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Molecular Biology of Selenium in Health and Disease
| Molecular Biology of Selenium in Health and Disease |
| Autore | Tsuji Petra A |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (384 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
selenoproteome
selenoprotein hierarchy nonradioactive isotopes SEC-ICP MS glutathione peroxidase thioredoxin reductase SECIS translation regulation autoimmune thyroid disease diabetes mellitus Graves' disease Hashimoto thyroiditis infection inflammation long-COVID rheumatoid arthritis selenoprotein P sepsis selenoprotein W thioredoxin 14-3-3 Akt cell death Selenof selenium selenoprotein colon cancer barrier integrity cardiovascular heart selenoproteins Keshan's Disease bacteria selenite selenium delivery system Trsp hypothalamus Agrp neuron sex differences diet-induced obesity leptin resistance macrophage differentiation redox signaling NRF2 NF-κB lipid mediators seleocysteine autoimmunity lymphocyte cadmium cytotoxicity cancer therapy cisplatin ICP-MS nonsynonymous mutation selenium homeostasis ZIP8 Trit1 isopentenylation tRNA[Ser]Sec selenocysteine genetic variance human disease selenophosphate synthetase endothelial cell reactive oxygen species cell growth angiogenesis SEPHS1 early embryogenesis embryonic lethality prostate cancer tumor suppressor selenoprotein deficiency SECISBP2 Sec-tRNA[Ser]Sec SEPSECS antioxidative defense autoantibody Hashimoto's thyroiditis trace element recoding SECIS-binding protein translation termination nonsense-mediated decay ribosome rescue health mouse models selenocysteine (Sec) virus viral antioxidant HIV HCV HBV coxsackie virus influenza HIV-1 viral infection SELENOS SELENOO primary T cells Jurkat SupT1 translational control |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566482103321 |
Tsuji Petra A
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Selenium : Its Molecular Biology and Role in Human Health / / edited by Dolph L. Hatfield, Ulrich Schweizer, Petra A. Tsuji, Vadim N. Gladyshev
| Selenium : Its Molecular Biology and Role in Human Health / / edited by Dolph L. Hatfield, Ulrich Schweizer, Petra A. Tsuji, Vadim N. Gladyshev |
| Edizione | [4th ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (XXXI, 628 p. 88 illus., 59 illus. in color.) |
| Disciplina | 616.079 |
| Soggetto topico |
Immunology
Nutrition Nutrition |
| ISBN | 3-319-41283-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part I. The machinery of selenoprotein biosynthesis -- 1 Selenocysteine tRNA[Ser]Sec: From nonsense suppressor tRNA to the quintessential constituent in selenoprotein biosynthesis -- 2 Eukaryotic mechanisms of selenocysteine translation and its reconstitution in vitro -- 3 Probing selenoprotein translation by ribosome profiling -- 4 Pathways in de novo biosynthesis of selenocysteine and cysteine in eukaryotes -- 5 Prokaryotic selenoprotein biosynthesis and function -- 6 The role of selenium in human evolution -- 7 The chemistry of selenocysteine in proteins -- 8 Evolution of selenophosphate synthetase -- 9 Structure and mechanism of selenocysteine synthases -- 10 Mechanism, structure, and biological role of selenocysteine lyase -- Part II. Selenoproteins, their occurrence and function -- 11 Eukaryotic selenoproteomes -- 12 Prokaryotic selenoproteins and selenoproteomes -- 13 Functional genomics of selenoproteins and Se-responsive pathways -- 14 Selenium regulation of the selenoprotein and non-selenoprotein transcriptomes in a variety of species -- 15 77Se NMR spectroscopy of selenoproteins -- 16 Thioredoxin reductase 1 as an anticancer drug target -- 17 Basics and news on glutathione peroxidases -- 18 Glutathione Peroxidase 4 -- 19 The 15 kDa Selenoprotein: Insights into its regulation and function -- 20 Selenoprotein K and protein palmitoylation in regulating immune cell functions -- 21 Selenoprotein M: Structure, expression and functional relevance -- 22 Selenoprotein P and selenium distribution in mammals -- 23 Selenoprotein T: From discovery to functional studies using conditional knockout mice -- 24 Biochemistry and function of methionine sulfoxide reductase -- Part III. Dietary selenium and its impact on human health -- 25 Selenium: Dietary sources, human nutritional requirements and intake across populations -- 26 Human clinical trials involving selenium -- 27 Status of dietary selenium in cancer prevention -- 28 Selenium in HIV/AIDS -- 29 Genetic variations in the genes for selenoproteins implicate the encoded proteins in cancer etiology -- 30 Is adequate selenium important for healthy human pregnancy? -- 31 The epidemiology of selenium and human health -- 32 Sex-specific differences in biological effects and metabolism of selenium -- 33 Selenium and endocrine tissues -- 34 Selenium antagonism with mercury and arsenic: from chemistry to population health and demography -- 35 Biological selenium species and selenium speciation in biological samples -- 36 Selenoproteins in nervous system development, function and degeneration -- 37 Interplay of selenoproteins and different antioxidant systems in various cancers -- 38 Glutathione peroxidase 2, a selenoprotein exhibiting a dual personality in preventing and promoting cancer -- 39 Selenoproteins in cardiovascular redox pathology -- 40 What do we know about selenium contributions to muscle physiology? -- 41 Tissue-specific regulation of thyroid status by selenodeiodinases -- 42 The role of selenoproteins in resolution of inflammation -- 43 Glutathione peroxidase 4 and ferroptosis -- 44 Mutations in humans that adversely affect the selenoprotein synthesis pathway -- 45 Alteration of selenoprotein expression during stress and in aging -- Part V. Biological models for elucidating the role of selenium and selenoproteins in biology and medicine -- 46 Selenocysteine tRNA[Ser]Sec mouse models for elucidating roles of selenoproteins in health and development -- 47 Mouse models that target individual selenoproteins -- 48 The naked mole rat and selenium -- 49 Glutathione peroxidase 1: Models for diabetes and obesity -- 50 Selenium in livestock and other domestic animals. |
| Record Nr. | UNINA-9910253898803321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Selenium : its molecular biology and role in human health / / edited by Dolph L. Hatfield, Marla J. Berry, Vadim N. Gladyshev
| Selenium : its molecular biology and role in human health / / edited by Dolph L. Hatfield, Marla J. Berry, Vadim N. Gladyshev |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | New York, NY, : Springer, c2006 |
| Descrizione fisica | 1 online resource (nnn pages) : illustrations ; ; digital file (PDF) |
| Disciplina | 572.555 |
| Altri autori (Persone) |
HatfieldDolph L
BerryMarla J GladyshevVadim N |
| Collana | Public health statement |
| Soggetto topico |
Selenium
Molecular biology Selenium - Physiological effect |
| ISBN |
1-281-75648-2
9786611756482 0-387-33827-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910703358903321 |
| New York, NY, : Springer, c2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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