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Metallomics : analytical techniques and speciation methods / / edited by Bernhard Michalke
| Metallomics : analytical techniques and speciation methods / / edited by Bernhard Michalke |
| Pubbl/distr/stampa | Weinhem, Germany : , : Wiley-VCH, , [2016] |
| Descrizione fisica | 1 online resource (499 p.) |
| Disciplina | 338.4779102854678 |
| Soggetto topico | Metals - Physiological effect |
| Soggetto non controllato |
Proteins
Science |
| ISBN |
3-527-69493-5
3-527-69491-9 3-527-69490-0 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Title Page; Copyright; Contents; List of Contributors; Preface; Part I Analytical Methods and Strategies in Metallomics; Chapter 1 The Position of Metallomics Within Other Omics Fields; 1.1 Introduction; 1.2 Metallome and Metallomics in Relation to Other ""-Ome"" and ""-Omics"" Fields; 1.2.1 Genomics; 1.2.2 Transcriptomics; 1.2.3 Proteomics; 1.2.4 Metabolomics; 1.2.5 Metallomics; 1.3 Is Metallomics Feasible as a Global Study of the Metallome; 1.4 Approaching the Metallome: Study of Metallome Subgroups; 1.5 Analytical Strategies in Metallomics; 1.5.1 Element Mass Spectrometry (ICP-MS)
1.5.2 Coupling Techniques1.5.3 Elemental Imaging Techniques; 1.5.4 Bioinformatic Approaches; 1.6 Functional Connections Between DNA, Proteins, Metabolites, and Metals; 1.7 Metallothiolomics as Example for Metallomics Studies of a Metallome Subgroup; 1.8 Concluding Remarks; References; Chapter 2 Coupling Techniques and Orthogonal Combination of Mass Spectrometric Techniques; 2.1 Introduction; 2.2 Analytical Techniques for Metallomics; 2.2.1 Overview about Available Separation Techniques; 2.3 Ionization Principles and Mass Spectrometric Detectors for Speciation 2.3.1 Element-Specific Detection with ICP-Based Techniques2.3.2 Electrospray Ionization-Mass Spectrometry (ESI-MS); 2.3.3 Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Techniques (MALDI-MS); 2.4 Overview about Coupling Techniques; 2.4.1 LC Couplings; 2.4.2 Coupling of CE and ICP-MS; 2.4.3 Laser Ablation (LA); 2.4.4 Gas Chromatography (GC); 2.5 Final Remarks and Outlook; References; Chapter 3 Quality Control in Speciation Analysis Using HPLC with ICP-MS and ESI MS/MS: Focus on Quantitation Strategies Using Isotope Dilution Analysis; 3.1 Introduction 3.2 Synergetic Use of Elemental and Organic Mass Spectrometry in Compound Quantitation and Quality Assurance of Food Selenium Speciation3.2.1 Quality Assurance in Species Quantitation; 3.2.2 Quality Assurance in Species Identification; 3.3 The Role of Species-Specific Isotope Dilution in Increasing Metrological Traceability for the Quantification of Bioinorganic Species; 3.3.1 IDMS and Speciation Analysis; 3.3.2 Quantitative Se Speciation in Food/Supplements by Species-Specific IDMS: Production of ""Speciated"" Reference Materials 3.3.3 Species-Specific Double IDMS Quantification of Plasma Selenoproteins: Advantages and Limitations in Comparison with the Species-Unspecific IDMS Approach3.3.4 Application of Species-Specific Double Spike IDMS to Account for Redox Exchange between Cr(III) and Cr(VI) Species: Practical Considerations for Quality Assurance; References; Chapter 4 Novel Methods for Bioimaging Including LA-ICP-MS, NanoSIMS, TEM/X-EDS, and SXRF; 4.1 Introduction; 4.2 Bioimaging by LA-ICP-MS; 4.2.1 Principle; 4.2.2 Elemental Bioimaging by LA-ICP-MS; 4.2.3 Quantitative Bioimaging by LA-ICP-MS 4.2.4 Proteomic Bioimaging by LA-ICP-MS |
| Record Nr. | UNINA-9910830000203321 |
| Weinhem, Germany : , : Wiley-VCH, , [2016] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nutzen-risiko-bewertung von mineralstoffen und spurenelementen : biochemische, physiologische und toxikologische aspekte
| Nutzen-risiko-bewertung von mineralstoffen und spurenelementen : biochemische, physiologische und toxikologische aspekte |
| Autore | Bernhard Michalke |
| Pubbl/distr/stampa | KIT Scientific Publishing |
| Descrizione fisica | 1 online resource (204 pages) |
| Soggetto topico |
Human Anatomy & Physiology
Health & Biological Sciences Animal Biochemistry |
| Soggetto non controllato |
Nahrungsergänzungsmittel
Zink Spurenelemente Zytotoxizität Genotoxizität Kupfer |
| ISBN | 2-8218-5147-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ger |
| Record Nr. | UNINA-9910140100003321 |
Bernhard Michalke
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| KIT Scientific Publishing | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Selenium / / edited by Bernhard Michalke
| Selenium / / edited by Bernhard Michalke |
| Edizione | [1st ed. 2018.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
| Descrizione fisica | 1 online resource (517 pages) |
| Disciplina | 669.79 |
| Collana | Molecular and Integrative Toxicology |
| Soggetto topico |
Pharmacology
Medical biochemistry Molecular biology Pharmacology/Toxicology Medical Biochemistry Molecular Medicine |
| ISBN | 3-319-95390-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part I - Overview: 1. Selenium in Human Health and Disease: an Overview -- Part II - Bioaccessibility and Dietary Aspects of Selenium: 2. Selenium in Soils and Crops -- 3. Dietary Aspects for Selenium and/or Selenium Compounds -- Part III - Genes, Proteins, Pathways, and Metabolism Related to Selenium: 4. Contribution of the Yeast Saccharomyces Cerevisiae Model to Understand the Mechanisms of Selenium Toxicity -- 5. Selenium Metabolism, Regulation And Sex Differences In Mammals -- Part IV - The Role of Selenium within Redox System, Inflammation, and Thyroid Interaction: 6. Oxidative Stress, Selenium Redox Systems Including GPX / TXNRD Families -- 7. Selenium and Inflammatory Mediators -- 8. Selenium and Thyroid Function -- Part V - The Role of Selenium in Neurodevelopment and Neurological Disorders: 9. Selenium and Neurodevelopment -- 10. Selenium and Autism Spectrum Disorder -- 11. Selenium in Ischemic Stroke -- 12. Selenium neurotoxicity and Amyotrophic Lateral Sclerosis: An Epidemiologic Perspective -- Part VI - The Role of Selenium in Cancer: 13. Therapeutic Potential of Selenium Compounds in the Treatment of Cancer -- 14. Selenocystine and Cancer -- 15. Selenium in Radiation Oncology -- Part VII - The Role of Selenium in Various Diseases and Health Issues: 16. Selenium and Cardiovascular Disease: Epidemiological Evidence of a Possible U-Shaped Relationship -- 17. Selenium and Diabetes -- 18. Uncovering the Importance of Selenium in Muscle Disease -- 19. Selenium in Immune Response and Intensive Care -- 20. Selenium and Toxicological Aspects: Cytotoxicity, Cellular Bioavailability and Biotransformation of Se-Species -- 21. Selenium Nanoparticles - Biomedical Application -- 22. Selenium Interactions with Other Trace Elements, with Nutrients (and Drugs) in Humans -- Part VIII - Selenium Analytics, Speciation and Biomonitoring: 23. Biomarkers of Selenium Status -- 24. Human Biomonitoring of Selenium Exposure -- 25. Bioanalytical Chemistry of Selenium. |
| Record Nr. | UNINA-9910298409703321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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