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Bioactive compounds from marine foods : plant and animal sources / / edited by Blanca Hernández-Ledesma and Miguel Herrero
| Bioactive compounds from marine foods : plant and animal sources / / edited by Blanca Hernández-Ledesma and Miguel Herrero |
| Autore | Hernández-Ledesma Blanca |
| Pubbl/distr/stampa | Chichester, West Sussex : , : John Wiley & Sons Inc., , 2014 |
| Descrizione fisica | 1 online resource (467 p.) |
| Disciplina | 615.3/21 |
| Altri autori (Persone) |
Hernandez-LedesmaBlanca
HerreroMiguel |
| Collana | IFT Press series |
| Soggetto topico |
Pharmacognosy
Marine pharmacology Materia medica, Vegetable Natural products - Therapeutic use Bioactive compounds |
| ISBN |
1-118-41287-7
1-118-41289-3 1-118-41286-9 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Bioactive Compounds from Marine Foods; Contents; List of Contributors; 1 An Update on the Biomedical Prospects of Marine-derived Small Molecules with Fascinating Atom and Stereochemical Diversity; 1.1 Introduction; 1.1.1 Overview of known compounds, highlighting molecules of significance; 1.1.1.1 Clinical candidates and MDSM chemical probes; 1.1.2 Selected important marine sources of MDSMs; 1.1.2.1 Macroorganisms: an analysis of their critical role; 1.1.2.2 Microorganisms: questions about their being the actual source; 1.1.3 Highlights of MDSMs of therapeutic potential; 1.1.3.1 Terpene
1.1.3.2 Polyketide1.1.3.3 Alkaloid; 1.1.3.4 Depsipeptide; 1.1.3.5 Polyketide-peptide; 1.1.4 New insights and lessons that address supply challenges; 1.2 A view based on atom diversity; 1.2.1 Terpene; 1.2.2 Polyketide; 1.2.3 Alkaloid; 1.2.4 Depsipeptide; 1.2.5 Polyketide-peptide; 1.3 A view based on stereochemical diversity; 1.3.1 Terpene; 1.3.2 Polyketide; 1.3.3 Alkaloid; 1.3.4 Depsipeptide; 1.3.5 Polyketide-peptide; 1.4 Case studies of chemical probes and chemical probes in the therapeutic discovery pipeline; 1.5 Conclusion; Acknowledgments; References 2 Antihypertensive Peptides from Marine Sources2.1 Introduction; 2.2 Marine antihypertensive peptides and blood pressure control; 2.3 Generation of marine antihypertensive peptides; 2.4 Structure-activity relationships; 2.5 Bioavailability; 2.6 In vivo animal studies; 2.7 In vivo human studies; 2.8 Marine peptides as antihypertensive ingredients; 2.9 Conclusion; Acknowledgments; References; 3 Bioactive Peptides from Marine Processing Byproducts; 3.1 Introduction; 3.2 Fish muscle proteins: precursors of fish bioactive peptides; 3.3 Fish meal production; 3.4 Fish silage production 3.5 Traditional fermented fish protein products3.6 Strategies for the generation of bioactive peptides from marine byproducts; 3.6.1 Marine-derived peptides and human health; 3.6.1.1 Marine-derived peptides in the physiological control and maintenance of blood pressure: renin and ACE-I; 3.6.1.2 Antimicrobial peptides from marine sources and byproducts; 3.6.1.3 Antioxidant peptides from marine byproducts; 3.6.2 Membrane processing and the future for marine-derived bioactive peptide products; 3.7 Conclusion; Acknowledgments; References; 4 Development of Marine Peptides as Anticancer Agents 4.1 Introduction4.2 Peptides that induce apoptosis; 4.2.1 Peptides that activate the intrinsic mitochondrial pathway; 4.2.2 Peptides that target the JNK or p38 MAPK pathways; 4.2.3 Marine peptides that target the PI3K/AKT pathway; 4.2.4 Peptides without a known mechanism for their apoptosis-inducing activity; 4.3 Peptides that affect the tubulin-microtubule equilibrium; 4.4 Peptides that inhibit angiogenesis; 4.5 Peptides without a known mechanism for their antitumor activity; 4.6 Conclusion; Acknowledgments; References; 5 Using Marine Cryptides against Metabolic Syndrome 5.1 Marine cryptides |
| Record Nr. | UNINA-9910139000103321 |
Hernández-Ledesma Blanca
|
||
| Chichester, West Sussex : , : John Wiley & Sons Inc., , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Bioactive compounds from marine foods : plant and animal sources / / edited by Blanca Hernández-Ledesma and Miguel Herrero
| Bioactive compounds from marine foods : plant and animal sources / / edited by Blanca Hernández-Ledesma and Miguel Herrero |
| Autore | Hernández-Ledesma Blanca |
| Pubbl/distr/stampa | Chichester, West Sussex : , : John Wiley & Sons Inc., , 2014 |
| Descrizione fisica | 1 online resource (467 p.) |
| Disciplina | 615.3/21 |
| Altri autori (Persone) |
Hernandez-LedesmaBlanca
HerreroMiguel |
| Collana | IFT Press series |
| Soggetto topico |
Pharmacognosy
Marine pharmacology Materia medica, Vegetable Natural products - Therapeutic use Bioactive compounds |
| ISBN |
1-118-41287-7
1-118-41289-3 1-118-41286-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Bioactive Compounds from Marine Foods; Contents; List of Contributors; 1 An Update on the Biomedical Prospects of Marine-derived Small Molecules with Fascinating Atom and Stereochemical Diversity; 1.1 Introduction; 1.1.1 Overview of known compounds, highlighting molecules of significance; 1.1.1.1 Clinical candidates and MDSM chemical probes; 1.1.2 Selected important marine sources of MDSMs; 1.1.2.1 Macroorganisms: an analysis of their critical role; 1.1.2.2 Microorganisms: questions about their being the actual source; 1.1.3 Highlights of MDSMs of therapeutic potential; 1.1.3.1 Terpene
1.1.3.2 Polyketide1.1.3.3 Alkaloid; 1.1.3.4 Depsipeptide; 1.1.3.5 Polyketide-peptide; 1.1.4 New insights and lessons that address supply challenges; 1.2 A view based on atom diversity; 1.2.1 Terpene; 1.2.2 Polyketide; 1.2.3 Alkaloid; 1.2.4 Depsipeptide; 1.2.5 Polyketide-peptide; 1.3 A view based on stereochemical diversity; 1.3.1 Terpene; 1.3.2 Polyketide; 1.3.3 Alkaloid; 1.3.4 Depsipeptide; 1.3.5 Polyketide-peptide; 1.4 Case studies of chemical probes and chemical probes in the therapeutic discovery pipeline; 1.5 Conclusion; Acknowledgments; References 2 Antihypertensive Peptides from Marine Sources2.1 Introduction; 2.2 Marine antihypertensive peptides and blood pressure control; 2.3 Generation of marine antihypertensive peptides; 2.4 Structure-activity relationships; 2.5 Bioavailability; 2.6 In vivo animal studies; 2.7 In vivo human studies; 2.8 Marine peptides as antihypertensive ingredients; 2.9 Conclusion; Acknowledgments; References; 3 Bioactive Peptides from Marine Processing Byproducts; 3.1 Introduction; 3.2 Fish muscle proteins: precursors of fish bioactive peptides; 3.3 Fish meal production; 3.4 Fish silage production 3.5 Traditional fermented fish protein products3.6 Strategies for the generation of bioactive peptides from marine byproducts; 3.6.1 Marine-derived peptides and human health; 3.6.1.1 Marine-derived peptides in the physiological control and maintenance of blood pressure: renin and ACE-I; 3.6.1.2 Antimicrobial peptides from marine sources and byproducts; 3.6.1.3 Antioxidant peptides from marine byproducts; 3.6.2 Membrane processing and the future for marine-derived bioactive peptide products; 3.7 Conclusion; Acknowledgments; References; 4 Development of Marine Peptides as Anticancer Agents 4.1 Introduction4.2 Peptides that induce apoptosis; 4.2.1 Peptides that activate the intrinsic mitochondrial pathway; 4.2.2 Peptides that target the JNK or p38 MAPK pathways; 4.2.3 Marine peptides that target the PI3K/AKT pathway; 4.2.4 Peptides without a known mechanism for their apoptosis-inducing activity; 4.3 Peptides that affect the tubulin-microtubule equilibrium; 4.4 Peptides that inhibit angiogenesis; 4.5 Peptides without a known mechanism for their antitumor activity; 4.6 Conclusion; Acknowledgments; References; 5 Using Marine Cryptides against Metabolic Syndrome 5.1 Marine cryptides |
| Record Nr. | UNINA-9910819805403321 |
|
Hernández-Ledesma Blanca
|
||
| Chichester, West Sussex : , : John Wiley & Sons Inc., , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Peptides for Health Benefits 2019 : Volume 2
| Peptides for Health Benefits 2019 : Volume 2 |
| Autore | Hernández-Ledesma Blanca |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (342 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
antihypertensive peptides
functional food food-derived fermentation Chlorella sorokiniana in silico BIOPEP-UWM database proteomics bioactive peptides nano liquid chromatography tandem mass spectrometry (nanoLC-nanoESI MS/MS) apolipoprotein E amyloid fibrils Alzheimer's disease Αβ oligomer amyloid Aβ peptide glioma platelets antiproliferative assay conjugation docetaxel doxorubicin extra domain B fibronectin Fmoc/tBu peptide-drug conjugate prostate cancer solid-phase synthesis targeting acrylamide enteric nervous system galanin pig stomach formyl peptide receptors ligands diseases polymicrobial biofilms intragenic antimicrobial peptide Hs02 Pseudomonas aeruginosa Staphylococcus aureus osteostatin arthritis inflammation immune response cartilage destruction bone erosion collagen hydrolysis enzyme molecular weight sheepskin NF-κB dry-cured pork ham angiotensin I converting enzyme endothelial dysfunction molecular blind docking Lactoferricin B (Lfcin B) Histatin-5 antimicrobial peptides (AMPs) antifungal activity proteome microarray synergy temporin MRSA antimicrobial peptide human keratinocytes pseudin-2 antisepsis, peptide antibiotics neurotensin asthma T cells In situ tetramer staining MHC tetramer antigen-specific confocal microscopy fresh tissue velvet antler alcalase hydrolysate antioxidant peptide protection ability oxidative stress Crassostrea angulata pidotimod CXCR3 monocyte migration PI3K/Akt pathway T cell immunomodulant host defense peptides membrane activity copper piscidins Clostridioides difficile prolactin-releasing peptide GPR10 RF-amide peptides food intake regulation energy expenditure neuroprotection signaling gender differences dyslipidemia obesity hyperglycemia pulmonary emphysema endothelial progenitor cells angiogenic precursor cells pegylated glucagon-like peptide 1 and endothelial regeneration miiuy croaker (Miichthys miiuy) swim bladder FPYLRH antioxidant activity cytoprotective effect antimicrobial peptides antimicrobial resistance AMP identification and design biosynthesis mode of action physico-chemical properties therapeutic potential insects Cecropins Cec-analogs MDR infectious diseases airway inflammation non-atopic asthma hybrid peptide pro-inflammatory cytokines sPLA2 MDA database proteolysis SMILES code foods nutrition chronic diseases nutraceuticals peptide vaccine immune checkpoint inhibitor humanized mouse cancer antigen immune suppression vasoactive intestinal peptide VPAC1 receptor VPAC2 receptor rheumatic diseases inflammatory bowel disease central nervous system diseases type 1 diabetes Sjögren's syndrome biomarkers human antimicrobial peptides defensins cathelicidins anti-inflammatory pro-inflammatory peptide combinatorial library library design screening mutagenesis prolyl-hydroxyproline (Pro-Hyp) hydroxyprolyl-glycine (Hyp-Gly) collagen peptide fibroblasts fetal bovine serum (FBS) AMD CNV VEGFR1 multimeric peptides oral delivery colorectal cancer cancer stem cells chemoprevention bioactive peptide lunasin ACE-inhibitory activity whey peptides molecular docking hypertension antibiotic resistance cystic fibrosis cryptides anti-biofilm peptides synergistic effects |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Peptides for Health Benefits 2019 |
| Record Nr. | UNINA-9910557492903321 |
|
Hernández-Ledesma Blanca
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Peptides for Health Benefits 2019 : Volume 1
| Peptides for Health Benefits 2019 : Volume 1 |
| Autore | Hernández-Ledesma Blanca |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (340 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
antihypertensive peptides
functional food food-derived fermentation Chlorella sorokiniana in silico BIOPEP-UWM database proteomics bioactive peptides nano liquid chromatography tandem mass spectrometry (nanoLC-nanoESI MS/MS) apolipoprotein E amyloid fibrils Alzheimer's disease Αβ oligomer amyloid Aβ peptide glioma platelets antiproliferative assay conjugation docetaxel doxorubicin extra domain B fibronectin Fmoc/tBu peptide-drug conjugate prostate cancer solid-phase synthesis targeting acrylamide enteric nervous system galanin pig stomach formyl peptide receptors ligands diseases polymicrobial biofilms intragenic antimicrobial peptide Hs02 Pseudomonas aeruginosa Staphylococcus aureus osteostatin arthritis inflammation immune response cartilage destruction bone erosion collagen hydrolysis enzyme molecular weight sheepskin NF-κB dry-cured pork ham angiotensin I converting enzyme endothelial dysfunction molecular blind docking Lactoferricin B (Lfcin B) Histatin-5 antimicrobial peptides (AMPs) antifungal activity proteome microarray synergy temporin MRSA antimicrobial peptide human keratinocytes pseudin-2 antisepsis, peptide antibiotics neurotensin asthma T cells In situ tetramer staining MHC tetramer antigen-specific confocal microscopy fresh tissue velvet antler alcalase hydrolysate antioxidant peptide protection ability oxidative stress Crassostrea angulata pidotimod CXCR3 monocyte migration PI3K/Akt pathway T cell immunomodulant host defense peptides membrane activity copper piscidins Clostridioides difficile prolactin-releasing peptide GPR10 RF-amide peptides food intake regulation energy expenditure neuroprotection signaling gender differences dyslipidemia obesity hyperglycemia pulmonary emphysema endothelial progenitor cells angiogenic precursor cells pegylated glucagon-like peptide 1 and endothelial regeneration miiuy croaker (Miichthys miiuy) swim bladder FPYLRH antioxidant activity cytoprotective effect antimicrobial peptides antimicrobial resistance AMP identification and design biosynthesis mode of action physico-chemical properties therapeutic potential insects Cecropins Cec-analogs MDR infectious diseases airway inflammation non-atopic asthma hybrid peptide pro-inflammatory cytokines sPLA2 MDA database proteolysis SMILES code foods nutrition chronic diseases nutraceuticals peptide vaccine immune checkpoint inhibitor humanized mouse cancer antigen immune suppression vasoactive intestinal peptide VPAC1 receptor VPAC2 receptor rheumatic diseases inflammatory bowel disease central nervous system diseases type 1 diabetes Sjögren's syndrome biomarkers human antimicrobial peptides defensins cathelicidins anti-inflammatory pro-inflammatory peptide combinatorial library library design screening mutagenesis prolyl-hydroxyproline (Pro-Hyp) hydroxyprolyl-glycine (Hyp-Gly) collagen peptide fibroblasts fetal bovine serum (FBS) AMD CNV VEGFR1 multimeric peptides oral delivery colorectal cancer cancer stem cells chemoprevention bioactive peptide lunasin ACE-inhibitory activity whey peptides molecular docking hypertension antibiotic resistance cystic fibrosis cryptides anti-biofilm peptides synergistic effects |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Peptides for Health Benefits 2019 |
| Record Nr. | UNINA-9910557631703321 |
|
Hernández-Ledesma Blanca
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||