Arterial Chemoreceptors in Physiology and Pathophysiology / / edited by Chris Peers, Prem Kumar, Christopher Wyatt, Estelle Gauda, Colin A. Nurse, Nanduri Prabhakar |
Edizione | [1st ed. 2015.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 |
Descrizione fisica | 1 online resource (390 p.) |
Disciplina | 599.0188 |
Collana | Advances in Experimental Medicine and Biology |
Soggetto topico |
Human physiology
Pharmacology Laboratory medicine Gene expression Molecular biology Neurosciences Human Physiology Pharmacology/Toxicology Laboratory Medicine Gene Expression Molecular Medicine |
ISBN | 3-319-18440-7 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Preface -- C Peers & P Kumar -- 2 Epigenetic regulation of Carotid Body Oxygen Sensing: Clinical Implications, J. Nanduri, N. R. Prabhakar -- 3 Experimental observations on the biological significance of hydrogen sulfide in carotid body chemoreception, T.Gallego-Martin, T. Agapito, M. Ramirez, E. Olea, S. Yubero, A. Rocher, A. Gomez-Nino, A. Obeso, C. Gonzalez -- 4 The CamKKβ inhibitor STO609 causes artefacts in calcium imaging and selectively inhibits BKCa in mouse carotid body type I cells -- J. G. Jurcsisn, R. L. Pye, J. Ali, B. L. Barr and C. N. Wyatt -- 5 Tissue dynamics of the carotid body under chronic hypoxia: a computational study, A. Porzionato, D. Guidolin, V. Macchi, G. Sarasin, A. Mazzatenta, C. Di Giulio, J. Lopez-Barneo, R. De Caro -- 6 Paracrine Signaling in Glial-like Type II cells of the Rat Carotid Body, S. Murali, M. Zhang, C. A. Nurse -- 7 Selective μ and κ opioid agonists inhibit voltage-gated Ca2+ entry in isolated rat carotid body type I cells, E. M. Ricker, R. L. Pye, B. L. Barr, C. N. Wyatt -- 8 Measurement of ROS levels and membrane potential dynamics in the intact carotid body ex vivo, A. Bernardini, U. Brockmeier, E. Metzen, U. Berchner-Pfannschmidt, E. Harde, A. Acker-Palmer, D. Papkovsky, H. Acker, J. Fandrey -- 9 Acutely administered leptin increases [Ca2+]i and changes membrane conductance via modulation of BKCa channels in rat carotid body type I cells, R.L. Pye, E.J. Dunn, E.M. Ricker, B.L. Barr, C.N. Wyatt -- 10 Functional properties of mitochondria in the type-1 cell and their role in oxygen sensing, K.J. Buckler & P.J. Turner -- 11 Potentiation of hypoxic pulmonary vasoconstriction by hydrogen sulfide precursors 3-mercaptopyruvate and D-cysteine is blocked by the cystathione g lyase inhibitor propargylglycine, J. Prieto-Lloret & P. I. Aaronson -- 12 Modulation of the LKB1-AMPK signalling pathway underpins hypoxic pulmonary vasoconstriction and pulmonary hypertension, A.M. Evans, S.A. Lewis, O.A. Ogunbayo, J. Moral-Sanz -- 13 Organismal Responses to Hypoxemic Challenges, R.S. Fitzgerald, G.A. Dehghani, S. Kiihl -- 14 Effect of lipopolysacchride (LPS) exposure on structure and function of the carotid body in newborn rats, Z.R. Master, K. Kesavan, A. Mason, M. Shirahata, E.B. Gauda -- 15 Hypoxic Ventilatory Reactivity in Experimental Diabetes, M. Pokorski, M. Pozdzik, J. Antosiewicz, A. Dymecka, A. Mazzatenta, C. Di Giulio -- 16 Adenosine receptor blockade by caffeine inhibits carotid sinus nerve chemosensory activity in chronic intermittent hypoxic animals, J.F. Sacramento, C. Gonzalez, M.C. Gonzalez-Martin and S.V. Conde -- 17 Neurotrophic properties, chemosensory responses and neurogenic niche of the human carotid body, P Ortega-Sáenz, J Villadiego, R Pardal, JJ Toledo-Aral and J López-Barneo -- 18 Is the carotid body a metabolic monitor?, M. Shirahata, W-Y Tang, M.-K. Shin, V. Polotsky -- 19 Lipopolysaccharide-induced ionized hypocalcemia and acute kidney injury in carotid chemo/baro-denervated rats, R. Fernandez, P. Cortes, R. del Rio, C. Acuna-Castillo, E.P. Reyes -- 20 Role of the Carotid Body Chemoreflex in the Pathophysiology of Heart Failure: A Perspective from Animal Studies, H.D. Schultz, N. J. Marcus & R. Del Rio -- 21 A short-term fasting in neonates induces breathing instability and epigenetic modification in the carotid body, W.-Y. Tang, E. Kostuk, M. Shirahata -- 22 Carotid Body Chemoreflex Mediates Intermittent Hypoxia-Induced Oxidative Stress in the Adrenal Medulla, G.K. Kumar, Y-J. Peng, J. Nanduri, N.R. Prabhakar -- 23 The association between antihypertensive medication and blood pressure control in patients with obstructive sleep apnea, L.N. Diogo, P. Pinto, C. Bárbara, A.L. Papoila, E.C. Monteiro -- 24 An overview on the respiratory stimulant effects of caffeine and progesterone on response to hypoxia and apnea frequency in developing rats, A. Bairam, N.P. Uppari, S. Mubayed, V. Joseph -- 25 Hyperbaric oxygen therapy improves glucose homeostasis in type 2 diabetes patients: a likely involvement of the carotid bodies, P. Vera-Cruz, F. Guerreiro, M.J. Ribeiro, M.P. Guarino, S.V. Conde -- 26 Possible role of TRP channels in rat glomus cells, I. Kim, L. Fite, D. F. Donnelly, J. H. Kim, J. L. Carroll -- 27 Nitric oxide deficit is part of the maladaptive paracrine-autocrine response of the carotid body to intermittent hypoxia in sleep apnea, M.L. Fung -- 28 Respiratory control in the mdx mouse model of Duchenne muscular dystrophy , D. Burns, D. Edge, D. O’Malley, K.D. O’Halloran -- 29 Mild chronic intermittent hypoxia in Wistar rats evokes significant cardiovascular pathophysiology but no overt changes in carotid body-mediated respiratory responses, C. J. Ray, B. Dow, P. Kumar, A.M. Coney -- 30 Crucial role of the carotid body chemoreceptors on the development of high arterial blood pressure during chronic intermittent hypoxia, R. Iturriaga, D.C. Andrade, R. Del Rio -- 31 Relative contribution of nuclear and membrane progesterone receptors in respiratory control, R. Boukari, F. Marcouiller, V. Joseph -- 32 Inhibition of protein kinases AKT and ERK1/2 reduce the carotid body chemoreceptor response to hypoxia in adult rats, J. P. Iturri, V. Joseph, G. Rodrigo, A. Bairam, J. Soliz -- 33 Ecto-5’-nucleotidase, adenosine and transmembrane adenylyl cyclase signalling regulate basal carotid body chemoafferent outflow and establish the sensitivity to hypercapnia, A.P.S. Holmes, A.R. Nunes, M.J. Cann, P.Kumar -- 34 T-type Ca2+ channel regulation by CO: a mechanism for control of cell proliferation, H. Duckles, M.M. Al-Owais, J. Elies, E. Johnson, H.E. Boycott, M.L. Dallas, K.E. Porter, J.P. Boyle, J. L. Scragg, C. Peers -- 35 Glutamatergic Receptor Activation in the Commisural Nucleus Tractus Solitarii (cNTS) Mediates Brain Glucose Retention (BGR) Response to Anoxic Carotid Chemoreceptor (CChr) Stimulation in Rats, R. Cuellar, S. Montero, S. Luquin, J. Garcia-Estrada, O. Dobrovinskaya, V. Melnikov, M. Lemus, E. Roces de Alvarez-Buyll -- 36 Enhanced Serotonin (5HT) secretion in pulmonary neuroepithelial bodies from PHD-1 null mice, S. Livermore, J. Pan, H. Yeger, P. Ratcliffe, T. Bishop, E. Cutz -- 37 Selective expression of galanin in type I cells of the human carotid body, C. Di Giulio, G.D. Marconi, S. Zara, A. Di Tano, A. Porzionato, M. Pokorski, A. Cataldi, V. Macchi , A.Mazzatenta -- 38 Role of BK channels in murine carotid body neural responses in vivo, L.E. Pichard, C.M. Crainiceanu, P. Pashai, E.W. Kostuk, A. Fujioka, M. Shirahata -- 39 Chronic intermittent hypoxia blunts the expression of ventilatory long term facilitation in sleeping rats, D. Edge, KD. O’Halloran -- 40 Heme oxygenase-1 influences apoptosis via CO-mediated inhibition of K+ channels, M.M. Al-Owais, M.L. Dallas, J.P. Boyle, J. L. Scragg , C. Peers -- 41 Inhibition of T-type Ca2+ channels by hydrogen sulphide, J. Elies, JL Scragg, M. Dallas, D. Huang, S. Huang, JP Boyle, N. Gamper, C. Peers -- 42 GAL-021 and GAL-160 are efficacious in rat models of obstructive and central sleep apnea and inhibit BKCa in isolated rat carotid body glomus cells, M. Dallas, C. Peers, F.J. Golder, S. Baby, R. Grube, D.E. MacIntyre -- 43 The human carotid body gene expression and function in signaling of hypoxia and inflammation, J. Kåhlin, S. Mkrtchian, A. Ebberyd, L. I. Eriksson, M. J. Fagerlund -- 44 The Carotid Body Does Not Mediate The Acute Ventilatory Effects Of Leptin, E. Olea, M.J. Ribeiro, T.Gallego-Martin, S. Yubero, R. Rigual, JF. Masa, A. Obeso, S. V. Conde, C. Gonzalez -- 45 Concluding Remarks, E. Gauda -- Index. |
Record Nr. | UNINA-9910298459303321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Learning and performance matter [[electronic resource] /] / editors, Prem Kumar, Phil Ramsey |
Pubbl/distr/stampa | Hackensack, NJ, : World Scientific, c2008 |
Descrizione fisica | 1 online resource (264 p.) |
Disciplina | 658.3/124 |
Altri autori (Persone) |
KumarPrem
RamseyPhil |
Soggetto topico |
Organizational learning
Employees - Training of Performance |
Soggetto genere / forma | Electronic books. |
ISBN | 981-277-193-X |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
FOREWORD Dave Ulrich; CONTENTS; INTRODUCTION; 1. Learning and Performance: Rethinking the Dance Phil Ramsey; INTRODUCTION; DILEMMAS - THE FOUNDATION OF THE DANCE; DANCE STEPS OF CULTURES; DANCING TOWARD PERFORMANCE; ASSUMPTIONS; COMMITTING TO A BETTER DANCE; LEARNING'S PLACE IN ORGANISATIONS; 2. A Short History of Learning John Seely Brown and Estee Solomon Gray; IT TAKES 20 YEARS...; A DECADE DISTILLED; CREATING LEARNING CULTURES: WHAT'S NEXT?; CONCLUSION: A TWENTY-FIRST CENTURY INTUITION; 3. When Learning and Performance are at Odds: Confronting the Tension Sara J. Singer and Amy C. Edmondson
INTRODUCTIONLEARNING AND PERFORMANCE IN TEAMS AND ORGANIZATIONS; LEARNING LEADS TO PERFORMANCE IMPROVEMENT; PERFORMANCE CAN APPEAR TO SUFFER FOLLOWING A COLLECTIVE LEARNING INITIATIVE; The visibility problem; The worse-before-better problem; LEARNING FROM FAILURE IS DIFFICULT; Psychological and organizational barriers; Learning from small and large failures; THE LEARNING MINDSET ACROSS DIFFERENT LEVELS OF ANALYSIS; Advocacy and inquiry orientations; Confirmatory and exploratory responses; Learning-oriented and coping-oriented approaches; Organizational exploitation and exploration Organizing to learn and organizing to executeLEARNING COMES AT A COST TO CURRENT PERFORMANCE; LEADING ORGANIZATIONAL LEARNING; Diagnose the situation and respond accordingly; Embrace failure; Maintain flexibility and shift as needed; IMPLICATIONS FOR PERFORMANCE MEASUREMENT; CONCLUSIONS; REFERENCES; 4. The Work of Knowledge Management Made Real Margaret Wheatley and Myron Rogers; KNOWLEDGE MANAGEMENT IS A SURVIVAL SKILL; BELIEFS THAT PREVENT KNOWLEDGE MANAGEMENT; SOME PRINCIPLES THAT FACILITATE KNOWLEDGE MANAGEMENT; THE ORGANISATIONAL CHALLENGE 5. What Can Leaders Do? Marilyn J. Darling and David C. FlaniganTHE STRUCTURE OF LEARNING IN A DYNAMIC ENVIRONMENT; EMERGENT LEARNING; AFTER ACTION REVIEWS; EL Maps; WHAT CAN LEADERS DO?; 1. Build alignment around a vision and hold everyone - including yourself - accountable for getting there.; 2. Be a role model for learning: be humble and curious, and take action on learning.; 3. Insist on learning through action: treat plans as hypotheses to be tested, and link lessons from the past to plans for the future.; WHAT CAN HUMAN RESOURCES AND ORGANIZATIONAL LEARNING TEAMS DO? 1. Act as a team coach, not as an expert.2. Collaborate with leaders to identify and build training around core skills and common conditions.; 3. Coach leaders on how to create a learning climate.; WHAT'S POSSIBLE?; REFERENCES; 6. Doggie Treats and the Core Group Art Kleiner; THE NUMBERS; A SENSE OF VERNACULAR; THE PROBLEM OF BIGNESS; THE CHALLENGE; 7. Essence of Strategy: Controversial Choices Aneel Karnani; CONTROVERSIAL CHOICES; A VISION IS NOT A STRATEGY; CAUSES OF CONTROVERSY; THE PLANNING PROCESS; CONFRONTING DIFFERENCES; GENERATE CONFLICT; CONFLICT MANAGEMENT; UNDERSTANDING TRADE-OFFS CONFLICT RESOLUTION |
Record Nr. | UNINA-9910455098103321 |
Hackensack, NJ, : World Scientific, c2008 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Learning and performance matter [[electronic resource] /] / editors, Prem Kumar, Phil Ramsey |
Pubbl/distr/stampa | Hackensack, NJ, : World Scientific, c2008 |
Descrizione fisica | 1 online resource (264 p.) |
Disciplina | 658.3/124 |
Altri autori (Persone) |
KumarPrem
RamseyPhil |
Soggetto topico |
Organizational learning
Employees - Training of Performance |
ISBN | 981-277-193-X |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
FOREWORD Dave Ulrich; CONTENTS; INTRODUCTION; 1. Learning and Performance: Rethinking the Dance Phil Ramsey; INTRODUCTION; DILEMMAS - THE FOUNDATION OF THE DANCE; DANCE STEPS OF CULTURES; DANCING TOWARD PERFORMANCE; ASSUMPTIONS; COMMITTING TO A BETTER DANCE; LEARNING'S PLACE IN ORGANISATIONS; 2. A Short History of Learning John Seely Brown and Estee Solomon Gray; IT TAKES 20 YEARS...; A DECADE DISTILLED; CREATING LEARNING CULTURES: WHAT'S NEXT?; CONCLUSION: A TWENTY-FIRST CENTURY INTUITION; 3. When Learning and Performance are at Odds: Confronting the Tension Sara J. Singer and Amy C. Edmondson
INTRODUCTIONLEARNING AND PERFORMANCE IN TEAMS AND ORGANIZATIONS; LEARNING LEADS TO PERFORMANCE IMPROVEMENT; PERFORMANCE CAN APPEAR TO SUFFER FOLLOWING A COLLECTIVE LEARNING INITIATIVE; The visibility problem; The worse-before-better problem; LEARNING FROM FAILURE IS DIFFICULT; Psychological and organizational barriers; Learning from small and large failures; THE LEARNING MINDSET ACROSS DIFFERENT LEVELS OF ANALYSIS; Advocacy and inquiry orientations; Confirmatory and exploratory responses; Learning-oriented and coping-oriented approaches; Organizational exploitation and exploration Organizing to learn and organizing to executeLEARNING COMES AT A COST TO CURRENT PERFORMANCE; LEADING ORGANIZATIONAL LEARNING; Diagnose the situation and respond accordingly; Embrace failure; Maintain flexibility and shift as needed; IMPLICATIONS FOR PERFORMANCE MEASUREMENT; CONCLUSIONS; REFERENCES; 4. The Work of Knowledge Management Made Real Margaret Wheatley and Myron Rogers; KNOWLEDGE MANAGEMENT IS A SURVIVAL SKILL; BELIEFS THAT PREVENT KNOWLEDGE MANAGEMENT; SOME PRINCIPLES THAT FACILITATE KNOWLEDGE MANAGEMENT; THE ORGANISATIONAL CHALLENGE 5. What Can Leaders Do? Marilyn J. Darling and David C. FlaniganTHE STRUCTURE OF LEARNING IN A DYNAMIC ENVIRONMENT; EMERGENT LEARNING; AFTER ACTION REVIEWS; EL Maps; WHAT CAN LEADERS DO?; 1. Build alignment around a vision and hold everyone - including yourself - accountable for getting there.; 2. Be a role model for learning: be humble and curious, and take action on learning.; 3. Insist on learning through action: treat plans as hypotheses to be tested, and link lessons from the past to plans for the future.; WHAT CAN HUMAN RESOURCES AND ORGANIZATIONAL LEARNING TEAMS DO? 1. Act as a team coach, not as an expert.2. Collaborate with leaders to identify and build training around core skills and common conditions.; 3. Coach leaders on how to create a learning climate.; WHAT'S POSSIBLE?; REFERENCES; 6. Doggie Treats and the Core Group Art Kleiner; THE NUMBERS; A SENSE OF VERNACULAR; THE PROBLEM OF BIGNESS; THE CHALLENGE; 7. Essence of Strategy: Controversial Choices Aneel Karnani; CONTROVERSIAL CHOICES; A VISION IS NOT A STRATEGY; CAUSES OF CONTROVERSY; THE PLANNING PROCESS; CONFRONTING DIFFERENCES; GENERATE CONFLICT; CONFLICT MANAGEMENT; UNDERSTANDING TRADE-OFFS CONFLICT RESOLUTION |
Record Nr. | UNINA-9910778077903321 |
Hackensack, NJ, : World Scientific, c2008 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Learning and performance matter / / editors, Prem Kumar, Phil Ramsey |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Hackensack, NJ, : World Scientific, c2008 |
Descrizione fisica | 1 online resource (264 p.) |
Disciplina | 658.3/124 |
Altri autori (Persone) |
KumarPrem
RamseyPhil |
Soggetto topico |
Organizational learning
Employees - Training of Performance |
ISBN | 981-277-193-X |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
FOREWORD Dave Ulrich; CONTENTS; INTRODUCTION; 1. Learning and Performance: Rethinking the Dance Phil Ramsey; INTRODUCTION; DILEMMAS - THE FOUNDATION OF THE DANCE; DANCE STEPS OF CULTURES; DANCING TOWARD PERFORMANCE; ASSUMPTIONS; COMMITTING TO A BETTER DANCE; LEARNING'S PLACE IN ORGANISATIONS; 2. A Short History of Learning John Seely Brown and Estee Solomon Gray; IT TAKES 20 YEARS...; A DECADE DISTILLED; CREATING LEARNING CULTURES: WHAT'S NEXT?; CONCLUSION: A TWENTY-FIRST CENTURY INTUITION; 3. When Learning and Performance are at Odds: Confronting the Tension Sara J. Singer and Amy C. Edmondson
INTRODUCTIONLEARNING AND PERFORMANCE IN TEAMS AND ORGANIZATIONS; LEARNING LEADS TO PERFORMANCE IMPROVEMENT; PERFORMANCE CAN APPEAR TO SUFFER FOLLOWING A COLLECTIVE LEARNING INITIATIVE; The visibility problem; The worse-before-better problem; LEARNING FROM FAILURE IS DIFFICULT; Psychological and organizational barriers; Learning from small and large failures; THE LEARNING MINDSET ACROSS DIFFERENT LEVELS OF ANALYSIS; Advocacy and inquiry orientations; Confirmatory and exploratory responses; Learning-oriented and coping-oriented approaches; Organizational exploitation and exploration Organizing to learn and organizing to executeLEARNING COMES AT A COST TO CURRENT PERFORMANCE; LEADING ORGANIZATIONAL LEARNING; Diagnose the situation and respond accordingly; Embrace failure; Maintain flexibility and shift as needed; IMPLICATIONS FOR PERFORMANCE MEASUREMENT; CONCLUSIONS; REFERENCES; 4. The Work of Knowledge Management Made Real Margaret Wheatley and Myron Rogers; KNOWLEDGE MANAGEMENT IS A SURVIVAL SKILL; BELIEFS THAT PREVENT KNOWLEDGE MANAGEMENT; SOME PRINCIPLES THAT FACILITATE KNOWLEDGE MANAGEMENT; THE ORGANISATIONAL CHALLENGE 5. What Can Leaders Do? Marilyn J. Darling and David C. FlaniganTHE STRUCTURE OF LEARNING IN A DYNAMIC ENVIRONMENT; EMERGENT LEARNING; AFTER ACTION REVIEWS; EL Maps; WHAT CAN LEADERS DO?; 1. Build alignment around a vision and hold everyone - including yourself - accountable for getting there.; 2. Be a role model for learning: be humble and curious, and take action on learning.; 3. Insist on learning through action: treat plans as hypotheses to be tested, and link lessons from the past to plans for the future.; WHAT CAN HUMAN RESOURCES AND ORGANIZATIONAL LEARNING TEAMS DO? 1. Act as a team coach, not as an expert.2. Collaborate with leaders to identify and build training around core skills and common conditions.; 3. Coach leaders on how to create a learning climate.; WHAT'S POSSIBLE?; REFERENCES; 6. Doggie Treats and the Core Group Art Kleiner; THE NUMBERS; A SENSE OF VERNACULAR; THE PROBLEM OF BIGNESS; THE CHALLENGE; 7. Essence of Strategy: Controversial Choices Aneel Karnani; CONTROVERSIAL CHOICES; A VISION IS NOT A STRATEGY; CAUSES OF CONTROVERSY; THE PLANNING PROCESS; CONFRONTING DIFFERENCES; GENERATE CONFLICT; CONFLICT MANAGEMENT; UNDERSTANDING TRADE-OFFS CONFLICT RESOLUTION |
Record Nr. | UNINA-9910822681103321 |
Hackensack, NJ, : World Scientific, c2008 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|