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Pediatric Nephrology / / edited by Ellis D. Avner, William E. Harmon, Patrick Niaudet, Norishige Yoshikawa, Francesco Emma, Stuart L. Goldstein
| Pediatric Nephrology / / edited by Ellis D. Avner, William E. Harmon, Patrick Niaudet, Norishige Yoshikawa, Francesco Emma, Stuart L. Goldstein |
| Edizione | [7th ed. 2016.] |
| Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (503 illus., 250 illus. in color. eReference.) |
| Disciplina | 618.9261 |
| Soggetto topico |
Nephrology
Pediatrics Urology Internal medicine Family medicine Internal Medicine General Practice / Family Medicine |
| ISBN | 3-662-43596-9 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Embryology -- Glomerular Circulation and Function -- Renal Tubular Development -- Perinatal Urology Renal Dysplasia/Hypoplasia -- Syndromes and Malformations of the Urinary Tract -- Sodium and Water: Developmental Physiology and Basic Disorders -- Potassium: Developmental Physiology and Basic Disorders -- Acid-Base Homeostasis: Developmental Physiology and Basic Disorders -- Calcium and Phosphorus: Developmental Physiology -- Disorders of Calcium and Phosphate and Therapy Nutrition: Developmental Physiology and Basic Disorders -- Fluid and Electrolyte Maintenance and Therapy of Basic Disorders (Na/HO/K/Acid Base) -- Molecular Biology -- Animal Models -- Clinical Investigation -- Genomic Methods in the Diagnosis and Treatment of Pediatric Kidney Disease -- Renal Stem Cells -- Tissue Engineering -- Clinical Evaluation -- Laboratory Investigation -- Growth and Development -- Diagnostic Imaging -- Renal Pathology -- Congenital Nephrotic Syndrome -- Inherited Glomerular Diseases -- Idiopathic Nephrotic Syndrome: Genetic Aspects -- Idiopathic Nephrotic Syndrome: Clinical Aspects -- Immune Mediated Glomerular Injury -- Complement Mediated Glomerular Injury -- Acute Postinfectious Glomerulonephritis -- Immunoglobulin A Nephropathies (includes HSP) -- Membranoproliferative and C3-Mediated GN -- Membranous Nephropathy -- Nephronophthisis-Medullary Cystic Kidney Disease -- Polycystic Kidney Disease -- Animoaciduria and Glycosuria -- Tubular Disorders of Electrolyte Regulation -- Renal Tubular Acidosis -- Nephrogenic Diabetes Insipidus -- Cystinosis -- Fanconi Syndrome -- Primary Hyperoaxaluria -- Tubulointerstitial Nephritis -- Vasculitis -- Systemic Lupus Erythematosis -- HUS -- Sickle Cell Nephropathy -- Diabetic Nephropathy -- Renal Manifestations of Metabolic Disorders -- Infectious Diseases and the Kidney Nephrotoxins -- Urinary Tract Infections -- Vesicoureteral Reflux and Scarring -- Obstructive Uropathy -- Bladder Dysfunction -- Urolithiasis -- Pediatric Renal Tumors -- Epidemiology of Hypertension -- Pathophysiology of Hypertension -- Evaluation of Hypertension in Childhood Diseases -- Management of the Hypertensive Child -- Pathogenesis of Acute Renal Failure -- Evaluation and Management of Acute Kidney Injury -- Pathophysiology of Progressive Renal Disease -- Management of Chronic Kidney Disease -- Handling of Drugs in Children with Abnormal Renal Function -- Endocrine and Growth Abnormalities -- Chronic Kidney Disease Mineral and Bone Disorder -- Peritoneal Dialysis -- Hemodialysis -- Transplantation Immunology -- Pediatric Renal Transplantation -- Immunosuppression -- Complications of Renal Transplantation -- IPNA: Global Pediatric Nephrology, Introduction and Overview -- AFPNA -- ALANEPE -- AsPNA -- ASPN -- ANZPNA -- ESPN -- JSPN. |
| Record Nr. | UNINA-9910254504303321 |
| Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pediatric Nephrology [[electronic resource] /] / edited by Ellis D. Avner, William E. Harmon, Patrick Niaudet, Norishige Yoshikawa
| Pediatric Nephrology [[electronic resource] /] / edited by Ellis D. Avner, William E. Harmon, Patrick Niaudet, Norishige Yoshikawa |
| Edizione | [6th ed. 2009.] |
| Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2009 |
| Descrizione fisica | 1 online resource (eReference.) |
| Disciplina | 618.9261 |
| Soggetto topico |
Nephrology
Pediatrics Urology Internal medicine General practice (Medicine) Internal Medicine General Practice / Family Medicine |
| ISBN |
1-280-38450-6
9786613562425 3-540-76341-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Table of Contents -- Embryology -- Introduction -- Anatomy of Kidney Development -- Overview -- Pronephros and Mesonephros -- Metanephros -- The Ureter and Urinary Bladder -- Methods Used to Study the Biology of Nephrogenesis -- Descriptive Studies of Gene Expression -- Functional Studies In Vitro -- Functional Studies In Vivo -- Cell Biology of Nephrogenesis -- Cell Proliferation and Cell Death -- Differentiation -- Morphogenesis -- Molecular Control of Nephrogenesis -- Overview -- Transcription Factors -- Growth Factors -- Adhesion Molecules -- Conversion of Metanephric Mesenchyme into Nephron Epithelia -- Uninduced Metanephric Mesenchyme Is Preprogrammed to Form Nephrons -- Uninduced Metanephric Mesenchyme Is Preprogrammed to Die -- Condensation of Renal Mesenchyme -- Morphogenesis into Nephron Tubules -- Formation of the Glomerulus -- Branching Morphogenesis of the Ureteric Bud -- Growth Factor Control of Ureteric Bud Growth -- Transcription Factors and Ureteric Bud Growth -- Cell Adhesion Molecules and Ureteric Bud Growth -- Further Maturation of the Collecting Ducts -- Metanephric Stromal Cells -- Lower Urinary Tract Development -- References -- Glomerular Circulation and Function -- Renal Blood Flow -- Development of Renal Blood Flow -- Prenatal Renal Blood Flow -- Postnatal Renal Blood Flow -- Measurement of Renal Blood Flow -- Indirect Assessment of Renal Blood Flow -- Glomerular Filtration -- Theoretical Considerations of Glomerular Filtration -- Effect of Perturbation in the Determinants of SNGFR -- Mean Glomerular Transcapillary Hydraulic Pressure Difference, deltaP -- Systemic Plasma Colloid Osmotic Pressure, piA -- Glomerular Plasma Flow Rate, QA -- Glomerular Capillary Ultrafiltration Coefficient, Kf -- Defense of Glomerular Filtration Rate -- Myogenic Reflex -- Tubuloglomerular Feedback (TGF).
Development of Glomerular Filtration Rate -- Ontogenic Development of Glomerular Capillaries -- Prenatal GFR -- Postnatal GFR -- Impaired Fetal Glomerular Development and Adult Disease -- Low Birth Weight -- Extreme Prematurity -- Maternal Factors -- Clinical Assessment of Glomerular Filtration Rate -- Inulin Clearance -- Modifications of the Standard Clearance Method -- Creatinine as a Marker of GFR -- Cystatin C as a Marker of GFR -- Other Endogenous Markers of GFR -- Glomerular Sieving of Macromolecules -- Role of Endothelial Cells -- Role of Glomerular Basement Membrane -- Role of Podocytes -- Role of the Renin Angiotensin System -- References -- Renal Tubular Development -- Organization of the Nephron -- Principals of Membrane Transport -- Maturation of Na+-K+-ATPase along the Nephron -- Proximal Tubule Transport -- Glucose Transport -- Amino Acid Transport -- Organic Acid Transport -- Phosphate Transport -- Proximal Tubule Acidification -- Proximal Tubule NaCl Transport -- Proximal Tubule Water Transport -- Thick Ascending Limb -- Distal Convoluted Tubule -- Urinary Concentration and Dilution -- Distal Tubule Acidification -- Cortical Collecting Tubule Sodium Transport -- Potassium Transport -- References -- Perinatal Urology -- Diagnosis -- Diagnostic Accuracy -- Ureteropelvic Junction Obstruction -- Cystic Kidneys -- Ureterovesical Junction Obstruction -- Duplication Anomalies -- Vesicoureteral Reflux -- Posterior Urethral Valves -- Rationale for Prenatal Intervention -- Clinical Experience with Intervention for Prenatal Hydronephrosis -- Postnatal Management of Infants with Prenatally Diagnosed Urologic Renal Abnormality -- Unilateral Hydronephrosis -- Bilateral Hydronephrosis -- Renal Agenesis, Renal Ectopia and Unilateral Multicystic Dysplastic Kidney -- Summary -- Acknowledgment -- References -- Renal Dysplasia/Hypoplasia -- Introduction. Renal Agenesis -- Bilateral Renal Agenesis (BRA) -- Unilateral Renal Agenesis (URA) -- Multicystic/Dysplastic Kidney (MCDK) -- Abnormalities of Kidney Position and Patterning -- Primary Renal Hypoplasia -- Renal Coloboma Syndrome -- Branchio-Oto-Renal Syndrome -- Renal Tubular Dysgenesis (RTD) -- Renal Dysplasia/Hypoplasia and Vesico-Ureteral Reflux -- Renal Hypoplasia/Dysplasia and Fetal Urinary Tract Obstruction -- Syndromic Renal Hypoplasia/Dysplasia -- Genetic and Environmental Causes of Subtle Renal Hypoplasia -- References -- Syndromes and Malformations of the Urinary Tract -- Introduction -- Prevalence of Urinary Tract Anomalies -- Approach to the Child with a Urinary Tract Anomaly -- Overview of Normal Embryogenesis of the Urinary System -- Anomalies Involving the Urinary Tract -- Kidney Defects -- Renal Agenesis -- Ectopic Kidney -- Horseshoe Kidney -- Dysplasia and Polycystic Kidney -- Obstruction and Hydronephrosis -- Ureter Defects -- Duplication -- Hydroureter -- Bladder Defects -- Bladder Exstrophy -- Urethral Defects -- Agenesis and Atresia -- Duplication -- Posterior Urethral Valves -- Associations and Sequences Involving the Urinary Tract -- VATER Association -- CHARGE Syndrome (CHARGE Association) -- MURCS Association -- Oligohydramnios Sequence -- Urethral Obstruction Sequence -- Sirenomelia Sequence -- References -- Sodium and Water -- Introduction -- Body Fluid Compartments and their Composition -- Total Body Water and its Compartments -- Composition of Body Water Compartments -- Maintenance Sodium and Water Requirements -- Sodium -- Water -- Distinct Roles of Sodium and Water in Body Fluid Homeostasis -- Sensor Mechanisms: Sodium and Water -- Sodium -- Atrial Receptors -- Hepatic Receptors -- Pulmonary Receptors -- Carotid Arch Receptors -- Cerebral Receptors -- Water -- AVP -- Efferent Mechanisms: Sodium and Water -- Sodium. Renin-Angiotensin-Aldosterone Axis -- Endothelin -- Renal Nerves -- Atrial Natriuretic Peptide -- Prostaglandins -- Kinins -- Nitric Oxide -- Adrenomedullin -- Water -- AVP -- Angiotensin -- Thirst -- Effector Mechanisms: Sodium and Water -- Sodium -- GFR -- Proximal Tubule -- Distal Nephron Including Collecting Duct -- Water -- AVP -- Countercurrent Mechanism -- Osmoprotective Molecule (Compatible Osmolytes) -- Laboratory Assessment of Sodium and Water Balance -- Sodium -- Water -- Overview of the Evaluation of Fluid and Water Abnormalities -- Sodium Balance Disturbances: Deficit and Excess -- Sodium Deficit -- Diagnosis and Evaluation -- Treatment -- Sodium Excess -- Diagnosis and Evaluation -- Therapy -- Water Balance Disturbances: Deficit and Excess -- Hyponatremia -- Diagnosis and Evaluation -- Treatment -- Hypernatremia -- Diagnosis and Evaluation -- Treatment -- Acknowledgements -- References -- Potassium -- Potassium Homeostasis -- Regulation of Internal Potassium Balance -- Plasma Potassium Concentration -- Hormones -- Acid-Base Balance -- Other Factors -- Regulation of External Potassium Balance -- Renal Contribution -- Sites of Potassium Transport along the Nephron -- Proximal Tubule -- Thick Ascending Limb of the Loop of Henle (TALH) -- Distal Nephron -- Potassium Secretion -- Potassium Absorption -- Developmental Regulation of Distal Potassium Transport -- Luminal and Peritubular Factors Affecting Potassium Transport -- Sodium Delivery and Absorption -- Tubular Flow Rate -- Potassium Intake and Cellular Potassium Content -- Hormones -- Acid-Base Balance -- Contribution of the Gastrointestinal Tract -- References -- Acid-Base Homeostasis -- Introduction -- Buffering Systems -- Renal Acidification -- Proximal Mechanisms -- Na+/H+ Exchanger (NHE) -- Na+/K+ ATPase -- Carbonic Anhydrase (CA) -- Na+/HCO3-Cotransporter (NBC). Distal Mechanisms -- Loop of Henle and Thick Ascending Loop (TAL) -- Collecting Duct -- Genetics of Renal Tubular Acidosis (RTA) -- Inherited Distal Renal Tubular Acidosis -- Inherited Proximal Renal Tubular Acidosis -- Genetics of Metabolic Alkalosis -- Physiologic Response to Nonvolatile Acid Loads -- Physiologic Response to Alkaline Loads -- Acid-Base Map -- Physiologic Response to Changes in Carbon Dioxide Tension -- Molecular and Cellular Renal Regulation in Acid-Base Disorders -- Concept of Serum Anion Gap -- Concept of Urine Anion Gap -- Nutrition and Acid-Base Balance -- Acid-Base Balance in Neonates, Infants and Children -- Mechanisms of Growth Retardation in Chronic Acidosis -- Effect of Acidosis on Bone and Calcium Homeostasis -- References -- Calcium and Phosphorus -- Calcium -- Calcium Homeostasis -- Calcium Distribution in the Body -- Calcium Chemistry -- Extracellular Calcium Homeostasis -- Calcium-Sensing Receptor -- Vitamin D -- Transepithelial Calcium Transport -- Calcium Entry -- Transcytoplasmic Calcium Movement -- Calcium Exit -- Renal Calcium Transport -- Physiology and Tubular Localization -- Regulation of Renal Calcium Transport -- Phosphorus -- Phosphorus Homeostasis -- Phosphorus Distribution in the Body -- Phosphate Chemistry -- Extracellular Phosphate Homeostasis -- Intestinal Phosphate Absorption -- Cellular Aspects -- Regulation -- Molecular Mechanisms -- Renal Phosphate Transport -- Physiology and Tubular Localization -- Cellular and Molecular Aspects -- Regulation of Renal Phosphate Transport -- References -- Genetic Disorders of Calcium and Phosphate Homeostasis -- Introduction -- Regulators of Calcium and Phosphate Homeostasis -- Parathyroid Hormone (PTH) and PTH-related Peptide (PTHrP) -- Vitamin D and Its Metabolites -- Fibroblast Growth Factor 23 (FGF-23) and Other Proteins with Phosphaturic Properties. Hypercalcemia and Hypophosphatemia due to Increased Parathyroid Gland Activity. |
| Record Nr. | UNINA-9910484302503321 |
| Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||