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Free Fatty Acid Receptors / / edited by Graeme Milligan, Ikuo Kimura
| Free Fatty Acid Receptors / / edited by Graeme Milligan, Ikuo Kimura |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (VIII, 256 p. 70 illus.) |
| Disciplina | 547.437 |
| Collana | Handbook of Experimental Pharmacology |
| Soggetto topico |
Pharmacology
Human physiology Diabetes Systems biology Medical biochemistry Pharmacology/Toxicology Human Physiology Systems Biology Medical Biochemistry |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Ligands at Free Fatty Acid Receptor 1 (GPR40) -- Ligands at Free Fatty Acid Receptor 2/3 (GPR43)/GPR41 -- Ligands at GPR84 -- Ligands at Free Fatty Acid Receptor 4 (GPR120) -- Homology modelling of FFA receptors -- Sensors for FFA receptors -- Key questions for translation of FFA receptors from pharmacology to medicines -- Polymorphic variation in FFA receptors. Functions and consequences -- The role and future of FFA1 as a therapeutic target -- Gut hormone regulation and secretion via FFA1 and FFA4 -- The role of FFA2 and FFA3 in metabolic regulation -- Anti-inflammatory and insulin sensitizing effects of free fatty acid receptors -- Free Fatty Acid receptors and cancer. . |
| Record Nr. | UNINA-9910164158903321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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G-Protein-Coupled Receptor Dimers / / edited by Katharine Herrick-Davis, Graeme Milligan, Giuseppe Di Giovanni
| G-Protein-Coupled Receptor Dimers / / edited by Katharine Herrick-Davis, Graeme Milligan, Giuseppe Di Giovanni |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Humana, , 2017 |
| Descrizione fisica | 1 online resource (XVII, 501 p. 70 illus., 58 illus. in color.) |
| Disciplina | 612.8 |
| Collana | The Receptors |
| Soggetto topico | Neurosciences |
| ISBN | 3-319-60174-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part I. Introduction -- 1. From Monomers to Dimers and Beyond: An Exciting Journey in the World of the G protein-coupled Receptor Family.- 2. The use of Spatial Intensity Distribution Analysis to Examine G protein-coupled Receptor Oligomerization -- 3. Advanced Microscopy Techniques for Studying G protein-coupled Receptors.- Part II. Receptors.- 4. Light Sensing G protein-coupled Receptor Rhodopsin Dimer -- 5. Extreme Vetting of Dopamine Receptor Oligomerization -- 6. Serotonin receptors.- 7. Cannabinoid and Opioid Receptor Heteromers -- 8. Di/oligomerization of Glycoprotein Hormone Receptors.- 9. Chemokine Receptor Oligomerization to Tweak Chemotactic Responses -- 10. Secretin Receptor Dimerization. Prototypic of Class B GPCR Behavior.- 11. Receptors and RAMPs -- 12. Obligatory Heterodimerization of GABAB Receptor.- 13. Metabotropic Glutamate Receptors. Part III. Assembly and Trafficking.- 14. The monomer/homodimer Equilibrium of G protein-coupled Receptors: Formation in the Secretory Pathway and Potential Functional Significance.- 15. Probing Self-assembly of G protein-coupled Receptor Oligomers in Membranes using Molecular Dynamics Modeling and Experimental Approaches.- 16. Interaction of Membrane Cholesterol with GPCRs: Implications in Receptor Oligomerization.- Part IV. Physiology and Therapeutic Potential.- 17. Allosterism within GPCR Oligomers: Back to Symmetry.- 18. Understanding the Physiological Significance of GPCR Dimers and Oligomers -- 19. Heteromers form Novel Signaling Complexes -- 20. Heteroreceptor Complexes Implicated in Parkinson’s Disease. |
| Record Nr. | UNINA-9910253940503321 |
| Cham : , : Springer International Publishing : , : Imprint : Humana, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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