Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing
| Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing |
| Autore | Pörtner Ralf |
| Descrizione fisica | 1 online resource (226 p.) |
| Soggetto topico |
History of engineering and technology
Technology: general issues |
| Soggetto non controllato |
Adeno-associated virus
Bayes optimization biopharmaceutical manufacturing bioprocess bioreactor bioreactor characterization biosensor biotherapeutics production cell culture cell culture model Chinese hamster ovary cells CHO DP-12 clonal cell population computational fluid dynamics continuous critical shear stress cryopreservation diabetes Escherichia coli Gaussian processes gene therapy hybrid modeling hydrodynamic gradients hydrodynamic stress inoculum train Kolmogorov length scale machine learning microcarriers model-assisted DoE monitoring monoclonal antibodies multi-objective n/a N−1 perfusion operational space Pareto optimization PAT PEI phenotypic diversity process analytical technology (PAT) process development process intensification quality by design quality by design (QbD) seed train sensors shear stress-guided production smart biomanufacturing soft-sensor spectroscopy spheroid strength surface plasmon resonance (SPR) transfection transient expression uncertainty-based upstream bioprocessing upstream processing vaccines production β-cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595072803321 |
Pörtner Ralf
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| Lo trovi qui: Univ. Federico II | ||
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Cell Culture Engineering and Technology : In appreciation to Professor Mohamed Al-Rubeai / / edited by Ralf Pörtner
| Cell Culture Engineering and Technology : In appreciation to Professor Mohamed Al-Rubeai / / edited by Ralf Pörtner |
| Autore | Pörtner Ralf |
| Edizione | [1st ed. 2021.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021 |
| Descrizione fisica | 1 online resource (552 pages) |
| Disciplina |
574.0724
571.638 |
| Collana | Cell Engineering |
| Soggetto topico |
Medicine - Research
Biology - Research Cytology Biology - Technique Regenerative medicine Biomedical engineering Biomedical Research Cell Biology Biological Techniques Regenerative Medicine and Tissue Engineering Biomedical Engineering and Bioengineering Enginyeria de teixits |
| Soggetto genere / forma | Llibres electrònics |
| ISBN |
9783030798710
9783030798703 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Biopharmaceuticals Produced from Cultivated Mammalian Cells -- Remote Control of Mammalian Therapeutic Designer Cells -- Next generation cell engineering using microRNAs -- An Omic’s data-driven approach towards engineering mammalian cell factories and bioprocesses for biopharmaceutical production -- Redesigning spent media from cell culture bioprocess to feed new bacterial fermentations -- Monoclonal antibody glycoengineering for biopharmaceutical quality assurance -- Next-generation cell engineering platform for improving recombinant protein production in mammalian cells -- Manufacturing human pluripotent stem cells and differentiated progenitors -- Biomanufacturing of Mesenchymal Stromal Cell for Therapeutic Applications -- Process Design for hMSC Products in Stirred Tank Bioreactors -- Bio-production of Adeno-associated virus for gene therapy -- Scale-up (and scale-down) of CHO cell culture, with a focus on how to adjust the various culture parameters/setpoints across different systems from lab-scale to manufacturing-scale -- Intensified and Continuous mAb Production with Single-Use Systems -- Mathematical modelling of cell culture processes -- Model-assisted design concepts for mammalian cell culture processes -- Bioprocess monitoring and control -- Industrial Monitoring of Cell Culture. |
| Record Nr. | UNINA-9910547298303321 |
Pörtner Ralf
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| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021 | ||
| Lo trovi qui: Univ. Federico II | ||
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