Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Molecular diagnostics [[electronic resource] /] / edited by George Patrinos, Wilhelm Ansorge
| Molecular diagnostics [[electronic resource] /] / edited by George Patrinos, Wilhelm Ansorge |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | London, : Academic, 2010 |
| Descrizione fisica | 1 online resource (617 p.) |
| Disciplina | 616.0756 |
| Altri autori (Persone) |
PatrinosGeorge P
AnsorgeWilhelm <1944-> |
| Soggetto topico |
Molecular diagnosis
Genetic screening |
| ISBN |
1-282-73741-4
9786612737411 0-08-092318-6 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Molecular Diagnostics; Copyright Page; Contents; List of Contributors; Preface - First Edition; Preface - Second Edition; Foreword - First Edition; Chapter 1. Molecular Diagnostics: Past, Present, and Future; 1.1 INTRODUCTION; 1.2 HISTORY OF MOLECULAR DIAGNOSTICS: INVENTING THE WHEEL; 1.3 THE PCR REVOLUTION: GETTING MORE OUT OF LESS; 1.4 MOLECULAR DIAGNOSTICS IN THE POST-GENOMIC ERA; 1.5 FUTURE PERSPECTIVES: WHAT LIES BEYOND; 1.6 CONCLUSIONS; REFERENCES; Section I. Molecular Diagnostic Technology; Chapter 2. Allele-Specific Mutation Detection; 2.1 INTRODUCTION; 2.2 PCR-ARMS
2.3 PCR-ASO2.4 THE COMPETITIVE OLIGOPRIMING ASSAY; 2.5 CONCLUSIONS; REFERENCES; Chapter 3. Enzymatic and Chemical Cleavage Methods to Identify Genetic Variation; 3.1 INTRODUCTION; 3.2 CHEMICAL PROPERTIES OF MISMATCHES; 3.3 CHEMICAL CLEAVAGE OF MISMATCH METHOD FOR MUTATION DETECTION; 3.4 ADVANTAGES AND LIMITATIONS; 3.5 ENZYMATIC CLEAVAGE OF MISMATCH METHODS; 3.6 CONCLUSIONS; REFERENCES; Chapter 4. Mutation Detection by Single Strand Conformation Polymorphism and Heteroduplex Analysis; 4.1 INTRODUCTION; 4.2 PRINCIPLES OF SINGLE STRAND CONFORMATION POLYMORPHISM ANALYSIS 4.3 FLUORESCENT SINGLE STRAND CONFORMATION POLYMORPHISM ANALYSIS4.4 PARAMETERS INFLUENCING SINGLE STRAND CONFORMATION POLYMORPHISM ANALYSIS; 4.5 HETERODUPLEX ANALYSIS FOR MUTATION DETECTION; 4.6 SENSITIVITY AND LIMITATIONS; 4.7 DETECTION OF THE UNDERLYING GENOMIC VARIATION USING SSCP AND HDA; 4.8 CONCLUSIONS AND FUTURE ASPECTS; REFERENCES; Chapter 5. Capillary Electrophoresis; 5.1 INTRODUCTION; 5.2 HISTORY, PRINCIPLE, AND POTENTIAL APPLICATIONS OF CAPILLARY ELECTROPHORESIS; 5.3 CAPILLARY ELECTROPHORESIS IN MOLECULAR DIAGNOSTICS; 5.4 MODES OF APPLICATION; 5.5 SPECIFIC DIAGNOSTIC APPLICATIONS 5.6 FUTURE IMPROVEMENTSREFERENCES; Chapter 6. Temperature and Denaturing Gradient Gel Electrophoresis; 6.1 INTRODUCTION; 6.2 THE THEORY OF TEMPERATURE-GRADIENT GEL ELECTROPHORESIS; 6.3 THE PRACTICE OF TEMPERATURE GRADIENT GEL ELECTROPHORESIS; 6.4 DENATURING GRADIENT GEL ELECTROPHORESIS (DGGE); 6.5 THE USE OF TGGE/DGGE FOR MUTATION DETECTION; 6.6 DETECTION RATE AND SENSITIVITY; 6.7 RELATED TECHNIQUES AND VARIANTS; 6.8 TECHNICAL EQUIPMENT FOR TGGE/DGGE; 6.9 APPLICATIONS OF TGGE/DGGE AND RELATED METHODS; 6.10 CONCLUSIONS; ACKNOWLEDGEMENTS; REFERENCES Chapter 7. Real-Time Polymerase Chain Reaction7.1 HISTORY OF PCR; 7.2 PRINCIPLE OF REAL-TIME PCR; 7.3 REAL-TIME THERMAL CYCLERS; 7.4 HOW DATA ARE OBTAINED; 7.5 HOW DATA ARE QUANTIFIED; 7.6 MULTIPLEX REAL-TIME PCR; 7.7 APPLICATIONS IN MOLECULAR DIAGNOSTICS; 7.8 CRITERIA FOR DEVELOPING REAL-TIME PCR ASSAYS; 7.9 CONCLUSIONS; REFERENCES; Chapter 8. Pyrosequencing; 8.1 INTRODUCTION; 8.2 TECHNOLOGY; 8.3 APPLICATIONS; 8.4 CONCLUSIONS; ACKNOWLEDGEMENTS; REFERENCES; Chapter 9. Application of Padlock and Selector Probes in Molecular Medicine; 9.1 INTRODUCTION; 9.2 PADLOCK AND SELECTOR PROBES 9.3 APPLICATION OF PADLOCK AND MOLECULAR INVERSION PROBES FOR GENOTYPING |
| Record Nr. | UNINA-9910791285803321 |
| London, : Academic, 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular diagnostics [[electronic resource] /] / edited by George P. Patrinos, Wilhelm Ansorge
| Molecular diagnostics [[electronic resource] /] / edited by George P. Patrinos, Wilhelm Ansorge |
| Pubbl/distr/stampa | Amsterdam ; ; London, : Elsevier Academic Press, 2005 |
| Descrizione fisica | 1 online resource (477 p.) |
| Disciplina | 616.0756 |
| Altri autori (Persone) |
PatrinosGeorge P
AnsorgeWilhelm <1944-> |
| Soggetto topico |
Molecular diagnosis
Genetic screening |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-96693-9
9786610966936 0-08-047350-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
List of Contributors; Foreword; Preface; CHAPTER 1: Molecular Diagnostics: Past,Present,and Future; SECTION 1: Molecular Diagnostic Technology; CHAPTER 2: Allele-Specific Mutation Detection by PCR-ARMS and PCR-ASO; CHAPTER 3: Competitive Oligopriming; CHAPTER 4: Oligonucleotide Ligation Assays for the Diagnosis of Inherited Diseases; CHAPTER 5: Enzymatic and Chemical Cleavage Methods to Identify Genetic Variation; CHAPTER 6: Mutation Detection by Single Strand Conformation Polymorphism and Heteroduplex Analysis; CHAPTER 7: Capillary Electrophoresis
CHAPTER 8: Temperature and Denaturing Gradient Gel ElectrophoresisCHAPTER 9: Two-Dimensional Gene Scanning; CHAPTER 10: Real-Time Polymerase Chain Reaction; CHAPTER 11: Pyrosequencing; CHAPTER 12: Molecular Cytogenetics in Molecular Diagnostics; CHAPTER 13: Detection of Genomic Duplications and Deletions; CHAPTER 14: Analysis of Human Splicing Defects Using Hybrid Minigenes; CHAPTER 15: DNA Microarrays and Genetic Testing; CHAPTER 16: Human Genome Microarray in Biomedical Applications; CHAPTER 17: Use of High Throughput Mass Spectrographic Methods to Identify Disease Processes CHAPTER 18: The Application of Proteomics to Disease DiagnosticsSECTION II: Applications of Molecular Diagnostics and Related Issues; CHAPTER 19: Identification of Genetically Modified Organisms; CHAPTER 20: Pharmacogenetics and Pharmacogenomics: Impact on Drug Discovery and Development; CHAPTER 21: Molecular Diagnostic Applications in Forensic Science; CHAPTER 22: Molecular Diagnostics and Comparative Genomics in Clinical Microbiology; CHAPTER 23: Preimplantation Genetic Diagnosis; CHAPTER 24: Genetic Monitoring of Laboratory Animals CHAPTER 25: The Use of Locus-Specific Databases in Molecular DiagnosticsCHAPTER 26: Safety Analysis in Retroviral Gene Therapy: Identifying Virus Integration Sites in Gene-Modified Cells; CHAPTER 27: Automated DNA Hybridization and Detection; CHAPTER 28: The Use of Microelectronic-Based Techniques in Molecular Diagnostic Assays; CHAPTER 29: Miniaturization Technologies for Molecular Diagnostics; CHAPTER 30: Human Gene Patents and Genetic Testing; CHAPTER 31: Genetic Counselling and Ethics in Molecular Diagnostics; CHAPTER 32: Genetic Testing and Psychology CHAPTER 33: Safety in Biomedical and Other LaboratoriesCHAPTER 34: Quality Management in the Laboratory; Glossary; Index |
| Record Nr. | UNINA-9910458092203321 |
| Amsterdam ; ; London, : Elsevier Academic Press, 2005 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular diagnostics / / edited by George P. Patrinos, Wilhelm Ansorge
| Molecular diagnostics / / edited by George P. Patrinos, Wilhelm Ansorge |
| Pubbl/distr/stampa | Amsterdam ; ; London, : Elsevier Academic Press, 2005 |
| Descrizione fisica | 1 online resource (477 pages) |
| Disciplina | 616.0756 |
| Altri autori (Persone) |
PatrinosGeorge P
AnsorgeWilhelm <1944-> |
| Soggetto topico |
Molecular diagnosis
Genetic screening |
| ISBN |
1-280-96693-9
9786610966936 0-08-047350-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
List of Contributors; Foreword; Preface; CHAPTER 1: Molecular Diagnostics: Past,Present,and Future; SECTION 1: Molecular Diagnostic Technology; CHAPTER 2: Allele-Specific Mutation Detection by PCR-ARMS and PCR-ASO; CHAPTER 3: Competitive Oligopriming; CHAPTER 4: Oligonucleotide Ligation Assays for the Diagnosis of Inherited Diseases; CHAPTER 5: Enzymatic and Chemical Cleavage Methods to Identify Genetic Variation; CHAPTER 6: Mutation Detection by Single Strand Conformation Polymorphism and Heteroduplex Analysis; CHAPTER 7: Capillary Electrophoresis
CHAPTER 8: Temperature and Denaturing Gradient Gel Electrophoresis; CHAPTER 9: Two-Dimensional Gene Scanning; CHAPTER 10: Real-Time Polymerase Chain Reaction; CHAPTER 11: Pyrosequencing; CHAPTER 12: Molecular Cytogenetics in Molecular Diagnostics; CHAPTER 13: Detection of Genomic Duplications and Deletions; CHAPTER 14: Analysis of Human Splicing Defects Using Hybrid Minigenes; CHAPTER 15: DNA Microarrays and Genetic Testing; CHAPTER 16: Human Genome Microarray in Biomedical Applications; CHAPTER 17: Use of High Throughput Mass Spectrographic Methods to Identify Disease Processes CHAPTER 18: The Application of Proteomics to Disease Diagnostics; SECTION II: Applications of Molecular Diagnostics and Related Issues; CHAPTER 19: Identification of Genetically Modified Organisms; CHAPTER 20: Pharmacogenetics and Pharmacogenomics: Impact on Drug Discovery and Development; CHAPTER 21: Molecular Diagnostic Applications in Forensic Science; CHAPTER 22: Molecular Diagnostics and Comparative Genomics in Clinical Microbiology; CHAPTER 23: Preimplantation Genetic Diagnosis; CHAPTER 24: Genetic Monitoring of Laboratory Animals CHAPTER 25: The Use of Locus-Specific Databases in Molecular Diagnostics; CHAPTER 26: Safety Analysis in Retroviral Gene Therapy: Identifying Virus Integration Sites in Gene-Modified Cells; CHAPTER 27: Automated DNA Hybridization and Detection; CHAPTER 28: The Use of Microelectronic-Based Techniques in Molecular Diagnostic Assays; CHAPTER 29: Miniaturization Technologies for Molecular Diagnostics; CHAPTER 30: Human Gene Patents and Genetic Testing; CHAPTER 31: Genetic Counselling and Ethics in Molecular Diagnostics; CHAPTER 32: Genetic Testing and Psychology; CHAPTER 33: Safety in Biomedical and Other Laboratories; CHAPTER 34: Quality Management in the Laboratory; Glossary; Index |
| Record Nr. | UNINA-9910784568103321 |
| Amsterdam ; ; London, : Elsevier Academic Press, 2005 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pharmacogenetics Research and Clinical Applications: An International Landscape of the Accomplishments, Challenges, and Opportunities
| Pharmacogenetics Research and Clinical Applications: An International Landscape of the Accomplishments, Challenges, and Opportunities |
| Autore | Zgheib Nathalie K |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (122 p.) |
| Soggetto topico |
Pharmacology
Science: general issues |
| Soggetto non controllato |
challenges
clinical international pharmacogenetics (PGN) pharmacogenomics (PGx) research |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Pharmacogenetics Research and Clinical Applications |
| Record Nr. | UNINA-9910557642503321 |
Zgheib Nathalie K
|
||
| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||