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Proteomic Methods in Neuropsychiatric Research / / edited by Paul C. Guest
| Proteomic Methods in Neuropsychiatric Research / / edited by Paul C. Guest |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (XII, 370 p. 55 illus., 45 illus. in color.) |
| Disciplina | 572.6 |
| Collana | Proteomics, Metabolomics, Interactomics and Systems Biology |
| Soggetto topico |
Proteomics
Gene expression Gene therapy Gene Expression Gene Therapy |
| ISBN | 3-319-52479-8 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface – Proteomic studies in psychiatric disease and neurological disorders -- Part 1: REVIEWS -- Application of proteomic techniques for improved stratification and treatment of schizophrenia patients -- Multiplexing biomarker methods, proteomics and considerations for Alzheimer’s disease -- What have proteomic studies taught us about novel drug targets in autism? -- Application of proteomic approaches to accelerate drug development for psychiatric disorders -- Proteomic biomarker identification in cerebrospinal fluid for leptomeningeal metastases with neurological complications -- Connecting brain proteomics with behavioural neuroscience in translational animal models of neuropsychiatric disorders -- LC-MSE for qualitative and quantitative proteomicstudies of psychiatric disorders -- The utility of multiplex assays for identification of proteomic signatures in psychiatry -- Part 2: PROTOCOLS -- Blood sampling and preparation procedures for proteomic biomarker studies of psychiatric disorders -- Multiplex immunoassay profiling of serum in psychiatric disorders -- Sequential immunopreciptation of secretory vesicle proteins from biosynthetically-labelled cells -- 2d gel electrophoresis of insulin secretory granule proteins from biosynthetically-labelled pancreatic islets -- Two-dimensional gel electrophoresis: a reference protocol -- A two-dimensional difference gel electrophoresis (2D-DIGE) protocol for studies of neural precursor cells -- Identifying biomarker candidates in the blood plasma or serum proteome -- Selective reaction monitoring mass spectrometry for quantitation of glycolytic enzymes in post-mortem brain samples -- A selected reaction monitoring mass spectrometry protocol for validation of proteomic biomarker candidates in studies of psychiatric disorders -- Application of iTRAQ shotgun proteomics for measurement of brain proteins in studies of psychiatric disorders -- Co-immunoprecipitation for deciphering protein interactomes -- Sequential co-immunopreciptation and immunoblot approach to determine oligomerisation of G-protein coupled receptors -- A protocol for producing the maternal low protein rat model: a tool for pre-clinical proteomic studies -- A clinical study protocol to identify serum biomarkers predictive of response to antipsychotics in schizophrenia patients -- Generation of the acute phencyclidine rat model for proteomic studies of schizophrenia A protocol for generation of a corticosterone model of psychiatric disorders -- MK-801-treated oligodendrocytes as a cellular model to study schizophrenia -- Combining patient-reprogrammed neural cells and proteomics as a model to study psychiatric disorders -- SILAC mass spectrometry profiling: a psychiatric disorder perspective -- Preparation of peripheral blood mononuclear cells (PBMCs) as a model for proteomic studies psychiatric disorders -- Proteomic profiling of skin fibroblasts as a model of schizophrenia Proteomic profiling of the pituitary gland in studies of psychiatric disorders -- Development of an assay for measuring proprotein-conversion activity on a multiplex magnetic bead-based array platform -- Phenotyping multiple subsets of immune cells in situ in formalin-fixed, paraffin-embedded tissue sections -- Lab-on-a-chip proteomic assays for psychiatric disorders -- Development of a user-friendly app for testing blood coagulation status in schizophrenia patients -- Part 3:FUTURE PERSPECTIVES -- Proteomic approaches to enable point-of-care testing and personalized medicine for psychiatric disorders. |
| Record Nr. | UNINA-9910253912303321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Reviews on Biomarker Studies in Aging and Anti-Aging Research / / edited by Paul C. Guest
| Reviews on Biomarker Studies in Aging and Anti-Aging Research / / edited by Paul C. Guest |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (VIII, 274 p. 26 illus., 18 illus. in color.) |
| Disciplina | 572.6 |
| Collana | Proteomics, Metabolomics, Interactomics and Systems Biology |
| Soggetto topico |
Proteomics
Systems biology Human genetics Systems Biology Human Genetics |
| ISBN | 3-030-25650-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Of Mice, Whales, Jellyfish and Men: In Pursuit of Increased Longevity -- Effects on Glial Cell Glycolysis in Schizophrenia: an Advanced Aging Phenotype? -- Aging Biomarkers and Novel Targets for Anti-Aging Interventions -- Sex Differences in Aging and Associated Biomarkers -- The Therapeutic Potential of Ketogenic Diet Throughout Life: Focus on Metabolic, Neurodevelopmental and Neurodegenerative Disorders -- Coenzyme Q10 Supplementation in Fibrosis and Aging -- Dietary Restriction, Cardiovascular Aging and Age-related Cardiovascular Diseases: A Review of the Evidence -- Gut Microbiota and Microbiota-Related Metabolites as Possible Biomarkers of Cognitive Aging -- The Impact of Herbal Products in the Prevention, Regeneration and Delay of Skin Aging -- Epigenetic Clock: Just a Convenient Marker or an Active Driver of Aging? -- From White to Brown – Adipose Tissue is Critical to the Extended Lifespan and Healthspan of Growth Hormone Mutant Mice -- The Cytoskeleton as a Modulator of Aging and Neurodegeneration -- Metabolic Biomarkers in Aging and Anti-Aging Research. |
| Record Nr. | UNINA-9910349445203321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders / / edited by Paul C. Guest
| Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders / / edited by Paul C. Guest |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (XIII, 328 p. 28 illus., 26 illus. in color.) |
| Disciplina | 570 |
| Collana | Proteomics, Metabolomics, Interactomics and Systems Biology |
| Soggetto topico |
Systems biology
Proteomics Gene expression Systems Biology Gene Expression |
| ISBN | 3-030-05542-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. The Potential of ‘Omics to Link Lipid Metabolism and Genetic and Comorbidity Risk Factors of Alzheimer’s Disease in African Americans -- 2. The Role of Biomarkers in Alzheimer’s Disease Drug Development -- 3. Mitochondrial Involvement in Mental Disorders; Energy Metabolism, Genetic and Environmental Factors -- 4. Lymphocytes, Platelets, Erythrocytes and Exosomes as Possible Biomarkers for Alzheimer's Disease Clinical Diagnosis -- 5. Genetic Risk Factors for Alzheimer Disease: Emerging Roles of Microglia in Disease Pathomechanisms -- 6. Neuroimaging Studies of Cognitive Function in Schizophrenia -- 7. The Role of Biomarkers in Psychiatry -- 8. Interactome Studies of Psychiatric Disorders -- 9. MicroRNAs in Major Depressive Disorder -- 10. Proteomic Markers for Depression -- 11. Advances in Biomarker Studies in Autism Spectrum Disorders -- 12. Proteomic Investigations of Autism Spectrum Disorder: Past Findings, Current Challenges and Future Prospects -- 13. Role of the Gut Microbiome in Autism Spectrum Disorders -- 14. Metabolomic Biomarkers in Mental Disorders: Bipolar Disorder and Schizophrenia -- 15. Early Detection and Treatment of Patients with Alzheimer’s Disease: Future Perspectives. |
| Record Nr. | UNINA-9910337938103321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Reviews on Biomarker Studies of Metabolic and Metabolism-Related Disorders / / edited by Paul C. Guest
| Reviews on Biomarker Studies of Metabolic and Metabolism-Related Disorders / / edited by Paul C. Guest |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (309 pages) |
| Disciplina | 610.28 |
| Collana | Proteomics, Metabolomics, Interactomics and Systems Biology |
| Soggetto topico |
Proteomics
Medical genetics Diabetes Gene Function |
| ISBN | 3-030-12668-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. Insulin Resistance in Schizophrenia -- 2. Biogenesis of the Insulin Secretory Granule in Health and Disease -- 3. Current Models of Fatty Liver Disease; New Insights, Therapeutic Targets and Interventions -- 4. Preclinical Models of Altered Early Life Nutrition and Development of Reproductive Disorders in Female Offspring -- 5. Targeting Mitochondrial Defects to Increase Lngevity in Animal Models of Neurodegenerative Diseases -- 6. Computational Approaches for Identification of Pleiotropic Biomarker Profiles in Psychiatry -- 7. MiRNA Regulation of Glucose and Lipid Metabolism in Relation to Diabetes and Non-Alcoholic Fatty Liver Disease -- 8. Hypercaloric Diet-Induced Obesity and Obesity-Related Metabolic Disorders in Experimental Models -- 9. Metabolic Biomarkers in Nematode C. elegans During Aging -- 10. Circular RNAs as potential biomarkers and therapeutic targets for metabolic diseases -- 11. Deciphering Endothelial Dysfunction in the HIV-Infected Population -- 12. The Role of Inflammation in the Development of GDM and The Use of Markers of Inflammation in GDM Screening -- 13. PFKP Signaling at a Glance: an Emerging Mediator of Cancer Cell Metabolism -- 14. ATAD3A on the Path to Cancer -- 15. Impact of Exercise on Inflammatory Mediators of Metabolic and Vascular Insulin Resistance in Type 2 Diabetes. |
| Record Nr. | UNINA-9910337956603321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Reviews on New Drug Targets in Age-Related Disorders / / edited by Paul C. Guest
| Reviews on New Drug Targets in Age-Related Disorders / / edited by Paul C. Guest |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
| Descrizione fisica | 1 online resource (viii, 340 pages) : illustrations |
| Disciplina | 615.7 |
| Collana | Proteomics, Metabolomics, Interactomics and Systems Biology |
| Soggetto topico |
Proteomics
Metabolism Pharmaceutical technology Geriatrics Systems biology Metabolomics Pharmaceutical Sciences/Technology Geriatrics/Gerontology Systems Biology Geriatria Malalties de les persones grans Farmacologia |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-42667-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Ch-01 Targeting ROS-mediated Crosstalk between Autophagy and Apoptosis in Cancer -- Ch-02 Micronutrients that Affect Immunosenescence -- Ch-03 Bioactive Lipids in Age-Related Disorders -- Ch-04 Effect of Short Chain Fatty Acids on Age-Related Disorders -- Ch-05 The Effects of Parabiosis on Aging and Age-related Diseases -- Ch-06 Skeletal Muscle Aging Atrophy: Assessment and Exercise-Based Treatment -- Ch-07 Polyphenols as an Effective Therapeutic Intervention Against Cognitive Decline during Normal and Pathological Brain Aging -- Ch-08 Early Diagnosis and Targeted Treatment Strategy for Improved Therapeutic Outcomes in Alzheimer’s Disease -- Ch-09 Resetting the Aging Clock: Implications for Managing Age-Related Diseases -- Ch-10 The Challenge of Antidepressant Therapeutics in Alzheimer's Disease -- Ch-11 Anxiolytic Terpenoids and Aromatherapy for Anxiety and Depression -- Ch-12 The Role of Nutrition in Attenuating Age-Related Skeletal Muscle Atrophy -- Ch-13 The Use of Metformin to Increase the Human Healthspan. |
| Record Nr. | UNINA-9910409697503321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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