Info
Molecular Biology of Selenium in Health and Disease
| Molecular Biology of Selenium in Health and Disease |
| Autore | Tsuji Petra A |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (384 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
14-3-3
Agrp neuron Akt angiogenesis antioxidant antioxidative defense autoantibody autoimmune thyroid disease autoimmunity bacteria barrier integrity cadmium cytotoxicity cancer cancer therapy cardiovascular cell death cell growth cisplatin colon cancer coxsackie virus diabetes mellitus diet-induced obesity differentiation early embryogenesis embryonic lethality endothelial cell genetic variance glutathione peroxidase Graves' disease Hashimoto thyroiditis Hashimoto's thyroiditis HBV HCV health heart HIV HIV-1 human disease hypothalamus ICP-MS infection inflammation influenza isopentenylation Jurkat Keshan's Disease leptin resistance lipid mediators long-COVID lymphocyte macrophage mouse models n/a NF-κB nonradioactive isotopes nonsense-mediated decay nonsynonymous mutation NRF2 primary T cells prostate reactive oxygen species recoding redox signaling rheumatoid arthritis ribosome rescue SEC-ICP MS Sec-tRNA[Ser]Sec SECIS SECIS-binding protein SECISBP2 selenite selenium selenium delivery system selenium homeostasis selenocysteine selenocysteine (Sec) Selenof SELENOO selenophosphate synthetase selenoprotein selenoprotein deficiency selenoprotein hierarchy selenoprotein P selenoprotein W selenoproteins selenoproteome SELENOS seleocysteine SEPHS1 SEPSECS sepsis sex differences SupT1 thioredoxin thioredoxin reductase trace element translation regulation translation termination translational control Trit1 tRNA[Ser]Sec Trsp tumor suppressor viral viral infection virus ZIP8 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566482103321 |
Tsuji Petra A
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Selenium : Its Molecular Biology and Role in Human Health / / edited by Dolph L. Hatfield, Ulrich Schweizer, Petra A. Tsuji, Vadim N. Gladyshev
| Selenium : Its Molecular Biology and Role in Human Health / / edited by Dolph L. Hatfield, Ulrich Schweizer, Petra A. Tsuji, Vadim N. Gladyshev |
| Edizione | [4th ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (XXXI, 628 p. 88 illus., 59 illus. in color.) |
| Disciplina | 616.079 |
| Soggetto topico |
Immunology
Nutrition |
| ISBN | 3-319-41283-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part I. The machinery of selenoprotein biosynthesis -- 1 Selenocysteine tRNA[Ser]Sec: From nonsense suppressor tRNA to the quintessential constituent in selenoprotein biosynthesis -- 2 Eukaryotic mechanisms of selenocysteine translation and its reconstitution in vitro -- 3 Probing selenoprotein translation by ribosome profiling -- 4 Pathways in de novo biosynthesis of selenocysteine and cysteine in eukaryotes -- 5 Prokaryotic selenoprotein biosynthesis and function -- 6 The role of selenium in human evolution -- 7 The chemistry of selenocysteine in proteins -- 8 Evolution of selenophosphate synthetase -- 9 Structure and mechanism of selenocysteine synthases -- 10 Mechanism, structure, and biological role of selenocysteine lyase -- Part II. Selenoproteins, their occurrence and function -- 11 Eukaryotic selenoproteomes -- 12 Prokaryotic selenoproteins and selenoproteomes -- 13 Functional genomics of selenoproteins and Se-responsive pathways -- 14 Selenium regulation of the selenoprotein and non-selenoprotein transcriptomes in a variety of species -- 15 77Se NMR spectroscopy of selenoproteins -- 16 Thioredoxin reductase 1 as an anticancer drug target -- 17 Basics and news on glutathione peroxidases -- 18 Glutathione Peroxidase 4 -- 19 The 15 kDa Selenoprotein: Insights into its regulation and function -- 20 Selenoprotein K and protein palmitoylation in regulating immune cell functions -- 21 Selenoprotein M: Structure, expression and functional relevance -- 22 Selenoprotein P and selenium distribution in mammals -- 23 Selenoprotein T: From discovery to functional studies using conditional knockout mice -- 24 Biochemistry and function of methionine sulfoxide reductase -- Part III. Dietary selenium and its impact on human health -- 25 Selenium: Dietary sources, human nutritional requirements and intake across populations -- 26 Human clinical trials involving selenium -- 27 Status of dietary selenium in cancer prevention -- 28 Selenium in HIV/AIDS -- 29 Genetic variations in the genes for selenoproteins implicate the encoded proteins in cancer etiology -- 30 Is adequate selenium important for healthy human pregnancy? -- 31 The epidemiology of selenium and human health -- 32 Sex-specific differences in biological effects and metabolism of selenium -- 33 Selenium and endocrine tissues -- 34 Selenium antagonism with mercury and arsenic: from chemistry to population health and demography -- 35 Biological selenium species and selenium speciation in biological samples -- 36 Selenoproteins in nervous system development, function and degeneration -- 37 Interplay of selenoproteins and different antioxidant systems in various cancers -- 38 Glutathione peroxidase 2, a selenoprotein exhibiting a dual personality in preventing and promoting cancer -- 39 Selenoproteins in cardiovascular redox pathology -- 40 What do we know about selenium contributions to muscle physiology? -- 41 Tissue-specific regulation of thyroid status by selenodeiodinases -- 42 The role of selenoproteins in resolution of inflammation -- 43 Glutathione peroxidase 4 and ferroptosis -- 44 Mutations in humans that adversely affect the selenoprotein synthesis pathway -- 45 Alteration of selenoprotein expression during stress and in aging -- Part V. Biological models for elucidating the role of selenium and selenoproteins in biology and medicine -- 46 Selenocysteine tRNA[Ser]Sec mouse models for elucidating roles of selenoproteins in health and development -- 47 Mouse models that target individual selenoproteins -- 48 The naked mole rat and selenium -- 49 Glutathione peroxidase 1: Models for diabetes and obesity -- 50 Selenium in livestock and other domestic animals. |
| Record Nr. | UNINA-9910253898803321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Selenium : Its Molecular Biology and Role in Human Health / / edited by Dolph L. Hatfield, Marla J. Berry, Vadim N. Gladyshev
| Selenium : Its Molecular Biology and Role in Human Health / / edited by Dolph L. Hatfield, Marla J. Berry, Vadim N. Gladyshev |
| Edizione | [2nd ed. 2006.] |
| Pubbl/distr/stampa | New York, NY : , : Springer US : , : Imprint : Springer, , 2006 |
| Descrizione fisica | 1 online resource (nnn pages) : illustrations ; ; digital file (PDF) |
| Disciplina | 572.555 |
| Altri autori (Persone) |
HatfieldDolph L
BerryMarla J GladyshevVadim N |
| Collana | Public health statement |
| Soggetto topico |
Cancer
Biochemistry Clinical biochemistry Immunology Oncology Nutrition Cancer Biology Medical Biochemistry |
| ISBN |
1-281-75648-2
9786611756482 0-387-33827-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Selenium: A historical perspective -- Selenium: A historical perspective -- Biosynthesis of selenocysteine and its incorporation into protein -- Selenium metabolism in prokaryotes -- Mammalian and other eukaryotic selenocysteine tRNAs -- Evolution of selenocysteine decoding and the key role of selenophosphate synthetase in the pathway of selenium utilization -- SECIS RNAs and K-turn binding proteins. A survey of evolutionary conserved RNA and protein motifs -- SECIS binding proteins and eukaryotic selenoprotein synthesis -- The importance of subcellular localization of SBP2 and EFsec for selenoprotein synthesis -- Selenocysteine biosynthesis and incorporation may require supramolecular complexes -- Selenium-containing proteins -- Selenoproteins and selenoproteomes -- Deletion of selenoprotein P gene in the mouse -- Selenium and methionine sulfoxide reduction -- Selenoprotein W in development and oxidative stress -- The 15-kDa selenoprotein (Sep15): functional analysis and role in cancer -- Regulation of glutathione peroxidase-1 expression -- Selenoproteins of the glutathione system -- New roles of glutathione peroxidase-1 in oxidative stress and diabetes -- Selenoproteins of the thioredoxin system -- Mitochondrial and cytosolic thioredoxin reductase knockout mice -- Selenium, deiodinases and endocrine function -- Biotechnology of selenocysteine -- Selenium and human health -- Selenium, selenoproteins and brain function -- Selenium as a cancer preventive agent -- Peering down the kaleidoscope of thiol proteomics and unfolded protein response in studying the anticancer action of selenium -- Genetic variation among selenoprotein genes and cancer -- Selenium and viral infections -- Role of selenium in HIV/AIDS -- Effects of selenium on immunity and aging -- Selenium and male reproduction -- Mouse models for assessing the role of selenoproteins in health and development -- Drosophila as a tool for studying selenium metabolism and role of selenoproteins -- Selenoproteins in parasites -- Incorporating ‘omics’ approaches to elucidate the role of selenium and selenoproteins in cancer prevention -- Selenium-induced apoptosis -- Selenoprotein mimics -- Update of human dietary standards for selenium. |
| Record Nr. | UNINA-9910703358903321 |
| New York, NY : , : Springer US : , : Imprint : Springer, , 2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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