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The chemical biology of long noncoding RNAs / / Stefan Jurga, Jan Barciszewski, editors
| The chemical biology of long noncoding RNAs / / Stefan Jurga, Jan Barciszewski, editors |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (X, 544 p. 49 illus., 45 illus. in color.) |
| Disciplina | 574.87328 |
| Collana | RNA technologies |
| Soggetto topico | Nucleic acids |
| ISBN | 3-030-44743-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Long Non-Coding RNAs Diversity in Form and Function - from Microbes to Humans -- Evolving Roles of Long Noncoding RNAs -- Biogenesis and Function of the Noncoding Isoform-Type LncRNAs -- Long Non-Coding RNAs in a Single Cell Type: Function and Subcellular Localization -- Long Non-Coding RNAs as Scaffolds for Multiprotein Signalling Complexes -- Landscape of Long Non-Coding RNA Genes, Pseudogenes and Protein Genes in Segmental Duplications in the Critical Human Chromosomal Region 22q11.2 -- Long Non-Coding RNAs and Cancer Cells’ Drug Resistance: an Unexpected Connection -- Long Noncoding RNAs as Drivers of Acquired Chemoresistance in Hepatocellular Carcinoma -- Single Cell Analysis May Shed new Lights on the Role of LncRNAs in Chemo-Resistance in Gastrointestinal Cancers -- LncRNAs in the Development, Progression, and Therapy Resistance of Hormone-Dependent Cancer -- Tumorigenesis-Related Long Non-Coding RNAs and their Targeting as Therapeutic Approach in Cancer -- Long Non-Coding RNAs in Non-Small Cell Lung Cancer: State of the Art -- Long Non-Coding RNAs in Cardiovascular Diseases -- Long Non-Coding RNAs in Cardiovascular Development and Diseases.-Long Noncoding RNAs as Players in Breast Tumorigenesis -- Drosophila Models to Study Long Non-Coding RNAs Related to Neurological Disorders -- Regulatory Roles of Long Non-Coding RNAs in Skeletal Muscle Differentiation, Regeneration, and Disorders -- Long Noncoding RNAs in Substance Use Disorders -- The Multifaceted Roles of LncRNAs in Diabetic Complications: a Promising, yet Perplexing Paradigm -- Long Non-Coding RNAs in Diabetes and β-cell Regulation. |
| Record Nr. | UNINA-9910424634703321 |
| Cham, Switzerland : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The DNA, RNA, and Histone Methylomes / / edited by Stefan Jurga, Jan Barciszewski
| The DNA, RNA, and Histone Methylomes / / edited by Stefan Jurga, Jan Barciszewski |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (624 pages) |
| Disciplina |
574.1925
572.8645 |
| Collana | RNA Technologies |
| Soggetto topico |
Human genetics
Nucleic acids Genetic engineering Cell biology Human Genetics Nucleic Acid Chemistry Genetic Engineering Cell Biology |
| ISBN | 3-030-14792-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1. Establishment, Erasure and Synthetic Reprogramming of DNA Methylation in Mammalian Cells -- Chapter 2. Origin and Mechanisms of DNA Methylation Dynamics in Cancers -- Chapter 3. CpG Islands Methylation Alterations in Cancer: Functionally Intriguing Security Locks, Useful Early Tumor Biomarkers -- Chapter 4. Histone and DNA Methylome in Neurodegenerative, Neuropsychiatric and Neurodevelopmental Disorders -- Chapter 5. DNA Methylation in Neuronal Development and Disease -- Chapter 6. Functional Implications of Dynamic DNA Methylation for the Developing, Aging and Diseased Brain -- Chapter 7. The Methylome of Bipolar Disorder: Evidence from Human and Animal Studies -- Chapter 8. DNA Methylation in Multiple Sclerosis -- Chapter 9. Early Life Stress and DNA Methylation -- Chapter 10. Regulation of 5-hydroxymethylcytosine Distribution by the TET Enzymes -- Chapter 11. Epigenetic Alterations: The Relation Between Occupational Exposure and Biological Effects in Humans -- Chapter 12. DNA Methylation: Biological Implications and Modulation of its Aberrant Dysregulation -- Chapter 13. Functions and Dynamics of Methylation in Eukaryotic mRNA -- Chapter 14. The Role of mRNA m6A in Regulation of Gene Expression -- Chapter 15. G9a and G9a-like Histone Methyltransferases and Their Effect on Cell Phenotype, Embryonic Development, and Human Disease -- Chapter 16. Biomolecular Recognition of Methylated Histones -- Chapter 17. The Role of Protein Lysine Methylation in the Regulation of Protein Function - Looking Beyond the Histone Code -- Chapter 18. Secondary Structures of Histone H3 Proteins with Unmethylated and Methylated Lysine-4 and -9 Resiudes; Characterization Using Circular Dichroism Spectroscopy -- Chapter 19. Asymmetric Dimethylation on Arginine (ADMA) of Histones in Development, Differentiation and Disease -- Chapter 20. A Switch for Transcriptional Activation and Repression: Histone Arginine Methylation -- Chapter 21. Aberrant Epigenomic Regulatory Networks in Multiple Myeloma and Strategies for their Targeted Reversal -- Chapter 22. Metabolic Deregulations Affecting Chromatin Architecture: One-carbon Metabolism and Krebs Cycle Impact Histone Methylation -- Chapter 23. Histone Methylome of the Human Parasite Schistosoma Mansoni. |
| Record Nr. | UNINA-9910349446403321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Epitranscriptomics / / edited by Stefan Jurga, Jan Barciszewski
| Epitranscriptomics / / edited by Stefan Jurga, Jan Barciszewski |
| Edizione | [1st ed. 2021.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021 |
| Descrizione fisica | 1 online resource (X, 632 p. 90 illus., 84 illus. in color.) |
| Disciplina | 572.865 |
| Collana | RNA Technologies |
| Soggetto topico |
Epigenetics
RNA - Metabolism Biochemistry Bioinformatics RNA Metabolism Biological Chemistry Transcripció genètica Epigenètica |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-71612-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Epitranscriptomic Modifications and How to Find them -- Epitranscriptomic Signature in Neural Development and Disease -- The Emerging Neuroepitranscriptome -- Epitranscriptomics and Diseases -- Epitranscriptomic Marks and Systems Involved in Gene Regulation, Development and Disease -- Experimental Approaches and Computational Workflows for Systematic Mapping and Functional Interpretation of RNA Modifications -- RNA Modifications: The Mediator Between Cellular Stresses and Biological Effects -- Computational Prediction and Experimental Validation of Specific Modified RNA Sites -- Regulation of RNA Stability Utilizing RNA Modification -- Dynamic RNA Modification Upon Extracellular Stimulus -- RNA Methylation in Cancer -- Regulation of RNA Methylation yy TET Enzymes -- RNA N6-Methyladenosine and G-Quadruplex Structures in Bacteria -- RNA N6-Methyladenosine Chemical Modification as a Therapeutic Target -- Cap-Adjacent m6Am and its Effects On mRNA -- N6-Methyladenosine in The Heart -- The m6a RNA Methylation Regulates Oncogenic Signaling Pathways Driving Cell Transformation and Carcinogenesis -- Psivar: A Database of Functional Variants Involved in Pseudouridylation (Ψ) with Implications for Disease Pathogenesis -- C-to-U RNA Editing by Mammalian APOBEC Enzymes -- The Powerful Mechanism of RNA Editing and its Therapeutic Potentials -- Noncanonical Caps in RNA -- Mass Spectrometry-Based Methods for Characterization of Hypomodifications in tRNA -- Dynamic mRNA Modifications in Plants -- The Mammalian Mitochondrial Epitranscriptome -- Epitranscriptomics Modifications of Micrornas: Classes, Detection, Impact on their Functionality and Next Frontiers -- “Look Before You Leap” when Editing the Introns, or the Secrets Behind the Intronic Post-Transcriptional Modification -- Functional Links Between the Internal N6-Methyl Adenosine Modifications in mRNAs and Human Diseases -- RNA Modifications in Neurodevelopment and Neurodegenerations -- Conventional and Advanced Techniques for Methyl-6-Adenosine Modification Mapping in Transcripts -- Mechanisms and Therapeutic Applications of RNA-Guided RNA Pseudouridylation -- Epitranscriptomic Modifications in lnRNA and miRNA in Cancer and Other Diseases -- RNA m6A and Adipogenesis. |
| Record Nr. | UNINA-9910495228803321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Modified Nucleic Acids in Biology and Medicine / / edited by Stefan Jurga, Volker A. Erdmann (Deceased), Jan Barciszewski
| Modified Nucleic Acids in Biology and Medicine / / edited by Stefan Jurga, Volker A. Erdmann (Deceased), Jan Barciszewski |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (XIV, 453 p. 122 illus., 46 illus. in color.) |
| Disciplina | 547.596 |
| Collana | RNA Technologies |
| Soggetto topico |
Medical genetics
Biomaterials Nucleic acids Medicine - Research Biology - Research Biotechnology Medical Genetics Nucleic Acid Biomedical Research |
| ISBN | 3-319-34175-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Transfer RNA Modifications: from Biological Functions to Biomedical Applications -- Regulated tRNA Cleavage in Biology and Medicine: Roles of tRNA Modifications -- Sulfur-Modifications in tRNA: Function and Implications for Human Disease -- Regulation of Protein Synthesis via the Network Between Modified Nucleotides in tRNA and tRNA Modification Enzymes in Thermus thermophilus, Athermophilic Eubacterium -- Post-Transcriptional Modifications of RNA: Impact on RNA Function and Human Health -- RNA Modification N6-methyladenosine in Post-Transcriptional Regulation -- 8-Hydroxyguanine, an Oxidative DNA and RNA Modification -- Methods for Determination of 2’-O-Me in RNA -- DiadenosineTetraphosphate (Ap4A), in Health and Disease -- Thinking Small: Circulating MicroRNAs as Novel Biomarkers for Diagnosis, Prognosis and Treatment Monitoring in Breast Cancer -- Modified Antisense Oligonucleotides and their Analogs in Therapy of Neuromuscular Diseases -- Effect of Depurination on Cellular and Viral RNA -- Recognition of RNA Sequence and Structure by Duplex and Triplex Formation: Targeting miRNA and pre-miRNA -- Modifications in Therapeutic Oligonucleotides Improving the Delivery -- Interstrand Cross-Linking of Nucleic Acids: from History Towards Recent and Future Applications -- Chemical Synthesis of Lesion-Containing Oligonucleotides for DNA-Repair Studies -- Single-Molecule Visualization of Biomolecules in the Designed DNA Origami Nanostructures Using High-Speed Atomic Force Microscopy -- Polymerase Reactions that Involve Modified Nucleotides. |
| Record Nr. | UNINA-9910253906303321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Plant Epigenetics / / edited by Nikolaus Rajewsky, Stefan Jurga, Jan Barciszewski
| Plant Epigenetics / / edited by Nikolaus Rajewsky, Stefan Jurga, Jan Barciszewski |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (XI, 536 p. 53 illus., 48 illus. in color.) |
| Disciplina | 581.15 |
| Collana | RNA Technologies |
| Soggetto topico |
Nucleic acids
Plant genetics Agriculture Biomedical engineering Biotechnology Nucleic Acid Chemistry Plant Genetics and Genomics Biomedical Engineering/Biotechnology |
| ISBN | 3-319-55520-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1: Conservation, Divergence and Abundance of MiRNAs and Their Effect in Plants -- Chapter 2: The Role of MiRNAs in Auxin Signaling and Regulation During Plant Development -- Chapter 3: Growing Diversity of Plant MicroRNAs and MIR-Derived Small RNAs -- Chapter 4: An Evolutionary View of the Biogenesis and Function of Rice Small RNAs -- Chapter 5: Small RNAs: Master regulators of epigenetic silencing in plants -- Chapter 6: Small RNA biogenesis and degradation in plants -- Chapter 7: Plant Epigenetics: Non-Coding RNAs as Emerging Regulators -- Chapter 8: Genome-Wide Function Analysis of LincRNAs as MiRNA Targets or Decoys in Plant -- Chapter 9: Plant Noncoding RNAs and the New Paradigms -- Chapter 10: Epigenetic Regulation by Non-Coding RNAs in Plant Development -- Chapter 11: RNAi Suppressors: Biology and Mechanisms -- Chapter 12: Analysis of Nucleic Acids Methylation in Plants -- Chapter 13: DNA Methylation in Plants by MicroRNAs -- Chapter 14: DNA Methylation in Plants and its Implications in Development, Hybrid Vigor and Evolution -- Chapter 15: Dynamic DNA Methylation Patterns in Stress Response -- Chapter 16: Locus-specific DNA methylation analysis and applications to plants -- Chapter 17: Epigenetics in Plant Reproductive Development: An Overview from Flowers to Seeds -- Chapter 18: Epigenetic Regulation of Phase Transitions in Arabidopsis thaliana -- Chapter 19: Epigenetics in Plant-Pathogen Interactions -- Chapter 20: Epigenetic Reprogramming During Plant Reproduction -- Chapter 21: Rice Epigenomics: how does Epigenetic Manipulation of Crops Contribute to Agriculture? -- Chapter 22: Epigenetic Characterization of Satellite DNA in Sugar Beet (Beta vulgaris) -- Chapter 23: Universal and Lineage-specific Properties of Linker Histones and SWI/SNF-chromatin Remodeling Complexes in Plants -- Chapter 24: Abiotic Stress Induced Epigenetic Modifications in Plants: How Much do we Know? -- Chapter 25: Apple Latent Spherical Virus (ALSV) Vector as a Tool for Reverse Genetic Studies and Non-Transgenic Breeding of a Variety of Crops. |
| Record Nr. | UNINA-9910253929203321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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RNA and DNA Diagnostics / / edited by Volker A. Erdmann, Stefan Jurga, Jan Barciszewski
| RNA and DNA Diagnostics / / edited by Volker A. Erdmann, Stefan Jurga, Jan Barciszewski |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (353 p.) |
| Disciplina | 572.88 |
| Collana | RNA Technologies |
| Soggetto topico |
Medical genetics
Biomaterials Nucleic acids Medicine - Research Biology - Research Biotechnology Medical Genetics Nucleic Acid Biomedical Research |
| ISBN | 3-319-17305-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Electrochemical Biosensors for miRNA Detection -- Electrochemical Detection of RNA.- DNA and PNA probes for DNA Detection in Electroanalytical Systems -- DNA for Non-Nucleic Acid Sensing -- Aptamers in Oncotherapy -- Genotyping of Single Nucleotide Polymorphism -- Environmentally Responsive and Bright Fluorescent Probes Possessing Dansyl-modified Oligonucleotides under Hybridization of DNA and RNA -- Fluorescent Nucleic Acid Analogues in Research and Clinical Diagnostics -- Emergent Properties and Functions of Nanoconfined Nucleic Acid Architectures -- RNA and DNA Diagnostics on Microspheres: Current and Emerging Methods -- DNA and RNA Electronic Properties for Molecular Modifications and Environmental State Diagnostics -- Mechanochemical Sensing.- Microarrays as Research Tools and Diagnostic Devices -- Quadruplex Priming Amplification (QPA) for Nucleic Acid Diagnostics.- Single-molecule strategies for DNA and RNA diagnostics -- Detection and Assessment of microRNA Expression in Human Disease. |
| Record Nr. | UNINA-9910298265103321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Systems Biology / / edited by Nikolaus Rajewsky, Stefan Jurga, Jan Barciszewski
| Systems Biology / / edited by Nikolaus Rajewsky, Stefan Jurga, Jan Barciszewski |
| Edizione | [1st ed. 2018.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
| Descrizione fisica | 1 online resource (404 pages) |
| Disciplina | 570.113 |
| Collana | RNA Technologies |
| Soggetto topico |
Bioinformatics
Medical genetics Medicine - Research Biology - Research Biomaterials Nucleic acids Biotechnology Computational and Systems Biology Medical Genetics Biomedical Research Nucleic Acid |
| ISBN | 3-319-92967-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1: Systems Biology of Genome Structure and Dynamics -- Chapter 2: A Systems Perspective of Complex Diseases: from Reductionism to Integration -- Chapter 3: Systems Biology of Bacterial Immune Systems: Regulation of Restriction-Modification and CRISPR-Cas Systems -- Chapter 4: Systems Biology of RNA Binding Proteins in Amyotrophic Lateral Sclerosis -- Chapter 5: Systems Approaches to Map in vivo RNA-Protein Interactions in Arabidopsis thaliana -- Chapter 6: Systems-Level Analysis of Bacterial Regulatory Small RNA Networks -- Chapter 7: Epioncogenes in Cancer—Identification of Transcriptomic and Epigenomic Cooperation Networks by Multi-Omics Integration of RNA-Seq and ChIP-Seqdata -- Chapter 8: Coupling Large Scale –Omics Data for Deciphering Systems Complexity -- Chapter 9: Deciphering the Universe of RNA Structures and tTans RNA-RNA Interactions of Transcriptomes in vivo / from Experimental Protocols to Computational Analyses -- Chapter 10: Is Autogenous Post-Transcriptional Gene Regulation Common? -- Chapter 11: The Interplay of Non-Coding RNAs and X Chromosome Inactivation in Human Disease -- Chapter 12: Novel Insights of the Gene Translational Dynamic and Complex Revealed by Ribosome Profiling -- Chapter 13: Biophysical Analysis of MiRNA-Dependent Gene Regulation -- Chapter 14: Modeling and Analyzing the Flow of Molecular Machines in Gene Expression -- Chapter 15: Robust Approaches to Generating Reliable Predictive Models in Systems Biology -- Chapter 16: Hints from Information Theory for Analyzing Dynamic & High Dimensional Biological Data -- Chapter 17: Enhancing Metabolic Models with Genome-Scale Experimental Data -- Chapter 18: An Integrative MuSiCO Algorithm: from the Patient-Specific Transcriptional Profiles to Novel Checkpoints in Disease Pathobiology -- Chapter 19: Nanocellulose: a New Multifunctional Tool for RNA System Biology Research. |
| Record Nr. | UNINA-9910298403203321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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