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Advanced Drug Delivery : Methods and Applications / / edited by Tuhin Subhra Santra, Ashwini Uma Surendra Shinde
| Advanced Drug Delivery : Methods and Applications / / edited by Tuhin Subhra Santra, Ashwini Uma Surendra Shinde |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (368 pages) |
| Disciplina | 615.6 |
| Collana | Studies in Mechanobiology, Tissue Engineering and Biomaterials |
| Soggetto topico |
Drug delivery systems
Biomedical engineering Nanobiotechnology Microfluidics Cytology Pharmaceutical chemistry Drug Delivery Biomedical Engineering and Bioengineering Cell Biology Pharmaceutics |
| ISBN | 981-9965-64-0 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1. Biological methods -- Chapter 2. Liposomal based drug delivery system -- Chapter 3. Hydrogel-based drug delivery strategies -- Chapter 4. Monoclonal antibodies -- Chapter 5. Electroporation -- Chapter 6. Photoporation -- Chapter 7. Mechanoporation -- Chapter 8. Magnetoporation -- Chapter 9. Microinjection -- Chapter 10. Jet injection -- Chapter 11. Sonoporation -- Chapter 12. Device based drug delivery techniques – microfluidics Chapter 13. Nanoparticles drug delivery systems -- Chapter 14. BioMaterials -- Chapter 15. Implanted drug delivery systems -- Chapter 16. Transdermal drug delivery systems -- Chapter 17. Subcutaneous drug delivery systems -- Chapter 18. Nasopulmonary drug delivery systems -- Chapter 19. Mucosal drug delivery systems -- Chapter 20. Intrauterine drug delivery systems -- Chapter 21. Gastro retentive drug delivery systems -- Chapter 22. Endoscopic assisted drug delivery -- Chapter 23. Theranostics. |
| Record Nr. | UNINA-9910754097503321 |
| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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cmaterials and their biomedical applications / / Tuhin Subhra Santra, Loganathan Mohan, editors
| cmaterials and their biomedical applications / / Tuhin Subhra Santra, Loganathan Mohan, editors |
| Edizione | [1st ed. 2021.] |
| Pubbl/distr/stampa | Gateway East, Singapore : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (X, 552 p. 158 illus., 137 illus. in color.) |
| Disciplina | 620.115 |
| Collana | Springer Series in Biomaterials Science and Engineering |
| Soggetto topico | Nanostructured materials |
| ISBN | 981-336-252-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Nanomaterials: An Introduction -- Metallic Nanoparticles for Biomedical Applications -- Size and Shape Selective Metal Oxide Nanomaterials: Preparation, Characterization and Prospective Biomedical Applications -- Nanofibers and Nanosurfaces -- Nanoceramics: Synthesis, Characterizations, and Applications -- Biomedical Applications of Carbon-Based Nanomaterials -- Solution Combustion Synthesis of Calcium Phosphate-Based Bioceramic Powders for Biomedical Applications -- Nanomaterials in Medicine -- Hydrogels: Biomaterials for Sustained and Localized Drug Delivery -- Nanomaterials: Versatile Drug Carriers for Nanomedicine -- Nanomaterials for Medical Implants -- Fabrication of Nanostructured Scaffolds for Tissue Engineering Applications -- Nanomaterials for Medical Imaging and In Vivo Sensing -- Nanomaterials: Surface Functionalization, Modification and Applications -- Laser Induced Micro/Nano Functional Surfaces on Metals for Biomedical Applications -- Surface Nanostructuring of Metallic Materials for Implant Applications -- Tailoring the Surface Functionalities of Titania Nanotubes for Biomedical Applications. |
| Record Nr. | UNINA-9910484366603321 |
| Gateway East, Singapore : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Essentials of Single-Cell Analysis : Concepts, Applications and Future Prospects / / edited by Fan-Gang Tseng, Tuhin Subhra Santra
| Essentials of Single-Cell Analysis : Concepts, Applications and Future Prospects / / edited by Fan-Gang Tseng, Tuhin Subhra Santra |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (415 p.) |
| Disciplina | 571.6028 |
| Collana | Series in BioEngineering |
| Soggetto topico |
Biomedical engineering
Biotechnology Bioinformatics Biophysics Cytology Biomedical Engineering and Bioengineering Microengineering Biological and Medical Physics, Biophysics Cell Biology |
| ISBN | 3-662-49118-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Single Cell Behavioral Assays for Heterogeneity Studies -- Systems biology in single cells -- Electroporation for single cell analysis -- Microinjection for single cell analysis -- Optical tools for single cell manipulation and analysis -- Optoelectrokinetic manipulation for cell analysis -- Continuous micro/nano-fluidic devices for single cell analysis -- Single Cell Mechanical Properties: Label-Free Biomarkers for Cell Status Evaluation -- Cytometry of single cells for biology and biomedicine -- Single cell genomics and epigenomics -- Single cell Metabolomics -- Applications of cell based drug delivery systems: use of single cell assay -- Applications of Single Cell Sequencing in Cancer -- Single Cell Characterization of Microalgal Lipid Contents with Confocal Raman Microscopy -- Single Differentiated Neurons from Pluripotent Embryonic Stem Cells: Motor Protein Modelling and Neurodegenerative Disease. |
| Record Nr. | UNINA-9910254249803321 |
| Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Handbook of Single Cell Technologies [[electronic resource] /] / edited by Tuhin Subhra Santra, Fan-Gang Tseng
| Handbook of Single Cell Technologies [[electronic resource] /] / edited by Tuhin Subhra Santra, Fan-Gang Tseng |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020 |
| Disciplina | 610.28 |
| Soggetto topico |
Biomedical engineering
Biotechnology Cytology Biophysics Biomedical Engineering and Bioengineering Microengineering Cell Biology Biological and Medical Physics, Biophysics |
| ISBN | 981-10-4857-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910337615203321 |
| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Handbook of single-cell technologies / / Tuhin Subhra Santra, Fan-Gang Tseng, editors
| Handbook of single-cell technologies / / Tuhin Subhra Santra, Fan-Gang Tseng, editors |
| Pubbl/distr/stampa | Singapore : , : Springer, , [2022] |
| Descrizione fisica | 1 online resource (1091 pages) |
| Disciplina | 571.6028 |
| Soggetto topico |
Cytology - Technique
Cells - Analysis |
| ISBN | 981-10-8953-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Contents -- About the Editors -- Contributors -- Part I: Physical Methods for Single Cell Therapy and Analysis -- 1 Light-Induced Cellular Delivery and Analysis -- Introduction -- Light-Induced Intracellular Delivery from Bulk to Single-Cell Photoporation -- Direct Laser-Cell Interaction -- Indirect Laser-Cell Interaction -- Pulsed Laser Systems for Optoporation -- Nanosecond Laser -- Femtosecond Laser -- Modifications of the Method -- Applications of Single-Cell Surgery -- Conclusion -- References -- 2 Mechanoporation: Toward Single Cell Approaches -- Introduction -- Types of Mechanoporation -- Particle Bombardment -- Microinjection -- Nanoneedle AFM Tip -- Microinjection Using Microfluidic Platforms -- Parallel Delivery -- Oscillating Nanoneedle Array -- Pressure Driven Devices -- Hydrodynamic Effect -- Sonoporation -- Shear Flow Devices -- A Cone and Plate Shearing Device -- Microchannel-Based Devices -- Mechanical Confinement -- High-Throughput Parallel Mechanical Confinement Device -- Microfluidic Devices -- Constriction Channel-Based Delivery -- Cell Squeeze Platform -- DNA Transfection Via Mechanical and Electrical Cell Membrane Disruption -- Advantages and Limitations of Mechanoporation -- Future Prospects -- Summary -- References -- 3 Single-Cell Electroporation -- Introduction -- Brief History -- Operation Mechanism -- Challenges in Macroscale Electroporation -- Landscape Transformation -- Electroporation Theories -- Intracellular Molecular Transport -- Cell Membrane Resealing Dynamics -- Microscale Electroporation -- Patch-Clamp Based Techniques -- Patch-Free Techniques -- Feedback-Driven Approaches -- Conclusion and Future Outlook -- References -- 4 Microinjection for Single-Cell Analysis and Therapy -- Introduction -- Development of Microinjection -- History of Microinjection.
Types of Cargos Used for Microinjection -- Types of Host Cells Used in Microinjection -- Instruments for Microinjection -- Microinjection for Single-Cell Analysis -- Injection for Analysis of Changes in Cells -- Transgenic Animal Production -- Modern Advancements for Increasing Efficiency -- Microinjection for Single-Cell Therapy -- Intracytoplasmic Sperm Injection for Treatment of Infertility -- Gene Therapy by Injection -- Microneedles for Therapeutic Uses -- Advantages -- Disadvantages -- Future Perspective and Conclusion -- References -- Part II: Fluidic System and Integration -- 5 Single-Cell Manipulation -- Introduction -- Flow Modeling of Hydrodynamic Cell Manipulation -- Fluidic Resistance Versus Electric Resistance -- Conservation of Mass and Energy Versus Kirchhoff´s Current Law and Voltage Law -- Division of Pressure and Flow Rate Versus Division of Voltage and Current -- Examples of Microfluidic Manipulation -- Single-Cell Trapping -- Co-culture of Single Cells -- Deforming, Sorting, and Separating Single Cells -- Integration with Other Methods -- Optical Integration -- Dielectrophoretic Integration -- Magnetic Integration -- Acoustic Integration -- Conclusion -- References -- 6 Single Cell Manipulation Using Macro-scale Actuator -- Introduction -- Transfer Function of Macro-to-Micro Manipulation (Mizoue et al. 2017) -- The Driving Mechanism -- Mechanical Model -- System Identification Through Experiments -- On-Chip Transmitter for Enhancing Manipulation Speed (Monzawa et al. 2015) -- Advantages of Using an Actuation Transmitter -- Mechanical Model and Theoretical Basis -- Experimental Validation on Manipulation with an Actuation Transmitter -- Recent Works and Applications -- Summary -- References -- 7 Inertial Microfluidics for Single-Cell Manipulation and Analysis -- Introduction -- Underlying Physics -- Inertial Migration. Dean Flow -- Viscoelasticity -- Guidelines for Designing Spiral Inertial Microfluidics -- Dimensionless Numbers -- Design Guidelines -- Cross-Sectional Dimensions -- Channel Length (Loop Number) -- Other Structural Parameters -- Other Functional Units -- Operational Parameters -- Improved Understandings on Spiral Inertial Microfluidics -- Application Guidelines for Spiral Inertial Microfluidics -- Focusing/Ordering -- Separation -- Concentration/Microfiltration -- Conclusion and Future Perspective -- References -- 8 Digital Microfluidics for Single Cell Manipulation and Analysis -- Introduction -- DMF Systems -- DMF Technology -- Electrowetting-on-Dielectric -- Electrodewetting -- Liquid Dielectrophoresis -- Dielectrophoresis -- Optoelectrowetting -- Optoelectronic Tweezers -- Magnetic Force -- Fabrication of DMF -- DMF Manipulation and Analysis of a Single Cell -- Adherent Cell -- Suspension Cell -- Long-Term Culture -- Related Applications of DMF -- Cell Sorting and Concentrating -- 3D Cell Culture -- Diagnosis and Clinical Application -- Conclusions and Future Outlook -- References -- 9 Single-Cell Separation -- Introduction -- Conventional Cell Separation Techniques -- Centrifugation -- Fluorescence-Activated Cell Sorting -- Magnetic-Activated Cell Sorting -- Laser Capture Microdissection -- Manual Cell Picking -- Microfluidic Single-Cell Separation Techniques -- Microfluidic Passive Separation Techniques -- Filter-Based Separation -- Deterministic Lateral Displacement -- Hydrodynamic Separation -- Non-inertial Hydrodynamic Separation -- Inertial Hydrodynamic Separation -- Microfluidic Active Separation Techniques -- Dielectrophoresis (DEP) -- Magnetic Separation -- Acoustophoresis -- Affinity-Based Separation -- Comparison Between Different Microfluidic Separation Techniques -- Conclusion -- References. 10 Technologies for Automated Single Cell Isolation -- Introduction -- Cell Samples -- Size and Morphology of Cells -- Sample Preparation: Single-Cell Suspensions -- Basic Considerations, Definitions, and Classifications for Single-Cell Isolation -- Automated Single-Cell Isolation Technologies -- Limiting Dilution -- Suitability for Microbial Cells -- Fluorescence-Activated Cell Sorting -- Suitability for Microbial Cells -- Single-Cell Dispensing (SCD) -- Suitability for Microbial Cells -- Microfluidic Single-Cell Isolation -- Hydrodynamic Trapping -- Vertical Trapping in Nanowells -- Suitability for Microbial Cells -- Droplet Microfluidics -- Single-Cell Manipulation (on Microfluidic Chips) by Directed External Forces -- Optical Tweezers (OT) -- Dielectrophoresis (DEP) -- Suitability for Microbial Cells -- Automated Micromanipulators -- Discussion and Conclusion -- References -- 11 Dual-Well Microfluidic Technique for Single Cell Isolation and Long-Term Clonal Culture -- Introduction -- Applications of Monoclonal Cell Culture -- Overview of Single Cell Isolation Methods for Clonal Culture -- The Design Concept of the Dual-Well Technique -- Fabrication of Dual-Well Device -- Fabrication of Master Molds by Photolithography Technology -- Molding PDMS Device with the Master Molds -- Dual-Well Device Preparation for Single Cell Isolation -- Cell Suspension Preparation for Single Cell Isolation with Dual-Well Device -- Single Cell Isolation and Clonal Culture with Dual-Well Device -- Culture Medium Replacement of the Dual-Well Device -- Discussion -- The Effect of Capture Well Depth on Single Cell Efficiency -- The Effect of Washing Flow Rate on Single Cell Efficiency -- The Effect of Cell Type on Single Cell Capture Efficiency -- The Effect of Device Flipping on Cell Transfer Efficiency. Single Cell-Derived Clonal Colonies and Stem Cell Differentiation in the Microwells of the Dual-Well Device -- Conclusion -- References -- 12 Single-Cell Cultivation Utilizing Microfluidic Systems -- Introduction -- Purpose of Single-Cell Cultivation -- Morphology -- Proliferation and Differentiation -- Migration -- Genomics, Transcriptomics, Proteomics, and Metabolomics -- Epigenomics -- Single-Cell Cultivation in Microfluidic Devices -- Cell Coculture -- Neural Coculture -- Coculture of Tumor Cells to Neighboring Cells -- Coculture of Neurons and Cancer Cells -- Molecule-Induced Cellular Behaviors -- Molecular Cue-Guided Neuron -- Molecule and Immune Cell Interaction -- Molecule and Microbe Interaction -- Regeneration -- Axotomy -- Stem Cell-Based Regeneration -- Further Limitations and Future Prospects -- Conclusion -- References -- 13 Integrated Microwell Array Technologies for Single Cell Analysis -- Introduction -- Microfabrication of a Microwell Array -- Material and Design Considerations -- Soft Photolithography for Fast Prototyping of Microwell Arrays -- Hydrophilic-in-Hydrophobic Microwells -- Polyethylene Glycol Microwells for Reduced Non-specific Adsorption -- Single Cell Docking -- Docking Strategies: Manual Administration of Cells -- Docking Strategies: Microfluidics-Assisted Administration of Cells -- Continuous Flow Microfluidics -- Digital Microfluidics -- Single Cell Manipulation -- Optical Manipulation -- Magnetic Manipulation -- Mechanical Manipulation -- Electric Manipulation -- Applications -- Single Cell Drug Screening -- Single Cell Omics -- Detection of Single Cell Secreted Products -- Other Applications -- Conclusion -- References -- 14 Micro- and Nanopore Technologies for Single-Cell Analysis -- Coulter Principle -- A History Behind the Invention of Coulter Principle -- Single-Cell Counting Mechanism. Single-Cell Analysis with Conventional Coulter Counters. |
| Record Nr. | UNINA-9910508470903321 |
| Singapore : , : Springer, , [2022] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Single Cell Analysis
| Single Cell Analysis |
| Autore | Santra Tuhin Subhra |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (254 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
artificial intelligence
biomedical applications cardiomyocytes cell heterogeneity cholestatic liver injury circulating tumor cells cluster analysis commercialization conventional approaches copy number alterations diagnostics electrophysiological recording genome hepatocyte heterogeneity immunofluorescence immunohistochemistry infectious disease inflammation isolation laser microdissection liver tissue repair localized high-risk prostate cancer mapping micro/nanofluidic devices microelectrode array microfluidic technologies microfluidics monoclonal cell lines n/a non-small cell lung cancer pathophysiology precision medicine protein protein characterization proteomics RNA velocity sarcoma seurat single cell single cell mass cytometry single cell proteomics single-cell analysis single-cell cloning single-cell RNA sequencing single-neuron models snRNA-seq somatic single nucleotide variants therapeutics therapy three-dimensional (3-D) telomere profiling three-dimensional tissue culture total mRNA level transcriptome size transfection whole-exome genome sequencing |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557388703321 |
Santra Tuhin Subhra
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Single Cell Analysis in Biotechnology and Systems Biology / / edited by Fan-Gang Tseng, Tuhin Subhra Santra
| Single Cell Analysis in Biotechnology and Systems Biology / / edited by Fan-Gang Tseng, Tuhin Subhra Santra |
| Pubbl/distr/stampa | Basel, Switzerland : , : MDPI, , 2016 |
| Descrizione fisica | 1 online resource (236 pages) |
| Disciplina | 641.3 |
| Soggetto topico | Single cell proteins |
| ISBN |
9783038421948
3038421944 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910688578703321 |
| Basel, Switzerland : , : MDPI, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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