Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Advances in Automated Driving Systems
| Advances in Automated Driving Systems |
| Autore | Eichberger Arno |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (294 p.) |
| Soggetto topico |
History of engineering & technology
Technology: general issues |
| Soggetto non controllato |
acceptance
adaptive control adaptive cruise control ADAS advanced driver assistant systems (ADAS) automated driving automated driving (AD) automated driving systems automation autonomous conflict management autonomous drifting autonomous vehicles calibration method connected and automated vehicle convolutional neural network cooperative perception decomposition deep learning digital twin driver assistance system driver drowsiness driving school driving simulator ECG signal edge cloud expression of trust fault tree analysis framework development ground truth heart rate variability illumination informed machine learning instance segmentation inverse gamma correction ITS lane detection Mask R-CNN model predictive control (MPC) modular safety approval modular testing multi-layer perceptron n/a NASA TLX pedestrian custom dataset physical perception model physics-guided reinforcement learning radar sensor reference measurement safety safety validation scenario-based testing sensor fusion simulation simulation and modeling simulation and modelling simulator case study software framework state prediction successive linearization system usability scale throttle prediction traffic evaluation traffic sign recognition system traffic signs transfer learning U-Space UAV UGV UTM varying road surfaces vehicle dynamics vehicle motion control virtual sensor model virtual test and validation virtual validation wavelet scalogram wheel loaders |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580214003321 |
Eichberger Arno
|
||
| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Anesthesia for Oncological Surgery / / edited by Jeffrey Huang, Jiapeng Huang, Henry Liu
| Anesthesia for Oncological Surgery / / edited by Jeffrey Huang, Jiapeng Huang, Henry Liu |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (459 pages) |
| Disciplina | 617.96 |
| Collana | Medicine Series |
| Soggetto topico |
Anesthesiology
Oncology Surgery Cancer Cancers |
| ISBN | 3-031-50977-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Oncogenesis: what is new? -- Epidemiology of cancer -- Immunomodulation and cancer -- Cancer-targeted molecular therapy -- Car-T therapy -- The Surgeon – Anesthesia professional Relationship -- Anesthesia techniques and cancer recurrence -- Prehabilitation -- Preoperative evaluation and preparations for oncological surgery -- ERAS/Surgical Home of oncological patients -- Blood Management for Oncological Surgery -- Acute Pain Service for oncological surgery -- Chronic Pain Clinic in Cancer Center and -- Oncological services -- Non pharmaceutics therapy for oncological patients -- Craniotomy for meningioma -- Craniotomy for glioma -- Craniotomy for brain stem tumor -- Awake Craniectomy -- Resection of pituitary gland tumor -- Posterior Fossa Tumor Resection -- Cervical spine cancer surgery -- Thoracic spine malignancy surgery -- Lumbar spine surgery -- Surgery for spinal cord tumor -- Oral cancer, Tongue and tonsil cancer surgery -- Parotid gland cancer Surgery -- Laryngeal cancer surgery -- Tracheostomy in cancer patients -- Thyroid /parathyroid cancer surgery -- Neck dissection and reconstruction -- Lobectomy for lung cancer -- Surgery for pleural malignancies -- Surgery for cardiac malignancies -- Surgery for mediastinal cancer -- Surgery for tracheal cancer -- Surgery for mainstem bronchial cancer -- Esophageal cancer surgery -- Gastric cancer surgery -- Liver cancer surgery -- Pancreatic cancer -- Colon/rectal cancer surgery -- HIPEC -- Biliary system cancer surgery -- Appendiceal cancer surgery -- Retroperitoneal tumor surgery -- Renal cancer surgery -- Bladder cancer surgery -- Prostate cancer surgery -- Urethral cancer surgery -- Testicular/penile cancer surgery -- Surgery for adrenal tumor -- Surgery for carcinoid syndrome -- Neuroendocrine/CREST cancer surgery -- Ovarian cancer surgery -- Uterine cancer surgery -- Cervical cancer surgery -- Perineal cancer surgery -- Surgery for bone sarcoma -- Surgery for rhabdomyosarcoma -- Surgery for breast cancer -- Cutaneous cancer surgery -- Nephroblastoma -- Wilms tumor and Hepatoblastoma -- Pheochromocytoma -- Medulloblastoma -- Pilocytic Astrocytoma -- Intra-arterial therapy for primary and secondary liver cancer -- Percutaneous Ablative techniques for liver and kidney cancer -- Interventional diagnostic and therapeutic procedures in surgical oncology -- Intensive care of cancer patients -- Palliative care of cancer patients -- Hospice and Palliative care of cancer patients . |
| Record Nr. | UNINA-9910842296303321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Blood substitutes and oxygen biotherapeutics / / edited by Henry Liu, Alan D. Kaye, and Jonathan S. Jahr
| Blood substitutes and oxygen biotherapeutics / / edited by Henry Liu, Alan D. Kaye, and Jonathan S. Jahr |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2022] |
| Descrizione fisica | 1 online resource (441 pages) |
| Disciplina | 617.96 |
| Soggetto topico | Anesthesiology |
| ISBN | 3-030-95975-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Foreword -- Blood Substitutes and Oxygen Biotherapeutics -- Is the Final Destination in the Long, Winding, Bumpy Road Finally in Sight? -- Contents -- Contributors -- Part I: Transfusion: Science and Practice -- 1: Erythrocyte Transfusion: Brief History and Current Practice -- Introduction -- Milestones in Erythrocyte Transfusion -- Karl Landsteiner and Discovery of Major Blood Groups -- The Early Years of Transfusion: The First Milestone -- Karl Landsteiner -- Balancing the Risks and Benefits of Anemia and Transfusion: The Second Milestone -- The Risks of Anemia -- The Target Organs of Anemia-Induced Injury -- Benefits and Risks of Erythrocyte Transfusion -- The Benefits of Transfusion -- The Risks of Transfusion -- Transfusion Reactions -- Transfusion Transmitted Infectious (TTI) Pathogens -- Transfusion-Attributable Adverse Outcomes -- Transfusion Avoidance and Blood Conservation -- The Search for an Objective Transfusion "Trigger" -- The Transfusion Requirements in Critical Care (TRICC) Study -- Restrictive vs Liberal Transfusion in Cardiac Surgery -- Patient Blood Management -- Summary and Conclusions -- References -- 2: Oxygen and ATP: the Energy Economy of the Cell -- Introduction -- Oxygen -- Adenosine Triphosphate -- ATP Production: An Overview -- Oxygen Utilization: An Overview -- The Cell's Energy Economy -- Aerobic Respiration -- Glycolysis -- In Summary -- Exceptional Case: Glycolysis in the Erythrocyte -- The Krebs Cycle -- Overview -- Some Details -- The Electron Transport Chain, Oxidative Phosphorylation -- Mitochondria -- Friend or Foe? -- The Energy Economy of Vital Organs -- The Heart -- The Brain -- Neurovascular Coupling -- Neurometabolic Coupling -- The Kidney -- The Liver -- Oxygen Sensing -- The Carotid Body Chemoreceptors -- HIF Mediators -- Cardiovascular System and Oxygen Supply Integration: The Role of NO.
In Summary -- "Bad" Oxygen Species -- Summary and Conclusions -- References -- 3: Physiological Functions of Blood -- Introduction -- Hematopoiesis -- Basic Physiology of the Components of Blood -- Transport of Oxygen and Carbon Dioxide -- Transport of Hormones, Nutrients and Metabolic Waste -- Hemostasis and Coagulation -- Immune System -- Acid-Base Regulation -- Thermoregulation -- Regulation of Body Fluids -- Conclusion -- References -- 4: Hemoglobin: Physiology and Hemoglobinopathy -- Introduction -- Hemoglobin and Oxygen Binding Regulation -- Oxygen Binding -- 2,3-DPG -- Hemoglobinopathies -- Thalassemia Syndromes -- Sickle Cell Disease -- Summary -- References -- 5: The Global Burden of Anemia -- Introduction -- Anemia Development and Classification -- Health and Societal Implications of Anemia -- Summary -- References -- 6: Blood Component Therapy: The History, Efficacy, and Adverse Effects in Clinical Practice -- Introduction -- Red Cell Components -- Red Blood Cell Concentrates -- Collection and Processing -- Principles of Preservation -- RBC Storage Lesions -- Metabolic Impairment -- Oxidative Injury -- Membrane Asymmetry -- Vesiculation -- Decreased Deformability -- Physiological Considerations -- Hemolysis -- Oxygen Delivery -- Hemostasis and Thrombosis -- Immunomodulation -- Clinical Outcomes -- Component Therapy: All Things "Yellow" -- Plasma Transfusions -- The Origin of Plasmapheresis Leading to Fresh Frozen Plasma -- Cryoprecipitate -- Platelets -- Platelet Activation and Adherence -- References -- 7: Allogeneic Blood Transfusion: Complications and Side Effects -- Introduction -- Infectious Complications -- Human Immunodeficiency Virus -- Hepatitis C Virus -- Hepatitis B Virus -- Septic Transfusion Reactions -- Immune-Mediated Complications -- Hemolytic Transfusion Reaction -- Allergic/Anaphylactic Complications. Allergic Transfusion Reactions -- Anaphylactic Transfusion Reactions -- Febrile Transfusion Reactions -- Cardiac and Pulmonary Complications -- Transfusion Associated Circulatory Overload -- Transfusion Associated Acute Lung Injury -- Conclusion -- References -- 8: The Effects of Hemoglobin-Based Oxygen Carriers (HBOC) on the Microcirculation -- Background -- Effects on the Microcirculation: A Hamster Skinfold Study -- Effects on the Microcirculation: A Canine Bulbar Conjunctiva Study -- Discussion -- References -- 9: Nitric Oxide and Hemoglobin: Physiological Implications -- Introduction -- Nitric Oxide Cardiovascular Effects -- Nitric Oxide Vascular Effects -- Nitric Oxide and Hemodynamic Regulations -- Hemoglobin (Hb) -- Interactions Between NO and Hemoglobin -- Nitrosyl Hemoglobin -- NO Bioactivity and Hemoglobin -- NO, Red Cell Biology and Blood Substitutes -- NO Scavenging -- Conclusion -- References -- 10: A Brief History of the Development of Nanobiotechnology-Based Blood Substitutes -- Introduction -- Hemolysate and Stroma Free Hemoglobin -- Early Basic Research on Nanobiotechnology Based RBC Substitute -- Polyhemoglobin Based on Nanobiotechnology -- First Generation Hemoglobin Based Oxygen Carriers (HBOCs) -- Four General Types of HBOCs -- Development During the HIV Contaminated Donor Blood Crisis -- Intramolecularly Crosslinked Hemoglobin -- Polyhemoglobin -- Glutaraldehyde Crosslinked Human PolyHb -- Glutaraldehyde Crosslinked Bovine PolyHb -- Conjugated Hemoglobin -- Nitric Oxide -- Inhalation of Nitric Oxide to Prevent Vasoconstriction -- Pyridoxalated Hemoglobin Polyoxyethylene as NO Scavenger in Distributive Shock -- Other Sources of Hemoglobin -- Bioengineering and Recombinant Methods -- Nanobiotechnology Based Oxygen Carriers with Antioxidant Functions -- Introduction -- PolyHb-CAT-SOD -- Convalently Binding of Nitroxides to PEG-Hb. Dual Carbon Monoxide and Oxygen Delivery Agent -- Vitamin C as Antioxidant -- Other Approaches -- Preservation for Transplant Organ -- Early Basic Research -- Light's Group -- Zal's Group -- Nanobiotechnology Based Oxygen Carriers with Enhancement of All Three RBC Functions -- Introduction -- Polyhemoglobin with Enhanced Catalase-Superoxide Dismutase-Carbonic Anhydrase -- Nanodimension Artificial Red Blood Cells -- Early Artificial Red Blood Cells -- Bilayer Lipid Membrane Nano Artificial RBC (Fig. 10.6) -- Nano-Dimension Biodegradable Polymeric Artificial Cells -- Variations in the Membrane and Configurations of Nano Artificial RBC -- Nonfunctional or Functional Membrane (Fig. 10.8) -- Other Areas -- Nanobiotechnology Based Oxygen Carrier with Platelet Function -- Nanobiotechnology Based Oxygen Carriers with Cancer Suppression Functions -- Stem Cells -- Future Development -- Summary Discussions -- What We Have Learned from Past History -- What Needs to Be Done -- References -- Part II: Pharmacology and Physiology of Oxygen Therapeutics -- 11: Classifications of Blood Substitutes -- Introduction -- Blood Composition -- Classification of Blood Substitutes -- Classification Based on the Blood Components -- Red Blood Cell Substitutes -- White Blood Cell (Leukocyte) Substitutes -- Platelet Substitutes -- Plasma Substitutes -- Classification of Erythrocyte Substitutes -- Hemoglobin-Based Oxygen Carriers -- Perfluorocarbon-Based Oxygen Carriers (PFBOC) -- Genetic Engineered Recombinant Hemoglobin -- Artificial and Cultured Red Blood Cells -- Erythrocyte Substitutes Classification Based on Hemoglobin Sources -- Erythrocyte Substitutes: Classification Based on RBC Membrane -- Erythrocyte Substitutes: Classification Based on Organic Molecule -- Erythrocyte Substitutes: Classification Based on Synthetic or Natural Molecule -- Ideal Erythrocyte Substitutes. Potential Indications for Blood Substitutes -- Summary -- References -- 12: Hemoglobin-Based Oxygen Carriers: Brief History, Pharmacology and Design Strategies, Review of the Major Products in Clinical Trials, On-Going Studies, and Coagulation Concerns -- Introduction -- Transfusion Medicine -- History of Hemoglobin-Based Oxygen Carriers -- How HBOCs Are Made -- Stroma Free Hemoglobin -- α-α Cross Linked Hb -- Glutaraldehyde Polymerized Hbs -- Recombinant HBOC -- Zero-Linked HBOCs -- Pegylated HBOCs -- Invertebrate Hb -- Pharmacology and Physiology of HBOCs -- Development of HBOCs -- Development of αα-Hb and HemAssist -- Development of Hemolink -- Development of Polyheme -- Development of Hemoximer -- Development of Hemopure and Summary/Discussion of Pivotal HEM-0115 Trial -- Adverse Events of Particular Interest -- Recent Clinical Trials on Hemopure -- Development of Third Generation HBOCs -- Coagulation and HBOCs -- Introduction -- Single Site Clinical Study of Hemopure on Platelet Function -- Summary of Hemopure -- Summary and Moving Forward -- References -- 13: Complications of HBOCs Including Clinical Safety Issues -- Introduction -- Criticism of the Natanson et al. Meta-Analysis -- Safety Aspects of Specific HBOCs -- HemAssist -- Optro -- Hemolink -- Polyheme -- MP40x-Hemospan ("3rd Generation") -- Hemopure (Biopure, OPK Pharma, HBO2 Therapeutics) -- Sanguinate (Prolong Pharmaceuticals) -- Adverse Events -- Conclusion -- References -- 14: On the Oxidative Toxicity of Hemoglobin -- Red Blood Cell Oxidation Reactions in Health and Disease: What Have We Learned? -- Oxidation of Hemoglobin and Cytosolic Antioxidative Proteins -- The Role of Red Cell Band 3 in Hemoglobin Oxidation -- Hemoglobin-Driven Oxidation Reactions Promote Microparticles Formation -- Role of β Cysteine 93 in Oxidative Stability of Hemoglobin. Genetically and Chemically Modified HBOCs: The Impact of Molecular Modifications. |
| Record Nr. | UNINA-9910586580103321 |
| Cham, Switzerland : , : Springer, , [2022] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||