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Drug Resistance in Leishmania Parasites : Consequences, Molecular Mechanisms and Possible Treatments / / edited by Alicia Ponte-Sucre, Maritza Padrón-Nieves
| Drug Resistance in Leishmania Parasites : Consequences, Molecular Mechanisms and Possible Treatments / / edited by Alicia Ponte-Sucre, Maritza Padrón-Nieves |
| Edizione | [2nd ed. 2018.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
| Descrizione fisica | 1 online resource (380 pages) |
| Disciplina | 616.9364 |
| Soggetto topico |
Drug resistance
Infectious diseases Pharmaceutical technology Vaccines Parasitology Microbiology Drug Resistance Infectious Diseases Pharmaceutical Sciences/Technology Vaccine |
| ISBN | 3-319-74186-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Prologue -- Introduction -- Part I Determinant features in Leishmaniasis -- Molecular evolution and phylogeny of Leishmania -- The role of reservoirs: canine Leishmaniasis -- Epidemiology of Leishmaniasis in the time of drug resistance -- The role of the immune system in resistance to infection -- Part II Challenges in the diagnosis, treatment and control of Leishmaniasis in the times of drug resistance -- Co-infection with HIV -- Visceral Leishmaniasis -- Tegumentary Leishmaniasis -- Antimony accounted sequel post Kala-Azar dermal Leishmaniasis -- Part III Molecular featrues of drug resistant Leishmania -- Genetic Expression and drug resistance, the role of proteomics -- The role of AMC transporters in drug-resistant Leishmania -- Functional analysis of Leishmania membrane (non AMC) transporters involved in drug resistance -- Part IV Pharmacology and chemotherapy of Leishmaniasis -- Classical vs. novel treatment regimens -- Bioinformatics in Leishmania drug design -- Leishmanis mitochondria, a druggable organelle -- P-glycoprotein-like transporters in Leishmania: a search for reversal agents -- Part V Strategies to circumvent drug resistance in Leishmania -- The relevance of susceptibility tests, breakpoints and markers -- The concept of fitness in Leishmania. |
| Record Nr. | UNINA-9910298399603321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Drug resistance in leishmania parasites : consequences, molecular mechanisms and possible treatments / / Alicia Ponte-Sucre, Emilia Diaz, Maritza Padron-Nieves, editors
| Drug resistance in leishmania parasites : consequences, molecular mechanisms and possible treatments / / Alicia Ponte-Sucre, Emilia Diaz, Maritza Padron-Nieves, editors |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | New York, : Springer, 2013 |
| Descrizione fisica | 1 online resource (457 p.) |
| Disciplina |
616.9
616.9/364 |
| Altri autori (Persone) |
DiazEmilia
Padron-NievesMaritza Ponte-SucreAlicia |
| Soggetto topico |
Leishmania
Parasites |
| ISBN |
1-283-61268-2
9786613925138 3-7091-1125-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | pt. 1. Determinant features in leishmaniasis -- pt. 2. Leishmania and the immune system -- pt. 3. Challenges in the diagnosis, treatment and control of leishmaniasis in times of drug resistance -- pt. 4. Molecular features of drug-resistant leishmania -- pt. 5. Pharmacology and chemotherapy of leishmaniasis -- pt. 6. Strategies to circumvent drug resistance in leishmania. |
| Record Nr. | UNINA-9910438022303321 |
| New York, : Springer, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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