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I Domain Integrins / / edited by Donald Gullberg
| I Domain Integrins / / edited by Donald Gullberg |
| Edizione | [1st ed. 2014.] |
| Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014 |
| Descrizione fisica | 1 online resource (188 p.) |
| Disciplina | 572.68 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Medicine
Life sciences Medical genetics Medical biochemistry Biomedicine, general Life Sciences, general Gene Function Medical Biochemistry |
| ISBN | 94-017-9153-8 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- 1 Evolution of integrin I domains -- 2 Integrin a1b1 -- 3 Integrin a2b1 -- 4 Integrin a10b1- a collagen receptor critical in skeletal development -- 5 Integrin a11b1 – a major collagen receptor on fibroblastic cells -- 6 Regulation of integrin activity by phosphorylation -- 7 Integrin aEb7:molecular features and functional significance in the immune system -- 8 Structural aspects of integrins -- 9 Integrin recognition motifs in the human collagens -- 10 Cellular signalling by collagen-binding integrins -- 11 The therapeutic potential of I-domain integrins -- Index. |
| Record Nr. | UNINA-9910298351203321 |
| Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Integrins in Health and Disease : Key Effectors of Cell-Matrix and Cell-Cell Interactions / / Donald Gullberg and Johannes A. Eble, editors
| Integrins in Health and Disease : Key Effectors of Cell-Matrix and Cell-Cell Interactions / / Donald Gullberg and Johannes A. Eble, editors |
| Edizione | [First edition.] |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer Nature Switzerland AG, , [2023] |
| Descrizione fisica | 1 online resource (473 pages) |
| Disciplina | 572.68 |
| Collana | Biology of Extracellular Matrix Series |
| Soggetto topico | Integrins |
| ISBN | 3-031-23781-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part 1: Knockouts and animal models -- Integrins α1β1 and α2β1 – The generalist collagen receptors -- Roles for Integrin α3β1 in Development and Disease -- Part 2: Fibrosis& Cancer -- Integrins: Key targets in tissue fibrosis and tumor stroma -- Integrins in Cardiac Form, Function and Disease -- Integrin 8 and its ligand nephronectin in health and disease -- v integrin-dependent TGF activation in cancer: a brief update -- Part 3: Human disease -- a11b1, a mesenchymal collagen-binding integrin with a central role in tissue- and tumor fibrosis -- Integrins in pathological tissue remodelling of joints -- α4 integrins in immune homeostasis and disease -- β2-integrins in immunity: new roles for old players -- Structure and function of the leukocyte integrin αMβ2 -- Part 4: Integrins in hemostasis, and immune control -- Platelet integrins: Critical mediators of haemostasis and pathological thrombus formation -- Integrins as receptors for bacterial and viral pathogens. |
| Record Nr. | UNINA-9910682600603321 |
| Cham, Switzerland : , : Springer Nature Switzerland AG, , [2023] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||