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Biophysical Effects of Cold Atmospheric Plasma on Glial Tumor Cells / / by Julia Köritzer



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Autore: Köritzer Julia Visualizza persona
Titolo: Biophysical Effects of Cold Atmospheric Plasma on Glial Tumor Cells / / by Julia Köritzer Visualizza cluster
Pubblicazione: Cham : , : Springer International Publishing : , : Imprint : Springer, , 2014
Edizione: 1st ed. 2014.
Descrizione fisica: 1 online resource (85 p.)
Disciplina: 616.99481
Soggetto topico: Medical physics
Radiation
Cancer research
Plasma (Ionized gases)
Biophysics
Biological physics
Medical and Radiation Physics
Cancer Research
Plasma Physics
Biological and Medical Physics, Biophysics
Note generali: "Doctoral Thesis accepted by Ludwig Maximilian University of Munich, Germany."
Nota di bibliografia: Includes bibliographical references.
Nota di contenuto: Summary -- Introduction -- Materials and Methods -- Results -- Discussion -- Assessment and Outlook -- Supplementary Data -- References.
Sommario/riassunto: Cold atmospheric plasma is an auspicious new candidate in cancer treatment. Cold atmospheric plasma (CAP) is a partially ionized gas in which the ion temperature is close to room temperature. It contains electrons, charged particles, radicals, various excited molecules and UV photons. These various compositional elements have the potential to inhibit cancer cell activity whilst doing no harm to healthy cells. Glioblastoma (GBM) is the most common and lethal primary brain tumor in adults; treatment including surgery, radio- and chemotherapy remains palliative for most patients as a cure remains elusive. The successful combination of the standard chemotherapeutic temozolomide (TMZ) and CAP treatment features synergistic effects even in resistant glioma cells. In particular in glioma therapy, CAP could offer an innovative approach allowing specific cancer cell / tumor tissue inhibition without damaging healthy cells. Thus CAP is a promising candidate for combination therapy especially for patients suffering from GBMs showing TMZ resistance.
Titolo autorizzato: Biophysical Effects of Cold Atmospheric Plasma on Glial Tumor Cells  Visualizza cluster
ISBN: 3-319-06224-7
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910300371603321
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Serie: Springer Theses, Recognizing Outstanding Ph.D. Research, . 2190-5053