Hydrophilic Vitamins in Health and Disease

• Autore: Shah Anureet K
• Pubblicazione: Cham : , : Springer International Publishing AG, , 2024; ©2024
• Edizione: 1st ed.
• Descrizione fisica: 1 online resource (407 pages)
• Altri autori: TappiaParamjit S DhallaNaranjan S
• Nota di contenuto: Intro -- Preface -- Contents -- Contributors -- Part I General Aspects of Hydrophilic Vitamins -- 1 The Cardio-protective Effect of Water-Soluble Vitamins on Anticancer Drug-Induced Cardiotoxicity -- Introduction -- Chemotherapeutic Drugs Causing Cardiotoxicity -- Cardio-Protective Vitamins -- Conclusion and Discussion -- References -- 2 Water Soluble Vitamins in the Ocular and Cardiac Diseases: Application of These Vitamins as Biosensors and in Related Epigenetic Changes -- The Role of Water-Soluble Vitamins in Eye Health and Disease -- Vitamins and Biosensors -- Vitamin Detection and Measurement -- Point-of-Care Diagnostics -- Nutritional Monitoring -- Customized Nutritional Plans -- Research and Drug Development -- Feedback for Health Apps -- Vitamins and Epigenetics -- DNA Methylation -- Nutrigenomics -- Histone Modifications -- Vitamin D -- Vitamin A -- MicroRNAs -- Developmental Programming -- Disease Risk -- Nutrigenomics -- Personalized Nutrition -- Conclusions -- References -- 3 Antiatherogenic Effects of Vitamins, Mediterranean Diet and DASH Diet: An Overview for the Prevention of Cardiovascular Diseases -- Introduction -- Pathophysiology of Atherosclerosis -- Influence of Antioxidant and Anti-inflammation Diets on Atherosclerosis -- Vitamin C or Ascorbic Acid -- Vitamin E -- Polyunsaturated Fatty Acids (PUFA) -- Vitamin D -- Vitamin B -- Niacin (Vitamin B3) -- Folic Acid (Vitamin B9) -- Vitamin B12 -- Vitamin B6 -- Vitamin B2 -- Nutritional Benefits of DASH DIET, Mediterranean Diet for the Prevention of Atherosclerosis, Hypertension, and Coronary Heart Disease -- Mediterranean Diet -- Closing Remarks -- References -- 4 Role of Vitamins in Health and Disease: A Vitamin B Perspective -- Introduction -- B Vitamins in Health and Disease -- Effects of B Vitamins on Metabolism and Related Disorders. ; Effects of B Vitamins on Neurology and Mental Health -- Effects of B Vitamins on Hematology and Immunity -- Effects of B Vitamins on Bone Mineralization -- Effects of B Vitamins on Cancer Cells -- Conclusion -- Conflicts of Interest -- References -- 5 Discovering the Potential of Bee Bread from Malaysian Stingless Bee as Vitamins B1, B3, and B6-Rich Source for Health and Disease -- Introduction -- Hydrophilic Vitamins in Bee Bread -- Vitamin B1 (Thiamine) in Bee Bread for Health and Disease -- Vitamin B3 in Bee Bread for Health and Disease -- Vitamin B6 in Bee Bread for Health and Disease -- Conclusions -- References -- 6 The Protective Role of Vitamins in Skincare and Cosmeceutical Products: Mechanisms Involved to Re-engineer the Skin Towards a Healthy State -- Introduction -- Vitamin A and Retinoids -- Protective Role of Vitamin A Against Ultraviolet Radiation -- Functions of Vitamin A and Retinoids in Skin Care Products -- Future Possibility of Making Anti-ageing Products Containing Vitamin A -- Vitamin B3 -- Vitamin C -- Vitamin D -- Vitamin E -- Worldwide Sale of Skin Care and Cosmeceutical Products -- Summary and Future Directions -- References -- 7 Natural and Plant-Derived Vitamins: A Comprehensive Review of Biochemistry, Pharmacology and Nutritional Benefits in Health and Disease -- Introduction -- Vitamin A -- Biochemistry of Vitamin A -- Pharmacology of Vitamin A -- Dietary Sources and Physiological Functions of Vitamin A -- Vitamin B -- Thiamine (Vitamin B1) -- Source of Thiamine -- Pharmacology of Thiamine -- Consequences of Thiamine Deficiency -- Riboflavin (Vitamin B2) -- Sources of Riboflavin -- Pharmacology of Riboflavin -- Physiological Functions of Riboflavin -- Flavoproteins -- Physiological Functions of Flavoproteins in Health and Disease -- Clinical Consequences of Riboflavin Deficiency -- Niacin (Vitamin B3). ; Sources of Niacin -- Pharmacology of Niacin -- Clinical Implications of Niacin Deficiency -- Neurological Disorders -- Toxicity of Niacin -- Pantothenic Acid (Vitamin B5) -- Sources of Pantothenic Acid -- Physiological Functions of Pantothenic Acid -- Pharmacology of Pantothenic Acid -- Vitamin B6 -- Biosynthesis of Vitamin B6 -- Pharmacology -- Dietary Sources of Vitamin B6 -- Biotin (Vitamin B7) -- Biochemistry of Biotin -- Pharmacology of Biotin -- Intake and Food Sources of Biotin -- Usefulness of Biotin -- Folic Acid (Vitamin B9) -- Biochemistry of Folic Acid -- Pharmacology of Folic Acid -- Dietary Sources of Folic Acid -- Health Benefits of Folic Acid -- Vitamin B12 -- Biochemistry of Vitamin B12 -- Pharmacology of Vitamin B12 -- Dietary Sources of Vitamin B12 -- Ascorbic Acid (Vitamin C) -- Dietary Sources of Vitamin C -- Biochemistry of Vitamin C -- Pharmacology of Vitamin C -- Benefits of Vitamin C in Health and Disease -- Vitamin D -- Endogenous Formation: Photosynthesis of Vitamin D3 in Human Skin -- Biological Mechanism of Action of Vitamin D -- Clinical Applications of Vitamin D -- Vitamin E -- α-Tocopherol Synthesis and Regulations -- Pharmacology of Vitamin E -- Food Sources of Vitamin E -- Benefits of Vitamin E in Health and Disease -- Vitamin K -- Dietary Source of Vitamin K -- Physiological Functions and Pharmacokinetics of Vitamin K -- Sequelae of Vitamin K Deficiency -- Toxicity of Vitamin K -- Conclusions and Relevance -- References -- 8 Unraveling the Mechanisms of Hydrophilic Vitamins in Alzheimer's and Parkinson's: Preclinical and Clinical Evidence -- Introduction -- Neuroprotective Mechanisms of Vitamin C in Neurodegenerative Diseases -- Vitamin C and Alzheimer's Disease -- Vitamin C and Parkinson's Disease -- Neuroprotective Mechanisms of Vitamin B Complex in Neurodegenerative Diseases -- Vitamin B in Alzheimer's Disease. ; Vitamin B Complex in Parkinson's Disease -- Conclusion and Future Perspectives -- References -- Part II Functionality of B Vitamins in Health and Disease -- 9 The Interplay of Thiamine and Cardiovascular Diseases -- Introduction -- Thiamine Metabolism and Signal Transduction -- Thiamine Absorption and Transport -- The Role of Thiamine in Metabolic Processes -- Thiamine Deficiency and Cardiovascular Diseases -- Thiamine Deficiency and Diabetes Mellitus -- Thiamine Deficiency and Heart Failure -- References -- 10 Vitamin B7 (Biotin) and Its Role in Hair, Skin and Nail Health -- Introduction -- Vitamin B7 [Biotin]-Overview -- Sources of Biotin -- Biotin's Involvement in Essential Metabolic Processes -- Biotin and Hair Health -- Structure and Growth Cycle of Hair -- Biotin and Hair Loss -- How Biotin Contributes to Hair Strength, Texture, and Growth -- Biotin and Skin Health -- Skin's Crucial Role as a Protective Barrier: -- Biotin's Significance in Sustaining Healthy Skin Cells -- Potential Benefits of Biotin for Promoting a Youthful and Glowing Complexion -- Biotin and Nail Health -- Recognizing the Signs of Biotin Deficiency (Hair Thinning, Skin Rash, Brittle Nails) -- Hair Thinning and Hair Loss -- Skin Rash (Dermatitis) -- Brittle Nails (Onychoschizia) -- Conjunctivitis (Eye Inflammation) -- Neurological Symptoms (Rare) -- Biotin Supplementation -- Consultation with Healthcare Professionals Before Starting Biotin Supplementation -- Conclusion -- References -- 11 Role of Vitamin B12 in Cardiovascular Disease -- Introduction -- Vitamin B12 in Different Types of CVD -- Vitamin B12 Deficiency Induced Anemia and Heart Failure -- Vitamin B12 Deficiency in Pediatric/Adolescent Populations -- Role of Vitamin B12 in CVD Risk in Diabetes -- Conclusion -- References -- 12 Association of Vitamin B12 with Bone Mineral Density -- Introduction. ; Biochemistry and Physiology of Vitamin B12 -- Evidence from Different Experimental and Observational Studies -- Conclusions -- References -- 13 Mechanistic Effects of Vitamin B6 and B12 on Inflammation and Cancer -- Introduction -- The Link Between Inflammation and Cancer -- Vitamin B6 -- The Mechanistic Role of Vitamin B6 in Inflammation and Cancer -- Inflammatory Mediators and Inflammasome Pathways -- Oxidative Stress Pathways -- Vitamin B6 and Advanced Glycation End Products (AGEs) -- Hydrogen Sulphide, Trans-Sulphuration, and Vitamin B6 Relationship -- Sphingosine-1-Phosphate and Vitamin B6 -- Telomere Length and Vitamin B6 -- Vitamin B6 as an Immunomodulatory Agent in Cancer -- Vitamin B12 -- Vitamin B12 and One-Carbon Metabolism -- Vitamin B12 Status on Inflammation and Cancer -- Involvement of Vitamin B12 in DNA Methylation and Cancer -- Conclusion -- References -- 14 The Interweaving of B9- and B12-Dependent Reactions and Their Clinical Implications -- Introduction -- Discovery -- Structure and Absorption of Folate -- Structure and Absorption of Vitamin B12 -- Metabolic Processes -- The Homocysteine-Methionine Axis -- The Folate Shuttle -- Clinical Applications -- Genetics and Epigenetics -- The Circulatory System -- The Epithelial Tissues -- The Nervous System -- The Vascular System -- Malignancies -- Conclusions -- References -- 15 The Role of Folic Acid in the Regulation of Homocysteine Levels and Cardiovascular Disease -- Introduction -- The Mechanism of Folic Acid and Homocysteine Regulation -- Structural and Functional Effects of Homocysteine Engender Cardiovascular Implications -- Lowering Blood Homocysteine Levels Through Supplementation -- Changes in Lifestyle and Dietary Sources -- Elevated Homocysteine Levels Engender Cardiovascular Implications -- Elevated Blood Pressure -- High Cholesterol -- Physical Inactivity -- Obesity. ; Stress and Anxiety.
• Titolo autorizzato: Hydrophilic Vitamins in Health and Disease
• ISBN: 3-031-55474-4
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910864183403321
• Lo trovi qui: Univ. Federico II
• Serie: Advances in Biochemistry in Health and Disease Series