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Advanced vaccine research : methods for the decade of vaccines / / edited by Fabio Bagnoli and Rino Rappuoli
Advanced vaccine research : methods for the decade of vaccines / / edited by Fabio Bagnoli and Rino Rappuoli
Pubbl/distr/stampa Norfolk, England : , : Caister Academic Press, , [2015]
Descrizione fisica 1 online resource (474 p.)
Disciplina 615.372
Soggetto topico Vaccines - Research
Drug development
Soggetto genere / forma Electronic books.
ISBN 1-910190-04-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Contributors; Current Books of Interest; Preface; Part I: Innovative Technologies and Approaches in Vaccine Research; 1: Deep Sequencing in Vaccine Research, Development and Surveillance ; Impact of DNA sequencing on vaccines research and development; Deep sequencing potential to transform vaccinology; 2: New Bioinformatics Algorithms Applied to Deep Sequencing Projects ; Introduction; Better understating of host and pathogen genomes; Computational approaches to study adaptive immune responses; Better understanding of transcriptome
Epigenomics: understanding of inheritable chemical changesMetagenomics: finding new pathogens and strains; Bioinformatics challenges; 3: Comparative Genomics Approaches for Tracking the Emergence and Spread of Disease-associated Bacteria; Background; Comparative genomics of disease-associated bacteria; Assays for identification of disease-associated bacteria based on insights from comparative genomics; Conclusions; 4: Quantitative Proteomics in Vaccine Research; Introduction; Quantitative proteomics based on gel electrophoresis; Quantitative proteomics based on differential mass tag
Label-free technologies and targeted proteomicsMass spectrometry for viral vaccinology; Proteomic technology for vaccine development ; Combining proteomics and system biology to improve vaccines; Concluding remarks; 5: Structural Biology in Vaccine Research; Introduction; Experimental mapping and computational prediction of epitopes; Examples of structural vaccinology for bacterial and viral pathogens; Concluding remarks and future directions; 6: Cellular Screens to Interrogate the Human T- and B-cell Repertoires and Design Better Vaccines ; Introduction
Generation of naive B- and T-cell repertoires7: Novel Strategies of Vaccine Administration: The Science Behind Epidermal and Dermal Immunization; Introduction; The skin layers; Skin antigen-presenting cells and other players in vaccination; Principles and methods in skin immunization; Vaccine formulation and immunity; Immunological advantage of epidermal and dermal immunization; 8: Toll-like Receptors as Targets to Develop Novel Adjuvants; Introduction; Innate immunity; TLR-based adjuvants in high-priority vaccines; Lessons learned from studies of TLR agonists as adjuvants
Safety considerations of TLR agonistsChallenges for the next decade; 9: The Importance of Cell-mediated Immunity for Bacterial Vaccines ; Introduction; T-cell responses to bacterial infection; Targeting cellular immunity for novel anti-bacterial vaccine design; 10: T-cell-inducing Vaccines; Introduction; How can we measure T-cell responses?; Technologies for inducing T-cell responses by vaccination; Heterologous prime-boost immunization; Successful clinical development of T-cell vaccines; 11: Exploiting the Mutanome for Personalized Cancer Immunotherapy
Cancer mutations as therapeutic targets
Record Nr. UNINA-9910460918103321
Norfolk, England : , : Caister Academic Press, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Advanced vaccine research : methods for the decade of vaccines / / edited by Fabio Bagnoli and Rino Rappuoli
Advanced vaccine research : methods for the decade of vaccines / / edited by Fabio Bagnoli and Rino Rappuoli
Pubbl/distr/stampa Norfolk, England : , : Caister Academic Press, , [2015]
Descrizione fisica 1 online resource (474 p.)
Disciplina 615.372
Soggetto topico Vaccines - Research
Drug development
ISBN 1-910190-04-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Contributors; Current Books of Interest; Preface; Part I: Innovative Technologies and Approaches in Vaccine Research; 1: Deep Sequencing in Vaccine Research, Development and Surveillance ; Impact of DNA sequencing on vaccines research and development; Deep sequencing potential to transform vaccinology; 2: New Bioinformatics Algorithms Applied to Deep Sequencing Projects ; Introduction; Better understating of host and pathogen genomes; Computational approaches to study adaptive immune responses; Better understanding of transcriptome
Epigenomics: understanding of inheritable chemical changesMetagenomics: finding new pathogens and strains; Bioinformatics challenges; 3: Comparative Genomics Approaches for Tracking the Emergence and Spread of Disease-associated Bacteria; Background; Comparative genomics of disease-associated bacteria; Assays for identification of disease-associated bacteria based on insights from comparative genomics; Conclusions; 4: Quantitative Proteomics in Vaccine Research; Introduction; Quantitative proteomics based on gel electrophoresis; Quantitative proteomics based on differential mass tag
Label-free technologies and targeted proteomicsMass spectrometry for viral vaccinology; Proteomic technology for vaccine development ; Combining proteomics and system biology to improve vaccines; Concluding remarks; 5: Structural Biology in Vaccine Research; Introduction; Experimental mapping and computational prediction of epitopes; Examples of structural vaccinology for bacterial and viral pathogens; Concluding remarks and future directions; 6: Cellular Screens to Interrogate the Human T- and B-cell Repertoires and Design Better Vaccines ; Introduction
Generation of naive B- and T-cell repertoires7: Novel Strategies of Vaccine Administration: The Science Behind Epidermal and Dermal Immunization; Introduction; The skin layers; Skin antigen-presenting cells and other players in vaccination; Principles and methods in skin immunization; Vaccine formulation and immunity; Immunological advantage of epidermal and dermal immunization; 8: Toll-like Receptors as Targets to Develop Novel Adjuvants; Introduction; Innate immunity; TLR-based adjuvants in high-priority vaccines; Lessons learned from studies of TLR agonists as adjuvants
Safety considerations of TLR agonistsChallenges for the next decade; 9: The Importance of Cell-mediated Immunity for Bacterial Vaccines ; Introduction; T-cell responses to bacterial infection; Targeting cellular immunity for novel anti-bacterial vaccine design; 10: T-cell-inducing Vaccines; Introduction; How can we measure T-cell responses?; Technologies for inducing T-cell responses by vaccination; Heterologous prime-boost immunization; Successful clinical development of T-cell vaccines; 11: Exploiting the Mutanome for Personalized Cancer Immunotherapy
Cancer mutations as therapeutic targets
Record Nr. UNINA-9910787429503321
Norfolk, England : , : Caister Academic Press, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Advanced vaccine research : methods for the decade of vaccines / / edited by Fabio Bagnoli and Rino Rappuoli
Advanced vaccine research : methods for the decade of vaccines / / edited by Fabio Bagnoli and Rino Rappuoli
Pubbl/distr/stampa Norfolk, England : , : Caister Academic Press, , [2015]
Descrizione fisica 1 online resource (474 p.)
Disciplina 615.372
Soggetto topico Vaccines - Research
Drug development
ISBN 1-910190-04-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Contributors; Current Books of Interest; Preface; Part I: Innovative Technologies and Approaches in Vaccine Research; 1: Deep Sequencing in Vaccine Research, Development and Surveillance ; Impact of DNA sequencing on vaccines research and development; Deep sequencing potential to transform vaccinology; 2: New Bioinformatics Algorithms Applied to Deep Sequencing Projects ; Introduction; Better understating of host and pathogen genomes; Computational approaches to study adaptive immune responses; Better understanding of transcriptome
Epigenomics: understanding of inheritable chemical changesMetagenomics: finding new pathogens and strains; Bioinformatics challenges; 3: Comparative Genomics Approaches for Tracking the Emergence and Spread of Disease-associated Bacteria; Background; Comparative genomics of disease-associated bacteria; Assays for identification of disease-associated bacteria based on insights from comparative genomics; Conclusions; 4: Quantitative Proteomics in Vaccine Research; Introduction; Quantitative proteomics based on gel electrophoresis; Quantitative proteomics based on differential mass tag
Label-free technologies and targeted proteomicsMass spectrometry for viral vaccinology; Proteomic technology for vaccine development ; Combining proteomics and system biology to improve vaccines; Concluding remarks; 5: Structural Biology in Vaccine Research; Introduction; Experimental mapping and computational prediction of epitopes; Examples of structural vaccinology for bacterial and viral pathogens; Concluding remarks and future directions; 6: Cellular Screens to Interrogate the Human T- and B-cell Repertoires and Design Better Vaccines ; Introduction
Generation of naive B- and T-cell repertoires7: Novel Strategies of Vaccine Administration: The Science Behind Epidermal and Dermal Immunization; Introduction; The skin layers; Skin antigen-presenting cells and other players in vaccination; Principles and methods in skin immunization; Vaccine formulation and immunity; Immunological advantage of epidermal and dermal immunization; 8: Toll-like Receptors as Targets to Develop Novel Adjuvants; Introduction; Innate immunity; TLR-based adjuvants in high-priority vaccines; Lessons learned from studies of TLR agonists as adjuvants
Safety considerations of TLR agonistsChallenges for the next decade; 9: The Importance of Cell-mediated Immunity for Bacterial Vaccines ; Introduction; T-cell responses to bacterial infection; Targeting cellular immunity for novel anti-bacterial vaccine design; 10: T-cell-inducing Vaccines; Introduction; How can we measure T-cell responses?; Technologies for inducing T-cell responses by vaccination; Heterologous prime-boost immunization; Successful clinical development of T-cell vaccines; 11: Exploiting the Mutanome for Personalized Cancer Immunotherapy
Cancer mutations as therapeutic targets
Record Nr. UNINA-9910820979003321
Norfolk, England : , : Caister Academic Press, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Antibodies for infectious diseases / / edited by James E. Crowe, Jr., Diana Boraschi and Rino Rappuoli
Antibodies for infectious diseases / / edited by James E. Crowe, Jr., Diana Boraschi and Rino Rappuoli
Pubbl/distr/stampa Washington, District of Columbia : , : ASM Press, , 2015
Descrizione fisica 1 online resource (476 p.)
Disciplina 616.0798
Soggetto topico Immunoglobulins
Communicable diseases - Immunological aspects
ISBN 1-68367-340-9
1-68367-098-1
1-55581-741-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ""Cover ""; ""Half Title ""; ""Title Page ""; ""Copyright ""; ""Contents ""; ""Contr ibutors ""; ""Preface ""; ""INTRODUCTION""; ""Chapter 1: History and Practice: Antibodies in Infectious Diseases""; ""HISTORICAL PERSPECTIVE""; ""INTRODUCTION TO ANTIBODIES""; ""METHODS AND PLATFORMS FOR GENERATING ANTIBODIES""; ""STRATEGIC CONSIDERATIONS IN DEVELOPING ANTIBODY-BASED THERAPIES FOR INFECTIOUS DISEASES""; ""EXAMPLES OF ANTIBODIES THAT ARE OR WERE IN DEVELOPMENT FOR INFECTIOUS DISEASES""; ""FUTURE PERSPECTIVES FOR ANTIBODY TREATMENTS IN INFECTIOUS DISEASES""; ""ACKNOWLEDGMENT""; ""CITATION""
""REFERENCES""""GENERAL FEATURES OF IMMUNOGLOBULINS""; ""Chapter 2: Functions of Antibodies""; ""INTRODUCTION""; ""ANTIBODY FUNCTIONS INDEPENDENT OF EFFECTOR CELLS OR EFFECTOR MOLECULES""; ""INHIBITION OF LATER STEPS""; ""ANTIBODY FUNCTIONS DEPENDENT ON COMPLEMENT""; ""ANTIBODY FUNCTIONS DEPENDENT ON Fc-Fc RECEPTOR INTERACTIONS""; ""OTHER ANTIBODY FUNCTIONS""; ""CONCLUSIONS""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES""; ""Chapter 3: Antibody Structure""; ""BASICS OF ANTIBODY STRUCTURE""; ""CDR H3: SIZE AND SUBTERFUGE""; ""HEAVY CHAIN DOMINATION AND FRAMEWORK CONTACTS""
""DISULFIDES IN THE CDRs""""SELF-CARBOHYDRATE RECOGNITION: PENETRATING THE GLYCAN SHIELD""; ""UNUSUAL INDELS""; ""MECHANISMS OF ANTIBODY NEUTRALIZATION""; ""SUMMARY""; ""ACKNOWLEDGMENT""; ""CITATION""; ""REFERENCES""; ""Chapter 4: The Role of Complement in Antibody Therapy for Infectious Diseases""; ""INTRODUCTION""; ""COMPLEMENT ACTIVATION""; ""Ab-MEDIATED COMPLEMENT ACTIVATION""; ""EFFECTOR RESPONSES AND THEIR ROLE IN MAb TREATMENTS""; ""MANIPULATING Ab-MEDIATED COMPLEMENT RESPONSES""; ""COMPLEMENT EVASIVE PROPERTIES OF PATHOGENS""; ""CONCLUSIONS AND FUTURE PERSPECTIVE""
""ACKNOWLEDGMENTS""""CITATION""; ""REFERENCES""; ""Chapter 5: Immunoglobulin E and Allergy: Antibodies in Immune Inflammation and Treatment""; ""IMMUNOLOGICAL MECHANISMS OF ALLERGIC DISEASES AND THE ROLE OF IgE ANTIBODIES""; ""IgE ANTIBODIES IN INFECTIOUS DISEASES""; ""ANTIBODIES IN THE TREATMENT OF ALLERGIES""; ""THE OPPOSITE SIDE OF THE COIN: HARNESSING THE ALLERGIC RESPONSE AGAINST CANCER AND THE EMERGENCE OF ANTIBODIES OF THE IgE CLASS FOR CANCER THERAPY""; ""CONCLUDING REMARKS AND FUTURE ROLES OF ANTIBODIES IN THERAPY""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES""
""ANTIBODY DISCOVERY APPROACHES""""Chapter 6: Phage and Yeast Display""; ""DISCOVERY OF THERAPEUTIC ANTIBODIES USING PHAGE DISPLAY TECHNOLOGY""; ""DISCOVERY OF THERAPEUTIC ANTIBODIES USING YEAST DISPLAY TECHNOLOGY""; ""CONCLUSIONS""; ""ACKNOWLEDGMENT""; ""CITATION""; ""REFERENCES""; ""Chapter 7: Efficient Methods To Isolate Human Monoclonal Antibodies from Memory B Cells and Plasma Cells""; ""MANY WAYS TO MAKE HUMAN MONOCLONAL ANTIBODIES""; ""EFFICIENT IMMORTALIZATION OF MEMORY B CELLS BY USING EBV AND CpG""
""LONG-TERM CULTURE OF SINGLE PLASMA CELLS AND THEIR INTERROGATION USING MULTIPLE ASSAYS""
Record Nr. UNINA-9910555131903321
Washington, District of Columbia : , : ASM Press, , 2015
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Antibodies for infectious diseases / / edited by James E. Crowe, Jr., Diana Boraschi and Rino Rappuoli
Antibodies for infectious diseases / / edited by James E. Crowe, Jr., Diana Boraschi and Rino Rappuoli
Pubbl/distr/stampa Washington, District of Columbia : , : ASM Press, , 2015
Descrizione fisica 1 online resource (476 p.)
Disciplina 616.0798
Soggetto topico Immunoglobulins
Communicable diseases - Immunological aspects
ISBN 1-68367-340-9
1-68367-098-1
1-55581-741-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ""Cover ""; ""Half Title ""; ""Title Page ""; ""Copyright ""; ""Contents ""; ""Contr ibutors ""; ""Preface ""; ""INTRODUCTION""; ""Chapter 1: History and Practice: Antibodies in Infectious Diseases""; ""HISTORICAL PERSPECTIVE""; ""INTRODUCTION TO ANTIBODIES""; ""METHODS AND PLATFORMS FOR GENERATING ANTIBODIES""; ""STRATEGIC CONSIDERATIONS IN DEVELOPING ANTIBODY-BASED THERAPIES FOR INFECTIOUS DISEASES""; ""EXAMPLES OF ANTIBODIES THAT ARE OR WERE IN DEVELOPMENT FOR INFECTIOUS DISEASES""; ""FUTURE PERSPECTIVES FOR ANTIBODY TREATMENTS IN INFECTIOUS DISEASES""; ""ACKNOWLEDGMENT""; ""CITATION""
""REFERENCES""""GENERAL FEATURES OF IMMUNOGLOBULINS""; ""Chapter 2: Functions of Antibodies""; ""INTRODUCTION""; ""ANTIBODY FUNCTIONS INDEPENDENT OF EFFECTOR CELLS OR EFFECTOR MOLECULES""; ""INHIBITION OF LATER STEPS""; ""ANTIBODY FUNCTIONS DEPENDENT ON COMPLEMENT""; ""ANTIBODY FUNCTIONS DEPENDENT ON Fc-Fc RECEPTOR INTERACTIONS""; ""OTHER ANTIBODY FUNCTIONS""; ""CONCLUSIONS""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES""; ""Chapter 3: Antibody Structure""; ""BASICS OF ANTIBODY STRUCTURE""; ""CDR H3: SIZE AND SUBTERFUGE""; ""HEAVY CHAIN DOMINATION AND FRAMEWORK CONTACTS""
""DISULFIDES IN THE CDRs""""SELF-CARBOHYDRATE RECOGNITION: PENETRATING THE GLYCAN SHIELD""; ""UNUSUAL INDELS""; ""MECHANISMS OF ANTIBODY NEUTRALIZATION""; ""SUMMARY""; ""ACKNOWLEDGMENT""; ""CITATION""; ""REFERENCES""; ""Chapter 4: The Role of Complement in Antibody Therapy for Infectious Diseases""; ""INTRODUCTION""; ""COMPLEMENT ACTIVATION""; ""Ab-MEDIATED COMPLEMENT ACTIVATION""; ""EFFECTOR RESPONSES AND THEIR ROLE IN MAb TREATMENTS""; ""MANIPULATING Ab-MEDIATED COMPLEMENT RESPONSES""; ""COMPLEMENT EVASIVE PROPERTIES OF PATHOGENS""; ""CONCLUSIONS AND FUTURE PERSPECTIVE""
""ACKNOWLEDGMENTS""""CITATION""; ""REFERENCES""; ""Chapter 5: Immunoglobulin E and Allergy: Antibodies in Immune Inflammation and Treatment""; ""IMMUNOLOGICAL MECHANISMS OF ALLERGIC DISEASES AND THE ROLE OF IgE ANTIBODIES""; ""IgE ANTIBODIES IN INFECTIOUS DISEASES""; ""ANTIBODIES IN THE TREATMENT OF ALLERGIES""; ""THE OPPOSITE SIDE OF THE COIN: HARNESSING THE ALLERGIC RESPONSE AGAINST CANCER AND THE EMERGENCE OF ANTIBODIES OF THE IgE CLASS FOR CANCER THERAPY""; ""CONCLUDING REMARKS AND FUTURE ROLES OF ANTIBODIES IN THERAPY""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES""
""ANTIBODY DISCOVERY APPROACHES""""Chapter 6: Phage and Yeast Display""; ""DISCOVERY OF THERAPEUTIC ANTIBODIES USING PHAGE DISPLAY TECHNOLOGY""; ""DISCOVERY OF THERAPEUTIC ANTIBODIES USING YEAST DISPLAY TECHNOLOGY""; ""CONCLUSIONS""; ""ACKNOWLEDGMENT""; ""CITATION""; ""REFERENCES""; ""Chapter 7: Efficient Methods To Isolate Human Monoclonal Antibodies from Memory B Cells and Plasma Cells""; ""MANY WAYS TO MAKE HUMAN MONOCLONAL ANTIBODIES""; ""EFFICIENT IMMORTALIZATION OF MEMORY B CELLS BY USING EBV AND CpG""
""LONG-TERM CULTURE OF SINGLE PLASMA CELLS AND THEIR INTERROGATION USING MULTIPLE ASSAYS""
Record Nr. UNINA-9910830911403321
Washington, District of Columbia : , : ASM Press, , 2015
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Influenza vaccines for the future [[electronic resource] /] / Rino Rappuoli, Giuseppe Del Giudice, editors
Influenza vaccines for the future [[electronic resource] /] / Rino Rappuoli, Giuseppe Del Giudice, editors
Edizione [1st ed. 2008.]
Pubbl/distr/stampa Basel ; ; Boston, : Birkhäuser, c2008
Descrizione fisica 1 online resource (306 p.)
Disciplina 614.5/18
Altri autori (Persone) RappuoliRino
Del GiudiceGiuseppe
Collana Birkhäuser advances in infectious diseases
Soggetto topico Influenza vaccines
Influenza
Influenza viruses
Soggetto genere / forma Electronic books.
ISBN 3-7643-8371-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Influenza virus: The biology of a changing virus -- Influenza vaccines have a short but illustrious history -- The epidemiology of influenza and its control -- Influenza and influenza vaccination in children -- The immune response to influenza A viruses -- Correlates of protection against influenza -- The role of animal models in influenza vaccine research -- Live attenuated influenza vaccine -- MF59: A safe and potent oil in water emulsion adjuvant for influenza vaccines, which induces enhanced protection against virus challenge -- Non-recent history of influenza pandemics, vaccines, and adjuvants -- Waiting for a pandemic -- Modeling influenza pandemic and interventions.
Record Nr. UNINA-9910451475703321
Basel ; ; Boston, : Birkhäuser, c2008
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Influenza vaccines for the future [[electronic resource] /] / Rino Rappuoli, Giuseppe Del Giudice, editors
Influenza vaccines for the future [[electronic resource] /] / Rino Rappuoli, Giuseppe Del Giudice, editors
Edizione [1st ed. 2008.]
Pubbl/distr/stampa Basel ; ; Boston, : Birkhäuser, c2008
Descrizione fisica 1 online resource (306 p.)
Disciplina 614.5/18
Altri autori (Persone) RappuoliRino
Del GiudiceGiuseppe
Collana Birkhäuser advances in infectious diseases
Soggetto topico Influenza vaccines
Influenza
Influenza viruses
ISBN 3-7643-8371-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Influenza virus: The biology of a changing virus -- Influenza vaccines have a short but illustrious history -- The epidemiology of influenza and its control -- Influenza and influenza vaccination in children -- The immune response to influenza A viruses -- Correlates of protection against influenza -- The role of animal models in influenza vaccine research -- Live attenuated influenza vaccine -- MF59: A safe and potent oil in water emulsion adjuvant for influenza vaccines, which induces enhanced protection against virus challenge -- Non-recent history of influenza pandemics, vaccines, and adjuvants -- Waiting for a pandemic -- Modeling influenza pandemic and interventions.
Record Nr. UNINA-9910782093103321
Basel ; ; Boston, : Birkhäuser, c2008
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Influenza vaccines for the future [[electronic resource] /] / Rino Rappuoli, Giuseppe Del Giudice, editors
Influenza vaccines for the future [[electronic resource] /] / Rino Rappuoli, Giuseppe Del Giudice, editors
Edizione [1st ed. 2008.]
Pubbl/distr/stampa Basel ; ; Boston, : Birkhäuser, c2008
Descrizione fisica 1 online resource (306 p.)
Disciplina 614.5/18
Altri autori (Persone) RappuoliRino
Del GiudiceGiuseppe
Collana Birkhäuser advances in infectious diseases
Soggetto topico Influenza vaccines
Influenza
Influenza viruses
ISBN 3-7643-8371-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Influenza virus: The biology of a changing virus -- Influenza vaccines have a short but illustrious history -- The epidemiology of influenza and its control -- Influenza and influenza vaccination in children -- The immune response to influenza A viruses -- Correlates of protection against influenza -- The role of animal models in influenza vaccine research -- Live attenuated influenza vaccine -- MF59: A safe and potent oil in water emulsion adjuvant for influenza vaccines, which induces enhanced protection against virus challenge -- Non-recent history of influenza pandemics, vaccines, and adjuvants -- Waiting for a pandemic -- Modeling influenza pandemic and interventions.
Record Nr. UNINA-9910825152603321
Basel ; ; Boston, : Birkhäuser, c2008
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Protein and Sugar Export and Assembly in Gram-positive Bacteria [[electronic resource] /] / edited by Fabio Bagnoli, Rino Rappuoli
Protein and Sugar Export and Assembly in Gram-positive Bacteria [[electronic resource] /] / edited by Fabio Bagnoli, Rino Rappuoli
Edizione [1st ed. 2017.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
Descrizione fisica 1 online resource (X, 337 p.)
Disciplina 614.579
Collana Current Topics in Microbiology and Immunology
Soggetto topico Medical microbiology
Medical biochemistry
Molecular biology
Medical Microbiology
Medical Biochemistry
Molecular Medicine
ISBN 3-319-56014-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Envelope structures of Gram-positive bacteria -- Translocation of proteins across the plasma membrane and cell envelope -- Type I signal peptidases -- The Sec system -- The twin-arginine protein translocation (Tat) system -- ExPortal: a microdomain for protein secretion in Gram-positive bacteria -- Spatial positioning of cell wall-anchored proteins -- Anchoring of LPXTG-like proteins to the cell wall envelope -- Export and processing of lipoproteins -- Pilus assembly in Gram-positive bacteria -- S-layers and related proteins: their structure, mechanisms of secretion and anchoring and their diverse functions -- Membrane translocation and assembly of sugar polymer precursors -- Type VII secretion systems -- Predicting subcellular localization of proteins by bioinformatics algorithms -- The secretome of Gram-positive bacteria -- Post-translocational folding of secretory proteins -- Protein secretion biotechnology in Gram-positive bacteria -- Exploiting Gram positive sortases for protein engineering.
Record Nr. UNINA-9910253932103321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Staphylococcus aureus [[electronic resource] ] : Microbiology, Pathology, Immunology, Therapy and Prophylaxis / / edited by Fabio Bagnoli, Rino Rappuoli, Guido Grandi
Staphylococcus aureus [[electronic resource] ] : Microbiology, Pathology, Immunology, Therapy and Prophylaxis / / edited by Fabio Bagnoli, Rino Rappuoli, Guido Grandi
Edizione [1st ed. 2017.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
Descrizione fisica 1 online resource (XII, 540 p.)
Disciplina 616.01
Collana Current Topics in Microbiology and Immunology
Soggetto topico Immunology
Infectious diseases
Vaccines
Infectious Diseases
Vaccine
ISBN 3-319-72063-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Clinical microbiology, transmission and carriage of Staphylococcus aureus -- Worldwide Epidemiology and antibiotic resistance of Staphylococcus aureus -- Structure and function of surface polysaccharides of Staphylococcus aureus -- Structure and function of surface proteins of Staphylococcus aureus -- Staphylococcus aureus pore-forming toxins.-Regulation of Staphylococcus aureus genes -- Staphylococcus aureus-associated Skin and Soft Tissue Infections.- Staphylococcus aureus-associated Musculoskeletal Infections -- Bacteremia, Sepsis, and Infective Endocarditis associated to Staphylococcus aureus -- Staphylococcus aureus as a zoonotic pathogen -- Antibiotic therapy of Staphylococcus aureus -- Innate immune responses against Staphylococcus aureus -- Adaptive immune responses against Staphylococcus aureus -- Immunevasion mechanisms of Staphylococcus aureus -- Vaccines and target populations for Staphylococcus aureus -- Bacteriophage and lysine therapy of Staphylococcus aureus.
Record Nr. UNINA-9910255451503321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui