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Metathesis in natural product synthesis [[electronic resource] ] : strategies, substrates and catalysts / / edited by Janine Cossy, Stellios Arseniyadis, and Christophe Meyer ; with a foreword by Robert H. Grubbs
| Metathesis in natural product synthesis [[electronic resource] ] : strategies, substrates and catalysts / / edited by Janine Cossy, Stellios Arseniyadis, and Christophe Meyer ; with a foreword by Robert H. Grubbs |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2010 |
| Descrizione fisica | 1 online resource (414 p.) |
| Disciplina | 547.2 |
| Altri autori (Persone) |
CossyJanine
ArseniyadisS (Stellios) MeyerChristophe |
| Soggetto topico |
Natural products - Synthesis
Metathesis (Chemistry) |
| ISBN |
3-527-64208-0
1-283-51405-2 9786613826503 3-527-62963-7 3-527-62962-9 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Metathesis in Natural Product Synthesis: Strategies, Substrates and Catalysts; Contents; Foreword; Preface; List of Catalysts; List of Contributors; Abbreviations; 1 Synthesis of Natural Products Containing Medium-size Carbocycles by Ring-closing Alkene Metathesis; 1.1 Introduction; 1.2 Formation of Five-membered Carbocycles by RCM; 1.3 Formation of Six-membered Carbocycles by RCM; 1.4 Formation of Seven-membered Carbocycles by RCM; 1.5 Formation of Eight-membered Carbocycles by RCM; 1.6 Formation of Nine-membered Carbocycles by RCM; 1.7 Formation of 10-membered Carbocycles by RCM
1.8 ConclusionReferences; 2 Natural Products Containing Medium-sized Nitrogen Heterocycles Synthesized by Ring-closing Alkene Metathesis; 2.1 Introduction; 2.2 Five-membered Nitrogen Heterocycles; 2.2.1 Dihydropyrroles; 2.2.2 Pyrrolidine Alkaloids; 2.2.2.1 Pyrrolidines; 2.2.2.2 Dipyrrolidines; 2.2.2.3 Polyhydroxypyrrolidines; 2.2.3 Indolizidine Alkaloids; 2.2.3.1 Polycyclic Indolizidines; 2.2.3.2 Polyhydroxyindolizidines; 2.2.4 Pyrrolizidine Alkaloids; 2.3 Six-membered Nitrogen Heterocycles; 2.3.1 Piperidine Alkaloids; 2.3.1.1 Piperidines; 2.3.1.2 Piperidine Carboxylic Acids 2.3.1.3 Piperidones2.3.1.4 Polyhydroxypiperidines; 2.3.2 Indolizidine Alkaloids; 2.3.3 Quinolizidine Alkaloids; 2.4 Seven-membered Nitrogen Heterocycles; 2.5 Eight-membered Nitrogen Heterocycles; 2.6 Conclusion; References; 3 Synthesis of Natural Products Containing Medium-size Oxygen Heterocycles by Ring-closing Alkene Metathesis; 3.1 Introduction; 3.2 General RCM Approaches to Medium Rings; 3.3 Laurencin; 3.4 Eunicellins/Eleutherobin; 3.5 Helianane; 3.6 Octalactin A; 3.7 Microcarpalide and the Herbarums; 3.8 Marine Ladder Toxins; 3.8.1 Ciguatoxin; 3.8.2 Brevetoxin 3.8.3 Gambierol, Gambieric Acid, Olefinic-ester Cyclizations3.9 Conclusion; Acknowledgments; References; 4 Phosphorus and Sulfur Heterocycles via Ring-closing Metathesis: Application in Natural Product Synthesis; 4.1 Introduction; 4.2 Synthesis and Reactivity of Sultones Derived from RCM; 4.3 Total Synthesis of the Originally Proposed Structure of (±)-Mycothiazole; 4.4 Synthesis and Reactivity of Phosphates from RCM; 4.5 Applications of Phosphate Tethers in the Synthesis of Dolabelide C; 4.6 Conclusion; Acknowledgment; References 5 Synthesis of Natural Products Containing Macrocycles by Alkene Ring-closing Metathesis5.1 Introduction; 5.2 Organization of the Chapter; 5.3 Macrocyclic Polyketides; 5.3.1 Resorcinylic Macrolides; 5.3.2 Salicylate Macrolides; 5.3.3 Other Antibiotic Macrolides; 5.3.4 Macrocyclic Musk; 5.3.5 Epothilones; 5.3.6 Amphidinolides; 5.3.7 Other Polyketides; 5.3.8 Natural Cyclophanes; 5.4 Terpenoids; 5.4.1 Diterpenoids; 5.4.2 Macrocyclic Lipids; 5.5 Macrocycles of Amino Acid Origin; 5.5.1 Macrolactams; 5.5.2 Cyclodepsipeptides; 5.5.3 Alkaloids; 5.6 Macrocyclic Glycolipids; 5.7 Conclusions and Outlook References |
| Record Nr. | UNINA-9910140481003321 |
| Weinheim, : Wiley-VCH, c2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Metathesis in natural product synthesis [[electronic resource] ] : strategies, substrates and catalysts / / edited by Janine Cossy, Stellios Arseniyadis, and Christophe Meyer ; with a foreword by Robert H. Grubbs
| Metathesis in natural product synthesis [[electronic resource] ] : strategies, substrates and catalysts / / edited by Janine Cossy, Stellios Arseniyadis, and Christophe Meyer ; with a foreword by Robert H. Grubbs |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2010 |
| Descrizione fisica | 1 online resource (414 p.) |
| Disciplina | 547.2 |
| Altri autori (Persone) |
CossyJanine
ArseniyadisS (Stellios) MeyerChristophe |
| Soggetto topico |
Natural products - Synthesis
Metathesis (Chemistry) |
| ISBN |
3-527-64208-0
1-283-51405-2 9786613826503 3-527-62963-7 3-527-62962-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Metathesis in Natural Product Synthesis: Strategies, Substrates and Catalysts; Contents; Foreword; Preface; List of Catalysts; List of Contributors; Abbreviations; 1 Synthesis of Natural Products Containing Medium-size Carbocycles by Ring-closing Alkene Metathesis; 1.1 Introduction; 1.2 Formation of Five-membered Carbocycles by RCM; 1.3 Formation of Six-membered Carbocycles by RCM; 1.4 Formation of Seven-membered Carbocycles by RCM; 1.5 Formation of Eight-membered Carbocycles by RCM; 1.6 Formation of Nine-membered Carbocycles by RCM; 1.7 Formation of 10-membered Carbocycles by RCM
1.8 ConclusionReferences; 2 Natural Products Containing Medium-sized Nitrogen Heterocycles Synthesized by Ring-closing Alkene Metathesis; 2.1 Introduction; 2.2 Five-membered Nitrogen Heterocycles; 2.2.1 Dihydropyrroles; 2.2.2 Pyrrolidine Alkaloids; 2.2.2.1 Pyrrolidines; 2.2.2.2 Dipyrrolidines; 2.2.2.3 Polyhydroxypyrrolidines; 2.2.3 Indolizidine Alkaloids; 2.2.3.1 Polycyclic Indolizidines; 2.2.3.2 Polyhydroxyindolizidines; 2.2.4 Pyrrolizidine Alkaloids; 2.3 Six-membered Nitrogen Heterocycles; 2.3.1 Piperidine Alkaloids; 2.3.1.1 Piperidines; 2.3.1.2 Piperidine Carboxylic Acids 2.3.1.3 Piperidones2.3.1.4 Polyhydroxypiperidines; 2.3.2 Indolizidine Alkaloids; 2.3.3 Quinolizidine Alkaloids; 2.4 Seven-membered Nitrogen Heterocycles; 2.5 Eight-membered Nitrogen Heterocycles; 2.6 Conclusion; References; 3 Synthesis of Natural Products Containing Medium-size Oxygen Heterocycles by Ring-closing Alkene Metathesis; 3.1 Introduction; 3.2 General RCM Approaches to Medium Rings; 3.3 Laurencin; 3.4 Eunicellins/Eleutherobin; 3.5 Helianane; 3.6 Octalactin A; 3.7 Microcarpalide and the Herbarums; 3.8 Marine Ladder Toxins; 3.8.1 Ciguatoxin; 3.8.2 Brevetoxin 3.8.3 Gambierol, Gambieric Acid, Olefinic-ester Cyclizations3.9 Conclusion; Acknowledgments; References; 4 Phosphorus and Sulfur Heterocycles via Ring-closing Metathesis: Application in Natural Product Synthesis; 4.1 Introduction; 4.2 Synthesis and Reactivity of Sultones Derived from RCM; 4.3 Total Synthesis of the Originally Proposed Structure of (±)-Mycothiazole; 4.4 Synthesis and Reactivity of Phosphates from RCM; 4.5 Applications of Phosphate Tethers in the Synthesis of Dolabelide C; 4.6 Conclusion; Acknowledgment; References 5 Synthesis of Natural Products Containing Macrocycles by Alkene Ring-closing Metathesis5.1 Introduction; 5.2 Organization of the Chapter; 5.3 Macrocyclic Polyketides; 5.3.1 Resorcinylic Macrolides; 5.3.2 Salicylate Macrolides; 5.3.3 Other Antibiotic Macrolides; 5.3.4 Macrocyclic Musk; 5.3.5 Epothilones; 5.3.6 Amphidinolides; 5.3.7 Other Polyketides; 5.3.8 Natural Cyclophanes; 5.4 Terpenoids; 5.4.1 Diterpenoids; 5.4.2 Macrocyclic Lipids; 5.5 Macrocycles of Amino Acid Origin; 5.5.1 Macrolactams; 5.5.2 Cyclodepsipeptides; 5.5.3 Alkaloids; 5.6 Macrocyclic Glycolipids; 5.7 Conclusions and Outlook References |
| Record Nr. | UNINA-9910830522703321 |
| Weinheim, : Wiley-VCH, c2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Metathesis in natural product synthesis : strategies, substrates and catalysts / / edited by Janine Cossy, Stellios Arseniyadis, and Christophe Meyer ; with a foreword by Robert H. Grubbs
| Metathesis in natural product synthesis : strategies, substrates and catalysts / / edited by Janine Cossy, Stellios Arseniyadis, and Christophe Meyer ; with a foreword by Robert H. Grubbs |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2010 |
| Descrizione fisica | 1 online resource (414 p.) |
| Disciplina | 547.2 |
| Altri autori (Persone) |
CossyJanine
ArseniyadisS (Stellios) MeyerChristophe |
| Soggetto topico |
Natural products - Synthesis
Metathesis (Chemistry) |
| ISBN |
3-527-64208-0
1-283-51405-2 9786613826503 3-527-62963-7 3-527-62962-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Metathesis in Natural Product Synthesis: Strategies, Substrates and Catalysts; Contents; Foreword; Preface; List of Catalysts; List of Contributors; Abbreviations; 1 Synthesis of Natural Products Containing Medium-size Carbocycles by Ring-closing Alkene Metathesis; 1.1 Introduction; 1.2 Formation of Five-membered Carbocycles by RCM; 1.3 Formation of Six-membered Carbocycles by RCM; 1.4 Formation of Seven-membered Carbocycles by RCM; 1.5 Formation of Eight-membered Carbocycles by RCM; 1.6 Formation of Nine-membered Carbocycles by RCM; 1.7 Formation of 10-membered Carbocycles by RCM
1.8 ConclusionReferences; 2 Natural Products Containing Medium-sized Nitrogen Heterocycles Synthesized by Ring-closing Alkene Metathesis; 2.1 Introduction; 2.2 Five-membered Nitrogen Heterocycles; 2.2.1 Dihydropyrroles; 2.2.2 Pyrrolidine Alkaloids; 2.2.2.1 Pyrrolidines; 2.2.2.2 Dipyrrolidines; 2.2.2.3 Polyhydroxypyrrolidines; 2.2.3 Indolizidine Alkaloids; 2.2.3.1 Polycyclic Indolizidines; 2.2.3.2 Polyhydroxyindolizidines; 2.2.4 Pyrrolizidine Alkaloids; 2.3 Six-membered Nitrogen Heterocycles; 2.3.1 Piperidine Alkaloids; 2.3.1.1 Piperidines; 2.3.1.2 Piperidine Carboxylic Acids 2.3.1.3 Piperidones2.3.1.4 Polyhydroxypiperidines; 2.3.2 Indolizidine Alkaloids; 2.3.3 Quinolizidine Alkaloids; 2.4 Seven-membered Nitrogen Heterocycles; 2.5 Eight-membered Nitrogen Heterocycles; 2.6 Conclusion; References; 3 Synthesis of Natural Products Containing Medium-size Oxygen Heterocycles by Ring-closing Alkene Metathesis; 3.1 Introduction; 3.2 General RCM Approaches to Medium Rings; 3.3 Laurencin; 3.4 Eunicellins/Eleutherobin; 3.5 Helianane; 3.6 Octalactin A; 3.7 Microcarpalide and the Herbarums; 3.8 Marine Ladder Toxins; 3.8.1 Ciguatoxin; 3.8.2 Brevetoxin 3.8.3 Gambierol, Gambieric Acid, Olefinic-ester Cyclizations3.9 Conclusion; Acknowledgments; References; 4 Phosphorus and Sulfur Heterocycles via Ring-closing Metathesis: Application in Natural Product Synthesis; 4.1 Introduction; 4.2 Synthesis and Reactivity of Sultones Derived from RCM; 4.3 Total Synthesis of the Originally Proposed Structure of (±)-Mycothiazole; 4.4 Synthesis and Reactivity of Phosphates from RCM; 4.5 Applications of Phosphate Tethers in the Synthesis of Dolabelide C; 4.6 Conclusion; Acknowledgment; References 5 Synthesis of Natural Products Containing Macrocycles by Alkene Ring-closing Metathesis5.1 Introduction; 5.2 Organization of the Chapter; 5.3 Macrocyclic Polyketides; 5.3.1 Resorcinylic Macrolides; 5.3.2 Salicylate Macrolides; 5.3.3 Other Antibiotic Macrolides; 5.3.4 Macrocyclic Musk; 5.3.5 Epothilones; 5.3.6 Amphidinolides; 5.3.7 Other Polyketides; 5.3.8 Natural Cyclophanes; 5.4 Terpenoids; 5.4.1 Diterpenoids; 5.4.2 Macrocyclic Lipids; 5.5 Macrocycles of Amino Acid Origin; 5.5.1 Macrolactams; 5.5.2 Cyclodepsipeptides; 5.5.3 Alkaloids; 5.6 Macrocyclic Glycolipids; 5.7 Conclusions and Outlook References |
| Record Nr. | UNINA-9910877217803321 |
| Weinheim, : Wiley-VCH, c2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||