Advanced vaccine research : methods for the decade of vaccines / / edited by Fabio Bagnoli and Rino Rappuoli |
Pubbl/distr/stampa | Norfolk, England : , : Caister Academic Press, , [2015] |
Descrizione fisica | 1 online resource (474 p.) |
Disciplina | 615.372 |
Soggetto topico |
Vaccines - Research
Drug development |
Soggetto genere / forma | Electronic books. |
ISBN | 1-910190-04-7 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Contents; Contributors; Current Books of Interest; Preface; Part I: Innovative Technologies and Approaches in Vaccine Research; 1: Deep Sequencing in Vaccine Research, Development and Surveillance ; Impact of DNA sequencing on vaccines research and development; Deep sequencing potential to transform vaccinology; 2: New Bioinformatics Algorithms Applied to Deep Sequencing Projects ; Introduction; Better understating of host and pathogen genomes; Computational approaches to study adaptive immune responses; Better understanding of transcriptome
Epigenomics: understanding of inheritable chemical changesMetagenomics: finding new pathogens and strains; Bioinformatics challenges; 3: Comparative Genomics Approaches for Tracking the Emergence and Spread of Disease-associated Bacteria; Background; Comparative genomics of disease-associated bacteria; Assays for identification of disease-associated bacteria based on insights from comparative genomics; Conclusions; 4: Quantitative Proteomics in Vaccine Research; Introduction; Quantitative proteomics based on gel electrophoresis; Quantitative proteomics based on differential mass tag Label-free technologies and targeted proteomicsMass spectrometry for viral vaccinology; Proteomic technology for vaccine development ; Combining proteomics and system biology to improve vaccines; Concluding remarks; 5: Structural Biology in Vaccine Research; Introduction; Experimental mapping and computational prediction of epitopes; Examples of structural vaccinology for bacterial and viral pathogens; Concluding remarks and future directions; 6: Cellular Screens to Interrogate the Human T- and B-cell Repertoires and Design Better Vaccines ; Introduction Generation of naive B- and T-cell repertoires7: Novel Strategies of Vaccine Administration: The Science Behind Epidermal and Dermal Immunization; Introduction; The skin layers; Skin antigen-presenting cells and other players in vaccination; Principles and methods in skin immunization; Vaccine formulation and immunity; Immunological advantage of epidermal and dermal immunization; 8: Toll-like Receptors as Targets to Develop Novel Adjuvants; Introduction; Innate immunity; TLR-based adjuvants in high-priority vaccines; Lessons learned from studies of TLR agonists as adjuvants Safety considerations of TLR agonistsChallenges for the next decade; 9: The Importance of Cell-mediated Immunity for Bacterial Vaccines ; Introduction; T-cell responses to bacterial infection; Targeting cellular immunity for novel anti-bacterial vaccine design; 10: T-cell-inducing Vaccines; Introduction; How can we measure T-cell responses?; Technologies for inducing T-cell responses by vaccination; Heterologous prime-boost immunization; Successful clinical development of T-cell vaccines; 11: Exploiting the Mutanome for Personalized Cancer Immunotherapy Cancer mutations as therapeutic targets |
Record Nr. | UNINA-9910460918103321 |
Norfolk, England : , : Caister Academic Press, , [2015] | ||
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Lo trovi qui: Univ. Federico II | ||
|
Advanced vaccine research : methods for the decade of vaccines / / edited by Fabio Bagnoli and Rino Rappuoli |
Pubbl/distr/stampa | Norfolk, England : , : Caister Academic Press, , [2015] |
Descrizione fisica | 1 online resource (474 p.) |
Disciplina | 615.372 |
Soggetto topico |
Vaccines - Research
Drug development |
ISBN | 1-910190-04-7 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Contents; Contributors; Current Books of Interest; Preface; Part I: Innovative Technologies and Approaches in Vaccine Research; 1: Deep Sequencing in Vaccine Research, Development and Surveillance ; Impact of DNA sequencing on vaccines research and development; Deep sequencing potential to transform vaccinology; 2: New Bioinformatics Algorithms Applied to Deep Sequencing Projects ; Introduction; Better understating of host and pathogen genomes; Computational approaches to study adaptive immune responses; Better understanding of transcriptome
Epigenomics: understanding of inheritable chemical changesMetagenomics: finding new pathogens and strains; Bioinformatics challenges; 3: Comparative Genomics Approaches for Tracking the Emergence and Spread of Disease-associated Bacteria; Background; Comparative genomics of disease-associated bacteria; Assays for identification of disease-associated bacteria based on insights from comparative genomics; Conclusions; 4: Quantitative Proteomics in Vaccine Research; Introduction; Quantitative proteomics based on gel electrophoresis; Quantitative proteomics based on differential mass tag Label-free technologies and targeted proteomicsMass spectrometry for viral vaccinology; Proteomic technology for vaccine development ; Combining proteomics and system biology to improve vaccines; Concluding remarks; 5: Structural Biology in Vaccine Research; Introduction; Experimental mapping and computational prediction of epitopes; Examples of structural vaccinology for bacterial and viral pathogens; Concluding remarks and future directions; 6: Cellular Screens to Interrogate the Human T- and B-cell Repertoires and Design Better Vaccines ; Introduction Generation of naive B- and T-cell repertoires7: Novel Strategies of Vaccine Administration: The Science Behind Epidermal and Dermal Immunization; Introduction; The skin layers; Skin antigen-presenting cells and other players in vaccination; Principles and methods in skin immunization; Vaccine formulation and immunity; Immunological advantage of epidermal and dermal immunization; 8: Toll-like Receptors as Targets to Develop Novel Adjuvants; Introduction; Innate immunity; TLR-based adjuvants in high-priority vaccines; Lessons learned from studies of TLR agonists as adjuvants Safety considerations of TLR agonistsChallenges for the next decade; 9: The Importance of Cell-mediated Immunity for Bacterial Vaccines ; Introduction; T-cell responses to bacterial infection; Targeting cellular immunity for novel anti-bacterial vaccine design; 10: T-cell-inducing Vaccines; Introduction; How can we measure T-cell responses?; Technologies for inducing T-cell responses by vaccination; Heterologous prime-boost immunization; Successful clinical development of T-cell vaccines; 11: Exploiting the Mutanome for Personalized Cancer Immunotherapy Cancer mutations as therapeutic targets |
Record Nr. | UNINA-9910787429503321 |
Norfolk, England : , : Caister Academic Press, , [2015] | ||
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Lo trovi qui: Univ. Federico II | ||
|
Advanced vaccine research : methods for the decade of vaccines / / edited by Fabio Bagnoli and Rino Rappuoli |
Pubbl/distr/stampa | Norfolk, England : , : Caister Academic Press, , [2015] |
Descrizione fisica | 1 online resource (474 p.) |
Disciplina | 615.372 |
Soggetto topico |
Vaccines - Research
Drug development |
ISBN | 1-910190-04-7 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Contents; Contributors; Current Books of Interest; Preface; Part I: Innovative Technologies and Approaches in Vaccine Research; 1: Deep Sequencing in Vaccine Research, Development and Surveillance ; Impact of DNA sequencing on vaccines research and development; Deep sequencing potential to transform vaccinology; 2: New Bioinformatics Algorithms Applied to Deep Sequencing Projects ; Introduction; Better understating of host and pathogen genomes; Computational approaches to study adaptive immune responses; Better understanding of transcriptome
Epigenomics: understanding of inheritable chemical changesMetagenomics: finding new pathogens and strains; Bioinformatics challenges; 3: Comparative Genomics Approaches for Tracking the Emergence and Spread of Disease-associated Bacteria; Background; Comparative genomics of disease-associated bacteria; Assays for identification of disease-associated bacteria based on insights from comparative genomics; Conclusions; 4: Quantitative Proteomics in Vaccine Research; Introduction; Quantitative proteomics based on gel electrophoresis; Quantitative proteomics based on differential mass tag Label-free technologies and targeted proteomicsMass spectrometry for viral vaccinology; Proteomic technology for vaccine development ; Combining proteomics and system biology to improve vaccines; Concluding remarks; 5: Structural Biology in Vaccine Research; Introduction; Experimental mapping and computational prediction of epitopes; Examples of structural vaccinology for bacterial and viral pathogens; Concluding remarks and future directions; 6: Cellular Screens to Interrogate the Human T- and B-cell Repertoires and Design Better Vaccines ; Introduction Generation of naive B- and T-cell repertoires7: Novel Strategies of Vaccine Administration: The Science Behind Epidermal and Dermal Immunization; Introduction; The skin layers; Skin antigen-presenting cells and other players in vaccination; Principles and methods in skin immunization; Vaccine formulation and immunity; Immunological advantage of epidermal and dermal immunization; 8: Toll-like Receptors as Targets to Develop Novel Adjuvants; Introduction; Innate immunity; TLR-based adjuvants in high-priority vaccines; Lessons learned from studies of TLR agonists as adjuvants Safety considerations of TLR agonistsChallenges for the next decade; 9: The Importance of Cell-mediated Immunity for Bacterial Vaccines ; Introduction; T-cell responses to bacterial infection; Targeting cellular immunity for novel anti-bacterial vaccine design; 10: T-cell-inducing Vaccines; Introduction; How can we measure T-cell responses?; Technologies for inducing T-cell responses by vaccination; Heterologous prime-boost immunization; Successful clinical development of T-cell vaccines; 11: Exploiting the Mutanome for Personalized Cancer Immunotherapy Cancer mutations as therapeutic targets |
Record Nr. | UNINA-9910820979003321 |
Norfolk, England : , : Caister Academic Press, , [2015] | ||
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Lo trovi qui: Univ. Federico II | ||
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Antibodies for infectious diseases / / edited by James E. Crowe, Jr., Diana Boraschi and Rino Rappuoli |
Pubbl/distr/stampa | Washington, District of Columbia : , : ASM Press, , 2015 |
Descrizione fisica | 1 online resource (476 p.) |
Disciplina | 616.0798 |
Soggetto topico |
Immunoglobulins
Communicable diseases - Immunological aspects |
ISBN |
1-68367-340-9
1-68367-098-1 1-55581-741-6 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
""Cover ""; ""Half Title ""; ""Title Page ""; ""Copyright ""; ""Contents ""; ""Contr ibutors ""; ""Preface ""; ""INTRODUCTION""; ""Chapter 1: History and Practice: Antibodies in Infectious Diseases""; ""HISTORICAL PERSPECTIVE""; ""INTRODUCTION TO ANTIBODIES""; ""METHODS AND PLATFORMS FOR GENERATING ANTIBODIES""; ""STRATEGIC CONSIDERATIONS IN DEVELOPING ANTIBODY-BASED THERAPIES FOR INFECTIOUS DISEASES""; ""EXAMPLES OF ANTIBODIES THAT ARE OR WERE IN DEVELOPMENT FOR INFECTIOUS DISEASES""; ""FUTURE PERSPECTIVES FOR ANTIBODY TREATMENTS IN INFECTIOUS DISEASES""; ""ACKNOWLEDGMENT""; ""CITATION""
""REFERENCES""""GENERAL FEATURES OF IMMUNOGLOBULINS""; ""Chapter 2: Functions of Antibodies""; ""INTRODUCTION""; ""ANTIBODY FUNCTIONS INDEPENDENT OF EFFECTOR CELLS OR EFFECTOR MOLECULES""; ""INHIBITION OF LATER STEPS""; ""ANTIBODY FUNCTIONS DEPENDENT ON COMPLEMENT""; ""ANTIBODY FUNCTIONS DEPENDENT ON Fc-Fc RECEPTOR INTERACTIONS""; ""OTHER ANTIBODY FUNCTIONS""; ""CONCLUSIONS""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES""; ""Chapter 3: Antibody Structure""; ""BASICS OF ANTIBODY STRUCTURE""; ""CDR H3: SIZE AND SUBTERFUGE""; ""HEAVY CHAIN DOMINATION AND FRAMEWORK CONTACTS"" ""DISULFIDES IN THE CDRs""""SELF-CARBOHYDRATE RECOGNITION: PENETRATING THE GLYCAN SHIELD""; ""UNUSUAL INDELS""; ""MECHANISMS OF ANTIBODY NEUTRALIZATION""; ""SUMMARY""; ""ACKNOWLEDGMENT""; ""CITATION""; ""REFERENCES""; ""Chapter 4: The Role of Complement in Antibody Therapy for Infectious Diseases""; ""INTRODUCTION""; ""COMPLEMENT ACTIVATION""; ""Ab-MEDIATED COMPLEMENT ACTIVATION""; ""EFFECTOR RESPONSES AND THEIR ROLE IN MAb TREATMENTS""; ""MANIPULATING Ab-MEDIATED COMPLEMENT RESPONSES""; ""COMPLEMENT EVASIVE PROPERTIES OF PATHOGENS""; ""CONCLUSIONS AND FUTURE PERSPECTIVE"" ""ACKNOWLEDGMENTS""""CITATION""; ""REFERENCES""; ""Chapter 5: Immunoglobulin E and Allergy: Antibodies in Immune Inflammation and Treatment""; ""IMMUNOLOGICAL MECHANISMS OF ALLERGIC DISEASES AND THE ROLE OF IgE ANTIBODIES""; ""IgE ANTIBODIES IN INFECTIOUS DISEASES""; ""ANTIBODIES IN THE TREATMENT OF ALLERGIES""; ""THE OPPOSITE SIDE OF THE COIN: HARNESSING THE ALLERGIC RESPONSE AGAINST CANCER AND THE EMERGENCE OF ANTIBODIES OF THE IgE CLASS FOR CANCER THERAPY""; ""CONCLUDING REMARKS AND FUTURE ROLES OF ANTIBODIES IN THERAPY""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES"" ""ANTIBODY DISCOVERY APPROACHES""""Chapter 6: Phage and Yeast Display""; ""DISCOVERY OF THERAPEUTIC ANTIBODIES USING PHAGE DISPLAY TECHNOLOGY""; ""DISCOVERY OF THERAPEUTIC ANTIBODIES USING YEAST DISPLAY TECHNOLOGY""; ""CONCLUSIONS""; ""ACKNOWLEDGMENT""; ""CITATION""; ""REFERENCES""; ""Chapter 7: Efficient Methods To Isolate Human Monoclonal Antibodies from Memory B Cells and Plasma Cells""; ""MANY WAYS TO MAKE HUMAN MONOCLONAL ANTIBODIES""; ""EFFICIENT IMMORTALIZATION OF MEMORY B CELLS BY USING EBV AND CpG"" ""LONG-TERM CULTURE OF SINGLE PLASMA CELLS AND THEIR INTERROGATION USING MULTIPLE ASSAYS"" |
Record Nr. | UNINA-9910555131903321 |
Washington, District of Columbia : , : ASM Press, , 2015 | ||
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Lo trovi qui: Univ. Federico II | ||
|
Antibodies for infectious diseases / / edited by James E. Crowe, Jr., Diana Boraschi and Rino Rappuoli |
Pubbl/distr/stampa | Washington, District of Columbia : , : ASM Press, , 2015 |
Descrizione fisica | 1 online resource (476 p.) |
Disciplina | 616.0798 |
Soggetto topico |
Immunoglobulins
Communicable diseases - Immunological aspects |
ISBN |
1-68367-340-9
1-68367-098-1 1-55581-741-6 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
""Cover ""; ""Half Title ""; ""Title Page ""; ""Copyright ""; ""Contents ""; ""Contr ibutors ""; ""Preface ""; ""INTRODUCTION""; ""Chapter 1: History and Practice: Antibodies in Infectious Diseases""; ""HISTORICAL PERSPECTIVE""; ""INTRODUCTION TO ANTIBODIES""; ""METHODS AND PLATFORMS FOR GENERATING ANTIBODIES""; ""STRATEGIC CONSIDERATIONS IN DEVELOPING ANTIBODY-BASED THERAPIES FOR INFECTIOUS DISEASES""; ""EXAMPLES OF ANTIBODIES THAT ARE OR WERE IN DEVELOPMENT FOR INFECTIOUS DISEASES""; ""FUTURE PERSPECTIVES FOR ANTIBODY TREATMENTS IN INFECTIOUS DISEASES""; ""ACKNOWLEDGMENT""; ""CITATION""
""REFERENCES""""GENERAL FEATURES OF IMMUNOGLOBULINS""; ""Chapter 2: Functions of Antibodies""; ""INTRODUCTION""; ""ANTIBODY FUNCTIONS INDEPENDENT OF EFFECTOR CELLS OR EFFECTOR MOLECULES""; ""INHIBITION OF LATER STEPS""; ""ANTIBODY FUNCTIONS DEPENDENT ON COMPLEMENT""; ""ANTIBODY FUNCTIONS DEPENDENT ON Fc-Fc RECEPTOR INTERACTIONS""; ""OTHER ANTIBODY FUNCTIONS""; ""CONCLUSIONS""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES""; ""Chapter 3: Antibody Structure""; ""BASICS OF ANTIBODY STRUCTURE""; ""CDR H3: SIZE AND SUBTERFUGE""; ""HEAVY CHAIN DOMINATION AND FRAMEWORK CONTACTS"" ""DISULFIDES IN THE CDRs""""SELF-CARBOHYDRATE RECOGNITION: PENETRATING THE GLYCAN SHIELD""; ""UNUSUAL INDELS""; ""MECHANISMS OF ANTIBODY NEUTRALIZATION""; ""SUMMARY""; ""ACKNOWLEDGMENT""; ""CITATION""; ""REFERENCES""; ""Chapter 4: The Role of Complement in Antibody Therapy for Infectious Diseases""; ""INTRODUCTION""; ""COMPLEMENT ACTIVATION""; ""Ab-MEDIATED COMPLEMENT ACTIVATION""; ""EFFECTOR RESPONSES AND THEIR ROLE IN MAb TREATMENTS""; ""MANIPULATING Ab-MEDIATED COMPLEMENT RESPONSES""; ""COMPLEMENT EVASIVE PROPERTIES OF PATHOGENS""; ""CONCLUSIONS AND FUTURE PERSPECTIVE"" ""ACKNOWLEDGMENTS""""CITATION""; ""REFERENCES""; ""Chapter 5: Immunoglobulin E and Allergy: Antibodies in Immune Inflammation and Treatment""; ""IMMUNOLOGICAL MECHANISMS OF ALLERGIC DISEASES AND THE ROLE OF IgE ANTIBODIES""; ""IgE ANTIBODIES IN INFECTIOUS DISEASES""; ""ANTIBODIES IN THE TREATMENT OF ALLERGIES""; ""THE OPPOSITE SIDE OF THE COIN: HARNESSING THE ALLERGIC RESPONSE AGAINST CANCER AND THE EMERGENCE OF ANTIBODIES OF THE IgE CLASS FOR CANCER THERAPY""; ""CONCLUDING REMARKS AND FUTURE ROLES OF ANTIBODIES IN THERAPY""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES"" ""ANTIBODY DISCOVERY APPROACHES""""Chapter 6: Phage and Yeast Display""; ""DISCOVERY OF THERAPEUTIC ANTIBODIES USING PHAGE DISPLAY TECHNOLOGY""; ""DISCOVERY OF THERAPEUTIC ANTIBODIES USING YEAST DISPLAY TECHNOLOGY""; ""CONCLUSIONS""; ""ACKNOWLEDGMENT""; ""CITATION""; ""REFERENCES""; ""Chapter 7: Efficient Methods To Isolate Human Monoclonal Antibodies from Memory B Cells and Plasma Cells""; ""MANY WAYS TO MAKE HUMAN MONOCLONAL ANTIBODIES""; ""EFFICIENT IMMORTALIZATION OF MEMORY B CELLS BY USING EBV AND CpG"" ""LONG-TERM CULTURE OF SINGLE PLASMA CELLS AND THEIR INTERROGATION USING MULTIPLE ASSAYS"" |
Record Nr. | UNINA-9910830911403321 |
Washington, District of Columbia : , : ASM Press, , 2015 | ||
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Lo trovi qui: Univ. Federico II | ||
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Influenza vaccines for the future [[electronic resource] /] / Rino Rappuoli, Giuseppe Del Giudice, editors |
Edizione | [1st ed. 2008.] |
Pubbl/distr/stampa | Basel ; ; Boston, : Birkhäuser, c2008 |
Descrizione fisica | 1 online resource (306 p.) |
Disciplina | 614.5/18 |
Altri autori (Persone) |
RappuoliRino
Del GiudiceGiuseppe |
Collana | Birkhäuser advances in infectious diseases |
Soggetto topico |
Influenza vaccines
Influenza Influenza viruses |
Soggetto genere / forma | Electronic books. |
ISBN | 3-7643-8371-2 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Influenza virus: The biology of a changing virus -- Influenza vaccines have a short but illustrious history -- The epidemiology of influenza and its control -- Influenza and influenza vaccination in children -- The immune response to influenza A viruses -- Correlates of protection against influenza -- The role of animal models in influenza vaccine research -- Live attenuated influenza vaccine -- MF59: A safe and potent oil in water emulsion adjuvant for influenza vaccines, which induces enhanced protection against virus challenge -- Non-recent history of influenza pandemics, vaccines, and adjuvants -- Waiting for a pandemic -- Modeling influenza pandemic and interventions. |
Record Nr. | UNINA-9910451475703321 |
Basel ; ; Boston, : Birkhäuser, c2008 | ||
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Lo trovi qui: Univ. Federico II | ||
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Influenza vaccines for the future [[electronic resource] /] / Rino Rappuoli, Giuseppe Del Giudice, editors |
Edizione | [1st ed. 2008.] |
Pubbl/distr/stampa | Basel ; ; Boston, : Birkhäuser, c2008 |
Descrizione fisica | 1 online resource (306 p.) |
Disciplina | 614.5/18 |
Altri autori (Persone) |
RappuoliRino
Del GiudiceGiuseppe |
Collana | Birkhäuser advances in infectious diseases |
Soggetto topico |
Influenza vaccines
Influenza Influenza viruses |
ISBN | 3-7643-8371-2 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Influenza virus: The biology of a changing virus -- Influenza vaccines have a short but illustrious history -- The epidemiology of influenza and its control -- Influenza and influenza vaccination in children -- The immune response to influenza A viruses -- Correlates of protection against influenza -- The role of animal models in influenza vaccine research -- Live attenuated influenza vaccine -- MF59: A safe and potent oil in water emulsion adjuvant for influenza vaccines, which induces enhanced protection against virus challenge -- Non-recent history of influenza pandemics, vaccines, and adjuvants -- Waiting for a pandemic -- Modeling influenza pandemic and interventions. |
Record Nr. | UNINA-9910782093103321 |
Basel ; ; Boston, : Birkhäuser, c2008 | ||
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Lo trovi qui: Univ. Federico II | ||
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Influenza vaccines for the future [[electronic resource] /] / Rino Rappuoli, Giuseppe Del Giudice, editors |
Edizione | [1st ed. 2008.] |
Pubbl/distr/stampa | Basel ; ; Boston, : Birkhäuser, c2008 |
Descrizione fisica | 1 online resource (306 p.) |
Disciplina | 614.5/18 |
Altri autori (Persone) |
RappuoliRino
Del GiudiceGiuseppe |
Collana | Birkhäuser advances in infectious diseases |
Soggetto topico |
Influenza vaccines
Influenza Influenza viruses |
ISBN | 3-7643-8371-2 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Influenza virus: The biology of a changing virus -- Influenza vaccines have a short but illustrious history -- The epidemiology of influenza and its control -- Influenza and influenza vaccination in children -- The immune response to influenza A viruses -- Correlates of protection against influenza -- The role of animal models in influenza vaccine research -- Live attenuated influenza vaccine -- MF59: A safe and potent oil in water emulsion adjuvant for influenza vaccines, which induces enhanced protection against virus challenge -- Non-recent history of influenza pandemics, vaccines, and adjuvants -- Waiting for a pandemic -- Modeling influenza pandemic and interventions. |
Record Nr. | UNINA-9910825152603321 |
Basel ; ; Boston, : Birkhäuser, c2008 | ||
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Lo trovi qui: Univ. Federico II | ||
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Protein and Sugar Export and Assembly in Gram-positive Bacteria [[electronic resource] /] / edited by Fabio Bagnoli, Rino Rappuoli |
Edizione | [1st ed. 2017.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
Descrizione fisica | 1 online resource (X, 337 p.) |
Disciplina | 614.579 |
Collana | Current Topics in Microbiology and Immunology |
Soggetto topico |
Medical microbiology
Medical biochemistry Molecular biology Medical Microbiology Medical Biochemistry Molecular Medicine |
ISBN | 3-319-56014-X |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Envelope structures of Gram-positive bacteria -- Translocation of proteins across the plasma membrane and cell envelope -- Type I signal peptidases -- The Sec system -- The twin-arginine protein translocation (Tat) system -- ExPortal: a microdomain for protein secretion in Gram-positive bacteria -- Spatial positioning of cell wall-anchored proteins -- Anchoring of LPXTG-like proteins to the cell wall envelope -- Export and processing of lipoproteins -- Pilus assembly in Gram-positive bacteria -- S-layers and related proteins: their structure, mechanisms of secretion and anchoring and their diverse functions -- Membrane translocation and assembly of sugar polymer precursors -- Type VII secretion systems -- Predicting subcellular localization of proteins by bioinformatics algorithms -- The secretome of Gram-positive bacteria -- Post-translocational folding of secretory proteins -- Protein secretion biotechnology in Gram-positive bacteria -- Exploiting Gram positive sortases for protein engineering. |
Record Nr. | UNINA-9910253932103321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
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Lo trovi qui: Univ. Federico II | ||
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Staphylococcus aureus [[electronic resource] ] : Microbiology, Pathology, Immunology, Therapy and Prophylaxis / / edited by Fabio Bagnoli, Rino Rappuoli, Guido Grandi |
Edizione | [1st ed. 2017.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
Descrizione fisica | 1 online resource (XII, 540 p.) |
Disciplina | 616.01 |
Collana | Current Topics in Microbiology and Immunology |
Soggetto topico |
Immunology
Infectious diseases Vaccines Infectious Diseases Vaccine |
ISBN | 3-319-72063-5 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Clinical microbiology, transmission and carriage of Staphylococcus aureus -- Worldwide Epidemiology and antibiotic resistance of Staphylococcus aureus -- Structure and function of surface polysaccharides of Staphylococcus aureus -- Structure and function of surface proteins of Staphylococcus aureus -- Staphylococcus aureus pore-forming toxins.-Regulation of Staphylococcus aureus genes -- Staphylococcus aureus-associated Skin and Soft Tissue Infections.- Staphylococcus aureus-associated Musculoskeletal Infections -- Bacteremia, Sepsis, and Infective Endocarditis associated to Staphylococcus aureus -- Staphylococcus aureus as a zoonotic pathogen -- Antibiotic therapy of Staphylococcus aureus -- Innate immune responses against Staphylococcus aureus -- Adaptive immune responses against Staphylococcus aureus -- Immunevasion mechanisms of Staphylococcus aureus -- Vaccines and target populations for Staphylococcus aureus -- Bacteriophage and lysine therapy of Staphylococcus aureus. |
Record Nr. | UNINA-9910255451503321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
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Lo trovi qui: Univ. Federico II | ||
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