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Cancer biomarkers [[electronic resource] ] : analytical techniques for discovery / / Mahmoud H. Hamdan
Cancer biomarkers [[electronic resource] ] : analytical techniques for discovery / / Mahmoud H. Hamdan
Autore Hamdan Mahmoud <1947->
Pubbl/distr/stampa Hoboken, N.J., : Wiley-Interscience, c2007
Descrizione fisica 1 online resource (405 p.)
Disciplina 616.994075
Collana Wiley-Interscience series on mass spectrometry
Soggetto topico Tumor markers
Soggetto genere / forma Electronic books.
ISBN 1-280-82219-8
9786610822195
0-470-11312-X
0-470-11311-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Overview -- Proteomic platforms for biomarkers discovery -- Some existing cancer biomarkers -- Potential cancer biomarkers -- Protein networks and protein phosphorylation in cancer -- Ethical issues and initiatives relevant to cancer biomarkers.
Record Nr. UNINA-9910143419303321
Hamdan Mahmoud <1947->  
Hoboken, N.J., : Wiley-Interscience, c2007
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Cancer biomarkers [[electronic resource] ] : analytical techniques for discovery / / Mahmoud H. Hamdan
Cancer biomarkers [[electronic resource] ] : analytical techniques for discovery / / Mahmoud H. Hamdan
Autore Hamdan Mahmoud <1947->
Pubbl/distr/stampa Hoboken, N.J., : Wiley-Interscience, c2007
Descrizione fisica 1 online resource (405 p.)
Disciplina 616.994075
Collana Wiley-Interscience series on mass spectrometry
Soggetto topico Tumor markers
ISBN 1-280-82219-8
9786610822195
0-470-11312-X
0-470-11311-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Overview -- Proteomic platforms for biomarkers discovery -- Some existing cancer biomarkers -- Potential cancer biomarkers -- Protein networks and protein phosphorylation in cancer -- Ethical issues and initiatives relevant to cancer biomarkers.
Record Nr. UNINA-9910829908303321
Hamdan Mahmoud <1947->  
Hoboken, N.J., : Wiley-Interscience, c2007
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Cancer biomarkers [[electronic resource] ] : analytical techniques for discovery / / Mahmoud H. Hamdan
Cancer biomarkers [[electronic resource] ] : analytical techniques for discovery / / Mahmoud H. Hamdan
Autore Hamdan Mahmoud <1947->
Pubbl/distr/stampa Hoboken, N.J., : Wiley-Interscience, c2007
Descrizione fisica 1 online resource (405 p.)
Disciplina 616.994075
Collana Wiley-Interscience series on mass spectrometry
Soggetto topico Tumor markers
ISBN 1-280-82219-8
9786610822195
0-470-11312-X
0-470-11311-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Overview -- Proteomic platforms for biomarkers discovery -- Some existing cancer biomarkers -- Potential cancer biomarkers -- Protein networks and protein phosphorylation in cancer -- Ethical issues and initiatives relevant to cancer biomarkers.
Record Nr. UNINA-9910841503903321
Hamdan Mahmoud <1947->  
Hoboken, N.J., : Wiley-Interscience, c2007
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Proteomics today [[electronic resource] ] : protein assessment and biomarkers using mass spectrometry, 2D electrophoresis, and microarray technology / / Mahmoud Hamdan, Pier Giorgio Righetti
Proteomics today [[electronic resource] ] : protein assessment and biomarkers using mass spectrometry, 2D electrophoresis, and microarray technology / / Mahmoud Hamdan, Pier Giorgio Righetti
Autore Hamdan Mahmoud <1947->
Pubbl/distr/stampa Hoboken, N.J., : John Wiley & Sons, 2005
Descrizione fisica 1 online resource (446 p.)
Disciplina 572.6
572.636
Altri autori (Persone) RighettiP. G
Collana Wiley-Interscience series in mass spectrometry
Soggetto topico Proteins - Spectra
Mass spectrometry
Proteomics
Soggetto genere / forma Electronic books.
ISBN 1-280-27548-0
9786610275489
0-470-24684-7
0-471-70910-7
0-471-70915-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto PROTEOMICS TODAY; CONTENTS; PREFACE TO PART I; ACKNOWLEDGMENT; I INTRODUCTION TO PART I; 1 INSTRUMENTATION AND DEVELOPMENTS; 1.1 Introduction; 1.2 Ionization Techniques for Macromolecules; 1.2.1 (252)Cf Plasma Desorption Ionization; 1.2.2 Fast Atom/Ion Bombardment; 1.2.3 Type of Fragment Ions and Nomenclature; 1.3 Examples on Analytical Solutions Based on FAB-MS; 1.3.1 Detection of Abnormalities in Hemoglobin; 1.3.2 Glycoprotein Structure Determination; 1.3.3 Early Scanning Functions on Sector Machines; 1.4 Electrospray Ionization; 1.5 Matrix-Assisted Laser Desorption Ionization
1.5.1 MALDI at High Pressure1.5.2 Desorption Ionization on Silicon (DIOS); 1.5.3 Delayed Extraction; 1.6 Ion Detection; 1.6.1 Microchannel Plates (MCPs); 1.6.2 Cryogenic Detectors; 1.6.2.1 Superconducting Tunnel Junction; 1.6.2.2 Thermal Detectors; 1.7 Types of Analyzers; 1.7.1 Quadrupole Mass Filter; 1.7.2 Three-Dimensional Quadrupole Ion Trap; 1.7.3 Linear Ion Trap; 1.7.4 Time of Flight; 1.7.5 Fourier Transform Ion Cyclotron Resonance; 1.8 Hybrid Analyzers; 1.8.1 Quadrupole Time of Flight; 1.8.2 Ion Mobility-TOF; 1.8.3 Linear Ion Trap-FT-ICR; 1.8.4 Ion Trap-TOF; 1.9 Tandem Mass Spectrometry
1.9.1 Postsource Decay1.9.2 MS-MS Measurements; 1.9.3 Collisional Activation; 1.10 Current MS Instrumentation in Proteome Analyses; 1.10.1 MALDI-TOF; 1.10.2 MALDI-TOF-TOF; 1.10.3 FT-ICR-MS; 1.10.4 ION Mobility-MS; 1.11 Current MS-Based Proteomics; 1.11.1 Delivering Peptides to Ion Source; 1.11.2 Peptide Sequencing and Database Searching; 1.11.3 Peptide Mass Fingerprinting; 1.11.4 Searching with MS-MS Data; 1.11.5 Databases for MS Data Search; 1.12 Recent Achievements and Future Challenges; 1.12.1 Current Applications; 1.12.2 Signal Transduction Pathways; 1.13 Concluding Remarks; References
2 PROTEOMICS IN CANCER RESEARCH2.1 Introduction; 2.1.1 Two-Dimensional Gel Electrophoresis; 2.1.2 Surface-Enhanced Laser Desorption Ionization; 2.1.3 Protein Microarrays; 2.1.4 Getting More Than Just Simple Change in Protein Expression; 2.1.5 Laser Capture Microdissection; 2.2 Pancreatic Ductal Adenocarcinoma; 2.2.1 Analyses Based on Chip Technology; 2.2.2 SELDI Analysis of Pancreatic Ductal Adenocarcinoma; 2.2.3 Protein Profiling Following Treatment with DNA Methylation/Histone Deacetylation Inhibitors; 2.2.4 Proteomic Profiling of PDAC Following Treatment with Trichostatin A
2.2.5 Proteomic Profiling of PDAC Following Treatment with 5 ́-aza-2 ́-deoxycytidine2.3 Proteomic Analysis of Human Breast Carcinoma; 2.3.1 Two-DE Analysis in Breast Cancer; 2.3.2 Proteomic Profiling of Breast Cancer Cell Membranes; 2.3.3 Proteomic Analysis on Selected Tissue Samples; 2.4 Proteomic Profiling of Chemoresistant Cancer Cells; 2.4.1 Protein Alterations in Pancreas Carcinoma Cells Exposed to Anticancer Drug; 2.4.2 Proteomic Profiling of Cervix Squamous Cell Carcinoma Treated with Cisplatin; 2.5 Signal Pathway Profiling of Prostate Cancer
2.6 Emerging Role of Functional and Activity-Based Proteomics in Disease Understanding
Record Nr. UNINA-9910144639903321
Hamdan Mahmoud <1947->  
Hoboken, N.J., : John Wiley & Sons, 2005
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Proteomics today [[electronic resource] ] : protein assessment and biomarkers using mass spectrometry, 2D electrophoresis, and microarray technology / / Mahmoud Hamdan, Pier Giorgio Righetti
Proteomics today [[electronic resource] ] : protein assessment and biomarkers using mass spectrometry, 2D electrophoresis, and microarray technology / / Mahmoud Hamdan, Pier Giorgio Righetti
Autore Hamdan Mahmoud <1947->
Pubbl/distr/stampa Hoboken, N.J., : John Wiley & Sons, 2005
Descrizione fisica 1 online resource (446 p.)
Disciplina 572.6
572.636
Altri autori (Persone) RighettiP. G
Collana Wiley-Interscience series in mass spectrometry
Soggetto topico Proteins - Spectra
Mass spectrometry
Proteomics
ISBN 1-280-27548-0
9786610275489
0-470-24684-7
0-471-70910-7
0-471-70915-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto PROTEOMICS TODAY; CONTENTS; PREFACE TO PART I; ACKNOWLEDGMENT; I INTRODUCTION TO PART I; 1 INSTRUMENTATION AND DEVELOPMENTS; 1.1 Introduction; 1.2 Ionization Techniques for Macromolecules; 1.2.1 (252)Cf Plasma Desorption Ionization; 1.2.2 Fast Atom/Ion Bombardment; 1.2.3 Type of Fragment Ions and Nomenclature; 1.3 Examples on Analytical Solutions Based on FAB-MS; 1.3.1 Detection of Abnormalities in Hemoglobin; 1.3.2 Glycoprotein Structure Determination; 1.3.3 Early Scanning Functions on Sector Machines; 1.4 Electrospray Ionization; 1.5 Matrix-Assisted Laser Desorption Ionization
1.5.1 MALDI at High Pressure1.5.2 Desorption Ionization on Silicon (DIOS); 1.5.3 Delayed Extraction; 1.6 Ion Detection; 1.6.1 Microchannel Plates (MCPs); 1.6.2 Cryogenic Detectors; 1.6.2.1 Superconducting Tunnel Junction; 1.6.2.2 Thermal Detectors; 1.7 Types of Analyzers; 1.7.1 Quadrupole Mass Filter; 1.7.2 Three-Dimensional Quadrupole Ion Trap; 1.7.3 Linear Ion Trap; 1.7.4 Time of Flight; 1.7.5 Fourier Transform Ion Cyclotron Resonance; 1.8 Hybrid Analyzers; 1.8.1 Quadrupole Time of Flight; 1.8.2 Ion Mobility-TOF; 1.8.3 Linear Ion Trap-FT-ICR; 1.8.4 Ion Trap-TOF; 1.9 Tandem Mass Spectrometry
1.9.1 Postsource Decay1.9.2 MS-MS Measurements; 1.9.3 Collisional Activation; 1.10 Current MS Instrumentation in Proteome Analyses; 1.10.1 MALDI-TOF; 1.10.2 MALDI-TOF-TOF; 1.10.3 FT-ICR-MS; 1.10.4 ION Mobility-MS; 1.11 Current MS-Based Proteomics; 1.11.1 Delivering Peptides to Ion Source; 1.11.2 Peptide Sequencing and Database Searching; 1.11.3 Peptide Mass Fingerprinting; 1.11.4 Searching with MS-MS Data; 1.11.5 Databases for MS Data Search; 1.12 Recent Achievements and Future Challenges; 1.12.1 Current Applications; 1.12.2 Signal Transduction Pathways; 1.13 Concluding Remarks; References
2 PROTEOMICS IN CANCER RESEARCH2.1 Introduction; 2.1.1 Two-Dimensional Gel Electrophoresis; 2.1.2 Surface-Enhanced Laser Desorption Ionization; 2.1.3 Protein Microarrays; 2.1.4 Getting More Than Just Simple Change in Protein Expression; 2.1.5 Laser Capture Microdissection; 2.2 Pancreatic Ductal Adenocarcinoma; 2.2.1 Analyses Based on Chip Technology; 2.2.2 SELDI Analysis of Pancreatic Ductal Adenocarcinoma; 2.2.3 Protein Profiling Following Treatment with DNA Methylation/Histone Deacetylation Inhibitors; 2.2.4 Proteomic Profiling of PDAC Following Treatment with Trichostatin A
2.2.5 Proteomic Profiling of PDAC Following Treatment with 5 ́-aza-2 ́-deoxycytidine2.3 Proteomic Analysis of Human Breast Carcinoma; 2.3.1 Two-DE Analysis in Breast Cancer; 2.3.2 Proteomic Profiling of Breast Cancer Cell Membranes; 2.3.3 Proteomic Analysis on Selected Tissue Samples; 2.4 Proteomic Profiling of Chemoresistant Cancer Cells; 2.4.1 Protein Alterations in Pancreas Carcinoma Cells Exposed to Anticancer Drug; 2.4.2 Proteomic Profiling of Cervix Squamous Cell Carcinoma Treated with Cisplatin; 2.5 Signal Pathway Profiling of Prostate Cancer
2.6 Emerging Role of Functional and Activity-Based Proteomics in Disease Understanding
Record Nr. UNINA-9910831066403321
Hamdan Mahmoud <1947->  
Hoboken, N.J., : John Wiley & Sons, 2005
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Proteomics today [[electronic resource] ] : protein assessment and biomarkers using mass spectrometry, 2D electrophoresis, and microarray technology / / Mahmoud Hamdan, Pier Giorgio Righetti
Proteomics today [[electronic resource] ] : protein assessment and biomarkers using mass spectrometry, 2D electrophoresis, and microarray technology / / Mahmoud Hamdan, Pier Giorgio Righetti
Autore Hamdan Mahmoud <1947->
Pubbl/distr/stampa Hoboken, N.J., : John Wiley & Sons, 2005
Descrizione fisica 1 online resource (446 p.)
Disciplina 572.6
572.636
Altri autori (Persone) RighettiP. G
Collana Wiley-Interscience series in mass spectrometry
Soggetto topico Proteins - Spectra
Mass spectrometry
Proteomics
ISBN 1-280-27548-0
9786610275489
0-470-24684-7
0-471-70910-7
0-471-70915-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto PROTEOMICS TODAY; CONTENTS; PREFACE TO PART I; ACKNOWLEDGMENT; I INTRODUCTION TO PART I; 1 INSTRUMENTATION AND DEVELOPMENTS; 1.1 Introduction; 1.2 Ionization Techniques for Macromolecules; 1.2.1 (252)Cf Plasma Desorption Ionization; 1.2.2 Fast Atom/Ion Bombardment; 1.2.3 Type of Fragment Ions and Nomenclature; 1.3 Examples on Analytical Solutions Based on FAB-MS; 1.3.1 Detection of Abnormalities in Hemoglobin; 1.3.2 Glycoprotein Structure Determination; 1.3.3 Early Scanning Functions on Sector Machines; 1.4 Electrospray Ionization; 1.5 Matrix-Assisted Laser Desorption Ionization
1.5.1 MALDI at High Pressure1.5.2 Desorption Ionization on Silicon (DIOS); 1.5.3 Delayed Extraction; 1.6 Ion Detection; 1.6.1 Microchannel Plates (MCPs); 1.6.2 Cryogenic Detectors; 1.6.2.1 Superconducting Tunnel Junction; 1.6.2.2 Thermal Detectors; 1.7 Types of Analyzers; 1.7.1 Quadrupole Mass Filter; 1.7.2 Three-Dimensional Quadrupole Ion Trap; 1.7.3 Linear Ion Trap; 1.7.4 Time of Flight; 1.7.5 Fourier Transform Ion Cyclotron Resonance; 1.8 Hybrid Analyzers; 1.8.1 Quadrupole Time of Flight; 1.8.2 Ion Mobility-TOF; 1.8.3 Linear Ion Trap-FT-ICR; 1.8.4 Ion Trap-TOF; 1.9 Tandem Mass Spectrometry
1.9.1 Postsource Decay1.9.2 MS-MS Measurements; 1.9.3 Collisional Activation; 1.10 Current MS Instrumentation in Proteome Analyses; 1.10.1 MALDI-TOF; 1.10.2 MALDI-TOF-TOF; 1.10.3 FT-ICR-MS; 1.10.4 ION Mobility-MS; 1.11 Current MS-Based Proteomics; 1.11.1 Delivering Peptides to Ion Source; 1.11.2 Peptide Sequencing and Database Searching; 1.11.3 Peptide Mass Fingerprinting; 1.11.4 Searching with MS-MS Data; 1.11.5 Databases for MS Data Search; 1.12 Recent Achievements and Future Challenges; 1.12.1 Current Applications; 1.12.2 Signal Transduction Pathways; 1.13 Concluding Remarks; References
2 PROTEOMICS IN CANCER RESEARCH2.1 Introduction; 2.1.1 Two-Dimensional Gel Electrophoresis; 2.1.2 Surface-Enhanced Laser Desorption Ionization; 2.1.3 Protein Microarrays; 2.1.4 Getting More Than Just Simple Change in Protein Expression; 2.1.5 Laser Capture Microdissection; 2.2 Pancreatic Ductal Adenocarcinoma; 2.2.1 Analyses Based on Chip Technology; 2.2.2 SELDI Analysis of Pancreatic Ductal Adenocarcinoma; 2.2.3 Protein Profiling Following Treatment with DNA Methylation/Histone Deacetylation Inhibitors; 2.2.4 Proteomic Profiling of PDAC Following Treatment with Trichostatin A
2.2.5 Proteomic Profiling of PDAC Following Treatment with 5 ́-aza-2 ́-deoxycytidine2.3 Proteomic Analysis of Human Breast Carcinoma; 2.3.1 Two-DE Analysis in Breast Cancer; 2.3.2 Proteomic Profiling of Breast Cancer Cell Membranes; 2.3.3 Proteomic Analysis on Selected Tissue Samples; 2.4 Proteomic Profiling of Chemoresistant Cancer Cells; 2.4.1 Protein Alterations in Pancreas Carcinoma Cells Exposed to Anticancer Drug; 2.4.2 Proteomic Profiling of Cervix Squamous Cell Carcinoma Treated with Cisplatin; 2.5 Signal Pathway Profiling of Prostate Cancer
2.6 Emerging Role of Functional and Activity-Based Proteomics in Disease Understanding
Record Nr. UNINA-9910841482603321
Hamdan Mahmoud <1947->  
Hoboken, N.J., : John Wiley & Sons, 2005
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui