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Encyclopedia of Complexity and Systems Science [[electronic resource]]
| Encyclopedia of Complexity and Systems Science [[electronic resource]] |
| Edizione | [1st ed. 2009.] |
| Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Springer, , 2009 |
| Descrizione fisica | 1 online resource (eReference.) |
| Disciplina | 003 |
| Altri autori (Persone) | MeyersRobert A <1936-> (Robert Allen) |
| Collana | Springer reference Encyclopedia of complexity and systems science |
| Soggetto topico |
Statistical physics
Dynamical systems Probabilities Chemistry Bioinformatics Economics Management science Earth sciences Complex Systems Probability Theory and Stochastic Processes Chemistry/Food Science, general Economics, general Earth Sciences, general |
| ISBN | 0-387-30440-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | v. 1. A-Cl -- v. 2. Co-D -- v. 3. E -- v. 4. F-G -- v. 5. H-L -- v. 6. M-N -- v. 7. O-P -- v. 8. Q-R -- v.9. S -- v. 10. T-Z -- v. 11. Index. |
| Record Nr. | UNINA-9910484792503321 |
| New York, NY : , : Springer New York : , : Imprint : Springer, , 2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Epigenetic regulation and epigenomics [[electronic resource] /] / edited by Robert A. Meyers
| Epigenetic regulation and epigenomics [[electronic resource] /] / edited by Robert A. Meyers |
| Pubbl/distr/stampa | Weinheim, : Wiley-Blackwell, c2012 |
| Descrizione fisica | 1 online resource (1239 p.) |
| Disciplina | 572.865 |
| Altri autori (Persone) | MeyersRobert A <1936-> (Robert Allen) |
| Collana | Advances in molecular biology and medicine |
| Soggetto topico |
Genetic regulation
Epigenesis |
| Soggetto genere / forma | Electronic books. |
| ISBN |
3-527-66862-4
1-283-64410-X 3-527-66861-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Epigenetic Regulation and Epigenomics; Contents; Preface and Commentary; List of Contributors; Part I Analytical Methods; 1 RNA Methodologies; 1 Introduction; 2 Subpopulations of RNA; 3 Goals in the Purification of RNA; 4 Methods of Cellular Disruption and RNA Recovery; 5 Inhibition of Ribonuclease Activity; 6 Methods for the Analysis of RNA; 7 Summary; References; 2 All Things ChIP: ChIP-Chip, ChIP-Seq, ChIP-PCR; 1 Introduction; 2 Protein-DNA Binding; 3 ChIP Protocol; 4 ChIP-PCR, ChIP-Chip, or ChIP-Seq. Which Should be Chosen?; 5 Experimental Considerations; 6 Calculating IP Enrichment
7 Special Analysis Considerations8 Conclusions; References; 3 Methods for DNA Methylation Analysis; 1 Introduction; 2 Methods of DNA Methylation Analysis; 3 Concluding Remarks; Acknowledgments; References; 4 DNA Methylation Analysis by MALDI Mass Spectrometry; Abbreviations; 1 Introduction to DNA Methylation; 2 Epigenetics and Disease; 3 DNA Methylation Content Analysis by Mass Spectrometry; 4 Specific DNA Methylation Analysis; 5 Introduction to MALDI; 6 Problems of MALDI Analysis of; 7 DNA Sequencing with MALDI Mass Spectrometry Readout 8 Primer Extension for the Interrogation of Specific Positions9 Quantification; 10 Automation of Sample Preparation, Data Accumulation, and Analysis; 11 Positioning of MALDI MS for DNA Methylation Analysis; 12 Applications of DNA Methylation Analysis by Mass Spectrometry; 13 DNA Methylation Analysis for Tumor Classification; 14 DNA Methylation Analysis for Prognosis and Response to Treatment; 15 Prenatal Diagnosis; 16 Conclusions; References; 5 Tag Sequencing; 1 Library Construction; 2 Advanced Sequencing Technologies; 3 Data Analysis and Bioinformatics; 4 Applications of Tag Sequencing 5 Clinical Applications of Tag Sequencing6 Future Perspectives; Acknowledgments; References; Part II Basic Molecular Mechanisms; 6 Heterochromatin and Euchromatin - Organization, Boundaries and Gene Regulation; 1 Properties and Functions of Heterochromatin; 2 Euchromatin Formation; 3 Boundaries between Heterochromatin and Euchromatin; 4 Insulating against Active Chromatin; Acknowledgments; References; 7 Regulation of Gene Expression; 1 Introduction; 2 Regulation of Gene Expression in Prokaryotes; 3 Regulation of Gene Expression in Eukaryotes; 4 RNA Splicing 5 Role of microRNAs (miRNAs) in the Regulation of Gene Expression6 Chromatin Structure and the Control of Gene Expression; 7 Epigenetic Control of Gene Expression; 8 Gene Regulation by Hormonal Action; 9 Post-Transcriptional Regulation of mRNA; 10 Transport of Processed mRNA to the Cytoplasm; 11 Regulation of Gene Expression at the Level of Translation; Acknowledgments; References; 8 Molecular Genetics of Genomic Imprinting; 1 Genomic Imprinting in Mammals; 2 Imprinted Genes; 3 Molecular Mechanisms; 4 Imprinting and Disease; 5 Human Reproduction; 6 Evolution of Imprinting; References 9 Nuclear Transfer for Cloning Animals |
| Record Nr. | UNINA-9910462158003321 |
| Weinheim, : Wiley-Blackwell, c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Epigenetic regulation and epigenomics [[electronic resource] /] / edited by Robert A. Meyers
| Epigenetic regulation and epigenomics [[electronic resource] /] / edited by Robert A. Meyers |
| Pubbl/distr/stampa | Weinheim, : Wiley-Blackwell, c2012 |
| Descrizione fisica | 1 online resource (1239 p.) |
| Disciplina | 572.865 |
| Altri autori (Persone) | MeyersRobert A <1936-> (Robert Allen) |
| Collana | Advances in molecular biology and medicine |
| Soggetto topico |
Genetic regulation
Epigenesis |
| ISBN |
3-527-66862-4
1-283-64410-X 3-527-66861-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Epigenetic Regulation and Epigenomics; Contents; Preface and Commentary; List of Contributors; Part I Analytical Methods; 1 RNA Methodologies; 1 Introduction; 2 Subpopulations of RNA; 3 Goals in the Purification of RNA; 4 Methods of Cellular Disruption and RNA Recovery; 5 Inhibition of Ribonuclease Activity; 6 Methods for the Analysis of RNA; 7 Summary; References; 2 All Things ChIP: ChIP-Chip, ChIP-Seq, ChIP-PCR; 1 Introduction; 2 Protein-DNA Binding; 3 ChIP Protocol; 4 ChIP-PCR, ChIP-Chip, or ChIP-Seq. Which Should be Chosen?; 5 Experimental Considerations; 6 Calculating IP Enrichment
7 Special Analysis Considerations8 Conclusions; References; 3 Methods for DNA Methylation Analysis; 1 Introduction; 2 Methods of DNA Methylation Analysis; 3 Concluding Remarks; Acknowledgments; References; 4 DNA Methylation Analysis by MALDI Mass Spectrometry; Abbreviations; 1 Introduction to DNA Methylation; 2 Epigenetics and Disease; 3 DNA Methylation Content Analysis by Mass Spectrometry; 4 Specific DNA Methylation Analysis; 5 Introduction to MALDI; 6 Problems of MALDI Analysis of; 7 DNA Sequencing with MALDI Mass Spectrometry Readout 8 Primer Extension for the Interrogation of Specific Positions9 Quantification; 10 Automation of Sample Preparation, Data Accumulation, and Analysis; 11 Positioning of MALDI MS for DNA Methylation Analysis; 12 Applications of DNA Methylation Analysis by Mass Spectrometry; 13 DNA Methylation Analysis for Tumor Classification; 14 DNA Methylation Analysis for Prognosis and Response to Treatment; 15 Prenatal Diagnosis; 16 Conclusions; References; 5 Tag Sequencing; 1 Library Construction; 2 Advanced Sequencing Technologies; 3 Data Analysis and Bioinformatics; 4 Applications of Tag Sequencing 5 Clinical Applications of Tag Sequencing6 Future Perspectives; Acknowledgments; References; Part II Basic Molecular Mechanisms; 6 Heterochromatin and Euchromatin - Organization, Boundaries and Gene Regulation; 1 Properties and Functions of Heterochromatin; 2 Euchromatin Formation; 3 Boundaries between Heterochromatin and Euchromatin; 4 Insulating against Active Chromatin; Acknowledgments; References; 7 Regulation of Gene Expression; 1 Introduction; 2 Regulation of Gene Expression in Prokaryotes; 3 Regulation of Gene Expression in Eukaryotes; 4 RNA Splicing 5 Role of microRNAs (miRNAs) in the Regulation of Gene Expression6 Chromatin Structure and the Control of Gene Expression; 7 Epigenetic Control of Gene Expression; 8 Gene Regulation by Hormonal Action; 9 Post-Transcriptional Regulation of mRNA; 10 Transport of Processed mRNA to the Cytoplasm; 11 Regulation of Gene Expression at the Level of Translation; Acknowledgments; References; 8 Molecular Genetics of Genomic Imprinting; 1 Genomic Imprinting in Mammals; 2 Imprinted Genes; 3 Molecular Mechanisms; 4 Imprinting and Disease; 5 Human Reproduction; 6 Evolution of Imprinting; References 9 Nuclear Transfer for Cloning Animals |
| Record Nr. | UNINA-9910785805403321 |
| Weinheim, : Wiley-Blackwell, c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Epigenetic regulation and epigenomics / / edited by Robert A. Meyers
| Epigenetic regulation and epigenomics / / edited by Robert A. Meyers |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Weinheim, : Wiley-Blackwell, c2012 |
| Descrizione fisica | 1 online resource (1239 p.) |
| Disciplina | 572.865 |
| Altri autori (Persone) | MeyersRobert A <1936-> (Robert Allen) |
| Collana | Advances in molecular biology and medicine |
| Soggetto topico |
Genetic regulation
Epigenesis |
| ISBN |
3-527-66862-4
1-283-64410-X 3-527-66861-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Epigenetic Regulation and Epigenomics; Contents; Preface and Commentary; List of Contributors; Part I Analytical Methods; 1 RNA Methodologies; 1 Introduction; 2 Subpopulations of RNA; 3 Goals in the Purification of RNA; 4 Methods of Cellular Disruption and RNA Recovery; 5 Inhibition of Ribonuclease Activity; 6 Methods for the Analysis of RNA; 7 Summary; References; 2 All Things ChIP: ChIP-Chip, ChIP-Seq, ChIP-PCR; 1 Introduction; 2 Protein-DNA Binding; 3 ChIP Protocol; 4 ChIP-PCR, ChIP-Chip, or ChIP-Seq. Which Should be Chosen?; 5 Experimental Considerations; 6 Calculating IP Enrichment
7 Special Analysis Considerations8 Conclusions; References; 3 Methods for DNA Methylation Analysis; 1 Introduction; 2 Methods of DNA Methylation Analysis; 3 Concluding Remarks; Acknowledgments; References; 4 DNA Methylation Analysis by MALDI Mass Spectrometry; Abbreviations; 1 Introduction to DNA Methylation; 2 Epigenetics and Disease; 3 DNA Methylation Content Analysis by Mass Spectrometry; 4 Specific DNA Methylation Analysis; 5 Introduction to MALDI; 6 Problems of MALDI Analysis of; 7 DNA Sequencing with MALDI Mass Spectrometry Readout 8 Primer Extension for the Interrogation of Specific Positions9 Quantification; 10 Automation of Sample Preparation, Data Accumulation, and Analysis; 11 Positioning of MALDI MS for DNA Methylation Analysis; 12 Applications of DNA Methylation Analysis by Mass Spectrometry; 13 DNA Methylation Analysis for Tumor Classification; 14 DNA Methylation Analysis for Prognosis and Response to Treatment; 15 Prenatal Diagnosis; 16 Conclusions; References; 5 Tag Sequencing; 1 Library Construction; 2 Advanced Sequencing Technologies; 3 Data Analysis and Bioinformatics; 4 Applications of Tag Sequencing 5 Clinical Applications of Tag Sequencing6 Future Perspectives; Acknowledgments; References; Part II Basic Molecular Mechanisms; 6 Heterochromatin and Euchromatin - Organization, Boundaries and Gene Regulation; 1 Properties and Functions of Heterochromatin; 2 Euchromatin Formation; 3 Boundaries between Heterochromatin and Euchromatin; 4 Insulating against Active Chromatin; Acknowledgments; References; 7 Regulation of Gene Expression; 1 Introduction; 2 Regulation of Gene Expression in Prokaryotes; 3 Regulation of Gene Expression in Eukaryotes; 4 RNA Splicing 5 Role of microRNAs (miRNAs) in the Regulation of Gene Expression6 Chromatin Structure and the Control of Gene Expression; 7 Epigenetic Control of Gene Expression; 8 Gene Regulation by Hormonal Action; 9 Post-Transcriptional Regulation of mRNA; 10 Transport of Processed mRNA to the Cytoplasm; 11 Regulation of Gene Expression at the Level of Translation; Acknowledgments; References; 8 Molecular Genetics of Genomic Imprinting; 1 Genomic Imprinting in Mammals; 2 Imprinted Genes; 3 Molecular Mechanisms; 4 Imprinting and Disease; 5 Human Reproduction; 6 Evolution of Imprinting; References 9 Nuclear Transfer for Cloning Animals |
| Record Nr. | UNINA-9910823889103321 |
| Weinheim, : Wiley-Blackwell, c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Frontiers in developmental biology / / edited by Robert A. Meyers
| Frontiers in developmental biology / / edited by Robert A. Meyers |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Co., , [2019] |
| Descrizione fisica | 1 online resource (613 pages) |
| Disciplina | 571.8 |
| Collana | Advances in molecular biology and medicine |
| Soggetto topico | Developmental biology |
| ISBN | 3-527-68589-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910793570503321 |
| Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Co., , [2019] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Frontiers in developmental biology / / edited by Robert A. Meyers
| Frontiers in developmental biology / / edited by Robert A. Meyers |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Co., , [2019] |
| Descrizione fisica | 1 online resource (613 pages) |
| Disciplina | 571.8 |
| Collana | Advances in molecular biology and medicine |
| Soggetto topico | Developmental biology |
| ISBN | 3-527-68589-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910810702203321 |
| Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Co., , [2019] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Systems biology [[electronic resource] /] / edited by Robert A. Meyers
| Systems biology [[electronic resource] /] / edited by Robert A. Meyers |
| Pubbl/distr/stampa | Weinheim, : Wiley-Blackwell, 2012 |
| Descrizione fisica | 1 online resource (728 p.) |
| Disciplina | 570.285 |
| Altri autori (Persone) | MeyersRobert A <1936-> (Robert Allen) |
| Collana | Advances in molecular biology and medicine |
| Soggetto topico |
Systems biology
Biology |
| Soggetto genere / forma | Electronic books. |
| ISBN |
3-527-66859-4
1-283-64413-4 3-527-33496-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Systems Biology; Contents; Preface and Commentary; List of Contributors; Part I Biological Basis of Systems Biology; 1 Systems Biology; 1 Introduction; 2 What Is Systems Understanding?; 3 Why Are Biological Systems Different?; 3.1 Biological Complexity; 3.2 Global Properties of Biological Systems; 4 Systems Biology Modeling; 4.1 Network Biology; 4.2 Dynamic Network Models; 4.3 Reaction-Diffusion Models; 4.4 Holism versus Reductionism: The Global Dynamics of Networks; 4.5 Modeling Resources and Standards; 5 Future Prospects of Systems Biology; 5.1 Synthetic Biology
5.2 Conclusions: Where Are We?References; 2 Developmental Cell Biology; 1 Historical Perspective; 1.1 Origins of Cell Biology; 1.2 Origins of Developmental Biology; 1.3 Relationship between Cell and Developmental Biology; 2 Cell Activities Underlying Development; 2.1 Intracellular Signal Transduction; 2.2 Cell Signaling; 2.3 Cell-Cell Interactions; 2.4 Cell-Matrix Interaction; 2.3 Cell-Cell Interactions; 2.4 Cell-Matrix Interaction; 3 Cell Differentiation; 3 Cell Differentiation; 4 The Cell Cycle and Development; 4 The Cell Cycle and Development; 5 Organogenesis; 6 Stem Cells; 5 Organogenesis 6 Stem Cells7 Chimeras; 7 Chimeras; 8 microRNAs (miRNAs); 9 In vitro Fertilization; References; 8 microRNAs (miRNAs); 9 In vitro Fertilization; References; 3 Principles and Applications of Embryogenomics; 3 Principles and Applications of Embryogenomics; 1 Introduction; 1 Introduction; 2 Approaches; 2.1 Overview; 2 Approaches; 2.1 Overview; 2.2 Large-Scale Analysis of Gene Expression at the Transcriptome Level; 2.2 Large-Scale Analysis of Gene Expression at the Transcriptome Level; 2.3 Large-Scale Analysis of Gene Expression at the Proteome Level 2.4 Development and Evolution: Comparative Genomics2.5 Functional Genomics/Large-Scale Manipulation of Expression; 2.6 Computational Approaches; 3 Model Organisms for Embryogenomics; 3.1 Non-Mammalian Animals; 3.2 Mammalian; 3.3 Plants; 3.4 Suitability of Approaches for Particular Model Organisms Applied to the Study of Development; 4 Conclusions; References; 4 Interactome; 1 Introduction; 2 Experimental Techniques for DetectingProtein Interactions; 3 Computational Prediction of Protein Interactions; 3.1 Interaction Prediction from the Gene Patterns Across Genomes 3.2 Predicting Interaction from Sequence Coevolution3.3 Domain Interactions; 3.4 Coexpression Networks; 4 Exploring the Topology of the Interactome; 4.1 Global Properties; 4.2 Network Centrality and Protein Essentiality; 4.3 Network Modules; 4.4 Network Motifs and Related Concepts; 5 Comparing Protein-Protein Interaction Networks; 6 Databases of Protein and Domain Interactions; 7 Applications; 7.1 Predicting Protein Function; 7.2 Application to Human Diseases; 8 Looking Ahead: Towards the Dynamic Interactome; Acknowledgments; References; 5 Protein Abundance Variation; 1 Introduction 2 Biochemical Aspects Affecting Protein Abundance in Prokaryotes |
| Record Nr. | UNINA-9910462156003321 |
| Weinheim, : Wiley-Blackwell, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Systems biology [[electronic resource] /] / edited by Robert A. Meyers
| Systems biology [[electronic resource] /] / edited by Robert A. Meyers |
| Pubbl/distr/stampa | Weinheim, : Wiley-Blackwell, 2012 |
| Descrizione fisica | 1 online resource (728 p.) |
| Disciplina | 570.285 |
| Altri autori (Persone) | MeyersRobert A <1936-> (Robert Allen) |
| Collana | Advances in molecular biology and medicine |
| Soggetto topico |
Systems biology
Biology |
| ISBN |
3-527-66859-4
1-283-64413-4 3-527-33496-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Systems Biology; Contents; Preface and Commentary; List of Contributors; Part I Biological Basis of Systems Biology; 1 Systems Biology; 1 Introduction; 2 What Is Systems Understanding?; 3 Why Are Biological Systems Different?; 3.1 Biological Complexity; 3.2 Global Properties of Biological Systems; 4 Systems Biology Modeling; 4.1 Network Biology; 4.2 Dynamic Network Models; 4.3 Reaction-Diffusion Models; 4.4 Holism versus Reductionism: The Global Dynamics of Networks; 4.5 Modeling Resources and Standards; 5 Future Prospects of Systems Biology; 5.1 Synthetic Biology
5.2 Conclusions: Where Are We?References; 2 Developmental Cell Biology; 1 Historical Perspective; 1.1 Origins of Cell Biology; 1.2 Origins of Developmental Biology; 1.3 Relationship between Cell and Developmental Biology; 2 Cell Activities Underlying Development; 2.1 Intracellular Signal Transduction; 2.2 Cell Signaling; 2.3 Cell-Cell Interactions; 2.4 Cell-Matrix Interaction; 2.3 Cell-Cell Interactions; 2.4 Cell-Matrix Interaction; 3 Cell Differentiation; 3 Cell Differentiation; 4 The Cell Cycle and Development; 4 The Cell Cycle and Development; 5 Organogenesis; 6 Stem Cells; 5 Organogenesis 6 Stem Cells7 Chimeras; 7 Chimeras; 8 microRNAs (miRNAs); 9 In vitro Fertilization; References; 8 microRNAs (miRNAs); 9 In vitro Fertilization; References; 3 Principles and Applications of Embryogenomics; 3 Principles and Applications of Embryogenomics; 1 Introduction; 1 Introduction; 2 Approaches; 2.1 Overview; 2 Approaches; 2.1 Overview; 2.2 Large-Scale Analysis of Gene Expression at the Transcriptome Level; 2.2 Large-Scale Analysis of Gene Expression at the Transcriptome Level; 2.3 Large-Scale Analysis of Gene Expression at the Proteome Level 2.4 Development and Evolution: Comparative Genomics2.5 Functional Genomics/Large-Scale Manipulation of Expression; 2.6 Computational Approaches; 3 Model Organisms for Embryogenomics; 3.1 Non-Mammalian Animals; 3.2 Mammalian; 3.3 Plants; 3.4 Suitability of Approaches for Particular Model Organisms Applied to the Study of Development; 4 Conclusions; References; 4 Interactome; 1 Introduction; 2 Experimental Techniques for DetectingProtein Interactions; 3 Computational Prediction of Protein Interactions; 3.1 Interaction Prediction from the Gene Patterns Across Genomes 3.2 Predicting Interaction from Sequence Coevolution3.3 Domain Interactions; 3.4 Coexpression Networks; 4 Exploring the Topology of the Interactome; 4.1 Global Properties; 4.2 Network Centrality and Protein Essentiality; 4.3 Network Modules; 4.4 Network Motifs and Related Concepts; 5 Comparing Protein-Protein Interaction Networks; 6 Databases of Protein and Domain Interactions; 7 Applications; 7.1 Predicting Protein Function; 7.2 Application to Human Diseases; 8 Looking Ahead: Towards the Dynamic Interactome; Acknowledgments; References; 5 Protein Abundance Variation; 1 Introduction 2 Biochemical Aspects Affecting Protein Abundance in Prokaryotes |
| Record Nr. | UNINA-9910785805503321 |
| Weinheim, : Wiley-Blackwell, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Systems biologY / / edited by Robert A. Meyers
| Systems biologY / / edited by Robert A. Meyers |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Weinheim, : Wiley-Blackwell, 2012 |
| Descrizione fisica | 1 online resource (728 p.) |
| Disciplina | 570.285 |
| Altri autori (Persone) | MeyersRobert A <1936-> (Robert Allen) |
| Collana | Advances in molecular biology and medicine |
| Soggetto topico |
Systems biology
Biology |
| ISBN |
3-527-66859-4
1-283-64413-4 3-527-33496-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Systems Biology; Contents; Preface and Commentary; List of Contributors; Part I Biological Basis of Systems Biology; 1 Systems Biology; 1 Introduction; 2 What Is Systems Understanding?; 3 Why Are Biological Systems Different?; 3.1 Biological Complexity; 3.2 Global Properties of Biological Systems; 4 Systems Biology Modeling; 4.1 Network Biology; 4.2 Dynamic Network Models; 4.3 Reaction-Diffusion Models; 4.4 Holism versus Reductionism: The Global Dynamics of Networks; 4.5 Modeling Resources and Standards; 5 Future Prospects of Systems Biology; 5.1 Synthetic Biology
5.2 Conclusions: Where Are We?References; 2 Developmental Cell Biology; 1 Historical Perspective; 1.1 Origins of Cell Biology; 1.2 Origins of Developmental Biology; 1.3 Relationship between Cell and Developmental Biology; 2 Cell Activities Underlying Development; 2.1 Intracellular Signal Transduction; 2.2 Cell Signaling; 2.3 Cell-Cell Interactions; 2.4 Cell-Matrix Interaction; 2.3 Cell-Cell Interactions; 2.4 Cell-Matrix Interaction; 3 Cell Differentiation; 3 Cell Differentiation; 4 The Cell Cycle and Development; 4 The Cell Cycle and Development; 5 Organogenesis; 6 Stem Cells; 5 Organogenesis 6 Stem Cells7 Chimeras; 7 Chimeras; 8 microRNAs (miRNAs); 9 In vitro Fertilization; References; 8 microRNAs (miRNAs); 9 In vitro Fertilization; References; 3 Principles and Applications of Embryogenomics; 3 Principles and Applications of Embryogenomics; 1 Introduction; 1 Introduction; 2 Approaches; 2.1 Overview; 2 Approaches; 2.1 Overview; 2.2 Large-Scale Analysis of Gene Expression at the Transcriptome Level; 2.2 Large-Scale Analysis of Gene Expression at the Transcriptome Level; 2.3 Large-Scale Analysis of Gene Expression at the Proteome Level 2.4 Development and Evolution: Comparative Genomics2.5 Functional Genomics/Large-Scale Manipulation of Expression; 2.6 Computational Approaches; 3 Model Organisms for Embryogenomics; 3.1 Non-Mammalian Animals; 3.2 Mammalian; 3.3 Plants; 3.4 Suitability of Approaches for Particular Model Organisms Applied to the Study of Development; 4 Conclusions; References; 4 Interactome; 1 Introduction; 2 Experimental Techniques for DetectingProtein Interactions; 3 Computational Prediction of Protein Interactions; 3.1 Interaction Prediction from the Gene Patterns Across Genomes 3.2 Predicting Interaction from Sequence Coevolution3.3 Domain Interactions; 3.4 Coexpression Networks; 4 Exploring the Topology of the Interactome; 4.1 Global Properties; 4.2 Network Centrality and Protein Essentiality; 4.3 Network Modules; 4.4 Network Motifs and Related Concepts; 5 Comparing Protein-Protein Interaction Networks; 6 Databases of Protein and Domain Interactions; 7 Applications; 7.1 Predicting Protein Function; 7.2 Application to Human Diseases; 8 Looking Ahead: Towards the Dynamic Interactome; Acknowledgments; References; 5 Protein Abundance Variation; 1 Introduction 2 Biochemical Aspects Affecting Protein Abundance in Prokaryotes |
| Record Nr. | UNINA-9910825050403321 |
| Weinheim, : Wiley-Blackwell, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Translational medicine Molecular pharmacology and drug discovery . Volume 1, and 2 : molecular pharmacology and drug discovery / / edited by Robert A. Meyers
| Translational medicine Molecular pharmacology and drug discovery . Volume 1, and 2 : molecular pharmacology and drug discovery / / edited by Robert A. Meyers |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH, , 2018 |
| Descrizione fisica | 1 online resource (1,058 pages) |
| Disciplina | 615.19 |
| Collana | Advances in Molecular Biology and Medicine |
| Soggetto topico |
Drug development
Molecular pharmacology |
| ISBN |
3-527-68721-1
3-527-68719-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Volume 1 -- Volume 2. |
| Record Nr. | UNINA-9910795411103321 |
| Weinheim, Germany : , : Wiley-VCH, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
