1. Depreciation charge of off shore drilling asset -- 1.3 Methods of depreciation -- 1.3.1 Method of straight line. Example 1.2. Method of straight line for depreciation of HRA, helical ribbon agitator -- 1.3.2 Method of declining balance. Example 1.3. Method of declining balance line for depreciation of HRA, helical ribbon agitator -- 1.3.2 Method of units of production. Example 1.4. Hexane extraction of rice-bran oil (kindly see example 4.11) -- 1.4 Replacement analysis. Example 1.5. Photocopier before-tax. Example 1.6. Best year for abandonment -- 1.5 Summary -- 1.6 References --
2. Taxes, tariffs and duties -- 2.1 Overview -- 2.2 Tax reform -- 2.3 Types of taxes -- 2.4 Tax consequences of evaluation of a single project -- Example 2.1. Present worth of a sugar MiU after tax consequences. Example 2.2. PW of ABS plant taking into account inflation and tax consequences. Example 2.3. Profitability of liquefaction plants -- 2.5 Summary -- 2.6 References -- 3. Benefit-to-cost ratio and public sector initiatives -- 3.1 Introduction -- 3.1.1 Marshall Plan -- 3.1.2 Taj Mahal -- 3.1.3 Great Wall of China -- 3.1.4 Pyramid of Giza -- 3.1.5 Eiffel Tower -- 3.1.6 Suez Canal -- 3.1.7 Hoover Dam -- 3.1.8 Apollo Program -- 3.1.9 NASA Mars science laboratory mission -- 3.1.10 Interstate highways -- 3.2 B-C-D method. Example 3.1. Firefighting in Yellowstone National Park in 1988. Example 3.2. Replacement for WTG, World Trade Center -- 3.3 Summary -- 3.4 References -- 4. Spider plots and break-even analysis -- 4.1 Overview. Example 4.1. Break-even analysis for PEV, Chevy Volt. Example 4.2. Spider plot for life-cycle cost of Chevy Volt -- Appendices A. Discrete compounding-interest and annuity tables, Table A-1 to Table A-23 -- B. Continuous compounding-interest and annuity tables Table B-1 to B-25. |
| Record Nr. | UNINA-9910811567203321 |
|
Sharma Kal Renganathan
|
||
| New York, [New York] (222 East 46th Street, New York, NY 10017) : , : Momentum Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||