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Cognitive Enhancement in Psychiatric Disorders
Cognitive Enhancement in Psychiatric Disorders
Autore Sumiyoshi Tomiki
Pubbl/distr/stampa Frontiers Media SA, 2019
Descrizione fisica 1 electronic resource (261 p.)
Soggetto topico Medicine
Psychiatry
Soggetto non controllato Cognition
Functional outcomes
Therapeutics
Assessment
Biomarkers
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910557496603321
Sumiyoshi Tomiki  
Frontiers Media SA, 2019
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Glutamate-Related Biomarkers for Neuropsychiatric Disorders
Glutamate-Related Biomarkers for Neuropsychiatric Disorders
Autore Lane Hsien-Yuan
Pubbl/distr/stampa Frontiers Media SA, 2020
Descrizione fisica 1 electronic resource (115 p.)
Soggetto topico Medicine
Psychiatry
Soggetto non controllato glutamate
NMDA
schizophrenia
depression
Alzheimer's disease
autoimmune encephalitis
autism
addiction
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910557572303321
Lane Hsien-Yuan  
Frontiers Media SA, 2020
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Ketamine [[electronic resource] ] : From Abused Drug to Rapid-Acting Antidepressant / / edited by Kenji Hashimoto, Soichiro Ide, Kazutaka Ikeda
Ketamine [[electronic resource] ] : From Abused Drug to Rapid-Acting Antidepressant / / edited by Kenji Hashimoto, Soichiro Ide, Kazutaka Ikeda
Edizione [1st ed. 2020.]
Pubbl/distr/stampa Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020
Descrizione fisica 1 online resource (V, 189 p. 27 illus., 13 illus. in color.)
Disciplina 615.781
Soggetto topico Neurosciences
Pharmacology
Laboratory medicine
Neurobiology
Neuropsychology
Neurology 
Pharmacology/Toxicology
Laboratory Medicine
Neurology
ISBN 981-15-2902-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1.Determination of ketamine in the river of China -- 2.Ketamine abuse in Taiwan -- 3.Ketamine problem in Hong Kong -- 4. Hair analysis of ketamine -- 5. Brain imaging of ketamine abusers -- 6.Management of complications of ketamine abuse -- 7.Action site of ketamine in the NMDA receptor channel -- 8.Synaptic modulation in the effect of ketamine -- 9.Rodents whole-brain imaging in the effects of ketamine -- 10. Behavioral pharmacology of ketamine: An overview of preclinical studies -- 11.Antidepressant potential of ketamine enantiomers -- 12.Effects of ketamine on pain-related depression -- 13.Role of gut microbiota in the antidepressant actions of ketamine and its enantiomers -- 14. The role of NMDA receptor GluN2D subunit in the effects of ketamine and enantiomers -- 15.Roles of the lateral habenula in the actions of ketamine -- 16.Comparison of antidepressant action of ketamine and group II mGlu receptor antagonists -- 17.Antidepressant effects of ketamine in Taiwanese patients with treatment-resistant depression.
Record Nr. UNINA-9910409684703321
Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020
Materiale a stampa
Lo trovi qui: Univ. Federico II
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New rapid-acting Antidepressants / / edited by Kenji Hashimoto and Mario Manto
New rapid-acting Antidepressants / / edited by Kenji Hashimoto and Mario Manto
Pubbl/distr/stampa Cham, Switzerland : , : Springer, , [2021]
Descrizione fisica 1 online resource (152 pages)
Disciplina 616.8527061
Collana Contemporary Clinical Neuroscience
Soggetto topico Neurosciences
Antidepressants
Antidepressius
Soggetto genere / forma Llibres electrònics
ISBN 3-030-79790-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Intro -- Preface -- Contents -- (R)-Ketamine: A New Rapid-Acting Antidepressant -- Rapid-Acting Antidepressant Ketamine -- What Is (R)-Ketamine? -- (R)-Ketamine's Antidepressant Effects -- Gender Differences -- (R)-Ketamine and its Final Metabolite, (2R,6R)-Hydroxynorketamine -- Side Effects -- Potential Mechanisms of Ketamine's Antidepressant Actions -- 5-Hydroxytryptamine -- α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptor Activation -- Dopamine -- Opioid System -- γ-Aminobutyric Acid -- Inflammatory Bone Markers -- ERK -- Gut Microbiota -- Conclusion -- References -- (2R,6R)-Hydroxynorketamine, A Metabolite of Ketamine: The Antidepressant Actions and the Mechanisms -- Introduction -- Antidepressant-like Actions of (2R,6R)-Hydroxynorketamine -- Brain Regions for the Antidepressant-like Actions of (2R,6R)-Hydroxynorketamine -- Potential Mechanisms of Antidepressant-like Actions of (2R,6R)-Hydroxynorketamine -- Conclusion -- References -- Predictable Biomarkers for Rapid-Acting Antidepressant Response to Ketamine -- Introduction -- Brain-Derived Neurotrophic Factor -- Shank3 -- Dissociation -- Inflammatory Markers, D-Serine, and Vitamin B12 -- Body Mass Index -- Kynurenine Pathway -- Gamma Power -- Neuroimaging -- Structural and Functional Connectivity -- Sleep -- Cognition -- Conclusion -- References -- Nitrous Oxide: An Old Compound with Emerging Psychotropic Properties -- Brief Medical History of Nitrous Oxide -- Current Medical Applications of Nitrous Oxide -- Nitrous Oxide as an Antidepressant -- Putative Mechanisms of Nitrous Oxide as an Antidepressant -- Administration of Nitrous Oxide -- Dosing of Nitrous Oxide in Depression -- Administration of Nitrous Oxide in Depression -- Nitrous Oxide Abuse Potential -- Nitrous Oxide Compared to Ketamine -- Future Directions -- References.
Novel AMPA Receptor Potentiators TAK-137 and TAK-653 as Potential Rapid-Acting Antidepressants -- Introduction -- Establishment of a Novel Drug Screening Strategy for AMPA-R Potentiators -- Characterization of AMPA-R Potentiators Containing a Dihydropyridothiadiazine 2,2-Dioxide Skeleton with a Different Agonistic Effect -- Discovery and Characterization of TAK-137 -- In Vitro Characterization of TAK-137 Using LY451646 as a Control -- Potent Procognitive Effects and Lower Bell-Shaped Response and Seizure Risks with TAK-137 -- Antidepressant-Like Activity of TAK-137 in Rodents -- Discovery and Characterization of TAK-653 -- Antidepressant-like Activity of TAK-653 in Rodents -- Pharmacokinetic Properties of TAK-653 After Single and Multiple Rising Doses in Healthy Volunteers -- Conclusions -- References -- AMPA Receptor Potentiators as Potential Rapid-Acting Antidepressants -- Introduction -- AMPA Receptors -- AMPA Receptors in Depression -- Effects of Antidepressant Treatments on AMPA Receptors -- History of AMPA Receptor Potentiators -- AMPAR Potentiators as Antidepressants -- Intracellular Signaling of AMPA Receptor Potentiators -- Conclusion -- References -- mGlu2/3 Receptor Antagonists as Rapid-Acting Antidepressants -- Introduction -- mGlu2/3 Receptors: Molecular Properties, Functions, and Roles in Psychiatric Disorders -- Antidepressant Profiles of mGlu2/3 Receptor Antagonists in Rodent Models -- Antidepressant Effects of Stimulation of mGlu2/3 and/or mGlu2 Receptors -- Mechanisms Underlying the Antidepressant Effects of mGlu2/3 Receptor Antagonists -- Synaptic Mechanisms of the Antidepressant Effects of mGlu2/3 Receptor Antagonists -- Role of Monoaminergic Systems in the Antidepressant Actions of mGlu2/3 Receptor Antagonists -- Conclusions -- References.
Antidepressant Effects of the Muscarinic Receptor Antagonist Scopolamine: Clinical and Preclinical Review -- Muscarinic Cholinergic Antagonists in the Treatment of Mood Disorders -- Rapid Antidepressant Response to Scopolamine -- Adverse Effects -- Onset and Duration of Scopolamine's Clinical Antidepressant Effects -- Limitations of the Extant Data -- Other Clinical Studies Using Repeated Scopolamine Administrations in Depression -- Advancing Scopolamine Through Reverse Translation -- Scopolamine in Preclinical Models -- Identifying a More Selective Antimuscarinic Antidepressant -- Summary -- Financial Disclosures -- References -- Index.
Record Nr. UNINA-9910506387603321
Cham, Switzerland : , : Springer, , [2021]
Materiale a stampa
Lo trovi qui: Univ. Federico II
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The NMDA Receptors [[electronic resource] /] / edited by Kenji Hashimoto
The NMDA Receptors [[electronic resource] /] / edited by Kenji Hashimoto
Edizione [1st ed. 2017.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Humana, , 2017
Descrizione fisica 1 online resource (X, 148 p. 22 illus., 14 illus. in color.)
Disciplina 612.8
Collana The Receptors
Soggetto topico Neurosciences
ISBN 9783319497952
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Chapter 1. Overview of the NMDA receptor by Hisashi Mori -- 2. Synaptic and extra-synaptic NMDA receptors in the CNS by Thomas Papouin and Stéphane H.R. Oliet -- 3. Functional Distribution and Regulation of the NMDAR in the Kidney, Heart and Parathyroid Gland by Milica Bozic and José M. Valdivielso -- 4. Rapid Antidepressant Activity of Ketamine beyond NMDA Receptor by Kenji Hashimoto -- 5. D-aspartate, an atypical amino acid with NMDA receptor agonist features: involvement in schizophrenia by F. Errico and A. Usiello -- 6. NMDA Receptors and Signaling in Chronic Neuropathic Pain by Geoffroy Laumet, Shao-Rui Chen, and Hui-Lin Pan -- 7. Role of NMDA receptors in pancreatic islets by Okka Scholz, Alena Welters and Eckhard Lammert -- 8. NMDA Receptor in Bone by Yukio Yoneda.
Record Nr. UNINA-9910163986703321
Cham : , : Springer International Publishing : , : Imprint : Humana, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
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