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Biomaterials- and Microfluidics-Based Tissue Engineered 3D Models / / edited by J. Miguel Oliveira, Rui L. Reis
| Biomaterials- and Microfluidics-Based Tissue Engineered 3D Models / / edited by J. Miguel Oliveira, Rui L. Reis |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
| Descrizione fisica | 1 online resource (VII, 175 p. 42 illus., 40 illus. in color.) |
| Disciplina | 610.28 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Medicine
Regenerative medicine Tissue engineering Biomedical engineering Biomedical materials Biomedicine, general Regenerative Medicine/Tissue Engineering Biomedical Engineering and Bioengineering Biomaterials Enginyeria biomèdica Materials biomèdics Medicina regenerativa Teixit connectiu |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-36588-3 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Microfluidic devices and three dimensional-printing strategies for in vitro models of bone -- Microfluidics for Processing of biomaterials -- Organ-on-a-chip -- Body-on-a-chip: Current challenges -- Biomaterials and microfluidics for liver models -- Microfluidics for CNS research -- Biomaterials and microfluidics for angiogenesis research -- Biomaterials and microfluidics for drug discovery and development -- Microfluidics for diagnostics -- Nanoparticles and Microfluidic devices in cancer research. |
| Record Nr. | UNINA-9910409699603321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Handbook of the Extracellular Matrix : Biologically-Derived Materials
| Handbook of the Extracellular Matrix : Biologically-Derived Materials |
| Autore | Maia F. Raquel |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing AG, , 2024 |
| Descrizione fisica | 1 online resource (1322 pages) |
| Altri autori (Persone) |
OliveiraJ. Miguel
ReisRui L |
| ISBN |
9783031563638
9783031563621 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Contents -- About the Editors -- Contributors -- Part I: Fundamentals of the Extracellular Matrix -- 1 Composition of the Extracellular Matrix -- Introduction -- Collagens, the Most Abundant Structural Components of the Extracellular Matrix -- Collagen Genes and Collagen Chains -- The Collagen Domain -- Fibril-Forming Cogens Collagens -- Non-fibrillar Collagens -- Network-Forming Collagens IV, VI, VIII, and X -- A Collagen Unique of Its Kind, Collagen VII -- FACITs -- Transmembrane Collagens -- Multiplexins -- Glycoproteins of the Extracellular Matrix -- Fibronectin -- Laminins and Related Glycoproteins -- Elastin and Elastic Fibers -- Elastin -- Fibrillins and LTBPs -- Fibulins -- Non-structural Glycoproteins -- Tenascins -- Thrombospondins -- SPARC/BM-40/Osteonectin and the SPOCK/Testican Family -- Glycosaminoglycans and Proteoglycans -- Extracellular Proteoglycans -- The Small Leucine-Rich Proteoglycans (SLRPs) -- Hyalectans/Lecticans -- Basement Membrane Proteoglycans Perlecan and Agrin -- Cell Surface Proteoglycans -- Syndecans -- Glypicans -- Other Transmembrane Proteoglycans -- Supramolecular Assemblies -- The Network of Fibril-Forming Collagens -- The Classical Supramolecular Structure of Basement Membranes -- A Supramolecular Structure Specific to Basement Membrane Underlying Stratified Epithelia -- Conclusions and Perspectives -- References -- 2 Extracellular Matrix Bioscaffolds: Structure-Function -- Introduction -- ECM Genesis -- Composition and Structure of the ECM -- ECM Function and Structure -- ECM Bioscaffolds for Tissue Repair -- Clinical Applications of Bioscaffolds -- Future Perspectives -- Conclusion -- References -- 3 Extracellular Matrix Bioactive Molecules and Cell Behavior Modeling -- Introduction -- Extracellular Matrix (ECM) Components -- The ECM as a Reservoir for Bioactive Molecules.
Growth Factors -- Heparin for Growth Factor Release -- Biomimetic ECMs -- Engineered ECMs with Bioactive Motifs -- RGD -- IKVAV -- YIGSR -- Design Considerations of Peptide Motifs -- Comparison of Motifs in Modulating Cellular Behavior -- Challenges and Future Directions -- Cross-References -- References -- 4 Mechanical Properties of the Extracellular Matrix -- Introduction -- Mechanics of the Different ECM Components -- Collagens -- Elastin -- Fibronectin -- Proteoglycans and Glycosaminoglycans -- Models to Study the Mechanical Properties of the ECM -- Endogenous ECM -- Decellularization of Tissues -- ECM Hydrogels -- Measurement of the ECM Mechanics -- Tensile and Compression Testing -- Rheological Characterization -- Atomic Force Microscopy -- Cell-ECM Mechanical Interactions Measurement -- Future Directions -- References -- 5 Collagen Fibril Reinforcement in Connective Tissue Extracellular Matrices -- Introduction -- Collagen Fibril Reinforcing ECM: How It All Began -- The Holmes-Chapman-Kadler Discovery: Seeing Is Believing -- Collagen Fibril Reinforcing ECM Hypothesis: Much Ado About Theories? -- Stress Transfer Mechanism in ECM -- A Framework for ECM Mechanics -- Elastic Stress Transfer in ECM: A General Theory at Last -- The Topçu Model -- Fibril Ends -- Interfacial Interactions -- The Shear-Lag (Beta) Parameter -- Three-Dimensional Unit Cell -- Application to Fibers with Tapered (Paraboloidal) Ends -- Influence of Elastic Moduli Ratio and Fibril Slenderness on Axial Stress Uptake -- Critical Length for Fibril Yielding -- Conclusion -- References -- 6 Extracellular Matrix Isolation: Sources and Methods -- Introduction -- ECM Isolation Methods -- Chemical Methods -- Enzymatic Methods -- Physical Methods -- Sources: ECM from Healthy Tissues -- Tissues Derived from the Mesoderm -- Bone -- Cartilage -- Adipose Tissue -- Muscle. Cardiovascular Tissue -- Vascular Tissue -- Dermal Tissue -- Kidney -- Tissues Derived from the Endoderm -- Respiratory System -- Pancreas -- Liver -- Digestive Tract -- Tissues Derived from the Ectoderm -- Nervous System -- Cornea -- Sources: ECM from Tumors -- Mammary Gland Tumors -- Colon Tumors -- Liver Tumors -- Brain Tumors -- Sources: ECM from in Vitro Cultured Cells -- Clinical Applications of Decellularized ECM -- Conclusions -- References -- 7 Strategies for Mimicking Extracellular Matrix -- Introduction -- Mimicking the Biochemical Properties of ECMs -- Collagens -- Polysaccharides -- Fibrin -- Elastin -- Fibronectin -- ECM Blents -- Mimicking the Mechanical Properties -- Soft Tissues -- Elastic Tissues -- Hard Tissues -- Mimicking the Topography -- Examples of Strategies to Mimic ECMs -- Design of Cardiac or Skeletal Muscle ECM to Develop 3D In Vitro Models -- Mimicking Intervertebral Disk Structure and Physical Properties to Treat Disk Degeneration -- Nucleus Pulposus -- Annulus Fibrosus -- Mimicking Topography and Biochemical Properties of Compact Bone -- Future Directions -- Concluding Remarks -- Cross-References -- References -- 8 Extracellular Matrix Remodeling on Cancer Progression -- Introduction -- The Two Compartments of ECM -- Basement Membrane -- Major Components of BM and Their Function -- Interstitial Matrix -- Major Components of IM and Their Function -- Remodeling of ECM in Tumorigenesis -- Tumorigenic ECM Remodeling Mechanisms -- ECM Deposition and Modification -- Posttranslational Modification -- ECM Degradation -- Force-Mediated ECM Remodeling -- ECM Remodeling in Primary Tumor -- ECM Remodeling During Tumor Cell Migration -- Vital Extracellular Matrix Components and Their Role in Remodeling -- Collagen -- Matrix Metalloproteinases -- Lysyl Oxidase -- TGF-β -- Conclusion -- References -- Part II: Protein-Based Materials. 9 Advances in ECM Protein-Based Materials -- Introduction -- ECM Protein Categories -- Fibrous Proteins -- Collagen -- Elastin -- Glycoproteins -- Proteoglycans -- Fibronectin -- Laminin -- Protein-Based Materials -- 0D Structure -- 1D Structure -- 2D Structure -- 3D Structure -- ECM Protein-Based Structures -- Collagen -- 1D Collagen-Based Structures -- 2D Collagen-Based Structures -- 3D Collagen-Based Structures -- Elastin -- 1D Elastin-Based Structures -- 2D Elastin-Based Structures -- 3D Elastin-Based Structures -- Proteoglycans -- 1D Proteoglycan-Based Structures -- 2D Proteoglycan-Based Structures -- 3D Proteoglycan-Based Structures -- Fibronectin -- 1D Fibronectin-Based Structures -- 2D Fibronectin-Based Structures -- 3D Fibronectin-Based Structures -- Laminin -- 1D Laminin-Based Structures -- 2D Laminin-Based Structures -- 3D Laminin-Based Structures -- Conclusions and Outlook -- References -- 10 Protein-Based Scaffolds for Musculoskeletal Tissue Repair and Regeneration -- Introduction -- Key Musculoskeletal Tissues and Their Compositions -- Bone -- Cartilage -- Other Key Connective/Musculoskeletal Tissues -- Proteins in Musculoskeletal Tissue Engineering -- Key Proteins Biochemistry, Structure, and Application in Musculoskeletal Tissue Engineering -- Collagens -- Gelatin -- Silkworm Silk -- Fibrin and Elastin -- Protein-Based Scaffolds for Musculoskeletal Tissue Engineering -- Bone Tissue Engineering -- Cartilage Tissue Engineering -- Tendon and Ligament Tissue Engineering -- Cross-linking of Protein-Based Biomaterials -- Design and Fabrication of Protein-Based Scaffolds -- Commercially Available Protein-Based Biomaterials for Musculoskeletal Tissue Regeneration -- Perspective Summary -- Cross-References -- References -- 11 Protein-Based Materials as Cancer In Vitro Models -- Introduction -- Collagen as In Vitro Cancer Model. Collagen-Based Hydrogels -- Gelatin as In Vitro Cancer Model -- Gelatin-Based Hydrogels -- Fibrin as In Vitro Cancer Model -- Fibrin-Based Hydrogels -- Silk Fibroin as In Vitro Cancer Model -- Silk Fibroin-Based Hydrogels -- Conclusions and Future Perspectives -- Cross-References -- References -- 12 Proteins and Polypeptides as Biomaterials Inks for 3D Printing -- Introduction -- Protein-Based Biomaterials -- Engineered Proteins -- Crosslinking Methods and Chemical Modifications -- Physical and Noncovalent Crosslinking -- Chemical Crosslinking -- Photocrosslinking -- Chemical Reactions and Chemical Crosslinkers -- Enzymatic Crosslinking -- Commercially Available Protein-Based Biomaterials Inks -- Considerations for Using Protein-Based Biomaterials Inks -- Conclusion and Future Perspective -- Cross-References -- References -- 13 Protein-Based Microfluidic Models for Biomedical Applications -- Introduction -- Synthesis of Microfluidic Protein-Based Biomaterials -- Subtractive Approaches -- Additive Approaches -- Approaches That Use Biologically Derived Patterns -- Microfluidic ECMs in Models of the Microvascular System -- Transformation of Microfluidic Channels into Microvessels -- Physical Factors in Microfluidic Vascularization -- Models of Microvascular Activation -- Models of Microvascular Transport and Drainage -- Computational Design of Microfluidic ECM for Vascularization -- Microfluidic ECMs in Models of Epithelial Ducts -- Similarities and Differences with Endothelialization -- Formation of Epithelial Tubes in Microfluidic ECM -- Design Considerations for Epithelialization -- Conclusions -- Cross-References -- References -- 14 Protein-Based Materials in Cosmetics -- Introduction -- History of Use of Proteins in Cosmetics -- Skin Aging -- Hair Damages -- Definition of the Cosmetics-Related Proteins -- Native Proteins -- Protein Hydrolysates. Quat Proteins. |
| Record Nr. | UNINA-9910874670703321 |
Maia F. Raquel
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| Cham : , : Springer International Publishing AG, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Injuries and Health Problems in Football : What Everyone Should Know / / edited by C. Niek van Dijk, Philippe Neyret, Moises Cohen, Stefano Della Villa, Helder Pereira, J. Miguel Oliveira
| Injuries and Health Problems in Football : What Everyone Should Know / / edited by C. Niek van Dijk, Philippe Neyret, Moises Cohen, Stefano Della Villa, Helder Pereira, J. Miguel Oliveira |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (XIV, 703 p. 245 illus., 173 illus. in color.) |
| Disciplina | 617.47 |
| Soggetto topico |
Orthopedics
Traumatology Sports medicine Rehabilitation Surgical Orthopedics Traumatic Surgery Sports Medicine |
| ISBN | 3-662-53924-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Fundamental Principles. Football Traumatology: Ankle and Foot Injuries -- Knee Injuries -- Hip and Groin Injuries -- Spine and head injuries -- Upper Limb Injuries. Muscle, tendon and bone stress injuries: Muscle injuries in the lower limb -- Tendon injuries in the lower limb -- Bone stress injuries in the lower limb. Heart and health conditions. Follow-up, Rehabilitation and Return to activity. Performance enhancement -- “New” biologic treatments. |
| Record Nr. | UNINA-9910254654103321 |
| Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Osteochondral Tissue Engineering : Challenges, Current Strategies, and Technological Advances / / edited by J. Miguel Oliveira, Sandra Pina, Rui L. Reis, Julio San Roman
| Osteochondral Tissue Engineering : Challenges, Current Strategies, and Technological Advances / / edited by J. Miguel Oliveira, Sandra Pina, Rui L. Reis, Julio San Roman |
| Edizione | [1st ed. 2018.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
| Descrizione fisica | 1 online resource (IX, 511 p. 86 illus., 79 illus. in color.) |
| Disciplina |
612.028
571.538 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Regenerative medicine
Tissue engineering Biomedical engineering Biomaterials Regenerative Medicine/Tissue Engineering Biomedical Engineering/Biotechnology Biomedical Engineering and Bioengineering |
| ISBN | 3-319-76735-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part I: Current Challenges in Osteochondral Repair and Regeneration: Trauma vs Disease -- Advances for treatment of knee OC defects -- Emerging Concepts in Treating Cartilage, Osteochondral Defects and Osteoarthritis of the Knee and Ankle -- Osteoarthritis: Trauma Vs Disease -- Surgical Treatment Paradigms of Ankle Lateral Instability, Osteochondral Defects and Impingement -- Part II: Viscosupplementation -- Clinical management in early OA -- Hyaluronic Acid -- Semi-IPNs and IPNs Based Hydrogels -- Promising biomolecules -- Part III: Technological Advances in Osteochondral Tissue Engineering -- Nanoparticles-based systems for Osteochondral Tissue Engineering -- Stem cells for osteochondral regeneration -- PRP Therapy -- Enhancing biological and biomechanical fixation of osteochondral scaffold: a grand challenge -- Part IV: Osteochondral Tissue Engineering approaches -- Combination of polymeric supports and drug delivery systems for ostechondral regeneration -- Osteochondral Angiogenesis and Promoted Vascularization: New Therapeutic Target -- Models Of Disease -- Part V: In vitro models for Osteochondral Regeneration -- Tissue Engineering Strategies for Osteochondral Repair -- In vitro mimetic models for the bone-cartilage interface regeneration -- Bioreactors and microfluidics for osteochondral interface maturation -- Part VI: In vivo models for Osteochondral Regeneratio -- nSmall Animal Models -- Large animal models for Osteochondral Regeneration -- Index. |
| Record Nr. | UNINA-9910298426703321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Osteochondral Tissue Engineering : Nanotechnology, Scaffolding-Related Developments and Translation / / edited by J. Miguel Oliveira, Sandra Pina, Rui L. Reis, Julio San Roman
| Osteochondral Tissue Engineering : Nanotechnology, Scaffolding-Related Developments and Translation / / edited by J. Miguel Oliveira, Sandra Pina, Rui L. Reis, Julio San Roman |
| Edizione | [1st ed. 2018.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
| Descrizione fisica | 1 online resource (ix, 438 pages) : illustrations |
| Disciplina | 610.28 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Regenerative medicine
Tissue engineering Biomedical engineering Biomaterials Regenerative Medicine/Tissue Engineering Biomedical Engineering/Biotechnology Biomedical Engineering and Bioengineering |
| ISBN | 3-319-76711-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part I: Biomaterials advances in Osteochondral Tissue -- Natural Origin Materials for Osteochondral Tissue Engineering -- Synthetic Materials for Osteochondral Tissue Engineering -- Bioceramics for Osteochondral Tissue Engineering and Regeneration -- Part II: Nanotechnology approaches for Osteochondral Tissue Engineering -- Nanomaterials/nanocomposites for Osteochondral Tissue -- Nano- and Micro-Fibers for Osteochondral Tissue Engineering -- Micro/Nano Scaffolds for Osteochondral Tissue Engineering -- Part III: Osteochondral Tissue Scaffolding -- Mimetic Hierarchical Approaches for Osteochondral Tissue Engineering -- Porous scaffolds for regeneration of cartilage, bone and osteochondral tissue -- Layered Scaffolds for Osteochondral Tissue Engineering -- Part IV: Advanced Processing Methodology -- Preparation of polymeric and composite scaffolds by 3D Bioprinting -- The Use of Electrospinning Technique on OsteoChondral Tissue Engineering -- Supercritical Fluid Technology as a Tool to Prepare Gradient Multifunctional Architectures towards Regeneration of Osteochondral Injuries -- Part V: Hydrogels Systems for Osteochondral Tissue Applications -- Gellan Gum-based Hydrogels for Osteochondral Repair -- Silk Fibroin-Based Hydrogels and Scaffolds for Osteochondral Repair and Regeneration -- In Situ Crosslinkable Polymer Systems and Composites for Osteochondral Regeneration -- Part VI: Translation of Osteochondral Tissue Products -- Stem Cells in Osteochondral Tissue Engineering -- Osteochondral Tissue Engineering: Translational Research and Turning Research into Products -- Clinical trials and Management of Osteochondral Lesions -- Commercial Products for Osteochondral Tissue Repair and Regeneration -- Index. |
| Record Nr. | UNINA-9910298427303321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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