Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Adaptive designs : selected proceedings of a 1992 joint AMS-IMS-SIAM summer conference / / Nancy Flournoy and William F. Rosenberger, editors [[electronic resource]]
| Adaptive designs : selected proceedings of a 1992 joint AMS-IMS-SIAM summer conference / / Nancy Flournoy and William F. Rosenberger, editors [[electronic resource]] |
| Autore | Flournoy Nancy |
| Pubbl/distr/stampa | Hayward, Calif., : Institute of Mathematical Statistics, c1995 |
| Descrizione fisica | 1 online resource (viii, 288 p. ) : ill. ; |
| Disciplina | 519.5/38 |
| Altri autori (Persone) |
FlournoyNancy <1947->
RosenbergerWilliam F |
| Collana | Institute of Mathematical Statistics lecture notes-monograph series |
| Soggetto topico | Experimental design |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910482887403321 |
Flournoy Nancy
|
||
| Hayward, Calif., : Institute of Mathematical Statistics, c1995 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Adaptive designs : selected proceedings of a 1992 joint AMS-IMS-SIAM summer conference / / Nancy Flournoy and William F. Rosenberger, editors [[electronic resource]]
| Adaptive designs : selected proceedings of a 1992 joint AMS-IMS-SIAM summer conference / / Nancy Flournoy and William F. Rosenberger, editors [[electronic resource]] |
| Autore | Flournoy Nancy |
| Pubbl/distr/stampa | Hayward, Calif., : Institute of Mathematical Statistics, c1995 |
| Descrizione fisica | 1 online resource (viii, 288 p. ) : ill. ; |
| Disciplina | 519.5/38 |
| Altri autori (Persone) |
FlournoyNancy <1947->
RosenbergerWilliam F |
| Collana | Institute of Mathematical Statistics lecture notes-monograph series |
| Soggetto topico | Experimental design |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996210821303316 |
|
Flournoy Nancy
|
||
| Hayward, Calif., : Institute of Mathematical Statistics, c1995 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
The theory of response-adaptive randomization in clinical trials [[electronic resource] /] / Feifang Hu, William F. Rosenberger
| The theory of response-adaptive randomization in clinical trials [[electronic resource] /] / Feifang Hu, William F. Rosenberger |
| Autore | Hu Feifang <1964-> |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley-Interscience, c2006 |
| Descrizione fisica | 1 online resource (234 p.) |
| Disciplina | 610.724 |
| Altri autori (Persone) | RosenbergerWilliam F |
| Collana | Wiley Series in Probability and Statistics |
| Soggetto topico | Clinical trials |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-64911-9
9786610649112 0-470-05588-X 0-470-05587-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
The Theory of Response-Adaptive Randomization in Clinical Trials; Dedication; Contents; Preface; 1 Introduction; 1.1 Randomization in clinical trials; 1.1.1 Complete randomization; 1.1.2 Restricted randomization procedures; 1.1.3 Response-adaptive randomization procedures; 1.1.4 Covariate-adaptive randomization procedures; 1.1.5 Covariate-adjusted response-adaptive randomization procedures; 1.2 Response-adaptive randomization in a historical context; 1.3 Outline of the book; 1.4 References; 2 Fundamental Questions of Response-Adaptive Randomization; 2.1 Optimal allocation
2.2 The relationship between power and response-adaptive randomization2.3 The relationship for K > 2 treatments; 2.4 Asymptotically best procedures; 2.5 References; 3 Likelihood-Based Inference; 3.1 Data structure and likelihood; 3.2 Asymptotic properties of maximum likelihood estimators; 3.3 The general result for determining asymptotically best procedures; 3.4 Conclusions; 3.5 References; 4 Procedures Based on Urn Models; 4.1 Generalized Friedman 's urn; 4.1.1 Historical results on asymptotic properties; 4.1.2 Assumptions and notation; 4.1.3 Main asymptotic theorems; 4.1.4 Some examples 4.1.5 Proving the main theoretical results4.2 The class of ternary urn models; 4.2.1 Randomized Pólya urn; 4.2.2 Birth and death urn; 4.2.3 Drop-the-loser rule; 4.2.4 Generalized drop-the-loser rule; 4.2.5 Asymptotic properties of the GDL rule; 4.3 References; 5 Procedures Based on Sequential Estimation; 5.1 Examples; 5.2 Properties of procedures based on sequential estimation for K = 2; 5.3 Notation and conditions for the general framework; 5.4 Asymptotic results and some examples; 5.5 Proving the main theorems; 5.6 References; 6 Sample Size Calculation 6.1 Power of a randomization procedure6.2 Three types of sample size; 6.3 Examples; 6.3.1 Restricted randomization; 6.3.2 Response-adaptive randomization; 6.4 References; 7 Additional Considerations; 7. 1 The effects of delayed response; 7.2 Continuous responses; 7.2.1 Asymptotic variance of the four procedures; 7.3 Multiple (K > 2) treatments; 7.4 Accommodating heterogeneity; 7.4.1 Heterogeneity based on time trends; 7.4.2 Heterogeneity based on covariates; 7.4.3 Statistical inference under heterogeneity; 7.5 References; 8 Implications for the Practice of Clinical Trials; 8.1 Standards 8.2 Binary responses8.3 Continuous responses; 8.4 The effects of delayed response; 8.5 Conclusions; 8.6 References; 9 Incorporating Covariates; 9.1 Introduction and examples; 9.1.1 Covariate-adaptive randomization procedures; 9.1.2 CARA Randomization Procedures; 9.2 General framework and asymptotic results; 9.2.1 The procedure for K treatments; 9.2.2 Main theoretical results; 9.3 Generalized linear models; 9.4 Two treatments with binary responses; 9.4.1 Power; 9.5 Conclusions; 9.6 References; 10 Conclusions and Open Problems; 10.1 Conclusions; 10.2 Open problems; 10.3 References Appendix A: Supporting Technical Material |
| Record Nr. | UNINA-9910143567603321 |
|
Hu Feifang <1964->
|
||
| Hoboken, N.J., : Wiley-Interscience, c2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The theory of response-adaptive randomization in clinical trials [[electronic resource] /] / Feifang Hu, William F. Rosenberger
| The theory of response-adaptive randomization in clinical trials [[electronic resource] /] / Feifang Hu, William F. Rosenberger |
| Autore | Hu Feifang <1964-> |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley-Interscience, c2006 |
| Descrizione fisica | 1 online resource (234 p.) |
| Disciplina | 610.724 |
| Altri autori (Persone) | RosenbergerWilliam F |
| Collana | Wiley Series in Probability and Statistics |
| Soggetto topico | Clinical trials |
| ISBN |
1-280-64911-9
9786610649112 0-470-05588-X 0-470-05587-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
The Theory of Response-Adaptive Randomization in Clinical Trials; Dedication; Contents; Preface; 1 Introduction; 1.1 Randomization in clinical trials; 1.1.1 Complete randomization; 1.1.2 Restricted randomization procedures; 1.1.3 Response-adaptive randomization procedures; 1.1.4 Covariate-adaptive randomization procedures; 1.1.5 Covariate-adjusted response-adaptive randomization procedures; 1.2 Response-adaptive randomization in a historical context; 1.3 Outline of the book; 1.4 References; 2 Fundamental Questions of Response-Adaptive Randomization; 2.1 Optimal allocation
2.2 The relationship between power and response-adaptive randomization2.3 The relationship for K > 2 treatments; 2.4 Asymptotically best procedures; 2.5 References; 3 Likelihood-Based Inference; 3.1 Data structure and likelihood; 3.2 Asymptotic properties of maximum likelihood estimators; 3.3 The general result for determining asymptotically best procedures; 3.4 Conclusions; 3.5 References; 4 Procedures Based on Urn Models; 4.1 Generalized Friedman 's urn; 4.1.1 Historical results on asymptotic properties; 4.1.2 Assumptions and notation; 4.1.3 Main asymptotic theorems; 4.1.4 Some examples 4.1.5 Proving the main theoretical results4.2 The class of ternary urn models; 4.2.1 Randomized Pólya urn; 4.2.2 Birth and death urn; 4.2.3 Drop-the-loser rule; 4.2.4 Generalized drop-the-loser rule; 4.2.5 Asymptotic properties of the GDL rule; 4.3 References; 5 Procedures Based on Sequential Estimation; 5.1 Examples; 5.2 Properties of procedures based on sequential estimation for K = 2; 5.3 Notation and conditions for the general framework; 5.4 Asymptotic results and some examples; 5.5 Proving the main theorems; 5.6 References; 6 Sample Size Calculation 6.1 Power of a randomization procedure6.2 Three types of sample size; 6.3 Examples; 6.3.1 Restricted randomization; 6.3.2 Response-adaptive randomization; 6.4 References; 7 Additional Considerations; 7. 1 The effects of delayed response; 7.2 Continuous responses; 7.2.1 Asymptotic variance of the four procedures; 7.3 Multiple (K > 2) treatments; 7.4 Accommodating heterogeneity; 7.4.1 Heterogeneity based on time trends; 7.4.2 Heterogeneity based on covariates; 7.4.3 Statistical inference under heterogeneity; 7.5 References; 8 Implications for the Practice of Clinical Trials; 8.1 Standards 8.2 Binary responses8.3 Continuous responses; 8.4 The effects of delayed response; 8.5 Conclusions; 8.6 References; 9 Incorporating Covariates; 9.1 Introduction and examples; 9.1.1 Covariate-adaptive randomization procedures; 9.1.2 CARA Randomization Procedures; 9.2 General framework and asymptotic results; 9.2.1 The procedure for K treatments; 9.2.2 Main theoretical results; 9.3 Generalized linear models; 9.4 Two treatments with binary responses; 9.4.1 Power; 9.5 Conclusions; 9.6 References; 10 Conclusions and Open Problems; 10.1 Conclusions; 10.2 Open problems; 10.3 References Appendix A: Supporting Technical Material |
| Record Nr. | UNINA-9910829907703321 |
|
Hu Feifang <1964->
|
||
| Hoboken, N.J., : Wiley-Interscience, c2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The theory of response-adaptive randomization in clinical trials [[electronic resource] /] / Feifang Hu, William F. Rosenberger
| The theory of response-adaptive randomization in clinical trials [[electronic resource] /] / Feifang Hu, William F. Rosenberger |
| Autore | Hu Feifang <1964-> |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley-Interscience, c2006 |
| Descrizione fisica | 1 online resource (234 p.) |
| Disciplina | 610.724 |
| Altri autori (Persone) | RosenbergerWilliam F |
| Collana | Wiley Series in Probability and Statistics |
| Soggetto topico | Clinical trials |
| ISBN |
1-280-64911-9
9786610649112 0-470-05588-X 0-470-05587-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
The Theory of Response-Adaptive Randomization in Clinical Trials; Dedication; Contents; Preface; 1 Introduction; 1.1 Randomization in clinical trials; 1.1.1 Complete randomization; 1.1.2 Restricted randomization procedures; 1.1.3 Response-adaptive randomization procedures; 1.1.4 Covariate-adaptive randomization procedures; 1.1.5 Covariate-adjusted response-adaptive randomization procedures; 1.2 Response-adaptive randomization in a historical context; 1.3 Outline of the book; 1.4 References; 2 Fundamental Questions of Response-Adaptive Randomization; 2.1 Optimal allocation
2.2 The relationship between power and response-adaptive randomization2.3 The relationship for K > 2 treatments; 2.4 Asymptotically best procedures; 2.5 References; 3 Likelihood-Based Inference; 3.1 Data structure and likelihood; 3.2 Asymptotic properties of maximum likelihood estimators; 3.3 The general result for determining asymptotically best procedures; 3.4 Conclusions; 3.5 References; 4 Procedures Based on Urn Models; 4.1 Generalized Friedman 's urn; 4.1.1 Historical results on asymptotic properties; 4.1.2 Assumptions and notation; 4.1.3 Main asymptotic theorems; 4.1.4 Some examples 4.1.5 Proving the main theoretical results4.2 The class of ternary urn models; 4.2.1 Randomized Pólya urn; 4.2.2 Birth and death urn; 4.2.3 Drop-the-loser rule; 4.2.4 Generalized drop-the-loser rule; 4.2.5 Asymptotic properties of the GDL rule; 4.3 References; 5 Procedures Based on Sequential Estimation; 5.1 Examples; 5.2 Properties of procedures based on sequential estimation for K = 2; 5.3 Notation and conditions for the general framework; 5.4 Asymptotic results and some examples; 5.5 Proving the main theorems; 5.6 References; 6 Sample Size Calculation 6.1 Power of a randomization procedure6.2 Three types of sample size; 6.3 Examples; 6.3.1 Restricted randomization; 6.3.2 Response-adaptive randomization; 6.4 References; 7 Additional Considerations; 7. 1 The effects of delayed response; 7.2 Continuous responses; 7.2.1 Asymptotic variance of the four procedures; 7.3 Multiple (K > 2) treatments; 7.4 Accommodating heterogeneity; 7.4.1 Heterogeneity based on time trends; 7.4.2 Heterogeneity based on covariates; 7.4.3 Statistical inference under heterogeneity; 7.5 References; 8 Implications for the Practice of Clinical Trials; 8.1 Standards 8.2 Binary responses8.3 Continuous responses; 8.4 The effects of delayed response; 8.5 Conclusions; 8.6 References; 9 Incorporating Covariates; 9.1 Introduction and examples; 9.1.1 Covariate-adaptive randomization procedures; 9.1.2 CARA Randomization Procedures; 9.2 General framework and asymptotic results; 9.2.1 The procedure for K treatments; 9.2.2 Main theoretical results; 9.3 Generalized linear models; 9.4 Two treatments with binary responses; 9.4.1 Power; 9.5 Conclusions; 9.6 References; 10 Conclusions and Open Problems; 10.1 Conclusions; 10.2 Open problems; 10.3 References Appendix A: Supporting Technical Material |
| Record Nr. | UNINA-9910841503203321 |
|
Hu Feifang <1964->
|
||
| Hoboken, N.J., : Wiley-Interscience, c2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||