Autore	Hallgrímsson Benedikt
Edizione	[1st ed.]
Pubbl/distr/stampa	Berkeley, : University of California Press, c2011
Descrizione fisica	1 online resource (469 p.)
Disciplina	576.5/3
Altri autori (Persone)	HallgrímssonBenedikt HallBrian Keith <1941->
Soggetto topico	Phenotype Epigenesis Genotype-environment interaction Genetic regulation Developmental genetics Evolutionary genetics
Soggetto non controllato	adaptation allele asymmetry biological systems biology bone morphology brain cardiac neural crest cell differentiation chromatin developmental biology disease dysmorphology epigenetics evolution evolutionary biology genetic assimilation genetic traits genetics genotype healthcare life sciences mandible medicine morphogenesis nonfiction organ formation phenotype science technology tooth development waddington
ISBN	1-283-33185-3 9786613331854 0-520-94882-3
Classificazione	WG 1940
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	Frontmatter -- Contents -- Contributors -- 1. Introduction -- 2. A Brief History of the Term and Concept Epigenetics -- 3. Heuristic Reductionism and the Relative significance of Epigenetic Inheritance in evolution -- 4. The Epigenetics of Genomic Imprinting: Core Epigenetic Processes are conserved in Mammals, Insects, and Plants -- 5. Methylation Mapping in Humans -- 6. Asexuality and Epigenetic Variation -- 7. Epigenesis, Preformation, and the Humpty Dumpty Problem -- 8. A Principle of Developmental Inertia -- 9. The Role of Epigenetics in Nervous System Development -- 10. Morphogenesis of Pigment Patterns: Experimental and Modeling Approaches -- 11. Epigenetic Interactions of the Cardiac Neural Crest -- 12. Epigenetics in Bone and cartilage Development -- 13. Muscle-Bone Interactions and the Development of skeletal Phenotype: Jaw muscles and the skull -- 14. Evolution of the Apical Ectoderm in the Developing Vertebrate Limb -- 15. Role of Skeletal Muscle in the Epigenetic Shaping of Organs, Tissues, and Cell Fate Choices -- 16. Epigenetic Integration, Complexity, and Evolvability of the Head: Rethinking the Functional Matrix Hypothesis -- 17. Epigenetic Interactions: The Developmental Route to Functional Integration -- 18. Epigenetic Contributions to Adaptive Radiation: Insights from Threespine Stickleback -- 19. Learning, Developmental Plasticity, and the Rate of Morphological Evolution -- 20. Epigenetics: Adaptation or Contingency? -- 21. The Epigenetics of Dysmorphology. Craniosynostosis as an Example -- 22. Epigenetics of Human Disease -- 23. Epigenetics: The Context of Development -- Index
Record Nr.	UNINA-9910791806903321

Pubbl/distr/stampa	Amsterdam ; ; Boston, : Elsevier Academic Press, c2005
Descrizione fisica	1 online resource (594 p.)
Disciplina	576.5/4
Altri autori (Persone)	HallgrímssonBenedikt HallBrian Keith <1941->
Soggetto topico	Variation (Biology)
Soggetto genere / forma	Electronic books.
ISBN	1-280-63060-4 9786610630608 0-08-045446-1
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	Variation; Variation; CONTENTS; Variation and Variability: Central Concepts in Biology; REFERENCES; Variation from Darwin to the Modern Synthesis; INTRODUCTION; I. VARIATION BEFORE DARWIN; II. DARWIN AND VARIATION; III. ALTERNATIVE THEORIES OF VARIATION AND EVOLUTION; IV. NEO-DARWINISM; V. THE EVOLUTIONARY SYNTHESIS; VI. CONCLUSIONS; REFERENCES; The Statistics of Variation; ABSTRACT; INTRODUCTION; I. ABSOLUTE VARIATION: UNIVARIATE CASE; II. ABSOLUTE VARIATION: MULTIVARIATE CASE; III. RELATIVE VARIATION: UNIVARIATE CASE; IV. RELATIVE VARIATION: MULTIVARIATE CASE; V. DIMENSIONALITY OF VARIATION VI. TIGHTNESSVII. MEASUREMENT ERROR AND SINGLE SPECIMENS; REFERENCES; Landmark Morphometrics and the Analysis of Variation; INTRODUCTION; I. COORDINATE DATA AND THE COORDINATE SYSTEM; II. THE GENERAL PERTURBATION MODEL FOR LANDMARK VARIATION; III. PROPER ELIMINATION OF NUISANCE PARAMETERS USING A COORDINATE SYSTEM INVARIANT METHOD OF ESTIMATION; IV. ADDING ASSUMPTIONS TO THE PERTURBATION MODEL; V. CONCLUSIONS; ACKNOWLEDGMENTS; REFERENCES; Variation in Ontogeny; INTRODUCTION; I. MEASURING VARIATION: A CASE STUDY; II. IMPLICATIONS FOR STUDIES OF VARIATION; III. CONCLUSIONS; ACKNOWLEDGMENTS REFERENCESConstraints on Variation from Genotype through Phenotype to Fitness; INTRODUCTION; I. RNA EVOLUTIONARY MODEL; II. EVOLVING CONSTRAINTS ON VARIATION IN RNA; III. MECHANISTIC CONSTRAINTS; IV. EPISTATIC CONSTRAINTS; V. VIABILITY CONSTRAINTS; VI. MODULARITY: A WAY OUT OF THE CONSTRAINTS; ACKNOWLEDGMENTS; REFERENCES; Developmental Origins of Variation; INTRODUCTION; I. DOES INTRINSIC DEVELOPMENTAL VARIATION EXIST?; II. INTRINSIC VARIATION IN DIFFERENT ENVIRONMENTS; III. POTENTIAL ORIGINS OF INTRINSIC DEVELOPMENTAL VARIATION; IV. AN EXAMPLE OF NOISE IN EUKARYOTIC TRANSCRIPTION V. NOISY BICOID GENE EXPRESSION IN FRUIT FLIESVI. NOISE IN ASYMMETRY PRODUCTION; VII. NOISY IMPLICATION FOR EVOLUTION; VIII. NETWORKS; IX. MORPHOGENETIC FIELDS: A POTENTIAL SOURCE OF VARIATION; X. IMPLICATIONS; XI. SUMMARY; ACKNOWLEDGMENTS; REFERENCES; Canalization, Cryptic Variation, and Developmental Buffering: A Critical Examination and Analytical Perspective; INTRODUCTION; I. A REVIEW OF THE REVIEWS; II. EMPIRICAL CONCERNS FOR THE STUDY OF CANALIZATION; III. DEFINITIONS OF CANALIZATION; IV. REACTION NORM OF THE MEAN (RxNM) DEFINITION OF CANALIZATION XV. THE FUTURE FOR STUDIES OF CANALIZATION
Record Nr.	UNINA-9910458710603321