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Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing
| Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing |
| Autore | Pörtner Ralf |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (226 p.) |
| Soggetto topico |
Technology: general issues
History of engineering & technology |
| Soggetto non controllato |
clonal cell population
phenotypic diversity inoculum train uncertainty-based cell culture model biopharmaceutical manufacturing Escherichia coli hybrid modeling machine learning model-assisted DoE quality by design upstream bioprocessing surface plasmon resonance (SPR) bioprocess monitoring biosensor quality by design (QbD) process analytical technology (PAT) biotherapeutics production vaccines production CHO DP-12 computational fluid dynamics bioreactor characterization hydrodynamic gradients process development critical shear stress Kolmogorov length scale operational space sensors cell culture spectroscopy PAT smart biomanufacturing soft-sensor Adeno-associated virus transfection PEI continuous gene therapy microcarriers bioreactor transient expression spheroid strength β-cells diabetes shear stress-guided production hydrodynamic stress Gaussian processes Bayes optimization Pareto optimization multi-objective seed train Chinese hamster ovary cells cryopreservation monoclonal antibodies N−1 perfusion process intensification upstream processing |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595072803321 |
Pörtner Ralf
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Digital twins : tools and concepts for smart biomanufacturing / / Christoph Herwig, Ralf Pörtner, Johannes Möller, editors ; with contributions by C. Appl [and thirty six more]
| Digital twins : tools and concepts for smart biomanufacturing / / Christoph Herwig, Ralf Pörtner, Johannes Möller, editors ; with contributions by C. Appl [and thirty six more] |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (267 pages) |
| Disciplina | 660.63 |
| Collana | Advances in Biochemical Engineering/Biotechnology |
| Soggetto topico | Biochemical engineering |
| ISBN | 3-030-71660-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910483653803321 |
| Cham, Switzerland : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Digital twins : applications to the design and optimization of bioprocesses / / Christoph Herwig, Ralf Pörtner, Johannes Möller, editors ; with contributions by E. Anane [and thirty two more]
| Digital twins : applications to the design and optimization of bioprocesses / / Christoph Herwig, Ralf Pörtner, Johannes Möller, editors ; with contributions by E. Anane [and thirty two more] |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (260 pages) |
| Disciplina | 660.63 |
| Collana | Advances in Biochemical Engineering/Biotechnology |
| Soggetto topico | Biochemical engineering |
| ISBN | 3-030-71656-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910484863603321 |
| Cham, Switzerland : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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