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Cost Effectiveness Modelling for Health Technology Assessment : A Practical Course / / by Richard Edlin, Christopher McCabe, Claire Hulme, Peter Hall, Judy Wright
Cost Effectiveness Modelling for Health Technology Assessment : A Practical Course / / by Richard Edlin, Christopher McCabe, Claire Hulme, Peter Hall, Judy Wright
Autore Edlin Richard
Edizione [1st ed. 2015.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Adis, , 2015
Descrizione fisica 1 online resource (XIII, 208 p. 86 illus., 3 illus. in color.)
Disciplina 362.1068
Soggetto topico Pharmacy management
Medical research
Health informatics
Health economics
Pharmacoeconomics and Health Outcomes
Quality of Life Research
Health Informatics
Health Economics
ISBN 3-319-15744-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Intro -- Preface -- Acknowledgements -- Contents -- Chapter 1: Economic Evaluation, Cost Effectiveness Analysis and Health Care Resource Allocation -- 1.1 Introduction -- 1.2 Scarcity, Choice and Opportunity Cost -- 1.3 Types of Economic Evaluation -- 1.3.1 Cost Benefit Analysis (CBA) -- 1.3.2 Cost Effectiveness Analysis (CEA) -- 1.3.3 Cost Utility Analysis (CUA) -- 1.4 Incremental Cost Effectiveness Ratios (ICERs) -- 1.4.1 Simple and Extended Dominance -- 1.4.2 The Net Benefit Approach -- 1.5 Summary -- References -- Chapter 2: Finding the Evidence for Decision Analytic Cost effectiveness Models -- 2.1 Introduction -- 2.2 Choosing Resources to Search for Evidence -- 2.3 Designing Search Strategies -- 2.4 Searching for Existing Cost effectiveness Models -- 2.4.1 Where to Look -- 2.4.2 Search Strategy, Concepts, Terms and Combinations -- 2.4.3 Search Filters, Database Limits and Clinical Queries -- 2.5 Searching for Clinical Evidence -- 2.5.1 Finding the Evidence on Incidence, Prevalence and Natural History of a Disease -- 2.5.2 Finding the Evidence on the Clinical Effectiveness of Health Interventions -- 2.5.3 Database Limits and Clinical Queries -- 2.6 Finding the Evidence on Health-Related Quality of Life and Health State Preferences -- 2.6.1 Where to Look -- 2.6.2 Search Strategy, Concepts, Terms and Combinations -- 2.6.3 Search Filters, Database Limits and Clinical Queries -- 2.7 Finding Evidence on Resource Use and Costs -- 2.7.1 Where to Look -- 2.7.2 Search Strategy, Concepts, Terms and Combinations -- 2.7.3 Search Filters, Database Limits and Clinical Queries -- 2.8 Tracking and Reporting Search Activities -- 2.9 Quality Assessment Tools -- 2.10 Summary -- References -- Chapter 3: Building a Decision Tree Cost Effectiveness Model -- 3.1 Introduction -- 3.2 What Is a Decision Model? -- 3.3 Key Elements of a Decision Tree.
3.4 Costs, Benefits and Complexity -- 3.5 Exercise Building a Decision Tree -- 3.6 Summary -- References -- Chapter 4: Uncertainty, Probabilistic Analysis and Outputs from Cost Effectiveness Analyses -- 4.1 Introduction -- 4.2 Sources of Uncertainty in Cost Effectiveness Models -- 4.2.1 Sampling Variation -- 4.2.2 Extrapolation -- 4.2.3 Generalisability -- 4.2.4 Model Structure -- 4.2.5 Methodological Uncertainty -- 4.3 Analytic Responses to Uncertainty in CEA -- 4.3.1 One-Way Sensitivity Analysis -- 4.3.2 Multiway Sensitivity Analysis -- 4.3.3 Threshold Analysis -- 4.3.4 Analysis of Extremes -- 4.4 Probabilistic Sensitivity Analysis (PSA) -- 4.5 Outputs from Probabilistic Analysis -- 4.6 Some Problems with ICERs -- 4.7 Summary -- References -- Chapter 5: Introduction to Markov Cost Effectiveness Models -- 5.1 Introduction -- 5.2 Why Use Markov Models? -- 5.3 Health States -- 5.4 Transition Probabilities -- 5.5 Markov Trace -- 5.6 Cycle Length, Time Horizon and Discounting -- 5.7 Summary -- References -- Chapter 6: Probability Distributions for Effectiveness Parameters -- 6.1 Introduction -- 6.2 What Do We Mean by Effectiveness Parameters? -- 6.2.1 Obtaining Information on Effectiveness -- 6.3 Choosing Distributions for Effectiveness Parameters -- 6.3.1 Fitting a Distribution -- 6.4 Beta Distribution for Probabilities -- 6.5 Dirichlet Distribution for Multinomial Probabilities -- 6.6 Normal Distribution for Log-Relative Risk -- 6.7 Survival Analysis for Time-to-Event Data -- 6.7.1 The Exponential Distribution -- 6.7.2 The Weibull Distribution -- 6.7.3 The Gompertz Distribution -- 6.7.4 Choice of Distribution for Time-to-Event Data -- 6.8 Parameter Correlation in Survival Analysis -- 6.9 Summary -- References -- Chapter 7: Probability Distributions for Cost and Utility Parameters -- 7.1 Introduction -- 7.2 Distributions for Cost Parameters.
7.2.1 The LogNormal Distribution -- 7.2.1.1 LogNormal via Method of Moments I -- 7.2.1.2 LogNormal via Method of Moments II -- 7.2.2 The Gamma Distribution -- 7.3 Distributions for Utility Parameters -- 7.3.1 Distributional Characteristics of the Utility Scale -- 7.4 Characterising Uncertainty for Expected Utility Values Close to 1.0 -- 7.4.1 Characterising Uncertainty for Expected Utility Values Away from 1.0 -- 7.4.2 Logical Ordering for Utilities in Cost Effectiveness Models -- 7.4.3 Health State-Specific Side Effect Utility Decrements -- 7.5 Summary -- References -- Chapter 8: Correlated Parameters and the Cholesky Decomposition -- 8.1 Introduction -- 8.2 Correlated Parameters -- 8.3 Defining a Set of Correlated Parameters -- 8.4 The Cholesky Decomposition -- 8.5 What If I Need a Cholesky Decomposition for a Different Number of Variables? -- 8.6 Interpreting the Cholesky Decomposition -- 8.7 Summary -- Appendix -- Appendix 8.1: Extending the Cholesky Decomposition for More Than Three Correlated Parameters -- Chapter 9: Building a Markov Cost Effectiveness Model in Excel -- 9.1 Introduction -- 9.2 The Model -- 9.3 Modelling in Excel -- 9.4 Constructing the Parameter Table -- 9.5 Programming Your Model -- 9.6 Adding a Discount Rate, Costs and Utilities -- 9.7 Adding the Calculation of the Deterministic Incremental Cost Effectiveness Ratio (ICER) -- 9.8 Summary -- Chapter 10: Making a Markov Model Probabilistic -- 10.1 Introduction -- 10.2 Deterministic and Probabilistic Cost Effectiveness Analysis -- 10.3 Making Model Parameters Stochastic -- 10.4 Obtaining a Probabilistic Sensitivity Analysis from a Stochastic Model -- 10.5 Exercise: Probabilistic Effectiveness Parameters -- 10.6 Exercise: Probabilistic Cost and Utility Parameters -- 10.7 Exercise: Incorporating the Cholesky Decomposition -- 10.8 Summary -- Appendix.
Appendix 10.1: Optimising Visual Basic Macros in Excel -- Chapter 11: Outputs from Probabilistic Sensitivity Analysis -- 11.1 Introduction -- 11.2 Scatter Plots on the Cost Effectiveness Plane -- 11.3 Cost Effectiveness Acceptability Curves (CEACs) -- 11.4 Cost Effectiveness Acceptability Frontiers (CEAFs) -- 11.5 Scatter Plots, CEACs and CEAF Exercises -- 11.6 Summary -- References -- Chapter 12: Investing in Health Care, Research and the Value of Information -- 12.1 Introduction -- 12.2 Uncertainty and Health-Care Reimbursement Decision-­Making Processes -- 12.3 Investing in Innovative Health Technologies -- 12.4 Net Benefit Probability Map and Managing Decision Uncertainty -- 12.5 Delaying a Reimbursement Decision for More Research -- 12.5.1 Uncertainty in Decision Making and the Cost of Making the Wrong Decision -- 12.5.2 Expected Value of Perfect Information and the Value of Sample Information -- 12.5.3 Calculating the Expected Value of Perfect Information -- 12.6 Disaggregating the Value of Information: Expected Value of Perfect Parameter Information and the Expected Value of Sample Information -- 12.6.1 Expected Value of Perfect Parameter Information -- 12.6.2 Expected Value of Sample Information -- 12.7 Exercise: Constructing the Net Benefit Probability Map and Calculating the Value of Perfect Information -- 12.7.1 Calculating the Expected Value of Perfect Information -- 12.8 Summary -- References -- Chapter 13: Value of Information in Health Technology Regulation and Reimbursement -- 13.1 Introduction -- 13.2 Value of Information Analysis for Research Prioritisation -- 13.3 Value of Information Analysis for Research Design -- 13.3.1 Calculating the Expected Net Present Value of Sample Information -- 13.4 Is Decision Theory Ready to Inform Trial Design? -- 13.4.1 Structuring a Decision Problem.
13.4.2 Evidence Synthesis and Model Parameterisation -- 13.4.3 Computational and Statistical Challenges -- 13.4.4 Adoption by Regulatory Organisations and Reimbursement Agencies -- 13.4.5 Adoption by Public Research Commissioners and Clinical Trialists -- 13.4.6 Industrial Development of Health Technologies -- 13.5 Value of Information in the Evolving Regulatory and Reimbursement Environments -- 13.6 Summary -- Appendix -- Appendix 13.1: General Monte Carlo Sampling Algorithm for Calculation of Population ENPVSI -- References.
Record Nr. UNINA-9910300166503321
Edlin Richard  
Cham : , : Springer International Publishing : , : Imprint : Adis, , 2015
Materiale a stampa
Lo trovi qui: Univ. Federico II
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CVMP 2014 : proceedings of the 11th European Conference on Visual Media Production : London, UK, 13th & 14th November 2014
CVMP 2014 : proceedings of the 11th European Conference on Visual Media Production : London, UK, 13th & 14th November 2014
Autore Hall Peter
Pubbl/distr/stampa [Place of publication not identified], : ACM, 2014
Descrizione fisica 1 online resource (153 pages)
Collana ACM Other conferences
Soggetto topico Electrical & Computer Engineering
Engineering & Applied Sciences
Electrical Engineering
ISBN 1-4503-3185-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Altri titoli varianti Conference on Visual Media Production 2014
Proceedings of the 11th European Conference on Visual Media Production
CVMP '14
11th European Conference on Visual Media Production (CVMP 2014), London, United Kingdom - November 13 - 14, 2014
Record Nr. UNINA-9910375747103321
Hall Peter  
[Place of publication not identified], : ACM, 2014
Materiale a stampa
Lo trovi qui: Univ. Federico II
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La Théorie de la Régulation au fil du temps : Suivre l’évolution d’un paradigme au gré des transformations des capitalismes contemporains / / Robert Boyer
La Théorie de la Régulation au fil du temps : Suivre l’évolution d’un paradigme au gré des transformations des capitalismes contemporains / / Robert Boyer
Autore Aglietta Michel
Pubbl/distr/stampa La Plaine-Saint-Denis, : Éditions des maisons des sciences de l’homme associées, 2018
Descrizione fisica 1 online resource (450 p.)
Altri autori (Persone) AmableBruno
AndreffWladimir
BarbierJean-Claude
BatifoulierPhilippe
BazzoliLaure
BiencourtOlivier
BillaudotBernard
BourdieuJérôme
BoyerRobert
CombemalePascal
CoriatBenjamin
DehoveMario
DumenilGérard
FavereauOlivier
GadreyJean
GodardOlivier
GolubPhilip S
GuttmannRobert
HallPeter
HanadaMasanori
HanckéBob
HatchuelArmand
HugonPhilippe
InoueYasuo
IsogaiAkinori
LaredoPhilippe
LevyDominique
LiagourasGeorges
LordonFrédéric
MjøsetLars
MontagneSabine
NadelHenri
OrléanAndré
OrsiFabienne
PalombariniStefano
PerkmannMarkus
PetitPascal
PlihonDominique
RebériouxAntoine
ReynaudBénédicte
SaillardYves
SapirJacques
SchméderGeneviève
ThéretBruno
UemuraHiroyasu
VidalJean-François
VillevalMarie-Claire
WeinsteinOlivier
YamadaToshio
Soggetto topico Economics
History of Social Sciences
économie
théorie de la régulation
état des savoirs
sciences humaines et sociales
Soggetto non controllato économie
état des savoirs
sciences humaines et sociales
théorie de la régulation
ISBN 2-8218-9572-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione fre
Record Nr. UNINA-9910275030403321
Aglietta Michel  
La Plaine-Saint-Denis, : Éditions des maisons des sciences de l’homme associées, 2018
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Working families : age, gender, and daily survival in industrializing Montreal / / Bettina Bradbury
Working families : age, gender, and daily survival in industrializing Montreal / / Bettina Bradbury
Autore Bradbury Bettina <1949->
Pubbl/distr/stampa Toronto, [Canada] ; ; Buffalo, [New York] ; ; London, [England] : , : University of Toronto Press, , 1993
Descrizione fisica 1 online resource (313 p.)
Disciplina 306.85/09714/2809034
Collana Canadian Social History Series
Soggetto topico Working class families - Québec (Province) - Montréal - History - 19th century
Soggetto genere / forma Electronic books.
ISBN 0-8020-0898-4
1-4426-2316-0
1-4426-8547-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Frontmatter -- Contents -- Acknowledgments -- Introduction -- How to Use This Book -- The History of Butterfly Study in Canada -- Canadian Geography and Butterfly Distribution -- Butterfly Observation -- Butterfly Gardening -- Butterfly Conservation -- What Is a Butterfly? -- Lepidoptera Classification -- Butterfly Life History -- Butterfly Systematics -- Species Accounts -- Family Hesperiidae -- Family Papilionidae -- Family Pieridae -- Family Lycaenidae -- Family Riodinidae -- Family Nymphalidae -- Checklist of Canadian Butterflies -- Dubious Records -- Collecting Guidelines -- Appendix: Canadian Locations Mentioned in the Text -- Glossary -- Bibliography -- Index to Larval Foodplants -- Index to Butterflies
Record Nr. UNINA-9910456373903321
Bradbury Bettina <1949->  
Toronto, [Canada] ; ; Buffalo, [New York] ; ; London, [England] : , : University of Toronto Press, , 1993
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Working families : age, gender, and daily survival in industrializing Montreal / / Bettina Bradbury
Working families : age, gender, and daily survival in industrializing Montreal / / Bettina Bradbury
Autore Bradbury Bettina <1949->
Pubbl/distr/stampa Toronto, [Canada] ; ; Buffalo, [New York] ; ; London, [England] : , : University of Toronto Press, , 1993
Descrizione fisica 1 online resource (313 p.)
Disciplina 306.85/09714/2809034
Collana Canadian Social History Series
Soggetto topico Working class families - Québec (Province) - Montréal - History - 19th century
Soggetto genere / forma Statistics.
History
ISBN 1-4426-9095-X
1-4426-5572-0
0-8020-0898-4
1-4426-8547-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. The Economic, Geographic, and Social Context of Montreal Working-Class Life -- 2. Marriage, Families, and Households -- 3. Men's Wages and the Cost of Living -- 4. Age, Gender, and the Roles of Children -- 5. Managing and Stretching Wages: The Work of Wives -- 6. Managing without a Spouse: Women's Inequality Laid Bare -- Conclusion.
Record Nr. UNINA-9910781119403321
Bradbury Bettina <1949->  
Toronto, [Canada] ; ; Buffalo, [New York] ; ; London, [England] : , : University of Toronto Press, , 1993
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Working families : age, gender, and daily survival in industrializing Montreal / / Bettina Bradbury
Working families : age, gender, and daily survival in industrializing Montreal / / Bettina Bradbury
Autore Bradbury Bettina <1949->
Pubbl/distr/stampa Toronto, [Canada] ; ; Buffalo, [New York] ; ; London, [England] : , : University of Toronto Press, , 1993
Descrizione fisica 1 online resource (313 p.)
Disciplina 306.85/09714/2809034
Collana Canadian Social History Series
Soggetto topico Working class families - Québec (Province) - Montréal - History - 19th century
Soggetto genere / forma Statistics.
History
ISBN 1-4426-9095-X
1-4426-5572-0
0-8020-0898-4
1-4426-8547-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. The Economic, Geographic, and Social Context of Montreal Working-Class Life -- 2. Marriage, Families, and Households -- 3. Men's Wages and the Cost of Living -- 4. Age, Gender, and the Roles of Children -- 5. Managing and Stretching Wages: The Work of Wives -- 6. Managing without a Spouse: Women's Inequality Laid Bare -- Conclusion.
Record Nr. UNINA-9910815456703321
Bradbury Bettina <1949->  
Toronto, [Canada] ; ; Buffalo, [New York] ; ; London, [England] : , : University of Toronto Press, , 1993
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui