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Biocatalysis for the pharmaceutical industry : discovery, development, and manufacturing / / Junhua Tao, Guoqiang Lin, Andreas Liese
| Biocatalysis for the pharmaceutical industry : discovery, development, and manufacturing / / Junhua Tao, Guoqiang Lin, Andreas Liese |
| Autore | Tao Junhua |
| Pubbl/distr/stampa | Singapore ; ; Hoboken, : Wiley, 2009 |
| Descrizione fisica | 1 online resource (x, 324 pages) : illustrations |
| Disciplina | 615.19 |
| Altri autori (Persone) |
LinGuoqiang
LieseA (Andreas) |
| Soggetto topico |
Pharmaceutical biotechnology
Enzymes - Biotechnology |
| ISBN |
1-282-38209-8
9786612382093 0-470-82316-X 0-470-82315-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
1. Enzymes and Their Synthetic Applications: An Overview -- 2. Expression Hosts for Enzyme Discovery and Production -- 3. Directed Enzyme Evolution and High-Throughput Screening -- 4. Applications of Reaction Engineering to Industrial Biotransformations -- 5. Chiral Synthesis of Pharmaceutical Intermediates Using Oxynitrilases -- 6. Expanding the Scope of Aldolases as Tools for Organic Synthesis -- 7. Synthetic Applications of Ketoreductases and Alcohol Oxidases --
8. Applications of Nitrile Hydratases and Nitrilases -- 9. Biosynthesis of Drug Metabolites -- 10. Application of Whole-Cell Biotransformation in the Pharmaceutical Industry -- 11. Combinatorial Biosynthesis of Pharmaceutical Natural Products -- 12. Metabolic Engineering for the Development and Manufacturing of Pharmaceuticals -- 13. Multimodular Synthases and Supporting Enzymes for Chemical Production -- 14. Green Chemistry with Biocatalysis for Production of Pharmaceuticals. |
| Record Nr. | UNINA-9910139778503321 |
Tao Junhua
|
||
| Singapore ; ; Hoboken, : Wiley, 2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biocatalysis for the pharmaceutical industry : discovery, development, and manufacturing / / Junhua Tao, Guoqiang Lin, Andreas Liese
| Biocatalysis for the pharmaceutical industry : discovery, development, and manufacturing / / Junhua Tao, Guoqiang Lin, Andreas Liese |
| Autore | Tao Junhua |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Singapore ; ; Hoboken, : Wiley, c2009 |
| Descrizione fisica | 1 online resource (x, 324 pages) : illustrations |
| Disciplina | 615.19 |
| Altri autori (Persone) |
LinGuoqiang
LieseA (Andreas) |
| Soggetto topico |
Pharmaceutical biotechnology
Enzymes - Biotechnology |
| ISBN |
9786612382093
9781282382091 1282382098 9780470823163 047082316X 9780470823156 0470823151 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
1. Enzymes and Their Synthetic Applications: An Overview -- 2. Expression Hosts for Enzyme Discovery and Production -- 3. Directed Enzyme Evolution and High-Throughput Screening -- 4. Applications of Reaction Engineering to Industrial Biotransformations -- 5. Chiral Synthesis of Pharmaceutical Intermediates Using Oxynitrilases -- 6. Expanding the Scope of Aldolases as Tools for Organic Synthesis -- 7. Synthetic Applications of Ketoreductases and Alcohol Oxidases --
8. Applications of Nitrile Hydratases and Nitrilases -- 9. Biosynthesis of Drug Metabolites -- 10. Application of Whole-Cell Biotransformation in the Pharmaceutical Industry -- 11. Combinatorial Biosynthesis of Pharmaceutical Natural Products -- 12. Metabolic Engineering for the Development and Manufacturing of Pharmaceuticals -- 13. Multimodular Synthases and Supporting Enzymes for Chemical Production -- 14. Green Chemistry with Biocatalysis for Production of Pharmaceuticals. |
| Record Nr. | UNINA-9910807350603321 |
|
Tao Junhua
|
||
| Singapore ; ; Hoboken, : Wiley, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Industrial biotransformations [[electronic resource] /] / edited by Andreas Liese, Karsten Seelbach, Christian Wandrey
| Industrial biotransformations [[electronic resource] /] / edited by Andreas Liese, Karsten Seelbach, Christian Wandrey |
| Edizione | [2nd completely rev and extened ed.] |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH |
| Descrizione fisica | 1 online resource (572 p.) |
| Disciplina | 660.63 |
| Altri autori (Persone) |
LieseA (Andreas)
SeelbachK (Karsten) WandreyChristian <1943-> |
| Soggetto topico |
Biotransformation (Metabolism)
Biochemical engineering |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-72336-X
9786610723362 3-527-60818-4 3-527-60790-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Industrial Biotransformations; Contents; Preface to the first edition; Preface to the second edition; List of Contributors; 1 History of Industrial Biotransformations - Dreams and Realities; 1.1 From the "Flower of Vinegar" to Recombinant E. Coli - The History of Microbial Biotransformations; 1.2 From Gastric Juice to SweetzymeT - The History of Enzymatic Biotransformations; 1.3 From Wine Bottle to a State-of-the-Art Facility - The History of Biochemical Engineering; 1.4 Advantages of Biotransformations Over Classical Chemistry Enzymes are proteins, things of beauty and a joy forever [40]
2 The Enzyme Classification2.1 Enzyme Nomenclature; 2.2 Enzyme Classes; 2.2.1 EC 1 Oxidoreductases; 2.2.2 EC 2 Transferases; 2.2.3 EC 3 Hydrolases; 2.2.4 EC 4 Lyases; 2.2.5 EC 5 Isomerases; 2.2.6 EC 6 Ligases; 3 Retrosynthetic Biocatalysis; 3.1 Alkanes; 3.2 Alkenes; 3.3 Amines; 3.4 Alcohols; 3.5 Aldehydes; 3.6 Ketones; 3.7 Epoxides; 3.8 Diols; 3.9 Carboxylic Acids; 3.10 Esters; 3.11 Amides; 3.12 Imines; 3.13 Amino Acids; 3.14 Hydroxy Acids; 3.15 α-Hydroxy Ketones; 3.16 β-Hydroxy Aldehydes, Ketones or Carboxylic Acids; 3.17 Cyanohydrins, Hemithioacetals and Hemiaminals 3.18 Sulfoxides and Sulfones3.19 Halides; 3.20 Aromatics (Ring Functionalization); 3.21 Cyclic Compounds; 3.22 Carbohydrates; 3.23 Peroxides; 3.24 Isomers; 3.25 Examples of Retrosynthetic Biotransformations; 3.25.1 Example 1; 3.25.2 Example 2; 4 Optimization of Industrial Enzymes by Molecular Engineering; 4.1 Introduction; 4.2 Learning from Nature; 4.3 Enzyme Production Using Bacterial Expression Hosts; 4.4 Improvements to Enzymes by Molecular Engineering Techniques; 4.4.1 Rational Enzyme Design; 4.4.2 Directed Evolution; 4.4.3 Random Mutagenesis Methods 4.5 Identification of Improved Enzyme Variants4.6 Conclusions and Future Prospects; 5 Basics of Bioreaction Engineering; 5.1 Definitions; 5.1.1 Process Definitions; 5.1.2 Definitions of Unit Operations; 5.2 Biocatalyst Kinetics; 5.2.1 Types of Biocatalysts; 5.2.2 Enzyme Structure; 5.2.3 Kinetics; 5.3 Basic Reactor Types and their Modes of Operation; 5.3.1 Mass and Energy Balances; 5.4 Biocatalyst Recycling and Recovery; 5.4.1 Entrapment; 5.4.2 Cross-linking; 5.4.3 Covalent Binding; 5.4.4 Membrane Filtration; 5.5 Reaction Parameters; 5.6 Scale-up of Bioreactors 5.7 Recent Developments and Trends6 Processes; Oxireductases EC 1; Transferases EC 2; Hydrolases EC 3; Lyases EC 4; Isomerases EC 5; 7 Quantitative Analysis of Industrial Biotransformations; Index; Index of enzyme name; Index of strain; Index of company; Index of starting material; Index of product |
| Record Nr. | UNINA-9910144562603321 |
| Weinheim, : Wiley-VCH | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Industrial biotransformations [[electronic resource] /] / edited by Andreas Liese, Karsten Seelbach, Christian Wandrey
| Industrial biotransformations [[electronic resource] /] / edited by Andreas Liese, Karsten Seelbach, Christian Wandrey |
| Edizione | [2nd completely rev and extened ed.] |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH |
| Descrizione fisica | 1 online resource (572 p.) |
| Disciplina | 660.63 |
| Altri autori (Persone) |
LieseA (Andreas)
SeelbachK (Karsten) WandreyChristian <1943-> |
| Soggetto topico |
Biotransformation (Metabolism)
Biochemical engineering |
| ISBN |
1-280-72336-X
9786610723362 3-527-60818-4 3-527-60790-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Industrial Biotransformations; Contents; Preface to the first edition; Preface to the second edition; List of Contributors; 1 History of Industrial Biotransformations - Dreams and Realities; 1.1 From the "Flower of Vinegar" to Recombinant E. Coli - The History of Microbial Biotransformations; 1.2 From Gastric Juice to SweetzymeT - The History of Enzymatic Biotransformations; 1.3 From Wine Bottle to a State-of-the-Art Facility - The History of Biochemical Engineering; 1.4 Advantages of Biotransformations Over Classical Chemistry Enzymes are proteins, things of beauty and a joy forever [40]
2 The Enzyme Classification2.1 Enzyme Nomenclature; 2.2 Enzyme Classes; 2.2.1 EC 1 Oxidoreductases; 2.2.2 EC 2 Transferases; 2.2.3 EC 3 Hydrolases; 2.2.4 EC 4 Lyases; 2.2.5 EC 5 Isomerases; 2.2.6 EC 6 Ligases; 3 Retrosynthetic Biocatalysis; 3.1 Alkanes; 3.2 Alkenes; 3.3 Amines; 3.4 Alcohols; 3.5 Aldehydes; 3.6 Ketones; 3.7 Epoxides; 3.8 Diols; 3.9 Carboxylic Acids; 3.10 Esters; 3.11 Amides; 3.12 Imines; 3.13 Amino Acids; 3.14 Hydroxy Acids; 3.15 α-Hydroxy Ketones; 3.16 β-Hydroxy Aldehydes, Ketones or Carboxylic Acids; 3.17 Cyanohydrins, Hemithioacetals and Hemiaminals 3.18 Sulfoxides and Sulfones3.19 Halides; 3.20 Aromatics (Ring Functionalization); 3.21 Cyclic Compounds; 3.22 Carbohydrates; 3.23 Peroxides; 3.24 Isomers; 3.25 Examples of Retrosynthetic Biotransformations; 3.25.1 Example 1; 3.25.2 Example 2; 4 Optimization of Industrial Enzymes by Molecular Engineering; 4.1 Introduction; 4.2 Learning from Nature; 4.3 Enzyme Production Using Bacterial Expression Hosts; 4.4 Improvements to Enzymes by Molecular Engineering Techniques; 4.4.1 Rational Enzyme Design; 4.4.2 Directed Evolution; 4.4.3 Random Mutagenesis Methods 4.5 Identification of Improved Enzyme Variants4.6 Conclusions and Future Prospects; 5 Basics of Bioreaction Engineering; 5.1 Definitions; 5.1.1 Process Definitions; 5.1.2 Definitions of Unit Operations; 5.2 Biocatalyst Kinetics; 5.2.1 Types of Biocatalysts; 5.2.2 Enzyme Structure; 5.2.3 Kinetics; 5.3 Basic Reactor Types and their Modes of Operation; 5.3.1 Mass and Energy Balances; 5.4 Biocatalyst Recycling and Recovery; 5.4.1 Entrapment; 5.4.2 Cross-linking; 5.4.3 Covalent Binding; 5.4.4 Membrane Filtration; 5.5 Reaction Parameters; 5.6 Scale-up of Bioreactors 5.7 Recent Developments and Trends6 Processes; Oxireductases EC 1; Transferases EC 2; Hydrolases EC 3; Lyases EC 4; Isomerases EC 5; 7 Quantitative Analysis of Industrial Biotransformations; Index; Index of enzyme name; Index of strain; Index of company; Index of starting material; Index of product |
| Record Nr. | UNINA-9910830852603321 |
| Weinheim, : Wiley-VCH | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Industrial biotransformations / / edited by Andreas Liese, Karsten Seelbach, Christian Wandrey
| Industrial biotransformations / / edited by Andreas Liese, Karsten Seelbach, Christian Wandrey |
| Edizione | [2nd completely rev and extened ed.] |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH |
| Descrizione fisica | 1 online resource (572 p.) |
| Disciplina | 660.63 |
| Altri autori (Persone) |
LieseA (Andreas)
SeelbachK (Karsten) WandreyChristian <1943-> |
| Soggetto topico |
Biotransformation (Metabolism)
Biochemical engineering |
| ISBN |
9786610723362
9781280723360 128072336X 9783527608188 3527608184 9783527607907 3527607900 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Industrial Biotransformations; Contents; Preface to the first edition; Preface to the second edition; List of Contributors; 1 History of Industrial Biotransformations - Dreams and Realities; 1.1 From the "Flower of Vinegar" to Recombinant E. Coli - The History of Microbial Biotransformations; 1.2 From Gastric Juice to SweetzymeT - The History of Enzymatic Biotransformations; 1.3 From Wine Bottle to a State-of-the-Art Facility - The History of Biochemical Engineering; 1.4 Advantages of Biotransformations Over Classical Chemistry Enzymes are proteins, things of beauty and a joy forever [40]
2 The Enzyme Classification2.1 Enzyme Nomenclature; 2.2 Enzyme Classes; 2.2.1 EC 1 Oxidoreductases; 2.2.2 EC 2 Transferases; 2.2.3 EC 3 Hydrolases; 2.2.4 EC 4 Lyases; 2.2.5 EC 5 Isomerases; 2.2.6 EC 6 Ligases; 3 Retrosynthetic Biocatalysis; 3.1 Alkanes; 3.2 Alkenes; 3.3 Amines; 3.4 Alcohols; 3.5 Aldehydes; 3.6 Ketones; 3.7 Epoxides; 3.8 Diols; 3.9 Carboxylic Acids; 3.10 Esters; 3.11 Amides; 3.12 Imines; 3.13 Amino Acids; 3.14 Hydroxy Acids; 3.15 α-Hydroxy Ketones; 3.16 β-Hydroxy Aldehydes, Ketones or Carboxylic Acids; 3.17 Cyanohydrins, Hemithioacetals and Hemiaminals 3.18 Sulfoxides and Sulfones3.19 Halides; 3.20 Aromatics (Ring Functionalization); 3.21 Cyclic Compounds; 3.22 Carbohydrates; 3.23 Peroxides; 3.24 Isomers; 3.25 Examples of Retrosynthetic Biotransformations; 3.25.1 Example 1; 3.25.2 Example 2; 4 Optimization of Industrial Enzymes by Molecular Engineering; 4.1 Introduction; 4.2 Learning from Nature; 4.3 Enzyme Production Using Bacterial Expression Hosts; 4.4 Improvements to Enzymes by Molecular Engineering Techniques; 4.4.1 Rational Enzyme Design; 4.4.2 Directed Evolution; 4.4.3 Random Mutagenesis Methods 4.5 Identification of Improved Enzyme Variants4.6 Conclusions and Future Prospects; 5 Basics of Bioreaction Engineering; 5.1 Definitions; 5.1.1 Process Definitions; 5.1.2 Definitions of Unit Operations; 5.2 Biocatalyst Kinetics; 5.2.1 Types of Biocatalysts; 5.2.2 Enzyme Structure; 5.2.3 Kinetics; 5.3 Basic Reactor Types and their Modes of Operation; 5.3.1 Mass and Energy Balances; 5.4 Biocatalyst Recycling and Recovery; 5.4.1 Entrapment; 5.4.2 Cross-linking; 5.4.3 Covalent Binding; 5.4.4 Membrane Filtration; 5.5 Reaction Parameters; 5.6 Scale-up of Bioreactors 5.7 Recent Developments and Trends6 Processes; Oxireductases EC 1; Transferases EC 2; Hydrolases EC 3; Lyases EC 4; Isomerases EC 5; 7 Quantitative Analysis of Industrial Biotransformations; Index; Index of enzyme name; Index of strain; Index of company; Index of starting material; Index of product |
| Record Nr. | UNINA-9911019898003321 |
| Weinheim, : Wiley-VCH | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Introduction to Enzyme Technology / / edited by Karl-Erich Jaeger, Andreas Liese, Christoph Syldatk
| Introduction to Enzyme Technology / / edited by Karl-Erich Jaeger, Andreas Liese, Christoph Syldatk |
| Autore | Jaeger Karl-Erich |
| Edizione | [1st ed. 2024.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2024 |
| Descrizione fisica | 1 online resource (467 pages) |
| Disciplina | 660.634 |
| Altri autori (Persone) |
LieseA (Andreas)
SyldatkChristoph |
| Collana | Learning Materials in Biosciences |
| Soggetto topico |
Enzymology
Biotechnology Biology - Technique Environmental engineering Bioremediation Biological Techniques Environmental Engineering/Biotechnology |
| ISBN | 3-031-42999-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1. Introduction to enzyme technology -- Chapter 2. Enzyme structure and function -- Chapter 3. Enzyme modelling: from the sequence to the substrate complex -- Chapter 4. Enzyme kinetics -- Chapter 5. Enzyme reactors and process control -- Chapter 6. Enzyme identification and screening: activity-based methods -- Chapter 7. Bioinformatic methods for enzyme identification -- Chapter 8. Optimization of enzymes -- Chapter 9. Enzyme production -- Chapter 10. Enzyme purification -- Chapter 11. Enzyme immobilization -- Chapter 12. Enzymatic reactions in unusual reaction media -- Chapter 13. Principles of applied biocatalysis -- Chapter 14. Enzymes in the chemical and pharmaceutical industry -- Chapter 15. Enzymes for the degradation of biomass -- Chapter 16. Enzymes in food production -- Chapter 17. Enzymes in detergents and cleaning agents -- Chapter 18. Enzymes and biosensor technology -- Chapter 19. Therapeutic enzymes -- Chapter 20. Enzymes in molecular biotechnology. |
| Record Nr. | UNINA-9910845490603321 |
|
Jaeger Karl-Erich
|
||
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||