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Advanced vaccine research : methods for the decade of vaccines / / edited by Fabio Bagnoli and Rino Rappuoli
| Advanced vaccine research : methods for the decade of vaccines / / edited by Fabio Bagnoli and Rino Rappuoli |
| Pubbl/distr/stampa | Norfolk, England : , : Caister Academic Press, , [2015] |
| Descrizione fisica | 1 online resource (474 p.) |
| Disciplina | 615.372 |
| Soggetto topico |
Vaccines - Research
Drug development |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-910190-04-7 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; Contributors; Current Books of Interest; Preface; Part I: Innovative Technologies and Approaches in Vaccine Research; 1: Deep Sequencing in Vaccine Research, Development and Surveillance ; Impact of DNA sequencing on vaccines research and development; Deep sequencing potential to transform vaccinology; 2: New Bioinformatics Algorithms Applied to Deep Sequencing Projects ; Introduction; Better understating of host and pathogen genomes; Computational approaches to study adaptive immune responses; Better understanding of transcriptome
Epigenomics: understanding of inheritable chemical changesMetagenomics: finding new pathogens and strains; Bioinformatics challenges; 3: Comparative Genomics Approaches for Tracking the Emergence and Spread of Disease-associated Bacteria; Background; Comparative genomics of disease-associated bacteria; Assays for identification of disease-associated bacteria based on insights from comparative genomics; Conclusions; 4: Quantitative Proteomics in Vaccine Research; Introduction; Quantitative proteomics based on gel electrophoresis; Quantitative proteomics based on differential mass tag Label-free technologies and targeted proteomicsMass spectrometry for viral vaccinology; Proteomic technology for vaccine development ; Combining proteomics and system biology to improve vaccines; Concluding remarks; 5: Structural Biology in Vaccine Research; Introduction; Experimental mapping and computational prediction of epitopes; Examples of structural vaccinology for bacterial and viral pathogens; Concluding remarks and future directions; 6: Cellular Screens to Interrogate the Human T- and B-cell Repertoires and Design Better Vaccines ; Introduction Generation of naive B- and T-cell repertoires7: Novel Strategies of Vaccine Administration: The Science Behind Epidermal and Dermal Immunization; Introduction; The skin layers; Skin antigen-presenting cells and other players in vaccination; Principles and methods in skin immunization; Vaccine formulation and immunity; Immunological advantage of epidermal and dermal immunization; 8: Toll-like Receptors as Targets to Develop Novel Adjuvants; Introduction; Innate immunity; TLR-based adjuvants in high-priority vaccines; Lessons learned from studies of TLR agonists as adjuvants Safety considerations of TLR agonistsChallenges for the next decade; 9: The Importance of Cell-mediated Immunity for Bacterial Vaccines ; Introduction; T-cell responses to bacterial infection; Targeting cellular immunity for novel anti-bacterial vaccine design; 10: T-cell-inducing Vaccines; Introduction; How can we measure T-cell responses?; Technologies for inducing T-cell responses by vaccination; Heterologous prime-boost immunization; Successful clinical development of T-cell vaccines; 11: Exploiting the Mutanome for Personalized Cancer Immunotherapy Cancer mutations as therapeutic targets |
| Record Nr. | UNINA-9910460918103321 |
| Norfolk, England : , : Caister Academic Press, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Advanced vaccine research : methods for the decade of vaccines / / edited by Fabio Bagnoli and Rino Rappuoli
| Advanced vaccine research : methods for the decade of vaccines / / edited by Fabio Bagnoli and Rino Rappuoli |
| Pubbl/distr/stampa | Norfolk, England : , : Caister Academic Press, , [2015] |
| Descrizione fisica | 1 online resource (474 p.) |
| Disciplina | 615.372 |
| Soggetto topico |
Vaccines - Research
Drug development |
| ISBN | 1-910190-04-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; Contributors; Current Books of Interest; Preface; Part I: Innovative Technologies and Approaches in Vaccine Research; 1: Deep Sequencing in Vaccine Research, Development and Surveillance ; Impact of DNA sequencing on vaccines research and development; Deep sequencing potential to transform vaccinology; 2: New Bioinformatics Algorithms Applied to Deep Sequencing Projects ; Introduction; Better understating of host and pathogen genomes; Computational approaches to study adaptive immune responses; Better understanding of transcriptome
Epigenomics: understanding of inheritable chemical changesMetagenomics: finding new pathogens and strains; Bioinformatics challenges; 3: Comparative Genomics Approaches for Tracking the Emergence and Spread of Disease-associated Bacteria; Background; Comparative genomics of disease-associated bacteria; Assays for identification of disease-associated bacteria based on insights from comparative genomics; Conclusions; 4: Quantitative Proteomics in Vaccine Research; Introduction; Quantitative proteomics based on gel electrophoresis; Quantitative proteomics based on differential mass tag Label-free technologies and targeted proteomicsMass spectrometry for viral vaccinology; Proteomic technology for vaccine development ; Combining proteomics and system biology to improve vaccines; Concluding remarks; 5: Structural Biology in Vaccine Research; Introduction; Experimental mapping and computational prediction of epitopes; Examples of structural vaccinology for bacterial and viral pathogens; Concluding remarks and future directions; 6: Cellular Screens to Interrogate the Human T- and B-cell Repertoires and Design Better Vaccines ; Introduction Generation of naive B- and T-cell repertoires7: Novel Strategies of Vaccine Administration: The Science Behind Epidermal and Dermal Immunization; Introduction; The skin layers; Skin antigen-presenting cells and other players in vaccination; Principles and methods in skin immunization; Vaccine formulation and immunity; Immunological advantage of epidermal and dermal immunization; 8: Toll-like Receptors as Targets to Develop Novel Adjuvants; Introduction; Innate immunity; TLR-based adjuvants in high-priority vaccines; Lessons learned from studies of TLR agonists as adjuvants Safety considerations of TLR agonistsChallenges for the next decade; 9: The Importance of Cell-mediated Immunity for Bacterial Vaccines ; Introduction; T-cell responses to bacterial infection; Targeting cellular immunity for novel anti-bacterial vaccine design; 10: T-cell-inducing Vaccines; Introduction; How can we measure T-cell responses?; Technologies for inducing T-cell responses by vaccination; Heterologous prime-boost immunization; Successful clinical development of T-cell vaccines; 11: Exploiting the Mutanome for Personalized Cancer Immunotherapy Cancer mutations as therapeutic targets |
| Record Nr. | UNINA-9910787429503321 |
| Norfolk, England : , : Caister Academic Press, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Advanced vaccine research : methods for the decade of vaccines / / edited by Fabio Bagnoli and Rino Rappuoli
| Advanced vaccine research : methods for the decade of vaccines / / edited by Fabio Bagnoli and Rino Rappuoli |
| Pubbl/distr/stampa | Norfolk, England : , : Caister Academic Press, , [2015] |
| Descrizione fisica | 1 online resource (474 p.) |
| Disciplina | 615.372 |
| Soggetto topico |
Vaccines - Research
Drug development |
| ISBN | 1-910190-04-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; Contributors; Current Books of Interest; Preface; Part I: Innovative Technologies and Approaches in Vaccine Research; 1: Deep Sequencing in Vaccine Research, Development and Surveillance ; Impact of DNA sequencing on vaccines research and development; Deep sequencing potential to transform vaccinology; 2: New Bioinformatics Algorithms Applied to Deep Sequencing Projects ; Introduction; Better understating of host and pathogen genomes; Computational approaches to study adaptive immune responses; Better understanding of transcriptome
Epigenomics: understanding of inheritable chemical changesMetagenomics: finding new pathogens and strains; Bioinformatics challenges; 3: Comparative Genomics Approaches for Tracking the Emergence and Spread of Disease-associated Bacteria; Background; Comparative genomics of disease-associated bacteria; Assays for identification of disease-associated bacteria based on insights from comparative genomics; Conclusions; 4: Quantitative Proteomics in Vaccine Research; Introduction; Quantitative proteomics based on gel electrophoresis; Quantitative proteomics based on differential mass tag Label-free technologies and targeted proteomicsMass spectrometry for viral vaccinology; Proteomic technology for vaccine development ; Combining proteomics and system biology to improve vaccines; Concluding remarks; 5: Structural Biology in Vaccine Research; Introduction; Experimental mapping and computational prediction of epitopes; Examples of structural vaccinology for bacterial and viral pathogens; Concluding remarks and future directions; 6: Cellular Screens to Interrogate the Human T- and B-cell Repertoires and Design Better Vaccines ; Introduction Generation of naive B- and T-cell repertoires7: Novel Strategies of Vaccine Administration: The Science Behind Epidermal and Dermal Immunization; Introduction; The skin layers; Skin antigen-presenting cells and other players in vaccination; Principles and methods in skin immunization; Vaccine formulation and immunity; Immunological advantage of epidermal and dermal immunization; 8: Toll-like Receptors as Targets to Develop Novel Adjuvants; Introduction; Innate immunity; TLR-based adjuvants in high-priority vaccines; Lessons learned from studies of TLR agonists as adjuvants Safety considerations of TLR agonistsChallenges for the next decade; 9: The Importance of Cell-mediated Immunity for Bacterial Vaccines ; Introduction; T-cell responses to bacterial infection; Targeting cellular immunity for novel anti-bacterial vaccine design; 10: T-cell-inducing Vaccines; Introduction; How can we measure T-cell responses?; Technologies for inducing T-cell responses by vaccination; Heterologous prime-boost immunization; Successful clinical development of T-cell vaccines; 11: Exploiting the Mutanome for Personalized Cancer Immunotherapy Cancer mutations as therapeutic targets |
| Record Nr. | UNINA-9910820979003321 |
| Norfolk, England : , : Caister Academic Press, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Antibodies for infectious diseases / / edited by James E. Crowe, Jr., Diana Boraschi and Rino Rappuoli
| Antibodies for infectious diseases / / edited by James E. Crowe, Jr., Diana Boraschi and Rino Rappuoli |
| Pubbl/distr/stampa | Washington, District of Columbia : , : ASM Press, , 2015 |
| Descrizione fisica | 1 online resource (476 p.) |
| Disciplina | 616.0798 |
| Soggetto topico |
Immunoglobulins
Communicable diseases - Immunological aspects |
| ISBN |
1-68367-340-9
1-68367-098-1 1-55581-741-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Cover ""; ""Half Title ""; ""Title Page ""; ""Copyright ""; ""Contents ""; ""Contr ibutors ""; ""Preface ""; ""INTRODUCTION""; ""Chapter 1: History and Practice: Antibodies in Infectious Diseases""; ""HISTORICAL PERSPECTIVE""; ""INTRODUCTION TO ANTIBODIES""; ""METHODS AND PLATFORMS FOR GENERATING ANTIBODIES""; ""STRATEGIC CONSIDERATIONS IN DEVELOPING ANTIBODY-BASED THERAPIES FOR INFECTIOUS DISEASES""; ""EXAMPLES OF ANTIBODIES THAT ARE OR WERE IN DEVELOPMENT FOR INFECTIOUS DISEASES""; ""FUTURE PERSPECTIVES FOR ANTIBODY TREATMENTS IN INFECTIOUS DISEASES""; ""ACKNOWLEDGMENT""; ""CITATION""
""REFERENCES""""GENERAL FEATURES OF IMMUNOGLOBULINS""; ""Chapter 2: Functions of Antibodies""; ""INTRODUCTION""; ""ANTIBODY FUNCTIONS INDEPENDENT OF EFFECTOR CELLS OR EFFECTOR MOLECULES""; ""INHIBITION OF LATER STEPS""; ""ANTIBODY FUNCTIONS DEPENDENT ON COMPLEMENT""; ""ANTIBODY FUNCTIONS DEPENDENT ON Fc-Fc RECEPTOR INTERACTIONS""; ""OTHER ANTIBODY FUNCTIONS""; ""CONCLUSIONS""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES""; ""Chapter 3: Antibody Structure""; ""BASICS OF ANTIBODY STRUCTURE""; ""CDR H3: SIZE AND SUBTERFUGE""; ""HEAVY CHAIN DOMINATION AND FRAMEWORK CONTACTS"" ""DISULFIDES IN THE CDRs""""SELF-CARBOHYDRATE RECOGNITION: PENETRATING THE GLYCAN SHIELD""; ""UNUSUAL INDELS""; ""MECHANISMS OF ANTIBODY NEUTRALIZATION""; ""SUMMARY""; ""ACKNOWLEDGMENT""; ""CITATION""; ""REFERENCES""; ""Chapter 4: The Role of Complement in Antibody Therapy for Infectious Diseases""; ""INTRODUCTION""; ""COMPLEMENT ACTIVATION""; ""Ab-MEDIATED COMPLEMENT ACTIVATION""; ""EFFECTOR RESPONSES AND THEIR ROLE IN MAb TREATMENTS""; ""MANIPULATING Ab-MEDIATED COMPLEMENT RESPONSES""; ""COMPLEMENT EVASIVE PROPERTIES OF PATHOGENS""; ""CONCLUSIONS AND FUTURE PERSPECTIVE"" ""ACKNOWLEDGMENTS""""CITATION""; ""REFERENCES""; ""Chapter 5: Immunoglobulin E and Allergy: Antibodies in Immune Inflammation and Treatment""; ""IMMUNOLOGICAL MECHANISMS OF ALLERGIC DISEASES AND THE ROLE OF IgE ANTIBODIES""; ""IgE ANTIBODIES IN INFECTIOUS DISEASES""; ""ANTIBODIES IN THE TREATMENT OF ALLERGIES""; ""THE OPPOSITE SIDE OF THE COIN: HARNESSING THE ALLERGIC RESPONSE AGAINST CANCER AND THE EMERGENCE OF ANTIBODIES OF THE IgE CLASS FOR CANCER THERAPY""; ""CONCLUDING REMARKS AND FUTURE ROLES OF ANTIBODIES IN THERAPY""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES"" ""ANTIBODY DISCOVERY APPROACHES""""Chapter 6: Phage and Yeast Display""; ""DISCOVERY OF THERAPEUTIC ANTIBODIES USING PHAGE DISPLAY TECHNOLOGY""; ""DISCOVERY OF THERAPEUTIC ANTIBODIES USING YEAST DISPLAY TECHNOLOGY""; ""CONCLUSIONS""; ""ACKNOWLEDGMENT""; ""CITATION""; ""REFERENCES""; ""Chapter 7: Efficient Methods To Isolate Human Monoclonal Antibodies from Memory B Cells and Plasma Cells""; ""MANY WAYS TO MAKE HUMAN MONOCLONAL ANTIBODIES""; ""EFFICIENT IMMORTALIZATION OF MEMORY B CELLS BY USING EBV AND CpG"" ""LONG-TERM CULTURE OF SINGLE PLASMA CELLS AND THEIR INTERROGATION USING MULTIPLE ASSAYS"" |
| Record Nr. | UNINA-9910555131903321 |
| Washington, District of Columbia : , : ASM Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Antibodies for infectious diseases / / edited by James E. Crowe, Jr., Diana Boraschi and Rino Rappuoli
| Antibodies for infectious diseases / / edited by James E. Crowe, Jr., Diana Boraschi and Rino Rappuoli |
| Pubbl/distr/stampa | Washington, District of Columbia : , : ASM Press, , 2015 |
| Descrizione fisica | 1 online resource (476 p.) |
| Disciplina | 616.0798 |
| Soggetto topico |
Immunoglobulins
Communicable diseases - Immunological aspects |
| ISBN |
1-68367-340-9
1-68367-098-1 1-55581-741-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Cover ""; ""Half Title ""; ""Title Page ""; ""Copyright ""; ""Contents ""; ""Contr ibutors ""; ""Preface ""; ""INTRODUCTION""; ""Chapter 1: History and Practice: Antibodies in Infectious Diseases""; ""HISTORICAL PERSPECTIVE""; ""INTRODUCTION TO ANTIBODIES""; ""METHODS AND PLATFORMS FOR GENERATING ANTIBODIES""; ""STRATEGIC CONSIDERATIONS IN DEVELOPING ANTIBODY-BASED THERAPIES FOR INFECTIOUS DISEASES""; ""EXAMPLES OF ANTIBODIES THAT ARE OR WERE IN DEVELOPMENT FOR INFECTIOUS DISEASES""; ""FUTURE PERSPECTIVES FOR ANTIBODY TREATMENTS IN INFECTIOUS DISEASES""; ""ACKNOWLEDGMENT""; ""CITATION""
""REFERENCES""""GENERAL FEATURES OF IMMUNOGLOBULINS""; ""Chapter 2: Functions of Antibodies""; ""INTRODUCTION""; ""ANTIBODY FUNCTIONS INDEPENDENT OF EFFECTOR CELLS OR EFFECTOR MOLECULES""; ""INHIBITION OF LATER STEPS""; ""ANTIBODY FUNCTIONS DEPENDENT ON COMPLEMENT""; ""ANTIBODY FUNCTIONS DEPENDENT ON Fc-Fc RECEPTOR INTERACTIONS""; ""OTHER ANTIBODY FUNCTIONS""; ""CONCLUSIONS""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES""; ""Chapter 3: Antibody Structure""; ""BASICS OF ANTIBODY STRUCTURE""; ""CDR H3: SIZE AND SUBTERFUGE""; ""HEAVY CHAIN DOMINATION AND FRAMEWORK CONTACTS"" ""DISULFIDES IN THE CDRs""""SELF-CARBOHYDRATE RECOGNITION: PENETRATING THE GLYCAN SHIELD""; ""UNUSUAL INDELS""; ""MECHANISMS OF ANTIBODY NEUTRALIZATION""; ""SUMMARY""; ""ACKNOWLEDGMENT""; ""CITATION""; ""REFERENCES""; ""Chapter 4: The Role of Complement in Antibody Therapy for Infectious Diseases""; ""INTRODUCTION""; ""COMPLEMENT ACTIVATION""; ""Ab-MEDIATED COMPLEMENT ACTIVATION""; ""EFFECTOR RESPONSES AND THEIR ROLE IN MAb TREATMENTS""; ""MANIPULATING Ab-MEDIATED COMPLEMENT RESPONSES""; ""COMPLEMENT EVASIVE PROPERTIES OF PATHOGENS""; ""CONCLUSIONS AND FUTURE PERSPECTIVE"" ""ACKNOWLEDGMENTS""""CITATION""; ""REFERENCES""; ""Chapter 5: Immunoglobulin E and Allergy: Antibodies in Immune Inflammation and Treatment""; ""IMMUNOLOGICAL MECHANISMS OF ALLERGIC DISEASES AND THE ROLE OF IgE ANTIBODIES""; ""IgE ANTIBODIES IN INFECTIOUS DISEASES""; ""ANTIBODIES IN THE TREATMENT OF ALLERGIES""; ""THE OPPOSITE SIDE OF THE COIN: HARNESSING THE ALLERGIC RESPONSE AGAINST CANCER AND THE EMERGENCE OF ANTIBODIES OF THE IgE CLASS FOR CANCER THERAPY""; ""CONCLUDING REMARKS AND FUTURE ROLES OF ANTIBODIES IN THERAPY""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES"" ""ANTIBODY DISCOVERY APPROACHES""""Chapter 6: Phage and Yeast Display""; ""DISCOVERY OF THERAPEUTIC ANTIBODIES USING PHAGE DISPLAY TECHNOLOGY""; ""DISCOVERY OF THERAPEUTIC ANTIBODIES USING YEAST DISPLAY TECHNOLOGY""; ""CONCLUSIONS""; ""ACKNOWLEDGMENT""; ""CITATION""; ""REFERENCES""; ""Chapter 7: Efficient Methods To Isolate Human Monoclonal Antibodies from Memory B Cells and Plasma Cells""; ""MANY WAYS TO MAKE HUMAN MONOCLONAL ANTIBODIES""; ""EFFICIENT IMMORTALIZATION OF MEMORY B CELLS BY USING EBV AND CpG"" ""LONG-TERM CULTURE OF SINGLE PLASMA CELLS AND THEIR INTERROGATION USING MULTIPLE ASSAYS"" |
| Record Nr. | UNINA-9910830911403321 |
| Washington, District of Columbia : , : ASM Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Cellular Microbiology / / Pascale Cossart, Patrice Boquet, Staffan Normark, Rino Rappuoli [editors]
| Cellular Microbiology / / Pascale Cossart, Patrice Boquet, Staffan Normark, Rino Rappuoli [editors] |
| Edizione | [Second edition.] |
| Pubbl/distr/stampa | Washington, D.C. : , : ASM Press, , 2005 |
| Descrizione fisica | 1 online resource (xxx, 593 pages) : illustrations |
| Soggetto topico |
Virulence (Microbiology)
Infection Host-bacteria relationships Pathology, Cellular Bacterial genomes |
| ISBN | 1-68367-203-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Microbial pathogens: an overview / Pascale Cossart, Javier Pizarro-Cerda, and Marc Lecuit -- Bacterial human pathogen genomes: an overview / Stephen Bentley [and others] -- Cell biology: an overview / Dana Philpott and Patrice Boquet -- Extracellular matrix and host cell surfaces: potential sites of pathogen interaction / Klaus T. Preissner and G. Singh Chhatwal -- Bacterial adherence to cell surfaces and extracellular matrix / B. Brent Finlay and Michael Caparon -- Molecular basis for cell adhesion and adhesion-mediated signaling / Benjamin Geiger [and others] -- Bacterial signaling to host cells through adhesion molecules and lipid rafts / Guy Tran Van Nhieu, Philippe, J. Sansonetti, and Frank Lafont -- Host cell membrane structure and dynamics / Lynda M. Pierini and Frederick R. Maxfield -- Membrane traffic in the endocytic pathway of eukaryotic cells / Michela Felberbaum-Corti, Raluca Flukiger-Gagescu, and Jean Gruenberg -- Where to stay inside the cell: a homesteader's guide to intracellular parasitism / David G. Russell -- The actin cytoskeleton: regulation of actin filament assembly and disassembly / Frederick S. Southwick -- Bacterial manipulation of the host cell cytoskeleton / Jennifer R. Robbins [and others] -- Bacterial toxins / Mariagrazia Pizza, Vega Masignani, and Rino Rappuoli -- Bacterial protein toxins and tools in cell biology and pharmacology / Klaus Aktories -- Type III secretion systems in animal- and plant-interacting bacteria / Matthew S. Francis [and others] -- Bacterial type IV secretion systems: DNA conjugation machines adapted for export of virulence factors / Peter J. Christie and Antonello Covacci -- Induction of apoptosis by microbial pathogens / Jeremy E. Moss, Ilona Idanpaan-Heikkila, and Arturo Zychlinsky -- Interaction of pathogens with the innate and cellular microbiology adaptive immune system / Emil R. Unanue and Ennio De Gregorio -- Electron microscopy / Chantal de Chastellier -- New tools for virulence gene discovery / Timothy K. McDaniel and Raphael H. Valdivia -- Genome-wide approaches to studying prokaryotic biology / Su L. Chiang and Stephen Lory -- Cell biology of virus infection / Mark Marsh -- Use of simple nonvertebrate hosts to model mammalian pathogenesis / Costi D. Sifri and Frederick M. Ausubel. |
| Record Nr. | UNINA-9910876873303321 |
| Washington, D.C. : , : ASM Press, , 2005 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Human Challenge Studies for Vaccine Development / / edited by Fabio Bagnoli, Giuseppe Del Giudice, Sanjay K. Phogat, Rino Rappuoli
| Human Challenge Studies for Vaccine Development / / edited by Fabio Bagnoli, Giuseppe Del Giudice, Sanjay K. Phogat, Rino Rappuoli |
| Autore | Bagnoli Fabio |
| Edizione | [1st ed. 2024.] |
| Pubbl/distr/stampa | Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2024 |
| Descrizione fisica | 1 online resource (380 pages) |
| Disciplina | 615.372 |
| Altri autori (Persone) |
Del GiudiceGiuseppe
PhogatSanjay K RappuoliRino |
| Collana | Current Topics in Microbiology and Immunology |
| Soggetto topico |
Immunology
Medical microbiology Medicine - Research Biology - Research Diseases - Causes and theories of causation Medical Microbiology Translational Research Pathogenesis |
| ISBN | 3-031-63118-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | A brief history of human challenge studies (1900-2021) emphasising the virology, regulatory and ethical requirements, raison d’etre, ethnography, selection of volunteers and unit design -- Regulatory aspects of human challenge studies.-Controlled Human Infection challenge studies with RSV -- Human challenge studies with coronaviruses old and new -- Experimental urethral infection with Neisseria gonorrhoeae -- Helicobacter pylori.-Controlled human infection with Bordetella pertussis Human challenge studies for cholera -- The Controlled Human Infection Model for Enterotoxigenic Escherichia coli -- Challenges in developing a controlled human tuberculosis challenge model -- Shigella Controlled Human Infection Models: Current and Future Perspectives -- The background, role and outline approach for development of a Controlled Human Infection Model for Nontyphoidal Salmonella -- Controlled Human Malaria Infection studies in Africa - past, present, and future -- Controlled infection of humans with the hookworm parasite Necator americanus to accelerate vaccine development. |
| Record Nr. | UNINA-9910899891703321 |
Bagnoli Fabio
|
||
| Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Influenza vaccines for the future [[electronic resource] /] / Rino Rappuoli, Giuseppe Del Giudice, editors
| Influenza vaccines for the future [[electronic resource] /] / Rino Rappuoli, Giuseppe Del Giudice, editors |
| Edizione | [1st ed. 2008.] |
| Pubbl/distr/stampa | Basel ; ; Boston, : Birkhäuser, c2008 |
| Descrizione fisica | 1 online resource (306 p.) |
| Disciplina | 614.5/18 |
| Altri autori (Persone) |
RappuoliRino
Del GiudiceGiuseppe |
| Collana | Birkhäuser advances in infectious diseases |
| Soggetto topico |
Influenza vaccines
Influenza Influenza viruses |
| Soggetto genere / forma | Electronic books. |
| ISBN | 3-7643-8371-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Influenza virus: The biology of a changing virus -- Influenza vaccines have a short but illustrious history -- The epidemiology of influenza and its control -- Influenza and influenza vaccination in children -- The immune response to influenza A viruses -- Correlates of protection against influenza -- The role of animal models in influenza vaccine research -- Live attenuated influenza vaccine -- MF59: A safe and potent oil in water emulsion adjuvant for influenza vaccines, which induces enhanced protection against virus challenge -- Non-recent history of influenza pandemics, vaccines, and adjuvants -- Waiting for a pandemic -- Modeling influenza pandemic and interventions. |
| Record Nr. | UNINA-9910451475703321 |
| Basel ; ; Boston, : Birkhäuser, c2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Influenza vaccines for the future [[electronic resource] /] / Rino Rappuoli, Giuseppe Del Giudice, editors
| Influenza vaccines for the future [[electronic resource] /] / Rino Rappuoli, Giuseppe Del Giudice, editors |
| Edizione | [1st ed. 2008.] |
| Pubbl/distr/stampa | Basel ; ; Boston, : Birkhäuser, c2008 |
| Descrizione fisica | 1 online resource (306 p.) |
| Disciplina | 614.5/18 |
| Altri autori (Persone) |
RappuoliRino
Del GiudiceGiuseppe |
| Collana | Birkhäuser advances in infectious diseases |
| Soggetto topico |
Influenza vaccines
Influenza Influenza viruses |
| ISBN | 3-7643-8371-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Influenza virus: The biology of a changing virus -- Influenza vaccines have a short but illustrious history -- The epidemiology of influenza and its control -- Influenza and influenza vaccination in children -- The immune response to influenza A viruses -- Correlates of protection against influenza -- The role of animal models in influenza vaccine research -- Live attenuated influenza vaccine -- MF59: A safe and potent oil in water emulsion adjuvant for influenza vaccines, which induces enhanced protection against virus challenge -- Non-recent history of influenza pandemics, vaccines, and adjuvants -- Waiting for a pandemic -- Modeling influenza pandemic and interventions. |
| Record Nr. | UNINA-9910782093103321 |
| Basel ; ; Boston, : Birkhäuser, c2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Influenza vaccines for the future / / Rino Rappuoli, Giuseppe Del Giudice, editors
| Influenza vaccines for the future / / Rino Rappuoli, Giuseppe Del Giudice, editors |
| Edizione | [1st ed. 2008.] |
| Pubbl/distr/stampa | Basel ; ; Boston, : Birkhäuser, c2008 |
| Descrizione fisica | 1 online resource (306 p.) |
| Disciplina | 614.5/18 |
| Altri autori (Persone) |
RappuoliRino
Del GiudiceGiuseppe |
| Collana | Birkhäuser advances in infectious diseases |
| Soggetto topico |
Influenza vaccines
Influenza Influenza viruses |
| ISBN | 3-7643-8371-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Influenza virus: The biology of a changing virus -- Influenza vaccines have a short but illustrious history -- The epidemiology of influenza and its control -- Influenza and influenza vaccination in children -- The immune response to influenza A viruses -- Correlates of protection against influenza -- The role of animal models in influenza vaccine research -- Live attenuated influenza vaccine -- MF59: A safe and potent oil in water emulsion adjuvant for influenza vaccines, which induces enhanced protection against virus challenge -- Non-recent history of influenza pandemics, vaccines, and adjuvants -- Waiting for a pandemic -- Modeling influenza pandemic and interventions. |
| Record Nr. | UNINA-9910825152603321 |
| Basel ; ; Boston, : Birkhäuser, c2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
