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Plant chemical biology / / edited by Dominique Audenaert, Paul Overvoorde
| Plant chemical biology / / edited by Dominique Audenaert, Paul Overvoorde |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : Wiley, , [2014] |
| Descrizione fisica | 1 online resource (321 p.) |
| Disciplina | 572/.2 |
| Altri autori (Persone) |
AudenaertDominique <1976->
OvervoordePaul <1968-> |
| Soggetto topico |
Botanical chemistry
Plants - Effect of chemicals on |
| ISBN |
1-118-74274-5
1-118-74292-3 1-118-74317-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Plant Chemical Biology; Copyright; Contents; Preface; Contributors; Part One Introduction; 1.1 From Herbal Remedies to Cutting-Edge Science: A Historical Perspective of Plant Chemical Biology; 1.1.1 Herbal Remedies and Pharmacology in the Ancient World; 1.1.2 Alchemy, Chemistry, and the Isolation of the Bioactive Metabolites; 1.1.3 The Discovery of Phytohormones and the Foundation of Modern Plant Chemical Biology; 1.1.4 The Dawn of Plant Synthetic Chemistry; 1.1.5 Serendipity Versus Rational Design of Chemical Libraries; 1.1.6 The Development of Combinatorial Chemistry
1.1.7 Plant Chemical Biology in the -Omics Era1.1.8 Introduction of Bioinformatics and Cheminformatics; 1.1.9 Unique Challenges in the Field of Chemical Genomic Research; 1.1.10 Concluding Remarks; Acknowledgments; References; Part Two Sources of Small Molecules; 2.1 Compound Collections; 2.1.1 Introduction; 2.1.2 Commercial Sources; 2.1.3 Companies Providing Nonproprietary, Nonparallel Synthesized Libraries Sourced Externally to the Company; 2.1.4 Companies Providing In-House Designed, Parallel Synthesized Libraries; 2.1.5 Results of Database Analysis 2.1.6 Compound Selection and Database Filtering2.1.7 Substructure Similarity/Dissimilarity; 2.1.8 Cluster Analysis; 2.1.9 Pharmacophore Analysis; 2.1.10 Compound Acquisition Format and Storage; Acknowledgments; References; 2.2 Combinatorial Chemistry Library Design; 2.2.1 Introduction; 2.2.2 Bioavailability; 2.2.3 Chemical Space; 2.2.4 Privileged Structures; 2.2.5 Fragment-Based Design; 2.2.6 Ligand-Based Design; 2.2.7 Structure-Based Design; 2.2.8 Conclusion and Summary; References; 2.3 Natural Product-Based Libraries; 2.3.1 Introduction; 2.3.2 Plant-Based Collections 2.3.3 Microbial-Derived Samples2.3.4 Samples of Marine Origin; 2.3.5 Future Perspectives; 2.3.6 Concluding Remarks; References; Part Three Identification of New Chemical Tools by High-Throughput Screening; 3.1 Assay Design for High-Throughput Screening; 3.1.1 Introduction; 3.1.2 Approaching Assay Development; 3.1.3 Assay Development; 3.1.4 Assay Types and Considerations; 3.1.5 Automation Adaptation and Validation; 3.1.6 Closing; Acknowledgment; References; Part Four Use of Chemical Biology to study Plant Physiology 4.1 Use of Chemical Biology to Understand Auxin Metabolism, Signaling, and Polar Transport4.1.1 Introduction; 4.1.2 Naturally Occurring Auxins; 4.1.3 Auxin Biosynthesis; 4.1.4 Auxin Conjugation and Release by Hydrolysis; 4.1.5 Synthetic Auxins; 4.1.6 Polar Auxin Transport; 4.1.7 Current Models of Auxin Signaling; 4.1.8 Application of Auxin-Related Molecules in Chemical Genetic Approach; 4.1.9 Chemical Probes on Auxin Signaling from Chemical Library and Natural Sources; 4.1.10 Rational Design of Auxin Antagonist on the Basis of TIR1 Structure 4.1.11 Chemical Probes on Auxin Transport from Chemical Library and Natural Sources |
| Record Nr. | UNINA-9910139031003321 |
| Hoboken, New Jersey : , : Wiley, , [2014] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Plant chemical biology / / edited by Dominique Audenaert, Paul Overvoorde
| Plant chemical biology / / edited by Dominique Audenaert, Paul Overvoorde |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : Wiley, , [2014] |
| Descrizione fisica | 1 online resource (321 p.) |
| Disciplina | 572/.2 |
| Altri autori (Persone) |
AudenaertDominique <1976->
OvervoordePaul <1968-> |
| Soggetto topico |
Botanical chemistry
Plants - Effect of chemicals on |
| ISBN |
1-118-74274-5
1-118-74292-3 1-118-74317-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Plant Chemical Biology; Copyright; Contents; Preface; Contributors; Part One Introduction; 1.1 From Herbal Remedies to Cutting-Edge Science: A Historical Perspective of Plant Chemical Biology; 1.1.1 Herbal Remedies and Pharmacology in the Ancient World; 1.1.2 Alchemy, Chemistry, and the Isolation of the Bioactive Metabolites; 1.1.3 The Discovery of Phytohormones and the Foundation of Modern Plant Chemical Biology; 1.1.4 The Dawn of Plant Synthetic Chemistry; 1.1.5 Serendipity Versus Rational Design of Chemical Libraries; 1.1.6 The Development of Combinatorial Chemistry
1.1.7 Plant Chemical Biology in the -Omics Era1.1.8 Introduction of Bioinformatics and Cheminformatics; 1.1.9 Unique Challenges in the Field of Chemical Genomic Research; 1.1.10 Concluding Remarks; Acknowledgments; References; Part Two Sources of Small Molecules; 2.1 Compound Collections; 2.1.1 Introduction; 2.1.2 Commercial Sources; 2.1.3 Companies Providing Nonproprietary, Nonparallel Synthesized Libraries Sourced Externally to the Company; 2.1.4 Companies Providing In-House Designed, Parallel Synthesized Libraries; 2.1.5 Results of Database Analysis 2.1.6 Compound Selection and Database Filtering2.1.7 Substructure Similarity/Dissimilarity; 2.1.8 Cluster Analysis; 2.1.9 Pharmacophore Analysis; 2.1.10 Compound Acquisition Format and Storage; Acknowledgments; References; 2.2 Combinatorial Chemistry Library Design; 2.2.1 Introduction; 2.2.2 Bioavailability; 2.2.3 Chemical Space; 2.2.4 Privileged Structures; 2.2.5 Fragment-Based Design; 2.2.6 Ligand-Based Design; 2.2.7 Structure-Based Design; 2.2.8 Conclusion and Summary; References; 2.3 Natural Product-Based Libraries; 2.3.1 Introduction; 2.3.2 Plant-Based Collections 2.3.3 Microbial-Derived Samples2.3.4 Samples of Marine Origin; 2.3.5 Future Perspectives; 2.3.6 Concluding Remarks; References; Part Three Identification of New Chemical Tools by High-Throughput Screening; 3.1 Assay Design for High-Throughput Screening; 3.1.1 Introduction; 3.1.2 Approaching Assay Development; 3.1.3 Assay Development; 3.1.4 Assay Types and Considerations; 3.1.5 Automation Adaptation and Validation; 3.1.6 Closing; Acknowledgment; References; Part Four Use of Chemical Biology to study Plant Physiology 4.1 Use of Chemical Biology to Understand Auxin Metabolism, Signaling, and Polar Transport4.1.1 Introduction; 4.1.2 Naturally Occurring Auxins; 4.1.3 Auxin Biosynthesis; 4.1.4 Auxin Conjugation and Release by Hydrolysis; 4.1.5 Synthetic Auxins; 4.1.6 Polar Auxin Transport; 4.1.7 Current Models of Auxin Signaling; 4.1.8 Application of Auxin-Related Molecules in Chemical Genetic Approach; 4.1.9 Chemical Probes on Auxin Signaling from Chemical Library and Natural Sources; 4.1.10 Rational Design of Auxin Antagonist on the Basis of TIR1 Structure 4.1.11 Chemical Probes on Auxin Transport from Chemical Library and Natural Sources |
| Record Nr. | UNINA-9910820309903321 |
| Hoboken, New Jersey : , : Wiley, , [2014] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||