Pubbl/distr/stampa |
London : , : Elsevier Science, , 2014
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Descrizione fisica |
1 online resource (1050 p.)
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Disciplina |
617.954
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Altri autori (Persone) |
OrlandoGiuseppe
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Soggetto topico |
Regenerative medicine
Tissue engineering
Transplantation of organs, tissues, etc
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Soggetto genere / forma |
Electronic books.
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ISBN |
0-12-398520-X
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Formato |
Materiale a stampa ![](img/format/mas.png) |
Livello bibliografico |
Monografia |
Lingua di pubblicazione |
eng
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Nota di contenuto |
Front Cover; Regenerative Medicine Applications in Organ Transplantation; Copyright Page; Dedication; Contents; Meet the Editors; List of Contributors; Preface; 1 Introduction: Regenerative Medicine and Solid Organ Transplantation from a Historical Perspective; 1.1 Introduction; 1.2 Major Advances in Organ Transplantation; 1.2.1 Vascular Reconstruction; 1.2.2 Organ Preservation; 1.2.3 Artificial Support; 1.2.4 Immunosuppression; 1.2.5 Operational Tolerance; 1.2.6 Organ Recovery and Definition of Brain Death; 1.2.7 Living Donation; 1.2.8 HLA Typing and Crossmatch; 1.3 Regenerative Medicine
1.3.1 A New Term in Transplantation: Regenerative Medicine1.3.2 Characteristics of Regenerative Tissues; 1.3.3 Polymer Development; 1.3.4 Early Tissue Development; 1.3.5 Cell Source; 1.3.6 Soft Tissue Regeneration as Applied to Battlefield Medicine; 1.3.7 Planar Acellular Dermal Matrices; 1.3.8 Vascularization of Tissue-Engineered Organs; 1.3.9 Perfusion Decellularization, Using Nature's Vascular Network; 1.3.10 Specific Organ Transplantation History and Link to Engineering; 1.3.10.1 Liver; 1.3.10.2 Kidney; 1.3.10.3 Heart; 1.3.10.4 Lung; 1.3.10.5 Pancreas; 1.3.10.6 Intestine
1.3.11 Concluding RemarksReferences; 2 Solid Organ Transplantation: Has the Promise Been Kept and the Needs Met?; 2.1 Introduction; 2.2 Tolerance in organ transplantation; 2.2.1 Tolerogenic Approaches; 2.2.1.1 T-Cell Depletion; 2.2.1.2 Costimulation Blockade; 2.2.1.3 B-Cell Therapies; 2.2.1.4 Chimerism; 2.2.1.5 Regulatory T Cells; 2.2.1.6 Maintenance IS; 2.2.2 Spontaneous Operational Tolerance; 2.2.3 Biomarkers of Operationally Tolerant Transplant Recipients; 2.3 Organ shortage; 2.3.1 Strategies to Increase the Donor Pool; 2.3.1.1 Increasing the Donation Rates
2.3.1.2 Greater Use of Deceased Potential Donors2.3.1.3 Splitting Livers; 2.3.1.4 Living Donation; 2.3.1.5 Improved Use of Organs; 2.3.1.6 Xenotransplantation; 2.4 Conclusions; Abbreviations; References; I: Principles of Regenerative Medicine and Cell, Tissue, and Organ Bioengineering; 3 Strategies for the Specification of Tissue Engineering Biomaterials; 3.1 Introduction: the Engineering Approach to Tissue Regeneration; 3.2 Principles of Biomaterials Selection in Tissue Engineering; 3.2.1 The Concept of Tissue Engineering Templates; 3.2.2 The Objectives of Tissue Engineering Templates
3.2.3 Classification of Tissue Engineering Templates3.2.4 Specifications for Template Materials; 3.2.4.1 Mandatory Specifications; 3.2.4.2 Optional/Application-Specific Requirements; 3.3 Specific Types of Template Material; 3.3.1 Porous Solids; 3.3.2 Hydrogels; 3.3.3 ECM-Derived Materials; 3.4 Concluding Comments; Author's Note; References; 4 Principles of Stem Cell Biology; 4.1 The Origin of the Cell Reprogramming; 4.2 Somatic Cell Nuclear Transfer; 4.2.1 SCNT in Amphibians; 4.2.2 SCNT in Mammals; 4.3 Cell Fusion; 4.3.1 The Transcription Factors Induce Cell Lineage Switch
4.4 Transcription Factor Transduction: iPS Cell Generation
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Record Nr. | UNINA-9910453586003321 |