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Cholesterol and PI(4,5)P2 in vital biological functions : from coexistence to crosstalk / / edited by Avia Rosenhouse- Dantsker
| Cholesterol and PI(4,5)P2 in vital biological functions : from coexistence to crosstalk / / edited by Avia Rosenhouse- Dantsker |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2023] |
| Descrizione fisica | 1 online resource (438 pages) |
| Disciplina | 405 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico | Phosphoinositides |
| ISBN |
9783031215476
9783031215469 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- 1. Mutual influence of cholesterol and PI(4,5)P2 on their levels -- Chapter 1. Mechanism of the regulation of plasma cholesterol levels by PI(4,5)P2 -- Chapter 2. Effect of cholesterol depletion on ciliary PI(4,5)P2 levels -- Chapter 3. Impact of cholesterol on PI(4,5)P2 levels in the brain -- Chapter 4. Alterations in PIP2 levels in the intracellular cholesterol trafficking disorder NPC1 -- Chapter 5. Targeting cholesterol release and PI(4,5)P2 redistribution by the oral drug Miltefosine -- 2. Cross-talk between cholesterol and PI(4,5)P2 as a factor affecting protein function -- A. Plasma membrane ion channels -- Chapter 6. From cross-talk to synergism: the combined effect of cholesterol and PI(4,5)P2 on inwardly rectifying potassium channels -- Chapter 7. Link between lysosomal cholesterol and PI(4,5)P2 in the regulation of the voltage gated KCNQ2/3 potassium channel -- Chapter 8. Cholesterol and PI(4,5)P2 binding to a ciliary membrane transient receptor potential channel -- Chapter 9. Regulation of ell by cholesterol and PI(4,5)P2 -- Chapter 10. Cholesterol stimulates the epithelial sodium channel in a PI(4,5)P2-dependent manner -- Chapter 11. Roles of cholesterol and PI(4,5)P2 in store operated calcium entry -- Chapter 12. Roles of cholesterol and PI(4,5)P2 levels in the modulation of the calcium activated chloride channel TMEM16A -- B. Lipid transport proteins--Chapter 13. PI(4,5)P2 facilitates ORP1-mediated cholesterol transport by promoting membrane targeting and cholesterol extraction -- Chapter 14. Role of PI(4,5)P2 binding in ORP2-mediated cholesterol distribution -- Chapter 15. PI(4,5)P2-dependent transport of cholesterol from lysosomes to peroxisomes at lysosomeperoxisome contact sites -- 3. Cellular processes at the intersection of cholesterol and PI(4,5)P2 involvement -- Chapter 16. The insertion of the N-terminal domain of Gasdermin-D is increased by PI(4,5)P2 and decreased by cholesterol -- Chapter 17. Cholesterol promotes the cooperative interaction of formins with PI(4,5)P2 to initiate actin nucleation -- Chapter 18. Cooperation between cholesterol and PI(4,5)P2 in the regulation of Engrailed-2 homeoprotein intercellular trafficking -- Chapter 19. Cholesterol and PI(4,5)P2 as a membrane nanoplatform for HIV assembly -- Chapter 20. Role of Cholesterol and PI(4,5)P2 in the localization of the HIV-1 structural polyprotein Gag to the plasma membrane. |
| Record Nr. | UNINA-9910686773403321 |
| Cham, Switzerland : , : Springer, , [2023] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Cholesterol Modulation of Protein Function : Sterol Specificity and Indirect Mechanisms / / edited by Avia Rosenhouse-Dantsker, Anna N. Bukiya
| Cholesterol Modulation of Protein Function : Sterol Specificity and Indirect Mechanisms / / edited by Avia Rosenhouse-Dantsker, Anna N. Bukiya |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (200 pages) |
| Disciplina |
612.0153
572.5795 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Proteomics
Proteins Cell membranes Molecular biology Protein Science Membrane Biology Molecular Medicine |
| ISBN | 3-030-04278-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part 1. Sterol specificity in modulating protein function: 1. Chirality effect on cholesterol modulation of protein function -- 2. A critical analysis of molecular mechanisms underlying membrane cholesterol sensitivity of GPCRs -- 3. Regulation of BK channel activity by cholesterol and its derivatives -- 4. Chiral specificity of cholesterol orientation within cholesterol binding sites in inwardly rectifying potassium channels -- Part 2. Indirect modulation of protein function by cholesterol: 5. Cholesterol effect on the physical properties of lipid membranes -- 6. Effect of cholesterol on the dipole potential of lipid membranes -- 7. Mass spectroscopy imaging of cholesterol -- 8. Cholesterol-dependent gating effects on ion channels. |
| Record Nr. | UNINA-9910337949603321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Direct Mechanisms in Cholesterol Modulation of Protein Function / / edited by Avia Rosenhouse-Dantsker, Anna N. Bukiya
| Direct Mechanisms in Cholesterol Modulation of Protein Function / / edited by Avia Rosenhouse-Dantsker, Anna N. Bukiya |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (179 pages) |
| Disciplina |
612.0153
572.5795 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Proteomics
Proteins Cell membranes Molecular biology Protein Science Membrane Biology Molecular Medicine |
| ISBN | 3-030-14265-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- Direct binding of cholesterol to proteins -- Cholesterol-recognition motifs in membrane proteins -- Molecular determinants of cholesterol binding to proteins: overview of crystallographic studies -- Crystallographic studies of steroid-protein interactions -- Insights into cholesterol binding sites in proteins from computational studies -- Cholesterol binding to NPC1/NPC2 -- I Biophysical elements of the interaction between cholesterol and the nicotinic acetylcholine receptor -- Modulation of TRPV1 channels by cholesterol -- Cholesterol binding sites in inwardly rectifying potassium channels. |
| Record Nr. | UNINA-9910337938403321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||