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Single molecule dynamics in life science [[electronic resource] /] / edited by Toshio Yanagida and Yoshiharu Ishii
| Single molecule dynamics in life science [[electronic resource] /] / edited by Toshio Yanagida and Yoshiharu Ishii |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2009 |
| Descrizione fisica | 1 online resource (348 p.) |
| Disciplina |
572.6
572.8 |
| Altri autori (Persone) |
YanagidaToshio
IshiiYoshiharu |
| Soggetto topico |
Biology
Molecules |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-282-02540-6
9786612025402 3-527-62613-1 3-527-62614-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Single Molecule Dynamics in Life Science; Contents; Preface; List of Contributors; 1 A Road Map to Single Molecule Dynamics; 1.1 Visualization of Single Molecules; 1.2 Single Molecule Position Tracking; 1.3 Single Molecules in Live Cells; 1.4 Fluorescence Spectroscopy and Biomolecular Dynamics; 1.5 Single Molecule Manipulation and Molecular Motors; 1.6 Mechano-Chemical Coupling of Molecular Motors; 1.7 DNA-Based Motors; 1.8 Imaging with AFM and Force Measurements; References; 2 Single Molecule Study for Elucidating the Mechanism Used by Biosystems to Utilize Thermal Fluctuations
2.1 Introduction2.1.1 Differences between Man-Made and Biological Molecular Machines; 2.1.2 Single Molecule Imaging and Nano-Detection; 2.2 Simultaneous Measurements of Individual ATP Hydrolysis Cycles and Mechanical Events by a Myosin Motor; 2.2.1 ATP Hydrolysis Cycles; 2.2.2 Mechanical Events; 2.2.3 Simultaneous Measurements; 2.3 Resolving the Process of a Displacement by Scanning Probe Nanometry; 2.3.1 Observation and Manipulation of a Single Myosin Motor; 2.3.2 Displacements; 2.3.3 Sub-steps within a Displacement; 2.3.4 Nature of Sub-steps 2.3.5 Comparing the Actions of Individual Myosin Motors with those of Muscle2.3.6 Other Types of Molecular Motors; 2.4 Biased Brownian Step Model; 2.4.1 Asymmetric Potential; 2.4.2 Comparison with Other Studies; 2.4.3 Computer Simulation: from a Single Molecular Motor to Muscle; 2.5 Conclusion for the Unique Mechanism of Biological Molecular Machines; References; 3 Imaging and Molecular Motors; 3.1 Introduction; 3.2 Methods; 3.2.1 Detection of Single Fluorophores; 3.2.2 Sub-Diffraction Localization of Fluorescent Molecules; 3.2.3 Darkfield Imaging with One Nanometer Accuracy (DIONA) 3.2.4 Single-molecule High Resolution Imaging with Photobleaching (SHRImP)3.2.5 Single Molecule Fluorescence Resonance Energy Transfer (smFRET); 3.2.6 Orientation of Single Molecules; 3.2.7 Polarized Total Internal Reection Fluorescence Microscopy (polTIRF); 3.2.8 Defocused Orientational and Positional Imaging (DOPI); 3.3 Molecular Motors; 3.3.1 Myosin V; 3.3.2 Myosin II; 3.3.3 Myosin VI; 3.3.4 Conventional Kinesin; 3.3.5 Other Kinesins; 3.3.6 Dyneins; 3.3.7 Single Molecule Intracellular Imaging; 3.4 Conclusions; References; 4 Ion Channels; 4.1 Introduction; 4.2 Articial Bilayers 4.2.1 Solid Supported Bilayers4.2.2 Self-Standing Bilayers; 4.3 Simultaneous Optical and Electrical Recording of the Single BK-Channels; 4.4 Detection of Channel Conformational Change; 4.5 ''Optical Patch-Clamping''; 4.6 Conclusion; References; 5 Signal Transduction across the Plasma Membrane; 5.1 Introduction; 5.2 Signal Transduction Mediated by Receptor Tyrosine Kinase; 5.3 Association between EGF and EGFR and Formation of the Signaling Dimers of EGFR; 5.4 Amplication and Propagation of EGFR Activation; 5.5 Dynamics of the NGF/NGFR Complex 5.6 Stochastic Signal Processing and Transduction in Living Cells |
| Record Nr. | UNINA-9910145250703321 |
| Weinheim, : Wiley-VCH, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Single molecule dynamics in life science [[electronic resource] /] / edited by Toshio Yanagida and Yoshiharu Ishii
| Single molecule dynamics in life science [[electronic resource] /] / edited by Toshio Yanagida and Yoshiharu Ishii |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2009 |
| Descrizione fisica | 1 online resource (348 p.) |
| Disciplina |
572.6
572.8 |
| Altri autori (Persone) |
YanagidaToshio
IshiiYoshiharu |
| Soggetto topico |
Biology
Molecules |
| ISBN |
1-282-02540-6
9786612025402 3-527-62613-1 3-527-62614-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Single Molecule Dynamics in Life Science; Contents; Preface; List of Contributors; 1 A Road Map to Single Molecule Dynamics; 1.1 Visualization of Single Molecules; 1.2 Single Molecule Position Tracking; 1.3 Single Molecules in Live Cells; 1.4 Fluorescence Spectroscopy and Biomolecular Dynamics; 1.5 Single Molecule Manipulation and Molecular Motors; 1.6 Mechano-Chemical Coupling of Molecular Motors; 1.7 DNA-Based Motors; 1.8 Imaging with AFM and Force Measurements; References; 2 Single Molecule Study for Elucidating the Mechanism Used by Biosystems to Utilize Thermal Fluctuations
2.1 Introduction2.1.1 Differences between Man-Made and Biological Molecular Machines; 2.1.2 Single Molecule Imaging and Nano-Detection; 2.2 Simultaneous Measurements of Individual ATP Hydrolysis Cycles and Mechanical Events by a Myosin Motor; 2.2.1 ATP Hydrolysis Cycles; 2.2.2 Mechanical Events; 2.2.3 Simultaneous Measurements; 2.3 Resolving the Process of a Displacement by Scanning Probe Nanometry; 2.3.1 Observation and Manipulation of a Single Myosin Motor; 2.3.2 Displacements; 2.3.3 Sub-steps within a Displacement; 2.3.4 Nature of Sub-steps 2.3.5 Comparing the Actions of Individual Myosin Motors with those of Muscle2.3.6 Other Types of Molecular Motors; 2.4 Biased Brownian Step Model; 2.4.1 Asymmetric Potential; 2.4.2 Comparison with Other Studies; 2.4.3 Computer Simulation: from a Single Molecular Motor to Muscle; 2.5 Conclusion for the Unique Mechanism of Biological Molecular Machines; References; 3 Imaging and Molecular Motors; 3.1 Introduction; 3.2 Methods; 3.2.1 Detection of Single Fluorophores; 3.2.2 Sub-Diffraction Localization of Fluorescent Molecules; 3.2.3 Darkfield Imaging with One Nanometer Accuracy (DIONA) 3.2.4 Single-molecule High Resolution Imaging with Photobleaching (SHRImP)3.2.5 Single Molecule Fluorescence Resonance Energy Transfer (smFRET); 3.2.6 Orientation of Single Molecules; 3.2.7 Polarized Total Internal Reection Fluorescence Microscopy (polTIRF); 3.2.8 Defocused Orientational and Positional Imaging (DOPI); 3.3 Molecular Motors; 3.3.1 Myosin V; 3.3.2 Myosin II; 3.3.3 Myosin VI; 3.3.4 Conventional Kinesin; 3.3.5 Other Kinesins; 3.3.6 Dyneins; 3.3.7 Single Molecule Intracellular Imaging; 3.4 Conclusions; References; 4 Ion Channels; 4.1 Introduction; 4.2 Articial Bilayers 4.2.1 Solid Supported Bilayers4.2.2 Self-Standing Bilayers; 4.3 Simultaneous Optical and Electrical Recording of the Single BK-Channels; 4.4 Detection of Channel Conformational Change; 4.5 ''Optical Patch-Clamping''; 4.6 Conclusion; References; 5 Signal Transduction across the Plasma Membrane; 5.1 Introduction; 5.2 Signal Transduction Mediated by Receptor Tyrosine Kinase; 5.3 Association between EGF and EGFR and Formation of the Signaling Dimers of EGFR; 5.4 Amplication and Propagation of EGFR Activation; 5.5 Dynamics of the NGF/NGFR Complex 5.6 Stochastic Signal Processing and Transduction in Living Cells |
| Record Nr. | UNINA-9910830701503321 |
| Weinheim, : Wiley-VCH, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Single molecule dynamics in life science [[electronic resource] /] / edited by Toshio Yanagida and Yoshiharu Ishii
| Single molecule dynamics in life science [[electronic resource] /] / edited by Toshio Yanagida and Yoshiharu Ishii |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2009 |
| Descrizione fisica | 1 online resource (348 p.) |
| Disciplina |
572.6
572.8 |
| Altri autori (Persone) |
YanagidaToshio
IshiiYoshiharu |
| Soggetto topico |
Biology
Molecules |
| ISBN |
1-282-02540-6
9786612025402 3-527-62613-1 3-527-62614-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Single Molecule Dynamics in Life Science; Contents; Preface; List of Contributors; 1 A Road Map to Single Molecule Dynamics; 1.1 Visualization of Single Molecules; 1.2 Single Molecule Position Tracking; 1.3 Single Molecules in Live Cells; 1.4 Fluorescence Spectroscopy and Biomolecular Dynamics; 1.5 Single Molecule Manipulation and Molecular Motors; 1.6 Mechano-Chemical Coupling of Molecular Motors; 1.7 DNA-Based Motors; 1.8 Imaging with AFM and Force Measurements; References; 2 Single Molecule Study for Elucidating the Mechanism Used by Biosystems to Utilize Thermal Fluctuations
2.1 Introduction2.1.1 Differences between Man-Made and Biological Molecular Machines; 2.1.2 Single Molecule Imaging and Nano-Detection; 2.2 Simultaneous Measurements of Individual ATP Hydrolysis Cycles and Mechanical Events by a Myosin Motor; 2.2.1 ATP Hydrolysis Cycles; 2.2.2 Mechanical Events; 2.2.3 Simultaneous Measurements; 2.3 Resolving the Process of a Displacement by Scanning Probe Nanometry; 2.3.1 Observation and Manipulation of a Single Myosin Motor; 2.3.2 Displacements; 2.3.3 Sub-steps within a Displacement; 2.3.4 Nature of Sub-steps 2.3.5 Comparing the Actions of Individual Myosin Motors with those of Muscle2.3.6 Other Types of Molecular Motors; 2.4 Biased Brownian Step Model; 2.4.1 Asymmetric Potential; 2.4.2 Comparison with Other Studies; 2.4.3 Computer Simulation: from a Single Molecular Motor to Muscle; 2.5 Conclusion for the Unique Mechanism of Biological Molecular Machines; References; 3 Imaging and Molecular Motors; 3.1 Introduction; 3.2 Methods; 3.2.1 Detection of Single Fluorophores; 3.2.2 Sub-Diffraction Localization of Fluorescent Molecules; 3.2.3 Darkfield Imaging with One Nanometer Accuracy (DIONA) 3.2.4 Single-molecule High Resolution Imaging with Photobleaching (SHRImP)3.2.5 Single Molecule Fluorescence Resonance Energy Transfer (smFRET); 3.2.6 Orientation of Single Molecules; 3.2.7 Polarized Total Internal Reection Fluorescence Microscopy (polTIRF); 3.2.8 Defocused Orientational and Positional Imaging (DOPI); 3.3 Molecular Motors; 3.3.1 Myosin V; 3.3.2 Myosin II; 3.3.3 Myosin VI; 3.3.4 Conventional Kinesin; 3.3.5 Other Kinesins; 3.3.6 Dyneins; 3.3.7 Single Molecule Intracellular Imaging; 3.4 Conclusions; References; 4 Ion Channels; 4.1 Introduction; 4.2 Articial Bilayers 4.2.1 Solid Supported Bilayers4.2.2 Self-Standing Bilayers; 4.3 Simultaneous Optical and Electrical Recording of the Single BK-Channels; 4.4 Detection of Channel Conformational Change; 4.5 ''Optical Patch-Clamping''; 4.6 Conclusion; References; 5 Signal Transduction across the Plasma Membrane; 5.1 Introduction; 5.2 Signal Transduction Mediated by Receptor Tyrosine Kinase; 5.3 Association between EGF and EGFR and Formation of the Signaling Dimers of EGFR; 5.4 Amplication and Propagation of EGFR Activation; 5.5 Dynamics of the NGF/NGFR Complex 5.6 Stochastic Signal Processing and Transduction in Living Cells |
| Record Nr. | UNINA-9910841236203321 |
| Weinheim, : Wiley-VCH, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||