Free radicals, nitric oxide, and inflammation : molecular, biochemical, and clinical aspects / / edited by Aldo Tomasi, Tomris Ozben, and Vladimir P. Skulachev

• Pubblicazione: Amsterdam ; ; Washington, DC, : IOS Press, c2003
• Edizione: 1st ed.
• Descrizione fisica: 1 online resource (vii, 255 pages) : illustrations
• Disciplina: 616.0473
• Soggetto topico: Inflammation - Pathophysiology; Free radicals (Chemistry) - Pathophysiology; Nitric oxide - Pathophysiology
• Altri autori: TomasiAldo OzbenTomris SkulachevV. P (Vladimir Petrovich)
• Note generali: "Published in cooperation with NATO Scientific Affairs Division."; "Proceedings of the NATO Advanced Study Institute on Free Radicals, Nitric Oxide, and Inflammation: Molecular, Biochemical, and Clinical Aspects, 23 September-4 October 2001, Antalya, Turkey"--T.p. verso.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: ""Cover""; ""Title page""; ""Foreword""; ""Contents""; ""Alternative Functions of Mitochondria""; ""The Enzymatic Systems in the Regulation of Free Radical Lipid Peroxidation""; ""Flavanols and Procyanidins as Modulators of Oxidation in vitro and in vivo""; ""Estimation of Oxidative and Lipids Peroxidation DNA Adduct in Urine and DNA. Methodological Aspects and Application in Molecular Epidemiology""; ""Oxidative and Nitrosative Stress Mediated by Cyclosporine A in Endothelial Cells""; ""Early Signaling with Iron and Copper in Ischemic Preconditioning of the Heart"" ; ""Multiple Mechanisms Regulating Endothelial Nitric Oxide Synthase"" ""Nitric Oxide. Its Generation, Reactions and Role in Physiology""; ""Redox-Regulated Glutathionylation of Transcription Factors: A Regulatory Mode for Gene Expression""; ""Sulphur-Containing Amino Acids, Glutathione and the Modulation of Inflammation""; ""Molecular Events of the Inflammation Process that are Affected by α-Tocopherol. Antioxidants and Gene Expression in the Process of Inflammation and Wound Repair""; ""Redox Regulation, Cytokine, and Nitric Oxide in Inflammation"" ; ""Non-Traditional Cardiovascular Disease Risk Factors and Arterial Inflammatory Response in End-Stage Renal Disease"" ""Significance of Reactive Oxygen Species for Neuronal Function""; ""Protein Aggregates and the Development of Neurodegenerative Diseases""; ""Inflammatory Response of the Brain Following Cerebral Ischemia""; ""Carnosine as Natural Antioxidant and Neuroprotector: Biological Functions and Possible Clinical Use""; ""Atherosclerosis as a Free Radical Pathology and Antioxidative Therapy of this Disease"" ; ""H[sub(2)]O[sub(2)] Sensors of Lungs and Blood Vessels and their Role in the Antioxidant Defense of the Body"" ""Oxidative Lung Injury""; ""Proper Design of Human Intervention Studies, Power Calculations""; ""Author Index""
• Sommario/riassunto: Inflammation is the local response of a complex organism to an injury that serves as a mechanism initiating the elimination of noxious agents and of damaged tissues. Free radicals, and the very special free radical nitric oxide, are playing a relevant role in the pathogenesis of inflammation. This work introduces the general knowledge necessary to understand the inflammatory process and the role played by free radical and oxidative stress. The interplay between inflammatory molecules and cell signalling is also dealt with in depth.
• Titolo autorizzato: Free radicals, nitric oxide, and inflammation
• ISBN: 1-60129-427-1; 1-280-50545-1; 600-00-0431-1; 9786610505456
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910828434103321
• Lo trovi qui: Univ. Federico II
• Serie: NATO science series. : Series I, . -Life and behavioural sciences ; ; v. 346.