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AIDS and tuberculosis [[electronic resource] ] : a deadly liaison / / ed. by Stefan H. E. Kaufmann and Bruce D. Walker
AIDS and tuberculosis [[electronic resource] ] : a deadly liaison / / ed. by Stefan H. E. Kaufmann and Bruce D. Walker
Pubbl/distr/stampa Weinheim, : Wiley-VCH, 2009
Descrizione fisica 1 online resource (322 p.)
Disciplina 616.9792
616.9792 20
Altri autori (Persone) KaufmannS. H. E (Stefan H. E.)
Collana Infection biology handbook series
Soggetto topico AIDS (Disease) - Complications
Tuberculosis
ISBN 1-282-30250-7
9786612302503
3-527-62790-1
3-527-62791-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto AIDS and Tuberculosis: A Deadly Liaison; Contents; Preface; List of Contributors; Part One: Immunology and Vaccination Strategies for AIDS and TB; 1 HIV Immunology and Prospects for Vaccines; 1.1 Introduction; 1.2 Challenges for HIV Vaccine Design; 1.3 What Immune Responses will be Required for an Effective AIDS Vaccine?; 1.3.1 Cytotoxic T Lymphocytes; 1.3.2 Neutralizing Antibodies; 1.3.3 CD4+ T Helper Cells; 1.3.4 Natural Killer Cells; 1.4 Models of Successful Vaccination?; 1.5 Human Trials of AIDS Vaccines; 1.5.1 Antibody-Based Vaccination; 1.5.1.1 VaxGen Trial of AIDSVax
1.5.2 T Cell-Based Vaccination1.5.2.1 The STEP Study; 1.6 Recent Advances in Animal Models: Reasons for Optimism; 1.6.1 Success against Heterologous Challenge; 1.6.2 Heterologous rAd26 Prime/rAd5 Boost Vaccine Regimen; 1.6.3 Induction of Effector Memory T-Cell Responses at Viral Entry Sites; 1.7 The Current Vaccine Pipeline; 1.7.1 DNA; 1.7.2 Adenovirus; 1.7.3 Peptides; 1.7.4 Bacillus Calmette-Guérin; 1.7.5 Listeria and Other Bacterial Vectors; 1.7.5.1 Listeria monocytogenes; 1.7.5.2 Salmonella enterica; 1.7.5.3 Shigella; 1.7.6 Canarypox; 1.7.7 Adeno-Associated Virus
1.8 Conclusions and Future DirectionsReferences; 2 Immune Response to Tuberculosis as a Basis for Rational Vaccination Strategies; 2.1 Introduction; 2.2 Clinical Aspects of TB; 2.3 Immune Response to TB: Innate Immunity; 2.4 Adaptive Immunity; 2.4.1 T-Cell Subsets; 2.4.2 T-Cell Activation; 2.5 Cytokines as Mediators of Immune Function; 2.5.1 IL-12 Family of Cytokines; 2.5.2 Tumor Necrosis Factor; 2.6 Vaccines against TB; 2.6.1 From the Past to the Present; 2.6.2 The Future; 2.6.2.1 Goals of Vaccination; 2.6.2.2 Vaccination Strategies; 2.6.2.3 Targets for Vaccination; 2.7 Biomarkers
2.7.1 Immunologic2.7.2 Transcriptomics; 2.7.3 Proteomics; 2.7.4 Metabolomics; 2.8 Concluding Remarks; References; 3 BCG Vaccination in the HIV+Newborn; 3.1 Bacillus Calmette-Gu erin (BCG) and its Efficacy in Healthy Infants; 3.2 Adverse Events Caused by BCG in Healthy Infants; 3.3 Specific Immunity Induced by BCG in Healthy Infants; 3.4 Efficacy of BCG to Prevent TB in HIV-Infected Infants; 3.5 Adverse Effects Caused by BCG in HIV-Infected Infants not Receiving Antiretroviral Therapy; 3.6 BCG Immune Reconstitution Inflammatory Syndrome (BCG-IRIS)
3.7 Management of BCG Disease in HIV-Infected Infants3.8 Specific Immunity Induced by BCG in HIV-Infected Infants; 3.9 Weighing up the Evidence: Should BCG be given to HIV-Infected or HIV-Exposed Infants?; 3.10 How Can We Protect HIV-Infected Infants Against TB, if BCG is Not Given?; 3.11 BCG Vaccination of HIV-Exposed, Uninfected Infants; 3.12 Conclusions; References; Part Two: Drugs; 4 HIV/AIDS Drugs; 4.1 Introduction; 4.2 Nucleoside Analogue Reverse Transcriptase Inhibitors (NRTIs); 4.3 Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs); 4.4 HIV Protease Inhibitors
4.5 Newer Classes: Entry Inhibitors and Integrase Inhibitors
Record Nr. UNINA-9910139928003321
Weinheim, : Wiley-VCH, 2009
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
AIDS and tuberculosis [[electronic resource] ] : a deadly liaison / / ed. by Stefan H. E. Kaufmann and Bruce D. Walker
AIDS and tuberculosis [[electronic resource] ] : a deadly liaison / / ed. by Stefan H. E. Kaufmann and Bruce D. Walker
Pubbl/distr/stampa Weinheim, : Wiley-VCH, 2009
Descrizione fisica 1 online resource (322 p.)
Disciplina 616.9792
616.9792 20
Altri autori (Persone) KaufmannS. H. E (Stefan H. E.)
Collana Infection biology handbook series
Soggetto topico AIDS (Disease) - Complications
Tuberculosis
ISBN 1-282-30250-7
9786612302503
3-527-62790-1
3-527-62791-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto AIDS and Tuberculosis: A Deadly Liaison; Contents; Preface; List of Contributors; Part One: Immunology and Vaccination Strategies for AIDS and TB; 1 HIV Immunology and Prospects for Vaccines; 1.1 Introduction; 1.2 Challenges for HIV Vaccine Design; 1.3 What Immune Responses will be Required for an Effective AIDS Vaccine?; 1.3.1 Cytotoxic T Lymphocytes; 1.3.2 Neutralizing Antibodies; 1.3.3 CD4+ T Helper Cells; 1.3.4 Natural Killer Cells; 1.4 Models of Successful Vaccination?; 1.5 Human Trials of AIDS Vaccines; 1.5.1 Antibody-Based Vaccination; 1.5.1.1 VaxGen Trial of AIDSVax
1.5.2 T Cell-Based Vaccination1.5.2.1 The STEP Study; 1.6 Recent Advances in Animal Models: Reasons for Optimism; 1.6.1 Success against Heterologous Challenge; 1.6.2 Heterologous rAd26 Prime/rAd5 Boost Vaccine Regimen; 1.6.3 Induction of Effector Memory T-Cell Responses at Viral Entry Sites; 1.7 The Current Vaccine Pipeline; 1.7.1 DNA; 1.7.2 Adenovirus; 1.7.3 Peptides; 1.7.4 Bacillus Calmette-Guérin; 1.7.5 Listeria and Other Bacterial Vectors; 1.7.5.1 Listeria monocytogenes; 1.7.5.2 Salmonella enterica; 1.7.5.3 Shigella; 1.7.6 Canarypox; 1.7.7 Adeno-Associated Virus
1.8 Conclusions and Future DirectionsReferences; 2 Immune Response to Tuberculosis as a Basis for Rational Vaccination Strategies; 2.1 Introduction; 2.2 Clinical Aspects of TB; 2.3 Immune Response to TB: Innate Immunity; 2.4 Adaptive Immunity; 2.4.1 T-Cell Subsets; 2.4.2 T-Cell Activation; 2.5 Cytokines as Mediators of Immune Function; 2.5.1 IL-12 Family of Cytokines; 2.5.2 Tumor Necrosis Factor; 2.6 Vaccines against TB; 2.6.1 From the Past to the Present; 2.6.2 The Future; 2.6.2.1 Goals of Vaccination; 2.6.2.2 Vaccination Strategies; 2.6.2.3 Targets for Vaccination; 2.7 Biomarkers
2.7.1 Immunologic2.7.2 Transcriptomics; 2.7.3 Proteomics; 2.7.4 Metabolomics; 2.8 Concluding Remarks; References; 3 BCG Vaccination in the HIV+Newborn; 3.1 Bacillus Calmette-Gu erin (BCG) and its Efficacy in Healthy Infants; 3.2 Adverse Events Caused by BCG in Healthy Infants; 3.3 Specific Immunity Induced by BCG in Healthy Infants; 3.4 Efficacy of BCG to Prevent TB in HIV-Infected Infants; 3.5 Adverse Effects Caused by BCG in HIV-Infected Infants not Receiving Antiretroviral Therapy; 3.6 BCG Immune Reconstitution Inflammatory Syndrome (BCG-IRIS)
3.7 Management of BCG Disease in HIV-Infected Infants3.8 Specific Immunity Induced by BCG in HIV-Infected Infants; 3.9 Weighing up the Evidence: Should BCG be given to HIV-Infected or HIV-Exposed Infants?; 3.10 How Can We Protect HIV-Infected Infants Against TB, if BCG is Not Given?; 3.11 BCG Vaccination of HIV-Exposed, Uninfected Infants; 3.12 Conclusions; References; Part Two: Drugs; 4 HIV/AIDS Drugs; 4.1 Introduction; 4.2 Nucleoside Analogue Reverse Transcriptase Inhibitors (NRTIs); 4.3 Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs); 4.4 HIV Protease Inhibitors
4.5 Newer Classes: Entry Inhibitors and Integrase Inhibitors
Record Nr. UNINA-9910831001303321
Weinheim, : Wiley-VCH, 2009
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Concepts in vaccine development / / editor, Stefan H.E. Kaufmann
Concepts in vaccine development / / editor, Stefan H.E. Kaufmann
Edizione [Reprint 2012]
Pubbl/distr/stampa Berlin ; ; New York : , : Walter de Gruyter, , 1996
Descrizione fisica 1 online resource (605 pages) : illustrations
Disciplina 615/.372
Altri autori (Persone) KaufmannS. H. E (Stefan H. E.)
Soggetto topico Vaccines
Immunization
Soggetto genere / forma Electronic books.
ISBN 3-11-090666-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front matter -- Preface -- Bicentennial of the first vaccination by Edward Jenner / Kaufmann, Stefan H.E. -- Contents -- 1. The Need for New Vaccines -- 1.1. Vaccines as Evolutionary Tools: The Virulence-Antigen Strategy / Ewald, Paul W. -- 1.2. Economic Perspectives on Vaccine Needs / Ashley, Robert V. / Murray, Christopher J. L. -- 1.3. Future Immunization Strategies - Considerations from the Public Health View / Dittmann, Sieghart -- 1.4. The New Pertussis Vaccines / Klein, David L. / Heilman, Carole -- 2. General Principles of Immunology -- 2.1. Basic Principles of Immunity Against Intracellular Bacteria and Protozoa / Szalay, Gudrun / Kaufmann, Stefan H. E. -- 2.2. Viral Immunity and Vaccine Strategies / Woodland, David L. / Cole, Geoffrey A. / Doherty, Peter C. -- 2.3. Broadly Reactive HLA Restricted Τ Cell Epitopes and Their Implications for Vaccine Design / Sidney, John / Kubo, Ralph T. / Wentworth, Peggy A. / Alexander, Jeff / Chesnut, Robert W. / Grey, Howard M. / Sette, Alessandro -- 2.4. Quantitative Considerations in the Design of Vaccination Strategies Against Pathogens Uniquely Susceptible to Cell-Mediated Attack / Bretscher, Peter -- 2.5. The Impact of the Type 1 and Type 2 Τ Helper Cell Concept on Novel Vaccine Design with Emphasis on Protection Against Leishmania Parasites / Bogdan, Christian / Röllinghoff, Martin -- 3. General Principles of Vaccinology -- 3.1. Modern Adjuvants. Functional Aspects / Morein, Bror / Lövgren-Bengtsson, Karin / Cox, John -- 3.2. Biodegradable Microspheres as Vehicles for Antigens / Kersten, Gideon F.A. / Gander, Bruno -- 3.3. Peptide Based Vaccines / Schild, Hansjörg / Rammensee, Hans-Georg -- 3.4. Recombinant Bacteria as Vaccine Carriers of Heterologous Antigens / Hormaeche, Carlos E. / Khan, C. M. Anjam -- 3.5. Genetic Detoxification of Bacterial Toxins / Rappuoli, Rino / Pizza, Mariagrazia -- 3.6. Recombinant Virus as Vaccination Carrier of Heterologous Antigens / Perkus, Marion E. / Paoletti, Enzo -- 3.7. Naked DNA Vaccination / Shiver, John W. / Ulmer, Jeffrey B. / Donnelly, John J. / Liu, Margaret A. -- 3.8. Oral Vaccination, Mucosal Immunity and Oral Tolerance with Special Reference to Cholera Toxin / Holmgren, Jan / Czerkinsky, Cecil / Sun, Jia-Bin / Svennerholm, Ann-Mari -- 4. Specific Vaccination Strategies -- 4.1. Helicobacter pylori: Pathogenic Determinants and Strategies for Vaccine Design / Ghiara, Paolo / Covacci, Antonello / Telford, John L. / Rappuoli, Rino -- 4.2. Malaria Vaccination / Patarroyo, Manuel E. / Amador, Roberto -- 4.3. Vaccination Against Schistosomiasis: Concepts and Strategies / Riveau, Gilles J. / Capron, André -- 4.4. AIDS Vaccination / Norley, Stephen / Kurth, Reinhard -- 4.5. Vaccination Therapy Against Autoimmune Diseases / Cohen, Irun R. / Mor, Felix -- Contributors -- Index
Record Nr. UNINA-9910464158903321
Berlin ; ; New York : , : Walter de Gruyter, , 1996
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Concepts in vaccine development / / editor, Stefan H.E. Kaufmann
Concepts in vaccine development / / editor, Stefan H.E. Kaufmann
Edizione [Reprint 2012]
Pubbl/distr/stampa Berlin ; ; New York : , : Walter de Gruyter, , 1996
Descrizione fisica 1 online resource (605 pages) : illustrations
Disciplina 615/.372
Altri autori (Persone) KaufmannS. H. E (Stefan H. E.)
Soggetto topico Vaccines
Immunization
ISBN 3-11-090666-X
Classificazione XD 3300
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front matter -- Preface -- Bicentennial of the first vaccination by Edward Jenner / Kaufmann, Stefan H.E. -- Contents -- 1. The Need for New Vaccines -- 1.1. Vaccines as Evolutionary Tools: The Virulence-Antigen Strategy / Ewald, Paul W. -- 1.2. Economic Perspectives on Vaccine Needs / Ashley, Robert V. / Murray, Christopher J. L. -- 1.3. Future Immunization Strategies - Considerations from the Public Health View / Dittmann, Sieghart -- 1.4. The New Pertussis Vaccines / Klein, David L. / Heilman, Carole -- 2. General Principles of Immunology -- 2.1. Basic Principles of Immunity Against Intracellular Bacteria and Protozoa / Szalay, Gudrun / Kaufmann, Stefan H. E. -- 2.2. Viral Immunity and Vaccine Strategies / Woodland, David L. / Cole, Geoffrey A. / Doherty, Peter C. -- 2.3. Broadly Reactive HLA Restricted Τ Cell Epitopes and Their Implications for Vaccine Design / Sidney, John / Kubo, Ralph T. / Wentworth, Peggy A. / Alexander, Jeff / Chesnut, Robert W. / Grey, Howard M. / Sette, Alessandro -- 2.4. Quantitative Considerations in the Design of Vaccination Strategies Against Pathogens Uniquely Susceptible to Cell-Mediated Attack / Bretscher, Peter -- 2.5. The Impact of the Type 1 and Type 2 Τ Helper Cell Concept on Novel Vaccine Design with Emphasis on Protection Against Leishmania Parasites / Bogdan, Christian / Röllinghoff, Martin -- 3. General Principles of Vaccinology -- 3.1. Modern Adjuvants. Functional Aspects / Morein, Bror / Lövgren-Bengtsson, Karin / Cox, John -- 3.2. Biodegradable Microspheres as Vehicles for Antigens / Kersten, Gideon F.A. / Gander, Bruno -- 3.3. Peptide Based Vaccines / Schild, Hansjörg / Rammensee, Hans-Georg -- 3.4. Recombinant Bacteria as Vaccine Carriers of Heterologous Antigens / Hormaeche, Carlos E. / Khan, C. M. Anjam -- 3.5. Genetic Detoxification of Bacterial Toxins / Rappuoli, Rino / Pizza, Mariagrazia -- 3.6. Recombinant Virus as Vaccination Carrier of Heterologous Antigens / Perkus, Marion E. / Paoletti, Enzo -- 3.7. Naked DNA Vaccination / Shiver, John W. / Ulmer, Jeffrey B. / Donnelly, John J. / Liu, Margaret A. -- 3.8. Oral Vaccination, Mucosal Immunity and Oral Tolerance with Special Reference to Cholera Toxin / Holmgren, Jan / Czerkinsky, Cecil / Sun, Jia-Bin / Svennerholm, Ann-Mari -- 4. Specific Vaccination Strategies -- 4.1. Helicobacter pylori: Pathogenic Determinants and Strategies for Vaccine Design / Ghiara, Paolo / Covacci, Antonello / Telford, John L. / Rappuoli, Rino -- 4.2. Malaria Vaccination / Patarroyo, Manuel E. / Amador, Roberto -- 4.3. Vaccination Against Schistosomiasis: Concepts and Strategies / Riveau, Gilles J. / Capron, André -- 4.4. AIDS Vaccination / Norley, Stephen / Kurth, Reinhard -- 4.5. Vaccination Therapy Against Autoimmune Diseases / Cohen, Irun R. / Mor, Felix -- Contributors -- Index
Record Nr. UNINA-9910788701803321
Berlin ; ; New York : , : Walter de Gruyter, , 1996
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Concepts in vaccine development / / editor, Stefan H.E. Kaufmann
Concepts in vaccine development / / editor, Stefan H.E. Kaufmann
Edizione [Reprint 2012]
Pubbl/distr/stampa Berlin ; ; New York : , : Walter de Gruyter, , 1996
Descrizione fisica 1 online resource (605 pages) : illustrations
Disciplina 615/.372
Altri autori (Persone) KaufmannS. H. E (Stefan H. E.)
Soggetto topico Vaccines
Immunization
ISBN 3-11-090666-X
Classificazione XD 3300
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front matter -- Preface -- Bicentennial of the first vaccination by Edward Jenner / Kaufmann, Stefan H.E. -- Contents -- 1. The Need for New Vaccines -- 1.1. Vaccines as Evolutionary Tools: The Virulence-Antigen Strategy / Ewald, Paul W. -- 1.2. Economic Perspectives on Vaccine Needs / Ashley, Robert V. / Murray, Christopher J. L. -- 1.3. Future Immunization Strategies - Considerations from the Public Health View / Dittmann, Sieghart -- 1.4. The New Pertussis Vaccines / Klein, David L. / Heilman, Carole -- 2. General Principles of Immunology -- 2.1. Basic Principles of Immunity Against Intracellular Bacteria and Protozoa / Szalay, Gudrun / Kaufmann, Stefan H. E. -- 2.2. Viral Immunity and Vaccine Strategies / Woodland, David L. / Cole, Geoffrey A. / Doherty, Peter C. -- 2.3. Broadly Reactive HLA Restricted Τ Cell Epitopes and Their Implications for Vaccine Design / Sidney, John / Kubo, Ralph T. / Wentworth, Peggy A. / Alexander, Jeff / Chesnut, Robert W. / Grey, Howard M. / Sette, Alessandro -- 2.4. Quantitative Considerations in the Design of Vaccination Strategies Against Pathogens Uniquely Susceptible to Cell-Mediated Attack / Bretscher, Peter -- 2.5. The Impact of the Type 1 and Type 2 Τ Helper Cell Concept on Novel Vaccine Design with Emphasis on Protection Against Leishmania Parasites / Bogdan, Christian / Röllinghoff, Martin -- 3. General Principles of Vaccinology -- 3.1. Modern Adjuvants. Functional Aspects / Morein, Bror / Lövgren-Bengtsson, Karin / Cox, John -- 3.2. Biodegradable Microspheres as Vehicles for Antigens / Kersten, Gideon F.A. / Gander, Bruno -- 3.3. Peptide Based Vaccines / Schild, Hansjörg / Rammensee, Hans-Georg -- 3.4. Recombinant Bacteria as Vaccine Carriers of Heterologous Antigens / Hormaeche, Carlos E. / Khan, C. M. Anjam -- 3.5. Genetic Detoxification of Bacterial Toxins / Rappuoli, Rino / Pizza, Mariagrazia -- 3.6. Recombinant Virus as Vaccination Carrier of Heterologous Antigens / Perkus, Marion E. / Paoletti, Enzo -- 3.7. Naked DNA Vaccination / Shiver, John W. / Ulmer, Jeffrey B. / Donnelly, John J. / Liu, Margaret A. -- 3.8. Oral Vaccination, Mucosal Immunity and Oral Tolerance with Special Reference to Cholera Toxin / Holmgren, Jan / Czerkinsky, Cecil / Sun, Jia-Bin / Svennerholm, Ann-Mari -- 4. Specific Vaccination Strategies -- 4.1. Helicobacter pylori: Pathogenic Determinants and Strategies for Vaccine Design / Ghiara, Paolo / Covacci, Antonello / Telford, John L. / Rappuoli, Rino -- 4.2. Malaria Vaccination / Patarroyo, Manuel E. / Amador, Roberto -- 4.3. Vaccination Against Schistosomiasis: Concepts and Strategies / Riveau, Gilles J. / Capron, André -- 4.4. AIDS Vaccination / Norley, Stephen / Kurth, Reinhard -- 4.5. Vaccination Therapy Against Autoimmune Diseases / Cohen, Irun R. / Mor, Felix -- Contributors -- Index
Record Nr. UNINA-9910815140603321
Berlin ; ; New York : , : Walter de Gruyter, , 1996
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
The immune response to infection [[electronic resource] /] / edited by Stefan H.E. Kaufmann, Barry T. Rouse, David L. Sacks
The immune response to infection [[electronic resource] /] / edited by Stefan H.E. Kaufmann, Barry T. Rouse, David L. Sacks
Pubbl/distr/stampa Washington, DC, : ASM Press, c2011
Descrizione fisica 1 online resource (700 p.)
Disciplina 616.07/9
616.90479
Altri autori (Persone) KaufmannS. H. E (Stefan H. E.)
RouseBarry T
SacksDavid Lawrence
Soggetto topico Immune response
Infection
ISBN 1-68367-119-8
1-283-03446-8
9786613034465
1-55581-687-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Contributors; Preface; The Immune Response to Infection: Introduction; SECTION I: HOST DEFENSE: GENERAL; SECTION II: THE PATHOGENS; SECTION III: INNATE IMMUNITY TO MICROBIAL INFECTIONS; SECTION IV: ACQUIRED IMMUNITY TO MICROBIAL INFECTIONS; SECTION V: PATHOLOGY AND PATHOGENESIS; SECTION VI: EVASION AND SUPPRESSION OF THE ANTIMICROBIAL HOST RESPONSE; SECTION VII: GENETICS OF THE ANTIMICROBIAL HOST RESPONSE; SECTION VIII: AUTOIMMUNITY AND CANCER; SECTION IX: IMMUNE INTERVENTION; SECTION X: THE MAJOR KILLERS (CLINICS, EPIDEMIOLOGY, AND IMMUNE PARAMETERS); Index
Record Nr. UNINA-9910574098003321
Washington, DC, : ASM Press, c2011
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
The immune response to infection [[electronic resource] /] / edited by Stefan H.E. Kaufmann, Barry T. Rouse, David L. Sacks
The immune response to infection [[electronic resource] /] / edited by Stefan H.E. Kaufmann, Barry T. Rouse, David L. Sacks
Pubbl/distr/stampa Washington, DC, : ASM Press, c2011
Descrizione fisica 1 online resource (700 p.)
Disciplina 616.07/9
616.90479
Altri autori (Persone) KaufmannS. H. E (Stefan H. E.)
RouseBarry T
SacksDavid Lawrence
Soggetto topico Immune response
Infection
ISBN 1-68367-119-8
1-283-03446-8
9786613034465
1-55581-687-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Contributors; Preface; The Immune Response to Infection: Introduction; SECTION I: HOST DEFENSE: GENERAL; SECTION II: THE PATHOGENS; SECTION III: INNATE IMMUNITY TO MICROBIAL INFECTIONS; SECTION IV: ACQUIRED IMMUNITY TO MICROBIAL INFECTIONS; SECTION V: PATHOLOGY AND PATHOGENESIS; SECTION VI: EVASION AND SUPPRESSION OF THE ANTIMICROBIAL HOST RESPONSE; SECTION VII: GENETICS OF THE ANTIMICROBIAL HOST RESPONSE; SECTION VIII: AUTOIMMUNITY AND CANCER; SECTION IX: IMMUNE INTERVENTION; SECTION X: THE MAJOR KILLERS (CLINICS, EPIDEMIOLOGY, AND IMMUNE PARAMETERS); Index
Record Nr. UNINA-9910830328203321
Washington, DC, : ASM Press, c2011
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Novel vaccination strategies [[electronic resource] /] / edited by Stefan H.E. Kaufmann
Novel vaccination strategies [[electronic resource] /] / edited by Stefan H.E. Kaufmann
Pubbl/distr/stampa Weinheim, : Wiley-VCH, c2004
Descrizione fisica 1 online resource (672 p.)
Disciplina 615.372
Altri autori (Persone) KaufmannS. H. E (Stefan H. E.)
Soggetto topico Vaccines
Vaccines - Synthesis
Vacunes
Vacunació
Resposta immunitària
Soggetto genere / forma Electronic books.
Llibres electrònics
ISBN 1-280-72268-1
9786610722686
3-527-60609-2
1-280-55857-1
9786610558575
3-527-60144-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Novel Vaccination Strategies; Contents; Novel Vaccination Strategies; Preface; Acknowledgements; List of Contributors; Colour Plates; Part I; 1 Challenges for the Vaccine Developer, including Correlates of Protection; 1.1 Introduction; 1.2 Mechanisms of Protection within the Immune System; 1.3 Protection against Viruses; 1.4 HIV/AIDS as an Example of a Persisting Virus; 1.5 Protection against Extracellular Bacteria; 1.6 Protection against Intracellular Bacteria; 1.7 Protection against Parasites; 1.8 Conclusions; References; Part II Vaccination and Immune Response
2 Shaping Adaptive Immunity against Pathogens: The Contribution of Innate Immune Responses2.1 Introduction; 2.2 Activation of Innate Immunity: Sensing the Enemy; 2.2.1 Pathogen-associated Molecular Patterns; 2.2.2 Host Cellular Sensors; 2.2.2.1 Dendritic Cells; 2.2.2.2 Mast Cells; 2.2.3 Nonpeptide MHC Ligands Triggering Invariant T-cell Receptors; 2.3 Translating Innate Immune Activation into Regulatory Circuits: Molecular Pathways Shaping Adaptive Immunity; 2.3.1 TLR-initiated Signaling Cascades; 2.3.2 Molecules Involved in Recruiting Effector Cells; 2.3.2.1 Defensins; 2.3.2.2 Chemokines
2.3.3 Molecules Involved in T and B Cell Differentiation2.3.3.1 Th1-inducing Cytokines; 2.3.3.2 Th2-inducing Cytokines; 2.4 Implications for Vaccine Development; References; 3 Adjuvant-induced Th2- and Th1-dominated Immune Responses in Vaccination; 3.1 Introduction; 3.2 The Two-Signal Model of Adjuvant-induced Immune Activation; 3.3 Th1 and Th2 Induction by Vaccine Adjuvants; 3.4 Antigen Dose Effects; 3.5 The Three-signal Model of Adjuvant-induced Immune Activation; 3.6 Th2 Induction by Adjuvants; 3.7 Differential Activation of DCs; 3.8 Inappropriate Th1/Th2 Responses to Vaccines
3.9 Human Th2 vaccines3.10 Human Th1 Vaccines; 3.11 Conclusion; References; 4 Memory; 4.1 Introduction; 4.2 Characteristics of Memory Cells; 4.3 CD8+ T Cell Memory; 4.3.1 Phenotyping Memory CD8+ T Cells; 4.3.2 Enhanced Responsiveness of Memory CD8(+) T cells: Potential Mechanisms; 4.3.3 Generation of Memory CD8+ T Cells; 4.3.4 Maintaining CD8+ T Cell Memory; 4.3.5 Models of CD8+ T cell Memory Generation; 4.4 CD4+ T Cell Memory; 4.4.1 Differentiation of Effector and Memory CD4+ T Cells; 4.4.2 Phenotype of Memory CD4+ T Cells; 4.4.3 Memory Generation and Maintenance
4.4.4 Trafficking of Memory CD4+ T Cells4.5 B cell Memory; 4.5.1 Generation of B Cell Memory; 4.5.2 Maintenance of B Cell Memory; 4.6 Conclusions; Acknowledgements; References; 5 T Cell-based Vaccines; Summary; 5.1 Introduction; 5.2 Ex-vivo Detection of Antigen-specific T Cells; 5.3 In-vivo Kinetics of Antigen-specific T Cell Responses; 5.4 Effector Function and Subtypes of Effector T Cells; 5.5 T Cell Receptor Repertoire, Avidity Maturation, and Epitope Competition; 5.6 Functional Heterogeneity of T Cell Memory; 5.7 Vaccination Strategies and Their Efficacy for T Cell-based Vaccination
5.8 Concluding Remarks
Record Nr. UNINA-9910146240503321
Weinheim, : Wiley-VCH, c2004
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Novel vaccination strategies [[electronic resource] /] / edited by Stefan H.E. Kaufmann
Novel vaccination strategies [[electronic resource] /] / edited by Stefan H.E. Kaufmann
Pubbl/distr/stampa Weinheim, : Wiley-VCH, c2004
Descrizione fisica 1 online resource (672 p.)
Disciplina 615.372
Altri autori (Persone) KaufmannS. H. E (Stefan H. E.)
Soggetto topico Vaccines
Vaccines - Synthesis
Vacunes
Vacunació
Resposta immunitària
Soggetto genere / forma Llibres electrònics
ISBN 1-280-72268-1
9786610722686
3-527-60609-2
1-280-55857-1
9786610558575
3-527-60144-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Novel Vaccination Strategies; Contents; Novel Vaccination Strategies; Preface; Acknowledgements; List of Contributors; Colour Plates; Part I; 1 Challenges for the Vaccine Developer, including Correlates of Protection; 1.1 Introduction; 1.2 Mechanisms of Protection within the Immune System; 1.3 Protection against Viruses; 1.4 HIV/AIDS as an Example of a Persisting Virus; 1.5 Protection against Extracellular Bacteria; 1.6 Protection against Intracellular Bacteria; 1.7 Protection against Parasites; 1.8 Conclusions; References; Part II Vaccination and Immune Response
2 Shaping Adaptive Immunity against Pathogens: The Contribution of Innate Immune Responses2.1 Introduction; 2.2 Activation of Innate Immunity: Sensing the Enemy; 2.2.1 Pathogen-associated Molecular Patterns; 2.2.2 Host Cellular Sensors; 2.2.2.1 Dendritic Cells; 2.2.2.2 Mast Cells; 2.2.3 Nonpeptide MHC Ligands Triggering Invariant T-cell Receptors; 2.3 Translating Innate Immune Activation into Regulatory Circuits: Molecular Pathways Shaping Adaptive Immunity; 2.3.1 TLR-initiated Signaling Cascades; 2.3.2 Molecules Involved in Recruiting Effector Cells; 2.3.2.1 Defensins; 2.3.2.2 Chemokines
2.3.3 Molecules Involved in T and B Cell Differentiation2.3.3.1 Th1-inducing Cytokines; 2.3.3.2 Th2-inducing Cytokines; 2.4 Implications for Vaccine Development; References; 3 Adjuvant-induced Th2- and Th1-dominated Immune Responses in Vaccination; 3.1 Introduction; 3.2 The Two-Signal Model of Adjuvant-induced Immune Activation; 3.3 Th1 and Th2 Induction by Vaccine Adjuvants; 3.4 Antigen Dose Effects; 3.5 The Three-signal Model of Adjuvant-induced Immune Activation; 3.6 Th2 Induction by Adjuvants; 3.7 Differential Activation of DCs; 3.8 Inappropriate Th1/Th2 Responses to Vaccines
3.9 Human Th2 vaccines3.10 Human Th1 Vaccines; 3.11 Conclusion; References; 4 Memory; 4.1 Introduction; 4.2 Characteristics of Memory Cells; 4.3 CD8+ T Cell Memory; 4.3.1 Phenotyping Memory CD8+ T Cells; 4.3.2 Enhanced Responsiveness of Memory CD8(+) T cells: Potential Mechanisms; 4.3.3 Generation of Memory CD8+ T Cells; 4.3.4 Maintaining CD8+ T Cell Memory; 4.3.5 Models of CD8+ T cell Memory Generation; 4.4 CD4+ T Cell Memory; 4.4.1 Differentiation of Effector and Memory CD4+ T Cells; 4.4.2 Phenotype of Memory CD4+ T Cells; 4.4.3 Memory Generation and Maintenance
4.4.4 Trafficking of Memory CD4+ T Cells4.5 B cell Memory; 4.5.1 Generation of B Cell Memory; 4.5.2 Maintenance of B Cell Memory; 4.6 Conclusions; Acknowledgements; References; 5 T Cell-based Vaccines; Summary; 5.1 Introduction; 5.2 Ex-vivo Detection of Antigen-specific T Cells; 5.3 In-vivo Kinetics of Antigen-specific T Cell Responses; 5.4 Effector Function and Subtypes of Effector T Cells; 5.5 T Cell Receptor Repertoire, Avidity Maturation, and Epitope Competition; 5.6 Functional Heterogeneity of T Cell Memory; 5.7 Vaccination Strategies and Their Efficacy for T Cell-based Vaccination
5.8 Concluding Remarks
Record Nr. UNINA-9910830702203321
Weinheim, : Wiley-VCH, c2004
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui