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Sherlock's diseases of the liver and biliary system / / edited by James S. Dooley, Anna S.F. Lok, Guadalupe Garcia-Tsao, Massimo Pinzani
| Sherlock's diseases of the liver and biliary system / / edited by James S. Dooley, Anna S.F. Lok, Guadalupe Garcia-Tsao, Massimo Pinzani |
| Edizione | [Thirteenth edition.] |
| Pubbl/distr/stampa | Hoboken, N.J. : , : Wiley Blackwell, , [2018] |
| Descrizione fisica | 1 online resource (835 pages) |
| Disciplina | 616.3/6 |
| Soggetto topico |
Liver - Diseases
Biliary tract - Diseases |
| Soggetto non controllato |
Liver
Biliary Tract Medical |
| ISBN |
1-119-23764-5
1-119-23756-4 1-119-23766-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Anatomy and Function -- Jay H Lefkowitch -- Liver Function in Health and Disease -- George Mells, Graeme Alexander -- Biopsy of the Liver -- David Patch, Tu Vinh Luong -- Coagulation in Cirrhosis -- Nicolas M Intagliata, Stephen H Caldwell -- Acute Liver Failure -- Shannan R Tujios, William M Lee -- Hepatic Fibrogenesis -- Meena B Bansal, Scott L Friedman -- Non-invasive Assessment of Fibrosis and Cirrhosis -- Avik Majumdar, Massimo Pinzani -- Hepatic Cirrhosis -- P Aiden McCormick, Rajiv Jalan -- Ascites -- Guadalupe Garcia-Tsao -- Hepatic Encephalopathy in Patients with Cirrhosis -- Marsha Y Morgan -- Portal Hypertension in Cirrhosis -- Jaime Bosch, Annalisa Berzigotti -- Vascular Disorders of the Liver and Extrahepatic Portal Hypertension -- Dominique-Charles Valla -- Jaundice and Cholestasis -- Peter L M Jansen -- Gallstones and Benign Biliary Disease -- James S Dooley, Kurinchi S Gurusamy, Brian R Davidson -- Malignant Biliary Diseases -- Rahul S Koti, John Bridgewater -- Fibropolycystic Liver Diseases and Congenital Biliary Abnormalities -- Nedim Hadžić, Mario Strazzabosco -- Primary Biliary Cholangitis -- David E J Jones -- Sclerosing Cholangitis -- Tom Hemming Karlsen, Kirsten Muri Boberg -- Autoimmune Hepatitis and Overlap Syndromes -- Ashnila Janmohamed, Gideon M Hirschfield -- Enterically Transmitted Viral Hepatitis -- Rinjal D Brahmbhatt, Anna S F Lok -- Hepatitis B -- Anna S F Lok -- Hepatitis D -- Patrizia Farci, Grazia Anna Niro -- Hepatitis C -- Geoffrey Dusheiko -- Drug-Induced Liver Injury -- Frank W DiPaola, Robert J Fontana -- Alcohol and the Liver -- Stephen Stewart, Ewan Forrest -- Iron Overload States -- Paul Adams, Heinz Zoller -- Wilson Disease -- Eve A Roberts, Karl Heinz Weiss -- Non-Alcoholic Fatty Liver Disease -- Timothy Hardy, Christopher P Day -- Nutrition and Chronic Liver Disease -- Manuela Merli -- Pregnancy and the Liver -- Rachel H Westbrook, Catherine Williamson -- The Liver in the Neonate, in Infancy, and Childhood -- Susan M Siew, Deirdre A Kelly -- The Liver in Systemic Diseases -- James S Dooley, Christopher McNamara -- The Liver in Infections -- Sanjay Bhagani, Ian Cropley -- Imaging of the Liver and Diagnostic Approach of Space-Occupying Lesions -- Neil H Davies, Dominic Yu -- Benign Liver Tumours -- Ian R Wanless -- Primary Malignant Neoplasms of the Liver -- Adam Doyle, Morris Sherman -- Hepatic Transplantation -- Lindsay Y King, Carl L Berg -- Hepatic Transplantation and HBV, HCV, and HIV Infections -- Norah A Terrault. |
| Record Nr. | UNINA-9910555014503321 |
| Hoboken, N.J. : , : Wiley Blackwell, , [2018] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Stellate cells in health and disease / / edited by Chandrashekhar R. Gandhi, Massimo Pinzani
| Stellate cells in health and disease / / edited by Chandrashekhar R. Gandhi, Massimo Pinzani |
| Pubbl/distr/stampa | Amsterdam, [Netherlands] : , : Academic Press, , 2015 |
| Descrizione fisica | 1 online resource (335 p.) |
| Disciplina | 612.35 |
| Soggetto topico | Kupffer cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Stellate Cells in Health and Disease; Copyright Page; Dedication; Contents; List of Contributors; Foreword; What have we learned?; The outlook for anti-fibrotic treatment; References; Preface; 1 History and Early Work; 1.1 Discovery of Hepatic Stellate Cells; 1.2 HSCs and Vitamin A Homeostasis; 1.3 Morphological Characteristics of HSCs; 1.4 HSCs and Liver Fibrosis; 1.5 Isolation and Culture of HSCs; 1.6 Activation and Transdifferentiation of HSCs; 1.7 Markers for HSCs; 1.8 Perspective; References; 2 Hepatic Stellate Cell Culture Models; 2.1 Isolation of Hepatic Stellate Cells
2.2 Single Cell Culture2.3 In Vitro- Versus In Vivo-Activated HSCs; 2.4 Single Cell Culture and 2D: Importance of Adhesion, Arg-Gly-Asp, and Matrix Components; 2.5 HSC Co-Cultures with Kupffer Cells, Hepatocytes, LSEC, HCC, and CC Cells; 2.6 In Vitro 3D Culture Systems; 2.7 Conclusions; References; 3 Hepatic Fibrosis: A Global Clinical Problem; 3.1 Introduction; 3.2 Chronic Viral Hepatitis; 3.2.1 Alcohol-induced liver fibrosis; 3.3 NAFLD and NASH; 3.4 Autoimmune Hepatitis, Primary Biliary Cirrhosis, and Primary Sclerosing Cholangitis; 3.5 Etiology-Driven Liver Fibrosis; 3.5.1 Perspectives References4 Stellate Cells and Hepatic Fibrosis; 4.1 Introduction; 4.2 Pathogenesis of Hepatic Fibrosis; 4.2.1 Pathological and clinical associations of hepatic fibrosis; 4.2.2 ECM composition and matrix homeostasis; 4.2.3 Cellular sources of ECM; 4.3 HSCs and Hepatic Fibrosis; 4.3.1 Initiation; 4.3.2 Perpetuation; 4.3.2.1 Retinoid loss; 4.3.2.2 Fibrogenesis; 4.3.2.3 Matrix turnover; 4.3.2.4 Chemotaxis; 4.3.2.5 Proliferation; 4.3.2.6 Contractility; 4.3.2.7 Immunoregulation; 4.3.3 Regression; 4.3.3.1 Apoptosis; 4.3.3.2 Senescence; 4.3.3.3 Reversion to an inactivated phenotype 4.4 New and Emerging Pathways of HSC Activation4.5 Conclusions; References; 5 Cytokine Production and Signaling in Stellate Cells; 5.1 Introduction; 5.2 Platelet-Derived Growth Factor; 5.3 Angiogenic Cytokines; 5.4 TGF-β Superfamily; 5.5 Chemokines; 5.6 Tumor Necrosis Factor Superfamily; 5.7 Interleukins and Interferons; 5.8 Adipokines and Other Cytokines Related to Metabolism; 5.9 Osteopontin; 5.10 Perspective; References; 6 Stellate Cells, Portal Myofibroblasts, and Epithelial-to-Mesenchymal Transition; 6.1 Introduction; 6.2 Hepatic Stellate Cells 6.2.1 Contribution of HSCs to liver fibrosis6.2.1.1 HSCs/Myofibroblasts are the primary target of anti-fibrotic therapy; 6.2.1.2 Reversibility of liver fibrosis; 6.2.1.3 Inactivation of HSCs (iHSCs); 6.2.2 Other functions of HSCs; 6.2.2.1 Distinct functions of senescent HSCs; 6.2.2.2 HSC as regulatory bystanders; 6.2.2.3 HSCs as regulators of hepatocellular damage; 6.2.2.4 The role of HSCs in liver regeneration; 6.3 Portal Fibroblasts; 6.3.1 Characterization of PFs; 6.4 Epithelial-to-Mesenchymal Transition; 6.5 Perspective; References; 7 Matrix Metalloproteinases and Their Inhibitors 7.1 Introduction |
| Record Nr. | UNINA-9910788294603321 |
| Amsterdam, [Netherlands] : , : Academic Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Stellate cells in health and disease / / edited by Chandrashekhar R. Gandhi, Massimo Pinzani
| Stellate cells in health and disease / / edited by Chandrashekhar R. Gandhi, Massimo Pinzani |
| Pubbl/distr/stampa | Amsterdam, [Netherlands] : , : Academic Press, , 2015 |
| Descrizione fisica | 1 online resource (335 p.) |
| Disciplina | 612.35 |
| Soggetto topico | Kupffer cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Stellate Cells in Health and Disease; Copyright Page; Dedication; Contents; List of Contributors; Foreword; What have we learned?; The outlook for anti-fibrotic treatment; References; Preface; 1 History and Early Work; 1.1 Discovery of Hepatic Stellate Cells; 1.2 HSCs and Vitamin A Homeostasis; 1.3 Morphological Characteristics of HSCs; 1.4 HSCs and Liver Fibrosis; 1.5 Isolation and Culture of HSCs; 1.6 Activation and Transdifferentiation of HSCs; 1.7 Markers for HSCs; 1.8 Perspective; References; 2 Hepatic Stellate Cell Culture Models; 2.1 Isolation of Hepatic Stellate Cells
2.2 Single Cell Culture2.3 In Vitro- Versus In Vivo-Activated HSCs; 2.4 Single Cell Culture and 2D: Importance of Adhesion, Arg-Gly-Asp, and Matrix Components; 2.5 HSC Co-Cultures with Kupffer Cells, Hepatocytes, LSEC, HCC, and CC Cells; 2.6 In Vitro 3D Culture Systems; 2.7 Conclusions; References; 3 Hepatic Fibrosis: A Global Clinical Problem; 3.1 Introduction; 3.2 Chronic Viral Hepatitis; 3.2.1 Alcohol-induced liver fibrosis; 3.3 NAFLD and NASH; 3.4 Autoimmune Hepatitis, Primary Biliary Cirrhosis, and Primary Sclerosing Cholangitis; 3.5 Etiology-Driven Liver Fibrosis; 3.5.1 Perspectives References4 Stellate Cells and Hepatic Fibrosis; 4.1 Introduction; 4.2 Pathogenesis of Hepatic Fibrosis; 4.2.1 Pathological and clinical associations of hepatic fibrosis; 4.2.2 ECM composition and matrix homeostasis; 4.2.3 Cellular sources of ECM; 4.3 HSCs and Hepatic Fibrosis; 4.3.1 Initiation; 4.3.2 Perpetuation; 4.3.2.1 Retinoid loss; 4.3.2.2 Fibrogenesis; 4.3.2.3 Matrix turnover; 4.3.2.4 Chemotaxis; 4.3.2.5 Proliferation; 4.3.2.6 Contractility; 4.3.2.7 Immunoregulation; 4.3.3 Regression; 4.3.3.1 Apoptosis; 4.3.3.2 Senescence; 4.3.3.3 Reversion to an inactivated phenotype 4.4 New and Emerging Pathways of HSC Activation4.5 Conclusions; References; 5 Cytokine Production and Signaling in Stellate Cells; 5.1 Introduction; 5.2 Platelet-Derived Growth Factor; 5.3 Angiogenic Cytokines; 5.4 TGF-β Superfamily; 5.5 Chemokines; 5.6 Tumor Necrosis Factor Superfamily; 5.7 Interleukins and Interferons; 5.8 Adipokines and Other Cytokines Related to Metabolism; 5.9 Osteopontin; 5.10 Perspective; References; 6 Stellate Cells, Portal Myofibroblasts, and Epithelial-to-Mesenchymal Transition; 6.1 Introduction; 6.2 Hepatic Stellate Cells 6.2.1 Contribution of HSCs to liver fibrosis6.2.1.1 HSCs/Myofibroblasts are the primary target of anti-fibrotic therapy; 6.2.1.2 Reversibility of liver fibrosis; 6.2.1.3 Inactivation of HSCs (iHSCs); 6.2.2 Other functions of HSCs; 6.2.2.1 Distinct functions of senescent HSCs; 6.2.2.2 HSC as regulatory bystanders; 6.2.2.3 HSCs as regulators of hepatocellular damage; 6.2.2.4 The role of HSCs in liver regeneration; 6.3 Portal Fibroblasts; 6.3.1 Characterization of PFs; 6.4 Epithelial-to-Mesenchymal Transition; 6.5 Perspective; References; 7 Matrix Metalloproteinases and Their Inhibitors 7.1 Introduction |
| Record Nr. | UNINA-9910814001803321 |
| Amsterdam, [Netherlands] : , : Academic Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||