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Biomarkers in Cancer [[electronic resource] /] / edited by Victor R. Preedy, Vinood B. Patel
Biomarkers in Cancer [[electronic resource] /] / edited by Victor R. Preedy, Vinood B. Patel
Pubbl/distr/stampa Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2020
Descrizione fisica 1 online resource (800 p. 50 illus.)
Disciplina 614.5999
Collana Biomarkers in Disease: Methods, Discoveries and Applications
Soggetto topico Cancer research
Oncology  
Pharmacology
Cancer Research
Oncology
Pharmacology/Toxicology
ISBN 94-007-7744-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910349266803321
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2020
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Biomarkers in Cancer [[electronic resource] /] / edited by Victor R. Preedy, Vinood B. Patel
Biomarkers in Cancer [[electronic resource] /] / edited by Victor R. Preedy, Vinood B. Patel
Edizione [1st ed. 2015.]
Pubbl/distr/stampa Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2015
Descrizione fisica 1 online resource (180 illus., 134 illus. in color. eReference.)
Disciplina 616.9940756
Collana Biomarkers in Disease: Methods, Discoveries and Applications
Soggetto topico Cancer research
Oncology  
Pharmacology
Cancer Research
Oncology
Pharmacology/Toxicology
ISBN 94-007-7681-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Intro -- Preface -- Series Preface -- Contents -- About the Editors -- Editorial Advisors -- Contributors -- Part I: General Aspects: Techniques and Overviews -- 1 OMICS for Tumor Biomarker Research -- Key Facts of OMICS Sciences -- Definitions of Words and Terms -- Introduction: A Role of OMICS in Cancer Biomarker Research -- An Analysis Pathway for Multiplex Biomarker Panels -- Transcriptome Profiling Approaches and Multiplexed Panels Based on mRNA Levels -- Proteomics: From MALDI-TOF Through Shotgun Techniques to Targeted Approach -- Metabolomics: A Promising New Direction for Biomarker Discovery -- Potential Applications to Prognosis, Other Diseases, or Conditions -- Conclusion -- Summary Points -- References -- 2 Circulating Tumor Cells as Biomarkers in Cancer -- Key Facts About Circulating Tumor Cells (CTCs) -- Definition of Words and Terms -- Introduction to Circulating Tumor Cells -- Detection of CTCs by RT-PCR -- CTC Enrichment Technologies -- Enrichment by Physical Properties -- Cell Surface Marker-Based Enrichment -- Emerging Technologies -- Microfluidic Devices -- High-Definition CTC -- DEParray -- Positive Versus Negative Enrichment of CTCs -- Quantification of CTCs as a Predictor of Survival and a Marker of Therapy Response -- CTC Characterization and Monitoring Therapy Responses -- Concluding Remarks -- Summary Points -- References -- 3 Oncoproteomic Approaches to Cancer Marker Discovery: The Case of Colorectal Cancer -- Key Facts -- Definition of Words and Terms -- Introduction -- Colorectal Cancer -- Biomarkers in Cancer -- Why Proteomics? -- Proteomic Technologies -- Two-Dimensional Gel Electrophoresis -- Gel-Free Proteomics: Isotopic Labeling -- Label-Free Mass Spectrometry -- Detection of Post-Translational Modifications -- Early Detection Screening Technologies and Samples for CRC Biomarker Research.
Protein Biomarkers of Colon Cancer -- Carcinoembryonic Antigen -- Fecal Hemoglobin -- Potential Application of Proteomics to Prognosis, Other Diseases, or Conditions -- Summary Points -- References -- 4 Cancer Cardiotoxicity and Cardiac Biomarkers -- Definition of Words and Terms -- Introduction -- Cardiotoxicity of Cancer Therapy -- Summary Points -- Key Facts of Cardiotoxicity -- Chemotherapeutic Agents -- Anthracycline -- Targeted Therapy -- Trastuzumab -- Inhibitors of Angiogenesis -- Summary Points -- Key Facts of Chemotherapeutic Agents -- Monitoring of Drug-Induced Cardiotoxicity -- Cardiac Imaging -- Serological Markers -- Summary Points -- Key Facts of Monitoring of Drug-Induced Cardiotoxicity -- Troponins -- Summary Points -- Key Facts of Troponin -- Natriuretic Peptides -- Summary Points -- Key Facts of Natriuretic Peptide -- Potential Application to Prognosis and Other Disease Conditions -- Summary Points -- Key Facts of Potential Application to Prognosis and Other Disease Conditions -- References -- 5 DNA Methylation as a Biomarker in Cancer -- Key Facts -- Key Facts of DNMT: DNA Methyltransferase -- Key Facts of CGIs: CpG Islands -- Key Facts of MBD Proteins: Methyl-CpG-Binding-Domain Proteins -- Definitions of Words and Terms -- Introduction -- DNA Methylation in Normal Cells -- Relationship Between CGI DNA Methylation and Transcriptional Repression -- DNA Methylation in Cancer Cells -- 5-Hydroxymethylcytosine and Its Derivatives in Cancer -- Long-Range Coordinated Disruptions in DNA Methylation -- CpG Island Methylator Phenotype -- Methods of Isolating DNA Methylation Biomarkers in Cancer -- DNA Methylation Changes in Early Tumorigenesis -- The Suitability of DNA Methylation Changes as Biomarkers -- DNA Methylation as Early Detection Biomarkers -- DNA Methylation Biomarkers for Prediction of Drug Sensitivity -- Future Perspectives.
Potential Applications to Prognosis, Other Diseases, or Conditions -- Summary Points -- References -- 6 Kallikreins as Biomarkers in Human Malignancies -- Key Facts on Kallikrein Family -- Definitions of Words and Terms -- Introduction -- KLK Family: A Rich Source of Cancer Biomarkers -- Prostate Cancer -- Prostate-Specific Antigen (PSA/KLK3): A Long-Used yet Disputed Biomarker for CaP Screening and Diagnosis -- PSA/KLK3: Applications in CaP Patients´ Treatment Monitoring and Prediction of Clinical Outcome -- Emerging Biomarkers in Prostate Cancer from the Kallikrein Family: Can They Follow and/or Enrich the Success of PSA/KLK3? -- Diagnostic Significance -- Prostate Cancer Prognosis -- Ovarian Cancer -- KLK6, KLK10, and Other KLK Family Members as Promising Markers in Ovarian Cancer Diagnosis -- KLKs with Potential Prognostic and/or Predictive Value in Ovarian Cancer -- Breast Cancer -- KLKs with Diagnostic Significance for Breast Cancer -- Prognosis and Treatment Monitoring -- Endometrial and Cervical Cancer -- KLKs with Potential Clinical Utility in Endometrial Carcinomas -- KLKs with Potential Clinical Utility in Cervical Cancer -- Renal Cell Carcinoma and Urinary Bladder Cancer -- KLKs with Potential Clinical Utility in RCC and Bladder Cancer -- Gastric and Colon Cancer -- KLKs with Potential Clinical Utility in Gastric Cancer -- KLKs with Potential Clinical Utility in Colon Cancer -- Other Types of Human Cancer -- KLK-Targeting MicroRNAs: A New Era in Cancer Research Has Just Begun -- Single-Nucleotide Polymorphisms (SNPs) in the Human KLK Locus -- Methodologies and Analytical Techniques -- Potential Applications of KLK Family Members to Prognosis, Nonmalignant Diseases, or Conditions -- KLKs and CNS Disorders -- KLKs in Skin Disorders -- Conclusions -- Summary Points -- References -- 7 MAP17 as Biomarker for Cancer Treatment -- Key Facts.
Definitions of Words and Terms -- Introduction -- MAP17 (PDZK1IP1) -- MAP17 in Human Tumors -- Oncogenic Activity of MAP17 -- Potential Applications to Prognosis, Diagnosis, or Response to Therapy -- Summary Points -- References -- 8 CA 19-9 as a Serum Biomarker in Cancer -- Definitions of Words and Terms -- Introduction -- CA 19-9 Measurement Methodology -- CA 19-9 and Its Utility in Pancreatic Cancer -- Epidemiology of Pancreas Cancer -- CA 19-9 Level as a Diagnostic Marker/Screening Tool in Pancreatic Cancer -- CA 19-9 Level as a Prognostic Marker in Resectable Pancreatic Adenocarcinoma -- CA 19-9 Level as a Prognostic Marker in Advanced and Metastatic Pancreatic Adenocarcinoma -- CA 19-9 in Intraductal Papillary Mucinous Neoplasms of the Pancreas -- CA 19-9 in Gastric Cancer -- CA 19-9 in Biliary Tract Cancers -- CA 19-9 in Colorectal Cancer -- CA 19-9 in Ovarian Cancer -- Utility in Other Malignancies -- CA 19-9 in Occult Primary -- Potential Applications to Prognosis, Other Diseases, or Conditions -- Summary Points -- References -- 9 PTTG (Securin) as Cancer Biomarker -- Key Facts of Pituitary Gland -- Definitions of Words and Terms -- Introduction -- Discovery of the Pituitary Tumor Transforming Gene -- PTTG in Cancer -- PTTG Is an Oncogene -- Basic Molecular PTTG Functions in Cancer not Restricted to Pituitary Adenomas -- Role in Genetic Instability -- Role as a Broad Regulator of the Transcriptome -- Motility, Invasion, and Metastasis -- Epidermal to Mesenchymal Transition -- Clinical Impact of PTTG -- PTTG as a Prognostic Marker -- Cellular Proliferation -- Vascular Proliferation -- Migratory Ability of Tumor Cells -- Perspectives for a Prognostic Application of PTTG in Clinical Practice -- Therapeutic Aspects -- Concluding Remarks -- Summary Points -- References -- 10 U2 Small Nuclear RNA as a Biomarker in Cancer.
Key Facts of Noncoding RNAs as Biomarkers -- Definition of Words and Terms -- Introduction -- U2 snRNA and the Splicing Process of Pre-mRNAs -- Genomic Organization and Sequence Characteristics of U2 snRNA -- RNU2-1 Fragment Biogenesis and Stability -- RNU2-1f in Serum of Pancreatic and Colorectal Cancer Patients -- RNU2-1f in Lung Cancer -- RNU2-1f as Biomarker in Other Cancer Types -- Potential Applications of RNU2-1f Tests to Prognosis, Other Diseases, or Conditions -- Summary Points -- References -- Part II: Bladder, Kidney, Liver and Lung -- 11 Centrosome Amplification as Biomarkers in Bladder Cancer Using Touch Biopsy and Bladder Washing Cytological Specimens -- Key Facts of Centrosome Amplification -- Definitions of Words and Terms -- Introduction -- Mechanism of Centrosome Amplification -- Copy Number Aberrations and Centrosome Amplification -- Clinical Significance of Centrosome Amplification -- Other Biomarkers Using Urine (Bladder Washing Cytology) -- Potential Applications to Prognosis -- Conclusion -- Summary Points -- References -- 12 Microarrays and Renal Cell Cancer Biomarkers -- Key Facts of Renal Cell Carcinoma -- Definitions of Words and Terms -- Introduction -- Genomic Approaches -- Array-Based CGH (aCGH) and SNP Arrays for Tracking Potential Chromosomal and Gene Marker Loci -- DNA Methylation Arrays for Unmasking Silenced RCC Markers -- Transcriptomic Approaches -- DNA Microarrays for Screening RCC-Specific Marker Expression Patterns -- miRNA Microarrays for Identifying RCC Key Players of Gene Regulation -- Proteomic Approaches -- Tissue Microarrays (TMA) for Evaluating Molecular Markers with Clinical Relevance in RCC -- Combinations of Microarray Platforms Used to Validate Potential Biomarkers in RCC -- Potential Applications to Prognosis, Other Diseases, or Conditions -- Summary Points -- References.
13 Immunogenic Cell Death Markers in Liver Cancer.
Record Nr. UNINA-9910298270203321
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2015
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Biomarkers in Cardiovascular Disease [[electronic resource] /] / edited by Vinood B. Patel, Victor R. Preedy
Biomarkers in Cardiovascular Disease [[electronic resource] /] / edited by Vinood B. Patel, Victor R. Preedy
Pubbl/distr/stampa Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2020
Descrizione fisica 1 online resource (Approx. 800 p. 50 illus.)
Disciplina 614.5999
Collana Biomarkers in Disease: Methods, Discoveries and Applications
Soggetto topico Cancer research
Oncology  
Pharmacology
Cancer Research
Oncology
Pharmacology/Toxicology
ISBN 94-007-7741-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cardiolog -- Addictions -- Immunology -- Birth Defects -- Genetics.
Record Nr. UNINA-9910349266203321
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2020
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Biomarkers in Cardiovascular Disease [[electronic resource] /] / edited by Vinood B. Patel, Victor R. Preedy
Biomarkers in Cardiovascular Disease [[electronic resource] /] / edited by Vinood B. Patel, Victor R. Preedy
Edizione [1st ed. 2016.]
Pubbl/distr/stampa Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2016
Descrizione fisica 1 online resource (213 illus., 138 illus. in color. eReference.)
Disciplina 616.107
Collana Biomarkers in Disease: Methods, Discoveries and Applications
Soggetto topico Cancer research
Oncology  
Pharmacology
Cancer Research
Oncology
Pharmacology/Toxicology
ISBN 94-007-7678-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto High-Throughput Approaches to Biomarker Discovery and Challenges of Subsequent Validation -- Mass Spectrometry-Based Lipidomics for Biomarker Research -- Flow Cytometry as Platform for Biomarker Discovery and Clinical Validation -- Pentraxin 3 as Biomarker -- Isoprostanes as Biomarkers of Disease and Early Biological Effect -- Fetal Membranes: Potential Source of Preterm Birth Biomarkers -- 1-Hydroxypyrene as a Biomarker for Environmental Health -- Biomarkers of Necrosis and Myocardial Remodeling -- Serum Heat Shock Proteins as Novel Biomarker for Heart -- Failure and Cardiovascular Diseases -- Traditional and Proteomic Biomarkers of Autosomal Dominant -- Polycystic Kidney Disease (ADPKD) -- Biomarker for Amyotrophic Lateral Sclerosis -- Biomarkers of Vector Bites: Arthropod Immunogenic Salivary Proteins in Vector-Borne Diseases Control -- Biomarkers of Graft-Versus-Host Disease.
Record Nr. UNINA-9910253896303321
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2016
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Biomarkers in Kidney Disease [[electronic resource] /] / edited by Vinood B. Patel, Victor R. Preedy
Biomarkers in Kidney Disease [[electronic resource] /] / edited by Vinood B. Patel, Victor R. Preedy
Pubbl/distr/stampa Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2020
Descrizione fisica 1 online resource (Approx. 800 p. 50 illus.)
Disciplina 614.5999
Collana Biomarkers in Disease: Methods, Discoveries and Applications
Soggetto topico Cancer research
Oncology  
Pharmacology
Cancer Research
Oncology
Pharmacology/Toxicology
ISBN 94-007-7743-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Endocrinology -- Addictions -- Immunology -- Genetics.
Record Nr. UNINA-9910349266503321
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2020
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Biomarkers in Kidney Disease [[electronic resource] /] / edited by Vinood B. Patel, Victor R. Preedy
Biomarkers in Kidney Disease [[electronic resource] /] / edited by Vinood B. Patel, Victor R. Preedy
Edizione [1st ed. 2016.]
Pubbl/distr/stampa Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2016
Descrizione fisica 1 online resource (208 illus., 150 illus. in color. eReference.)
Disciplina 616.9940072
Collana Biomarkers in Disease: Methods, Discoveries and Applications
Soggetto topico Cancer research
Oncology  
Pharmacology
Cancer Research
Oncology
Pharmacology/Toxicology
ISBN 94-007-7699-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Intro -- Volume Preface -- Series Preface -- Contents -- About the Editors -- Editorial Advisors -- Contributors -- Part I: General Aspects -- 1 Biomarkers in Kidney Transplantation -- Key Facts -- Key Facts of Operational Tolerance -- Key Facts of Costimulatory Signal -- Definitions -- Introduction -- Biomarkers of Allograft Rejection -- Urine Biomarkers -- Perforin, Granzyme B, and Fas-L mRNA -- Granzyme A mRNA -- Foxp3 mRNA -- Cytokine/Chemokine mRNA -- OX40/OX40-L mRNA -- mRNA Signature -- Urine miRNAs -- Urine Proteomics -- Blood Biomarkers -- CD30 -- Genomics -- miRNAs -- Biomarkers of -- Gene Expression Studies -- Potential Applications to Prognosis, Other Diseases, or Conditions -- Summary Points -- References -- 2 Diagnostic Biomarkers of Acute Kidney Injury in Newborns -- Key Facts of Diagnostic Biomarkers of Acute Kidney Injury in Newborns -- Definitions -- Introduction -- Biomarkers of Acute Kidney Injury -- Cystatin C -- Neutrophil Gelatinase-Associated Lipocalin -- Interleukin-18 -- Kidney Injury Molecule-1 -- Fibroblast Growth Factor-2 -- Urinary Epidermal Growth Factor -- Urine Metabolomic Profiling -- Discussion -- Conclusions -- Potential Applications to Prognosis, Other Diseases, or Conditions -- Summary Points -- References -- 3 Osmolal Gap as a Biomarker in Kidney Injury: Focusing on the Differential Diagnosis of Metabolic Acidosis -- Key Facts of the Osmolal Gap -- Definitions -- Introduction -- Definition -- Estimation of the Osmolal Gap -- Measured Osmolality -- Calculation of Osmolality -- Calculated Serum Osmolality -- Calculated Urine Osmolality -- Serum or Urine Osmolal Gap -- Clinical Utility of the Serum and Urine Osmolal Gap -- Serum Osmolal Gap -- Urine Osmolal Gap -- Limitations to the Clinical Utility of the Osmolal Gap -- Various Causes of an Osmolal Gap -- Limitations of Methods of Osmometry -- Summary Points.
References -- 4 Peritoneal Effluent Biomarker Discovery in Peritoneal Dialysis: The Omics Era -- Definitions -- Introduction -- Methodological Considerations -- Analytical Validity -- Study Designs and Population -- Omics Data Analysis -- Current Developments -- Proteomics -- Genomics and Metabolomics -- Potential Applications to Prognosis, Other Diseases, or Conditions -- Future Directions -- Summary Points -- References -- 5 Metabolomics and Stages of Chronic Kidney Disease -- Key Facts About Metabolomics and Stages of Chronic Kidney Disease -- Definitions -- Introduction -- Why Use Metabolomics to Diagnose CKD -- Using Mass Spectrometry for Metabolite Exploration -- Nontarget Analysis and Target Analysis -- Nontarget Analysis -- Target Analysis (Multi-target Analysis) -- Future of Metabolomics in the Diagnosis of Disease -- Potential Applications to Prognosis and Other Diseases and Conditions -- Summary Points -- References -- 6 Hypoxia as a Biomarker of Kidney Disease -- Key Facts of Kidney Oxygenation -- Definitions -- Introduction -- Chronic Kidney Disease -- The Role of Hypoxia in the Pathogenesis of Chronic Kidney Disease -- The Clinical Problem: Early Diagnosis and Instigation of Therapy -- Assessment of Kidney Oxygenation by BOLD MRI in Chronic Kidney Disease -- Acute Kidney Injury -- The Role of Hypoxia in the Pathogenesis of Acute Kidney Injury -- The Clinical Problem: Prevention of Acute Kidney Injury in the Hospital Setting -- Cardiac Surgery -- Sepsis -- Radiocontrast Agents and Other Nephrotoxins -- Urinary PO2 as a Diagnostic Biomarker in Acute Kidney Injury -- Potential Applications to Prognosis, Other Disease and Conditions -- Summary Points -- References -- 7 MicroRNAs in Kidney Diseases -- Key Facts -- Key Facts of Renal Physiology -- Key Facts of PKD -- Key Facts of Primary and Secondary Glomerulonephritis.
Key Facts of Kidney Transplantation -- Key Facts of miRNA Therapy -- Definitions -- Introduction: Biogenesis of miRNAs -- New Strategies for Detection of Renal miRNA -- MiRNAs in Renal Physiology -- Blood Flow and Oxygen Supply -- Glomerular Filtration -- Tubular Reabsorption and Excretion -- Interstitial Osmolarity -- MiRNAs in Polycystic Kidney Disease -- MiRNAs in Primary and Secondary Glomerulonephritis -- MiRNAs in Kidney Transplantation -- Potential Applications to Prognosis and Other Diseases or Conditions -- MiRNAs as Diagnostic Tools in Blood and Urine -- New Approaches for miRNA Therapy -- Therapeutic Approaches -- MiRNAs as Potential Therapeutic Strategies -- Challenges and Future Perspectives -- Summary Points -- References -- 8 Serum Creatinine Trajectories in Kidney Disease -- Key Facts -- Definitions -- Introduction -- Creatinine: Metabolism, Chemical Structure, and Excretion in the Urine -- Serum Creatinine Trajectories in Kidney Disease -- Serum Creatinine Trajectories in Acute Kidney Injury (AKI): The Rainbow Spectrum of Renal Outcomes Following AKI in CKD Patien... -- Rapid and Full Recovery of Renal Function Following AKI on CKD -- Partial Recovery of Renal Function Following AKI on CKD -- Rapid-Onset Yet Irreversible ESRD or the Syndrome of Rapid-Onset ESRD (SORO-ESRD) Following AKI on CKD in a Patient with Nativ... -- Rapid-Onset Yet Irreversible ESRD or the Syndrome of Rapid-Onset ESRD (SORO-ESRD) Following AKI on CKD in a Renal Transplant R... -- Serum Creatinine Trajectories in Adult Polycystic Kidney Disease (ADPKD): An Nnamdi Azikiwe University Teaching Hospital, New... -- Case I -- Case II -- Serum Creatinine Trajectories in Chronic Kidney Disease: The NKF KDOQI CKD Staging Paradigm Revisited: CKD Prediction Is an In... -- Stable CKD V Over 7Years in a Now 78-Year-Old Caucasian Hypertensive Diabetic Male.
Stable CKD IV Over 8Years in a Now 78-Year-Old Caucasian Hypertensive Diabetic Male -- Stable CKD III Over Nearly 10Years in a Now 87-Year-Old Caucasian Hypertensive Male -- Two Divergent Patterns of CKD to ESRD Progression: The ``Classic´´ Pattern and the Pattern of the Syndrome of Rapid-Onset End-... -- ``Classic´´ Pattern of CKD-ESRD Progression in a Hypertensive Caucasian Male -- ``Classic´´ Pattern of CKD-ESRD Progression in a Caucasian Hypertensive Diabetic Male -- Pattern of Syndrome of Rapid-Onset ESRD in a Caucasian Hypertensive Diabetic Male -- Late-Onset End-Stage Renal Failure from Angiotensin Blockade (LORFFAB) -- Serum Creatinine Trajectories in a Case of ``Quadruple Whammy´´ -- Perioperative AKI and Concurrent Angiotensin Inhibition Alone: A Case Presentation from Mayo Clinic Health System, Eau Claire,... -- Serum Creatinine Trajectories in HIV-Associated Nephropathy: An Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria, R... -- Case I -- Case II -- Serum Creatinine Trajectories in Sickle Cell Disease Nephropathy: An Nnamdi Azikiwe University Teaching Hospital, Nnewi, Niger... -- Conclusions: A Need for More Preventative Renal Medicine: Renoprevention Revisited. The Introduction of the New Innovative CKD... -- Potential Applications of Serum Creatinine Trajectories in Kidney Disease Prognostication and Management -- Summary Points -- References -- 9 Random Spot Urine Markers for Kidney and Their Applications -- Key Facts of Urinalysis -- Definitions -- Introduction -- The Specimen for Analysis -- Physical Markers -- Color -- Odor -- Turbidity or Clarity -- Relative Density -- Chemical Markers -- Blood -- pH -- Bilirubin -- Urobilinogen -- Ketones -- Nitrites and Leukocyte Esterase -- Glucose -- Albuminuria -- Protein -- Uric Acid -- Electrolytes -- Sodium -- Potassium -- Phosphate -- Others -- Microscopic Markers.
Erythrocytes -- Leukocytes -- Cells -- Lipids -- Casts -- Crystals -- Organisms -- Conclusions -- Potential Applications to Prognosis, Other Diseases, or Conditions -- Summary Points -- References -- 10 Overview of Neutrophil Gelatinase-Associated Lipocalin (NGAL) as a Biomarker in Nephrology -- Key Facts of Creatinine -- Definitions -- Introduction -- NGAL and Acute Kidney Injury -- NGAL and Autosomal-Dominant Polycystic Kidney Disease (ADPKD) -- NGAL and Chronic Kidney Disease -- NGAL in Kidney Transplant Patients -- Potential Applications to Prognosis and Other Diseases or Conditions -- Summary Points -- References -- 11 Chemokines as Potential Markers in Pediatric Renal Diseases -- Key Facts of Chemokines in Pediatric Renal Disease -- Definitions -- Chemokines: General Concepts -- Chemokines in Renal Diseases -- Chemokines in Glomerular Diseases -- Chemokines in Congenital Uropathies -- Ureteropelvic Junction Obstruction -- Vesicoureteral Reflux -- Potential Applications to Prognosis, Other Diseases or Conditions -- Summary Points -- References -- 12 Kidney and Neoplastic Disease: Overview with a Particular Interest to Interpretation of Cancer Biomarkers -- Key Facts of Renal Disease Subsequent to Neoplasia -- Key Facts of Neoplasia Risk in Renal Patients -- Key Facts of Neoplasia Risk in Renal Patients -- Definitions -- Introduction -- Renal Disease Associated with Malignancies -- Malignancy Associated with Renal Disease -- Breast Cancer -- Colorectal Cancer -- Women-Specific Tumoral Diseases: Cervical Cancer and Ovary Cancer -- Lung Cancer -- Liver Cancer -- Prostate Cancer -- Tumors of the Urinary Tract: Kidney, Ureters, and Bladder -- Markers of Cancer and Renal Function -- Conclusions -- Summary Points -- References -- Part II: Circulating and Body Fluid Biomarkers -- 13 Creatinine Assays in Early Infancy: How to Aim for a Moving Target.
Key Facts of Creatinine Assays and Their Clinical Relevance in Early Infancy.
Record Nr. UNINA-9910253896203321
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2016
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Lo trovi qui: Univ. Federico II
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Biomarkers in Liver Disease [[electronic resource] /] / edited by Vinood B. Patel, Victor R. Preedy
Biomarkers in Liver Disease [[electronic resource] /] / edited by Vinood B. Patel, Victor R. Preedy
Pubbl/distr/stampa Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2020
Descrizione fisica 1 online resource (800 p. 50 illus.)
Disciplina 614.5999
Collana Biomarkers in Disease: Methods, Discoveries and Applications
Soggetto topico Cancer research
Oncology  
Pharmacology
Cancer Research
Oncology
Pharmacology/Toxicology
ISBN 94-007-7742-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Liver biomarkers and their applications to nutritional interventions in animal studies -- AST-to-platelet ratio index (APRI) as marker in liver disease.-Inflammatory biomarkers in ascites -- Biomarkers for hepatocellular carcinoma in East Asia -- Liver disease and acylcarnitines as mechanistic biomarkers.-Type VI Collagen: Biological Functions and its Neo-epitope as Hepatic Fibrosis Biomarker -- Fibrinogen α-chain as a serum marker of liver disease -- Monocyte chemotactic protein-1 (cytokine, receptors,and gene polymorphisms) in hepatitis -- Biomarkers for Recurrence of Hepatocellular Carcinoma.-Graft-derived cell-free DNA as a biomarker in liver transplantation -- Serum sialic acid as a biomarker in liver disease -- CD133 and EpCAM as Biomarkers in Liver Diseases -- Traditional markers in liver disease -- Biomarkers of extracellular matrix remodeling in liver diseases -- Squamous Cell Carcinoma Antigen- Immunoglobulin M (SCCA-IgM) as biomarker in liver disease: biological aspects and clinical applications -- microRNA-155 and microRNA-196b in hepatitis C virus infection -- Immunological biomarkers in liver transplantation -- Phosphatidylethanol and alcohol use in liver disease patients -- Interaction of sialyltransferases, sialidases and sialic acids in liver diseases and applications to biomarker discovery -- Biomarkers to monitor graft function following liver transplantation -- YKL-40 as a biomarker of liver diseases -- Peripheral venous, portal venous, hepatic venous, arterial and intrahepatic cytokine levels as biomarkers and functional correlations -- Histological Biomarkers of Non-Alcoholic Fatty Liver Disease -- Vascular cell adhesion molecule-1 (vcam-1) expression in liver disease -- Bilirubin as a biomarker in liver disease -- Hydroxyproline as a biomarker in liver disease -- Genetic biomarkers of paracetamol-induced acute liver failure -- PNPLA3 polymorphism and Nonalcoholic Fatty Liver Disease -- Hepascore and it's application to liver disease -- Model for End-Stage Liver Disease (MELD) Score as a Biomarker -- Biomarkers in focus: Alanine Aminotransferase -- PTX3 as a biomarker of liver disease.
Record Nr. UNINA-9910349265903321
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2020
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Biosensors and environmental health / / editors, Victor R. Preedy, Vinood B. Patel
Biosensors and environmental health / / editors, Victor R. Preedy, Vinood B. Patel
Edizione [First edition.]
Pubbl/distr/stampa Boca Raton, Fla. : , : CRC Press, , 2012
Descrizione fisica 1 online resource (383 pages, 9 unnumbered pages of plates) : illustrations
Disciplina 610.28
Altri autori (Persone) PreedyVictor R
PatelVinood B
Soggetto topico Biosensors
Environmental health
Environmental toxicology
Pollution - Measurement
Soggetto genere / forma Electronic books.
ISBN 0-429-18834-X
1-4665-6566-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. Immunochips for personal toxicity testing / Zhixian Gao, Nan Liu and Rajkumar Rajendram -- 2. Detection of pesticide residues using biosensors / Javier Ramon-Azcon, Tomoyuki Yasukawa and Fumio Mizutani -- 3. Biosensors for ecotoxicity of xenobiotics : a focus on soil and risk assessment / Edoardo Puglisi. [et al.] -- 4. Biosensor-controlled degradation of organophosphate insecticides in water / Georges Istamboulie. [et al.] -- 5. Biosensors for endocrine disruptors : the case of bisphenol A and catechol / Marianna Portaccio. [et al.] -- 6. Biosensors for detection of heavy metals / Pavlina Sobrova. [et al.] -- 7. Whole cell biosensors : applications to environmental health / S. Buchinger and G. Reifferscheid -- 8. Bacterial whole cell bioreporters in environmental health / Yizhi Song. [et al.] -- 9. Environmental toxicology monitoring with polyazetidine-based enzymatic electrochemical biosensors / Franco Mazzei and Gabriele Favero -- 10. Polycyclic aromatic hydrocarbon (PAH) sensitive bacterial biosensors in environmental health / Mona Wells -- 11. Quorum sensing in microbial biosensors / Swati Choudhary and Claudia Schmidt-Dannert -- 12. Biosensors based on immobilization of proteins in supramolecular assemblies for the detection of environmental relevant analytes / Rosa Pilolli. [et al.] -- 13. Nanogravimetric and voltammetric DNA-biosensors for screening of herbicides and pesticides / Maria Hepel, Magdalena Stobiecka and Anna Nowicka -- 14. Nitrate determination by amperometric biosensors : applications to environmental health / Erol Akyilmaz and Victor R. Preedy -- 15. Antibody-based biosensors for small environmental pollutants : focusing on PAHs / Candace R. Spier, Michael A. Unger and Stephen L. Kaattari -- 16. Exoelectrogens-based electrochemical biosensor for environmental monitoring / Liu Deng, Li Shang and Shaojun Dong -- 17. Detecting waterborne parasites using piezoelectric cantilever biosensors / Sen Xu and Raj Mutharasan -- 18. Bioluminescence-based biosensor for food contamination / Jinping Luo. [et al.].
Record Nr. UNINA-9910464194303321
Boca Raton, Fla. : , : CRC Press, , 2012
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Biosensors and environmental health / / editors, Victor R. Preedy, Vinood B. Patel
Biosensors and environmental health / / editors, Victor R. Preedy, Vinood B. Patel
Edizione [First edition.]
Pubbl/distr/stampa Boca Raton, Fla. : , : CRC Press, , 2012
Descrizione fisica 1 online resource (383 pages, 9 unnumbered pages of plates) : illustrations
Disciplina 610.28
Altri autori (Persone) PreedyVictor R
PatelVinood B
Soggetto topico Biosensors
Environmental health
Environmental toxicology
Pollution - Measurement
ISBN 0-429-18834-X
1-4665-6566-7
Classificazione MED071000
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. Immunochips for personal toxicity testing / Zhixian Gao, Nan Liu and Rajkumar Rajendram -- 2. Detection of pesticide residues using biosensors / Javier Ramon-Azcon, Tomoyuki Yasukawa and Fumio Mizutani -- 3. Biosensors for ecotoxicity of xenobiotics : a focus on soil and risk assessment / Edoardo Puglisi. [et al.] -- 4. Biosensor-controlled degradation of organophosphate insecticides in water / Georges Istamboulie. [et al.] -- 5. Biosensors for endocrine disruptors : the case of bisphenol A and catechol / Marianna Portaccio. [et al.] -- 6. Biosensors for detection of heavy metals / Pavlina Sobrova. [et al.] -- 7. Whole cell biosensors : applications to environmental health / S. Buchinger and G. Reifferscheid -- 8. Bacterial whole cell bioreporters in environmental health / Yizhi Song. [et al.] -- 9. Environmental toxicology monitoring with polyazetidine-based enzymatic electrochemical biosensors / Franco Mazzei and Gabriele Favero -- 10. Polycyclic aromatic hydrocarbon (PAH) sensitive bacterial biosensors in environmental health / Mona Wells -- 11. Quorum sensing in microbial biosensors / Swati Choudhary and Claudia Schmidt-Dannert -- 12. Biosensors based on immobilization of proteins in supramolecular assemblies for the detection of environmental relevant analytes / Rosa Pilolli. [et al.] -- 13. Nanogravimetric and voltammetric DNA-biosensors for screening of herbicides and pesticides / Maria Hepel, Magdalena Stobiecka and Anna Nowicka -- 14. Nitrate determination by amperometric biosensors : applications to environmental health / Erol Akyilmaz and Victor R. Preedy -- 15. Antibody-based biosensors for small environmental pollutants : focusing on PAHs / Candace R. Spier, Michael A. Unger and Stephen L. Kaattari -- 16. Exoelectrogens-based electrochemical biosensor for environmental monitoring / Liu Deng, Li Shang and Shaojun Dong -- 17. Detecting waterborne parasites using piezoelectric cantilever biosensors / Sen Xu and Raj Mutharasan -- 18. Bioluminescence-based biosensor for food contamination / Jinping Luo. [et al.].
Record Nr. UNINA-9910789478103321
Boca Raton, Fla. : , : CRC Press, , 2012
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Biosensors and environmental health / / editors, Victor R. Preedy, Vinood B. Patel
Biosensors and environmental health / / editors, Victor R. Preedy, Vinood B. Patel
Edizione [First edition.]
Pubbl/distr/stampa Boca Raton, Fla. : , : CRC Press, , 2012
Descrizione fisica 1 online resource (383 pages, 9 unnumbered pages of plates) : illustrations
Disciplina 610.28
Altri autori (Persone) PreedyVictor R
PatelVinood B
Soggetto topico Biosensors
Environmental health
Environmental toxicology
Pollution - Measurement
ISBN 0-429-18834-X
1-4665-6566-7
Classificazione MED071000
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. Immunochips for personal toxicity testing / Zhixian Gao, Nan Liu and Rajkumar Rajendram -- 2. Detection of pesticide residues using biosensors / Javier Ramon-Azcon, Tomoyuki Yasukawa and Fumio Mizutani -- 3. Biosensors for ecotoxicity of xenobiotics : a focus on soil and risk assessment / Edoardo Puglisi. [et al.] -- 4. Biosensor-controlled degradation of organophosphate insecticides in water / Georges Istamboulie. [et al.] -- 5. Biosensors for endocrine disruptors : the case of bisphenol A and catechol / Marianna Portaccio. [et al.] -- 6. Biosensors for detection of heavy metals / Pavlina Sobrova. [et al.] -- 7. Whole cell biosensors : applications to environmental health / S. Buchinger and G. Reifferscheid -- 8. Bacterial whole cell bioreporters in environmental health / Yizhi Song. [et al.] -- 9. Environmental toxicology monitoring with polyazetidine-based enzymatic electrochemical biosensors / Franco Mazzei and Gabriele Favero -- 10. Polycyclic aromatic hydrocarbon (PAH) sensitive bacterial biosensors in environmental health / Mona Wells -- 11. Quorum sensing in microbial biosensors / Swati Choudhary and Claudia Schmidt-Dannert -- 12. Biosensors based on immobilization of proteins in supramolecular assemblies for the detection of environmental relevant analytes / Rosa Pilolli. [et al.] -- 13. Nanogravimetric and voltammetric DNA-biosensors for screening of herbicides and pesticides / Maria Hepel, Magdalena Stobiecka and Anna Nowicka -- 14. Nitrate determination by amperometric biosensors : applications to environmental health / Erol Akyilmaz and Victor R. Preedy -- 15. Antibody-based biosensors for small environmental pollutants : focusing on PAHs / Candace R. Spier, Michael A. Unger and Stephen L. Kaattari -- 16. Exoelectrogens-based electrochemical biosensor for environmental monitoring / Liu Deng, Li Shang and Shaojun Dong -- 17. Detecting waterborne parasites using piezoelectric cantilever biosensors / Sen Xu and Raj Mutharasan -- 18. Bioluminescence-based biosensor for food contamination / Jinping Luo. [et al.].
Record Nr. UNINA-9910826822003321
Boca Raton, Fla. : , : CRC Press, , 2012
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui