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Concepts and Principles of Pharmacology : 100 Years of the Handbook of Experimental Pharmacology / / edited by James E. Barrett, Clive P. Page, Martin C. Michel
| Concepts and Principles of Pharmacology : 100 Years of the Handbook of Experimental Pharmacology / / edited by James E. Barrett, Clive P. Page, Martin C. Michel |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (viii, 466 pages) : illustrations |
| Disciplina | 615.7 |
| Collana | Handbook of Experimental Pharmacology |
| Soggetto topico |
Pharmacology
Pharmacology/Toxicology Farmacologia |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-35362-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part 1. A Century of Advances in Pharmacology -- 1. Perspectives of Pharmacology Over the Past 100 years -- 2. Emergent concepts of receptor pharmacology -- 3. The Evolving Landscape of Cancer Therapeutics -- 4. Monoclonal Antibodies: Past, Present and Future -- 5. 100 years of Drug Delivery to the Lungs -- 6. Exploiting the Diversity of Ion Channels: Ion channel Pharmacology for Pain modulation -- 7. Exploiting the Diversity of Ion Channels: Modulation of Ion Channels for Therapeutic Indications -- Part 2. Recent developments and enabling technologies in pharmacology -- 8. Genetically Encoded Fluorescent Calcium and Voltage Indicators -- 9. Mechanistic Image-Based Modeling: Concepts and Applications of Image-Based Modeling -- 10. Pharmacometabonomics: The Prediction of Drug Effects Using Metabolic Profiling -- 11. The Microbiome and its Potential for Pharmacology -- 12. Harnessing Human Microphysiology Systems as Key Experimental Models for Quantitative Systems Pharmacology -- Part 3. The future of pharmacology -- 13. The future of clinical trial design: The Transition from Hard Endpoints to Value-Based Endpoings -- 14. Placebos and the Placebo Effect in Drug Trials -- 15. Pharmacoepidemiology -- 16. Why are new drugs expensive and how can they stay affordable? . |
| Record Nr. | UNINA-9910373908003321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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G Protein-Coupled Receptor Kinases (GRKs) and Beta-Arrestins: New Insights into Disease Regulators
| G Protein-Coupled Receptor Kinases (GRKs) and Beta-Arrestins: New Insights into Disease Regulators |
| Autore | Hattori Yuichi |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (182 p.) |
| Soggetto topico |
Science: general issues
Pharmacology |
| Soggetto non controllato |
GRK
beta-arrestins cardiovascular inflammation cancer |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | G Protein-Coupled Receptor Kinases |
| Record Nr. | UNINA-9910557222003321 |
Hattori Yuichi
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Good Research Practice in Non-Clinical Pharmacology and Biomedicine / / edited by Anton Bespalov, Martin C. Michel, Thomas Steckler
| Good Research Practice in Non-Clinical Pharmacology and Biomedicine / / edited by Anton Bespalov, Martin C. Michel, Thomas Steckler |
| Autore | Bespalov Anton |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Springer Nature, 2020 |
| Descrizione fisica | 1 online resource (X, 423 p. 34 illus., 21 illus. in color.) |
| Disciplina |
615
615.1072 |
| Collana | Handbook of Experimental Pharmacology |
| Soggetto topico |
Pharmacology
Neurosciences Cardiology Oncology Pharmacology/Toxicology Oncology |
| Soggetto non controllato |
Pharmacology/Toxicology
Neurosciences Cardiology Oncology Pharmacology Neuroscience Internal Medicine reproducibility study design data analysis data reporting data integrity quality management open access Cardiovascular medicine |
| ISBN | 3-030-33656-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. Quality in Non-GxP Research Environment -- 2. Guidelines & Initiatives for Good Research Practice -- 3. Learning from principles of evidence-based medicine to optimize nonclinical research practices -- 4. General Principles of Preclinical Study Design -- 5. Resolving the tension between exploration and confirmation in preclinical biomedical research -- 6. Blinding and Randomization -- 7. Out of control? Managing baseline variability in experimental studies with control groups -- 8. Quality of Research Tools -- 9. Genetic background and sex: impact on generalizability of research findings in pharmacology studies -- 10. Building robustness intro translational research -- 11. Minimum information and quality standards for conducting, reporting, and organizing in vitro research -- 12. Minimum Information in In Vivo Research -- 13. A reckless guide to P-values: Local evidence, global errors -- 14. Electronic Lab Notebooks and Experimental Design Assistants -- 15. Data storage -- 16. Design of meta-analysis studies -- 17. Publishers’ responsibilities in promoting data quality and reproducibility -- 18. Quality governance in biomedical research -- 19. Good Research Practice – Lessons from Animal Care & Use -- 20. Research collaborations and quality in research: foes or friends? -- 21. Costs of implementing quality in research practice. |
| Record Nr. | UNINA-9910380750203321 |
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Bespalov Anton
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| Springer Nature, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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