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Non-small Cell Lung Cancer: Current Therapies and New Targeted Treatments
| Non-small Cell Lung Cancer: Current Therapies and New Targeted Treatments |
| Autore | Uchino Junji |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (258 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
non-small cell lung cancer
previously treated patients phase I/II trial chemotherapy docetaxel S-1 immunotherapy rechallenge retrospective analysis pulmonary pleomorphic carcinoma prognostic factor glucose transporter 1 lung cancer multiple cancers metastasis sequencing mutation genomic diagnosis FDG-PET immune checkpoint inhibitor PD-1 prognosis RAD51B methylation PD-L1 expression predictive biomarker PD-1 blockade interstitial lung disease pulmonary fibrosis radiology and other imaging non-small-cell lung cancer epidermal growth factor receptor tyrosine kinase inhibitors TP53 mutations responsiveness targeted therapy network meta-analysis stage IIIA-N2 surgery immune checkpoint inhibitors biomarker nonsmall cell lung cancer HIP1R PD-L1 RUNX1 methylation survival EGFR-TKI T790M osimertinib immune-related adverse events endocrine disorders tumor-bearing patients PD-1 inhibitors PD-L1 inhibitors meta-analysis nivolumab Expanded Access Program real-world data daily practice prognostic factors NSCLC KRAS DNA polymerase beta platinum-based first-line adjuvant chemotherapy β-catenin lung neoplasms nucleotide-diphosphate kinase recurrence unresectable salvage surgery oligometastasis |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Non-small Cell Lung Cancer |
| Record Nr. | UNINA-9910557489703321 |
Uchino Junji
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Developments in Cancer Systems Biology
| Recent Developments in Cancer Systems Biology |
| Autore | Sinha Raghu |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (272 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Sestrin2
lung cancer knockdown cancer progression bioinformatics patient survival lung adenocarcinoma circulating miR-1246 glycosaminoglycan binding prognosis PI3K-Akt signaling pathways TargetScan UBE2C cancer systems biology experimental model systems next-generation sequencing single-cell sequencing patient-derived xenografts patient-derived organoids triple-negative breast cancer personalized medicine computational methods drug repurposing clinical trials cancer stem cells ETS Elk-1 stem cell microarray brain-tumor-initiating cell (BTIC) pancreatic cancer systems biology omics biomarker genomics transcriptomics proteomics metabolomics glycomics metagenomics Ets PEA3 Ets-1 glioma optical genome mapping solid tumors cancer genomics breast ovarian cancer TCGA non-small-cell lung cancer lung adenocarcinoma (LUAD) lung squamous cell carcinoma (LUSC) differential expression SNV CNV risk group signature survival renal cancers protein interactome diagnostic biomarker prognostic biomarker virtual screening docking acute myeloid leukemia Boolean model drug resistance network |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557768503321 |
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Sinha Raghu
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of Medical Imaging in Cancers . Volume 1
| Role of Medical Imaging in Cancers . Volume 1 |
| Autore | Fanti Stefano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (312 pages) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
positron emission tomography
head and neck neoplasms neovascularization pathologic PET/CT urothelial carcinoma bladder cancer upper tract urothelial carcinoma survival PET PSMA prostate DCFPyL DCFBC PSMA-1007 ovarian cancer relapse SUVmax targeted therapy prognosis soft tissue sarcoma (STS) pazopanib dynamic 18F-FDG PET/CT SUV two-tissue compartment model magnetic resonance imaging machine learning diffusion perfusion texture analysis squamous cell carcinoma of the head and neck diffusion-weighted imaging malignant pleural mesothelioma pleural dissemination empyema pleural effusion mCRPC SPECT/CT Computer-assisted diagnosis XOFIGO Therapy response assessment circulating miRNAs breast cancer imaging parameters PET/MRI biomarkers triple negative breast cancer VCAM-1 SPECT imaging sdAbs Hounsfield unit computed tomography adipose tissue precision oncology FDG-PET/CT PERCIST metastatic breast cancer prostate cancer 18F-FACBC recurrence meta-analysis review meningioma somatostatin receptor neuroimaging radionuclide therapy breast imaging marker radiomics Yin Yang 1 PDAC Mesothelin noninvasive imaging receptor status molecular imaging nuclear medicine guidelines overutilization epistemology consensus mantle cell lymphoma 18F-FDG PET/CT Deauville criteria Radium-223 FDG castrate resistant prostate cancer programmed cell death 1 receptor diagnostic imaging CTLA-4 Antigen Immunotherapy Adoptive radioactive tracers radionuclide imaging CD8-Positive T-Lymphocytes PI-RADS diffusion kurtosis imaging dynamic contrast-enhanced magnetic resonance imaging 68Gallium-PSMA PET/CT prostate-specific-antigen PSA kinetics thresholds biochemical recurrence optimal cutoff level non-small-cell lung cancer circulating tumor cells immunotherapy response to treatment head and neck cancer HPV EBV p16 Molecular imaging miRNA expression radiogenomics radiomic diagnosis biomarker glioblastoma radiation therapy MRI diffusion tensor imaging Hodgkin lymphoma diffuse large B-cell lymphoma staging response assessment locally advanced cervical cancer concurrent chemoradiotherapy treatment response follow up cystic tumor International Consensus Guidelines intraductal papillary mucinous neoplasms pancreatic neoplasms PD-1 PD-L1 response to therapy NSCLC positron-emission tomography single-photon emission computed tomography immune checkpoint inhibitors gold nanoparticle heat shock protein 70 spectral-CT |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557432103321 |
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Fanti Stefano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of Medical Imaging in Cancers . Volume 2
| Role of Medical Imaging in Cancers . Volume 2 |
| Autore | Fanti Stefano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (228 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
positron emission tomography
head and neck neoplasms neovascularization pathologic PET/CT urothelial carcinoma bladder cancer upper tract urothelial carcinoma survival PET PSMA prostate DCFPyL DCFBC PSMA-1007 ovarian cancer relapse SUVmax targeted therapy prognosis soft tissue sarcoma (STS) pazopanib dynamic 18F-FDG PET/CT SUV two-tissue compartment model magnetic resonance imaging machine learning diffusion perfusion texture analysis squamous cell carcinoma of the head and neck diffusion-weighted imaging malignant pleural mesothelioma pleural dissemination empyema pleural effusion mCRPC SPECT/CT Computer-assisted diagnosis XOFIGO Therapy response assessment circulating miRNAs breast cancer imaging parameters PET/MRI biomarkers triple negative breast cancer VCAM-1 SPECT imaging sdAbs Hounsfield unit computed tomography adipose tissue precision oncology FDG-PET/CT PERCIST metastatic breast cancer prostate cancer 18F-FACBC recurrence meta-analysis review meningioma somatostatin receptor neuroimaging radionuclide therapy breast imaging marker radiomics Yin Yang 1 PDAC Mesothelin noninvasive imaging receptor status molecular imaging nuclear medicine guidelines overutilization epistemology consensus mantle cell lymphoma 18F-FDG PET/CT Deauville criteria Radium-223 FDG castrate resistant prostate cancer programmed cell death 1 receptor diagnostic imaging CTLA-4 Antigen Immunotherapy Adoptive radioactive tracers radionuclide imaging CD8-Positive T-Lymphocytes PI-RADS diffusion kurtosis imaging dynamic contrast-enhanced magnetic resonance imaging 68Gallium-PSMA PET/CT prostate-specific-antigen PSA kinetics thresholds biochemical recurrence optimal cutoff level non-small-cell lung cancer circulating tumor cells immunotherapy response to treatment head and neck cancer HPV EBV p16 Molecular imaging miRNA expression radiogenomics radiomic diagnosis biomarker glioblastoma radiation therapy MRI diffusion tensor imaging Hodgkin lymphoma diffuse large B-cell lymphoma staging response assessment locally advanced cervical cancer concurrent chemoradiotherapy treatment response follow up cystic tumor International Consensus Guidelines intraductal papillary mucinous neoplasms pancreatic neoplasms PD-1 PD-L1 response to therapy NSCLC positron-emission tomography single-photon emission computed tomography immune checkpoint inhibitors gold nanoparticle heat shock protein 70 spectral-CT |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557309503321 |
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Fanti Stefano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
| Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression |
| Autore | Stefanachi Angela |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
EGR-1
flavonoid (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile MDA-MB-231 MMP9 TNFα pancreatic ductal adenocarcinoma cyclodextrin inclusion complex phase solubility studies preformulation studies biphenylnicotinamide derivatives dual inhibitor EGFR VEGFR2 ligand-based pharmacophore molecular docking molecular dynamics leukemias doxorubicin inflammation drug delivery tumor targeting elastin-like polypeptide cell penetrating peptide matrix metalloproteinase doxorubicin resistance photosensitizer delivery system PAMAM dendrimer photodynamic therapy cytotoxicity phototoxicity colorectal adenocarcinoma dicarboximides chemical synthesis apoptosis kinases anticancer gene profiling SAR biomarkers colorectal cancer early detection examination liquid biopsy personalized medicine tumor treatment exosomes ctDNA CTC cytotoxic activity pyrazole derivatives MTT assay ADMET analysis single-crystal diffraction FTIR spectroscopy NMR spectroscopy thermogravimetric analysis acute myelogenous leukemia platelets microparticles γδ T cells immunotherapy tumor resistance combination therapy tumor microenvironment immune checkpoint inhibitor neuroblastoma molecular iodine cyclophosphamide xenografts metronomic therapy tamoxifen CYP2D6 MCF-7 Ishikawa cells SERM TNBC uterotrophic α-mangostin poly(amidoamine) dendrimer targeted drug delivery biotin targeting glioblastoma multiforme squamous cell carcinoma antiparasitic therapy diclofenac indomethacin oleanolic acid derivative conjugates NF-κB Nrf2 MAPKs PSN-1 cells reactive oxygen species glioblastoma brain tumor extracellular vesicles pancreatic cancer paclitaxel clathrin endocytosis sulforaphane nicotine metalloproteinase-9 gastric cancer cell invasion Arylquin 1 colon cancer tumor progression azelastine oxidative stress autophagy mitotic catastrophe chronic myeloid leukemia imatinib tyrosine kinase ketoconazole P-glycoprotein drug efflux transporter non-small-cell lung cancer cisplatin resistance aldehyde dehydrogenase isothiocyanates disulfiram epithelial to mesenchymal transition aminopeptidase N acetamidophenones Schiff bases semicarbazones thiosemicarbazones inhibition of proliferation |
| ISBN | 3-0365-5927-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639990003321 |
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Stefanachi Angela
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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