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Advances in micro-bioreactor design for organ cell studies / / edited Carl-Fredrik Mandenius
| Advances in micro-bioreactor design for organ cell studies / / edited Carl-Fredrik Mandenius |
| Pubbl/distr/stampa | Basel, Switzerland : , : MDPI - Multidisciplinary Digital Publishing Institute, , [2018] |
| Descrizione fisica | 1 online resource (vii, 157 pages) : illustrations |
| Disciplina | 660.6 |
| Soggetto topico | Bioreactors |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674373603321 |
| Basel, Switzerland : , : MDPI - Multidisciplinary Digital Publishing Institute, , [2018] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Bioreactors : design, operation and novel applications / / edited by Carl-Fredrik Mandenius
| Bioreactors : design, operation and novel applications / / edited by Carl-Fredrik Mandenius |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2016] |
| Descrizione fisica | 1 online resource (603 p.) |
| Soggetto topico | Bioreactors - Design and construction |
| ISBN |
3-527-68338-0
1-5231-1519-X 3-527-68336-4 3-527-68337-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Title Page; Copyright; Table of Contents; Preface; List of Contributors; Chapter 1: Challenges for Bioreactor Design and Operation; 1.1 Introduction; 1.2 Biotechnology Milestones with Implications on Bioreactor Design; 1.3 General Features of Bioreactor Design; 1.4 Recent Trends in Designing and Operating Bioreactors; 1.5 The Systems Biology Approach; 1.6 Using Conceptual Design Methodology; 1.7 An Outlook on Challenges for Bioreactor Design and Operation; References; Chapter 2: Design and Operation of Microbioreactor Systems for Screening and Process Development; 2.1 Introduction
2.2 Key Engineering Parameters and Properties in Microbioreactor Design and Operation2.3 Design of Novel Stirred and Bubble Aerated Microbioreactors; 2.4 Robotics for Microbioreactors; 2.5 Fed-Batch and Continuous Operation of Microbioreactors; 2.6 Monitoring and Control of Microbioreactors; 2.7 Conclusion; References; Chapter 3: Bioreactors on a Chip; 3.1 Introduction; 3.2 Advantages of Microsystems; 3.3 Scaling Down the Bioreactor to the Microfluidic Format; 3.4 Microfabrication Methods for Bioreactors-On-A-Chip; 3.5 Fabrication Materials 3.6 Integrated Sensors for Key Bioreactor Parameters3.7 Model Organisms Applied to BRoCs; 3.8 Applications of Microfluidic Bioreactor Chip; 3.9 Scale Up; 3.10 Conclusion; References; Chapter 4: Scalable Manufacture for Cell Therapy Needs; 4.1 Introduction; 4.2 Requirements for Cell Therapy; 4.3 Stem Cell Types and Products; 4.4 Paradigms in Cell Therapy Manufacture; 4.5 Cell Therapy Manufacturing Platforms; 4.6 Microcarriers and Stirred-Tank Bioreactors; 4.7 Future Trends for Microcarrier Culture; 4.8 Preservation of Cell Therapy Products; 4.9 Conclusions; References Chapter 5: Artificial Liver Bioreactor Design5.1 Need for Innovative Liver Therapies; 5.2 Requirements to Liver Support Systems; 5.3 Bioreactor Technologies Used in Clinical Trials; 5.4 Optimization of Bioartificial Liver Bioreactor Designs; 5.5 Improvement of Cell Biology in Bioartificial Livers; 5.6 Bioreactors Enabling Cell Production for Transplantation; 5.7 Cell Sources for Bioartificial Liver Bioreactors; 5.8 Outlook; References; Chapter 6: Bioreactors for Expansion of Pluripotent Stem Cells and Their Differentiation to Cardiac Cells; 6.1 Introduction 6.2 Culture Technologies for Pluripotent Stem Cell Expansion6.3 3D Suspension Culture; 6.4 Autologous Versus Allogeneic Cell Therapies: Practical and Economic Considerations for hPSC Processing; 6.5 Upscaling hPSC Cardiomyogenic Differentiation in Bioreactors; 6.6 Conclusion; References; Chapter 7: Culturing Entrapped Stem Cells in Continuous Bioreactors; 7.1 Introduction; 7.2 Materials Used in Stem Cell Entrapment; 7.3 Synthetic Materials; 7.4 Natural Materials; 7.5 Manufacturing and Regulatory Constraints; 7.6 Mass Transfer in the Entrapment Material 7.7 Continuous Bioreactors for Entrapped Stem Cell Culture |
| Record Nr. | UNINA-9910136413703321 |
| Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2016] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Bioreactors : design, operation and novel applications / / edited by Carl-Fredrik Mandenius
| Bioreactors : design, operation and novel applications / / edited by Carl-Fredrik Mandenius |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2016] |
| Descrizione fisica | 1 online resource (603 p.) |
| Soggetto topico | Bioreactors - Design and construction |
| ISBN |
3-527-68338-0
1-5231-1519-X 3-527-68336-4 3-527-68337-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Title Page; Copyright; Table of Contents; Preface; List of Contributors; Chapter 1: Challenges for Bioreactor Design and Operation; 1.1 Introduction; 1.2 Biotechnology Milestones with Implications on Bioreactor Design; 1.3 General Features of Bioreactor Design; 1.4 Recent Trends in Designing and Operating Bioreactors; 1.5 The Systems Biology Approach; 1.6 Using Conceptual Design Methodology; 1.7 An Outlook on Challenges for Bioreactor Design and Operation; References; Chapter 2: Design and Operation of Microbioreactor Systems for Screening and Process Development; 2.1 Introduction
2.2 Key Engineering Parameters and Properties in Microbioreactor Design and Operation2.3 Design of Novel Stirred and Bubble Aerated Microbioreactors; 2.4 Robotics for Microbioreactors; 2.5 Fed-Batch and Continuous Operation of Microbioreactors; 2.6 Monitoring and Control of Microbioreactors; 2.7 Conclusion; References; Chapter 3: Bioreactors on a Chip; 3.1 Introduction; 3.2 Advantages of Microsystems; 3.3 Scaling Down the Bioreactor to the Microfluidic Format; 3.4 Microfabrication Methods for Bioreactors-On-A-Chip; 3.5 Fabrication Materials 3.6 Integrated Sensors for Key Bioreactor Parameters3.7 Model Organisms Applied to BRoCs; 3.8 Applications of Microfluidic Bioreactor Chip; 3.9 Scale Up; 3.10 Conclusion; References; Chapter 4: Scalable Manufacture for Cell Therapy Needs; 4.1 Introduction; 4.2 Requirements for Cell Therapy; 4.3 Stem Cell Types and Products; 4.4 Paradigms in Cell Therapy Manufacture; 4.5 Cell Therapy Manufacturing Platforms; 4.6 Microcarriers and Stirred-Tank Bioreactors; 4.7 Future Trends for Microcarrier Culture; 4.8 Preservation of Cell Therapy Products; 4.9 Conclusions; References Chapter 5: Artificial Liver Bioreactor Design5.1 Need for Innovative Liver Therapies; 5.2 Requirements to Liver Support Systems; 5.3 Bioreactor Technologies Used in Clinical Trials; 5.4 Optimization of Bioartificial Liver Bioreactor Designs; 5.5 Improvement of Cell Biology in Bioartificial Livers; 5.6 Bioreactors Enabling Cell Production for Transplantation; 5.7 Cell Sources for Bioartificial Liver Bioreactors; 5.8 Outlook; References; Chapter 6: Bioreactors for Expansion of Pluripotent Stem Cells and Their Differentiation to Cardiac Cells; 6.1 Introduction 6.2 Culture Technologies for Pluripotent Stem Cell Expansion6.3 3D Suspension Culture; 6.4 Autologous Versus Allogeneic Cell Therapies: Practical and Economic Considerations for hPSC Processing; 6.5 Upscaling hPSC Cardiomyogenic Differentiation in Bioreactors; 6.6 Conclusion; References; Chapter 7: Culturing Entrapped Stem Cells in Continuous Bioreactors; 7.1 Introduction; 7.2 Materials Used in Stem Cell Entrapment; 7.3 Synthetic Materials; 7.4 Natural Materials; 7.5 Manufacturing and Regulatory Constraints; 7.6 Mass Transfer in the Entrapment Material 7.7 Continuous Bioreactors for Entrapped Stem Cell Culture |
| Record Nr. | UNINA-9910816353403321 |
| Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2016] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Measurement Technologies for up- and Downstream Bioprocessing
| Measurement Technologies for up- and Downstream Bioprocessing |
| Autore | Mandenius Carl-Fredrik |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (160 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
AAV-adeno-associated virus
amino acids at-line measurement automated sampling bioprocess carbon dioxide cation exchange chromatography cell culture cell culture monitoring cell viability CHO chromatogram fingerprinting dielectric spectroscopy digital holographic microscopy enzyme electrode filamentous fungi gene therapy high-throughput HPLC-SEC IgG titer in-line monitoring insect cell-baculovirus lactate biosensor mammalian cell culture monitoring n/a nanoplasmonic off-gas measurement off-line monitoring on-line PAT pCO2 Penicillium chrysogenum pH prediction process analytical technology Raman spectroscopy real-time reference scale-down technologies screen-printing Trichoderma reesei Rut-C30 vitamins |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557333203321 |
Mandenius Carl-Fredrik
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Measurement, Monitoring, Modelling and Control of Bioprocesses / / edited by Carl-Fredrik Mandenius, Nigel J Titchener-Hooker
| Measurement, Monitoring, Modelling and Control of Bioprocesses / / edited by Carl-Fredrik Mandenius, Nigel J Titchener-Hooker |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013 |
| Descrizione fisica | 1 online resource (X, 285 p. 74 illus., 53 illus. in color.) |
| Disciplina | 660.6 |
| Collana | Advances in Biochemical Engineering/Biotechnology |
| Soggetto topico |
Biotechnology
Quality control Reliability Industrial safety Chemical engineering Quality Control, Reliability, Safety and Risk Industrial Chemistry/Chemical Engineering |
| ISBN | 3-642-36838-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Automated Measurement and Monitoring of Bioprocesses: Key Elements of the M3C Strategy, by Bernhard Sonnleitner -- Automatic Control of Bioprocesses, by Marc Stanke, Bernd Hitzmann -- An Advanced Monitoring Platform for Rational Design of Recombinant Processes, by G. Striedner, K. Bayer -- Modelling Approaches for Bio-Manufacturing Operations, by Sunil Chhatre -- Extreme Scale-Down Approaches for Rapid Chromatography Column Design and Scale-Up During Bioprocess Development, by Sunil Chhatre -- Applying Mechanistic Models in Bioprocess Development, by Rita Lencastre Fernandes, Vijaya Krishna Bodla, Magnus Carlquist, Anna-Lena Heins, Anna Eliasson Lantz, Gürkan Sin and Krist V. Gernaey -- Multivariate Data Analysis for Advancing the Interpretation of Bioprocess -- Measurement and Monitoring Data, by Jarka Glassey -- Design of Pathway-Level Bioprocess Monitoring and Control Strategies Supported by Metabolic Networks, by Inês A. Isidro, Ana R. Ferreira, João J. Clemente, António E. Cunha, João M. L. Dias, Rui Oliveira -- Knowledge Management and Process Monitoring of Pharmaceutical Processes in the Quality by Design Paradigm, by Anurag S Rathore, Anshuman Bansal, Jaspinder Hans -- The Choice of Suitable Online Analytical Techniques and Data Processing for Monitoring of Bioprocesses, by Ian Marison, Siobhán Hennessy, Róisín Foley, Moira Schuler, Senthilkumar Sivaprakasam, Brian Freeland. |
| Record Nr. | UNINA-9910437821403321 |
| Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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