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Advance in the Treatment of Pediatric Leukemia
| Advance in the Treatment of Pediatric Leukemia |
| Autore | Handgretinger Rupert |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (300 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
5-azacitidine
ABCC4 acute lymphoblastic leukemia acute myeloid leukemia acute pancreatitis ADC advances ALL allogeneic stem cell transplantation alternative donors AML antibody antibody-drug conjugate B-ALL BCL11B BCP-ALL bispecific T-cell engager (BiTE) CD19 CFTR childhood acute lymphoblastic leukemia children chronic myeloid leukemia CML conditioning regimen COVID-19 diagnosis DUX4 evolution of CAR T cells Fc-engineering FDA-approved CAR products future directions of CAR T cell therapy genome hematopoietic stem cell transplantation IKZF1 immunizations immunotherapy juvenile myelomonocytic leukemia L-asparaginase leukemia limitations and complications of CAR T cell therapy low-risk ALL lymphoblastic leukemia minimal residual disease myelodysplastic/myeloproliferative disorders n/a NOTCH1 NUTM1 other extramedullary relapse PAX5 pediatric pediatric leukemia Ph-like polymorphism prognosis RAS signaling risk-stratified treatment SNV T-ALL targeted therapy TcR versus CAR TRAIL transcriptome treatment treatment related toxicity tyrosine kinase inhibitor xenograft ZNF384 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576878903321 |
Handgretinger Rupert
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Haploidentical Transplantation : Concepts & Clinical Application / / edited by Stefan O. Ciurea, Rupert Handgretinger
| Haploidentical Transplantation : Concepts & Clinical Application / / edited by Stefan O. Ciurea, Rupert Handgretinger |
| Edizione | [1st ed. 2018.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
| Descrizione fisica | 1 online resource (330 pages) |
| Disciplina | 616.15 |
| Collana | Advances and Controversies in Hematopoietic Transplantation and Cell Therapy |
| Soggetto topico |
Hematology
Oncology |
| ISBN | 3-319-54310-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Historical perspective and current trends in haploidentical transplantion -- Part 1: Graft manipulation and methods to control T-cell alloreactivity. -Positive CD34+ cell selection -- Selective allo-depletion: αβ and CD19+ cell T cell depletion -- T cell addback in T- cell depleted haploidentical transplant -- Hematopoietic myeloid growth factor primed bone marrow and peripheral blood hematopoietic progenitor cells -- Photodepletion of allo-reactive T cells -- Post-transplant cyclophosphamide in haploidentical transplant -- Part 2: Ideal graft & donor -- Graft source: Marrow versus peripheral blood with PTCy- Does it matter? -- Anti-HLA antibodies: Assessment and mitigating strategies -- Selection of haploidentical donors: What is the art? -- Myeloablative versus non-myeloablative conditioning regimen- Does it matter and how best to select? -- Part 3: Disease-specific pediatric population -- Nonmalignant diseases in children.- en.-="" part="" 4:="" disease-specific="" adult="" population.-="" non-malignant="" adults.-="" acute="" myelogenous="" leukemia="" lymphomas-="" parameswaran="" hari.-="" chronic="" leukemias="" and="" myeloproliferative="" neoplasms.-="" immunologic="" reconstitution="" after="" haploidentical="" transplantation.-="" prevention="" treatment="" of="" relapse="" transplant.-="" unique="" complications="" limitations="" future="" prospects="" transplantation. |
| Record Nr. | UNINA-9910300266603321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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