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The comprehensive sourcebook of bacterial protein toxins / / Joseph Alouf, Institut Pasteur, Paris, France, Daniel Ladant, Institut Pasteur, Unité de Biochimie des Interactions Moléculaires, Paris, France, Michel R. Popoff, Institut Pasteur, Unité des Bactéries anaérobies et Toxines, Paris, France ; contributors, Klaus Aktories [and one hundred ten others]
| The comprehensive sourcebook of bacterial protein toxins / / Joseph Alouf, Institut Pasteur, Paris, France, Daniel Ladant, Institut Pasteur, Unité de Biochimie des Interactions Moléculaires, Paris, France, Michel R. Popoff, Institut Pasteur, Unité des Bactéries anaérobies et Toxines, Paris, France ; contributors, Klaus Aktories [and one hundred ten others] |
| Autore | Alouf J. E (Joseph E.) |
| Edizione | [4th ed.] |
| Pubbl/distr/stampa | Amsterdam, Netherlands : , : Elsevier, , 2015 |
| Descrizione fisica | 1 online resource (1201 p.) |
| Disciplina | 528.2039474 |
| Soggetto topico | Bacterial toxins |
| ISBN |
0-12-800589-0
0-12-800188-7 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; The Comprehensive Sourcebook of Bacterial Protein Toxins; Copyright Page; Contents; List of Contributors; Introduction to the Fourth Edition; In memory of J. E. Alouf (1929-2014); I. Basic Genomic and Physiological Aspects of Bacterial Protein Toxins; 1 Evolutionary aspects of toxin-producing bacteria; Introduction; Molecular ecology of toxin-producing bacteria; Pathogenicity islands, horizontal gene transfer, and the prevalence of toxins; Toxins encoded by plasmids, bacteriophages, and other pathogenicity islands; PAI-encoded toxins delivered by specialized secretion systems
Molecular evolution of toxins through genetic exchangeGenetic exchange and toxin evolution; Toxin evolution and transmission in the host; Toxin evolution and transmission in the soil environment; Toxin evolution and transmission in aquatic environments; Toxin evolution and transmission in the phyllosphere; Toxin evolution in the guts of insects and other vectors; Toxin evolution in biofilms and regulation by quorum sensing; Vaccines and toxin evolution; Modular recombination of bacterial toxins; Conclusion; References 2 Mobile genetic elements and pathogenicity islands encoding bacterial toxinsIntroduction: The genome structure of prokaryotes; Protein toxins encoded by mobile genetic elements; Protein toxins encoded by plasmids; Gram-negative bacteria; Gram-positive bacteria; Protein toxins encoded by bacteriophages; Gram-negative bacteria; Gram-positive bacteria; Protein toxin genes and other mobile genetic elements; Toxins encoded by PAIs; PAIs; PAI-encoded toxins; Enterobacteria; Other Gram-negative bacteria; The bacterial T6SS; Gram-positive bacteria; Instability of PAIs; Conclusion Evolution of new pathogenic variants caused by PAIs and mobile genetic elementsHGT and the evolution of toxin families; Acknowledgments; References; 3 News and views on protein secretion systems; Introduction; Most historical secretion types; Type I secretion system; Type II secretion system; Type III secretion system; Type IV secretion system: a protein and DNA transport machine; Type V secretion system: free or surface-bound?; Type VI secretion system: weapon for bacterial warfare; How far can we go with secretion types?; Type VII secretion system Extracellular appendages and secretion typesThe type IX secretion system; What about other secretion concepts?; Bacteriocins, colicins, pyocins, contact-dependent inhibition; Cell surface lipoproteins; OM Vesicles; What about Gram-positive bacteria, then?; Closing remarks; References; II. Intracellularly Alive Bacterial Protein Toxins; 4 Diphtheria toxin; Introduction; Diphtheria toxin: from pathology to crystal structure; Symptoms, treatment, prophylaxis, and epidemiology of diphtheria; History of DT research; Regulation of DT production; The structure of DT; The mechanism of action of DT The main steps of cell intoxication |
| Record Nr. | UNINA-9910583473403321 |
Alouf J. E (Joseph E.)
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| Amsterdam, Netherlands : , : Elsevier, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Toxins : Mr Hyde or Dr Jekyll? / / Daniel Ladant and [three others], editors
| Toxins : Mr Hyde or Dr Jekyll? / / Daniel Ladant and [three others], editors |
| Pubbl/distr/stampa | Basel, Switzerland : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2023 |
| Descrizione fisica | 1 online resource (226 pages) |
| Disciplina | 363.7 |
| Soggetto topico | Toxins |
| ISBN | 3-0365-6905-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Toxins |
| Record Nr. | UNINA-9910719775603321 |
| Basel, Switzerland : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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